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2016

Conference Publication

Locus Discovery in Genome-wide Association Studies using Bivariate Analysis

Warrington, Nicole M. and Evans, David M. (2016). Locus Discovery in Genome-wide Association Studies using Bivariate Analysis. Annual Meeting of the International-Genetic-Epidemiology-Society, Toronto Canada, Oct 24-26, 2016. HOBOKEN: WILEY-BLACKWELL.

Locus Discovery in Genome-wide Association Studies using Bivariate Analysis

2016

Conference Publication

New opportunities for structural equation modelling in the post GWAS era

Evans, David (2016). New opportunities for structural equation modelling in the post GWAS era. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.

New opportunities for structural equation modelling in the post GWAS era

2016

Conference Publication

LD hub and MR-base: online platforms for preforming LD score regression and Mendelian randomization analysis using GWAS summary data

Zheng, Jie, Haycock, Philip, Hemani, Gibran, Elsworth, Benjamin, Shihab, Hashem, Laurin, Charles, Erzurumluoglu, Mesut, Howe, Laurence, Wade, Kaitlin, Warrington, Nicole, Finucane, Hilary, Price, Alkes, Anttila, Verneri, Paternoster, Lavinia, Martin, Richard, Relton, Caroline, Gaunt, Tom, Smith, George Davey, Neale, Benjamin and Evans, David (2016). LD hub and MR-base: online platforms for preforming LD score regression and Mendelian randomization analysis using GWAS summary data. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.

LD hub and MR-base: online platforms for preforming LD score regression and Mendelian randomization analysis using GWAS summary data

2016

Conference Publication

Genome-wide association study of 6,939 individuals identifies five novel loci and suggests that prenatal exposure to testosterone is not a major determinant of individual differences in 2D:4D finger ratio

Warrington, Nicole, Hemani, Gibran, Hysi, Pirro, Mangino, Massimo, McMahon, George, Hickey, Martha, Wolke, Dieter, Montgomery, Grant, Pennell, Craig, Spector, Tim, Martin, Nicholas, Medland, Sarah and Evans, David (2016). Genome-wide association study of 6,939 individuals identifies five novel loci and suggests that prenatal exposure to testosterone is not a major determinant of individual differences in 2D:4D finger ratio. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.

Genome-wide association study of 6,939 individuals identifies five novel loci and suggests that prenatal exposure to testosterone is not a major determinant of individual differences in 2D:4D finger ratio

2016

Conference Publication

Can Mendelian randomization inform drug development research for neurobehavioural conditions? A study of Alzheimer's disease

Brion, Marie-Jo, Benyamin, Beben, Smith, George Davey, McGrath, John and Evans, David (2016). Can Mendelian randomization inform drug development research for neurobehavioural conditions? A study of Alzheimer's disease. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.

Can Mendelian randomization inform drug development research for neurobehavioural conditions? A study of Alzheimer's disease

2016

Conference Publication

Detecting parent of origin effects using GREML of transmitted genotypes

Laurin, Charles, Hemani, Gibran and Evans, David (2016). Detecting parent of origin effects using GREML of transmitted genotypes. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.

Detecting parent of origin effects using GREML of transmitted genotypes

2016

Conference Publication

Trait-specific patterns of common genetic factors influence social communication difficulties and ADHD symptoms during development

St Pourcain, Beate, Eaves, Lindon, Evans, David, Fisher, Simon, Carey, Greg and Smith, George Davey (2016). Trait-specific patterns of common genetic factors influence social communication difficulties and ADHD symptoms during development. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.

Trait-specific patterns of common genetic factors influence social communication difficulties and ADHD symptoms during development

2016

Journal Article

Genome-wide associations for birth weight and correlations with adult disease

Horikoshi, Momoko, Beaumont, Robin N., Day, Felix R., Warrington, Nicole M., Kooijman, Marjolein N., Fernandez-Tajes, Juan, Feenstra, Bjarke, van Zuydam, Natalie R., Gaulton, Kyle J., Grarup, Niels, Bradfield, Jonathan P., Strachan, David P., Li-Gao, Ruifang, Ahluwalia, Tarunveer S., Kreiner, Eskil, Rueedi, Rico, Lyytikainen, Leo-Pekka, Cousminer, Diana L., Wu, Ying, Thiering, Elisabeth, Wang, Carol A., Have, Christian T., Hottenga, Jouke-Jan, Vilor-Tejedor, Natalia, Joshi, Peter K., Boh, Eileen Tai Hui, Ntalla, Ioanna, Pitkanen, Niina, Mahajan, Anubha ... Freathy, Rachel M. (2016). Genome-wide associations for birth weight and correlations with adult disease. Nature, 538 (7624), 248-252. doi: 10.1038/nature19806

Genome-wide associations for birth weight and correlations with adult disease

2016

Journal Article

Why internal weights should be avoided (not only) in MR-Egger regression response

Kemp, John P., Sayers, Adrian, Smith, George Davey, Tobias, Jonathan H. and Evans, David M. (2016). Why internal weights should be avoided (not only) in MR-Egger regression response. International Journal of Epidemiology, 45 (5), 1678-1679. doi: 10.1093/ije/dyw241

Why internal weights should be avoided (not only) in MR-Egger regression response

2016

Journal Article

Using Mendelian randomization to investigate a possible causal relationship between adiposity and increased bone mineral density at different skeletal sites in children

Kemp, John P., Sayers, Adrian, Smith, George Davey, Tobias, Jonathan H. and Evans, David M. (2016). Using Mendelian randomization to investigate a possible causal relationship between adiposity and increased bone mineral density at different skeletal sites in children. International Journal of Epidemiology, 45 (5), 1560-1572. doi: 10.1093/ije/dyw079

Using Mendelian randomization to investigate a possible causal relationship between adiposity and increased bone mineral density at different skeletal sites in children

2016

Journal Article

Heritability and genome-wide association analyses of sleep duration in children: the EAGLE consortium

Marinelli, Marcella, Pappa, Irene, Bustamante, Mariona, Bonilla, Carolina, Suarez, Anna, Tiesler, Carla M., Vilor-Tejedor, Natalia, Zafarmand, Mohammad Hadi, Alvarez-Pedrerol, Mar, Andersson, Sture, Bakermans-Kranenburg, Marian J., Estivill, Xavier, Evans, David M., Flexeder, Claudia, Forns, Joan, Gonzalez, Juan R., Guxens, Monica, Huss, Anke, van IJzendoorn, Marinus H., Jaddoe, Vincent W. V., Julvez, Jordi, Lahti, Jari, Lopez-Vicente, Monica, Lopez-Espinosa, Maria-Jose, Manz, Judith, Mileva-Seitz, Viara R., Perola, Markus, Pesonen, Anu-Katriina, Rivadeneira, Fernando ... Sunyer, Jordi (2016). Heritability and genome-wide association analyses of sleep duration in children: the EAGLE consortium. Sleep, 39 (10), 1859-1869. doi: 10.5665/sleep.6170

Heritability and genome-wide association analyses of sleep duration in children: the EAGLE consortium

2016

Journal Article

A genome-wide association meta-analysis of attention-deficit/hyperactivity disorder symptoms in population-based pediatric cohorts

Middeldorp, Christel M., Hammerschlag, Anke R., Ouwens, Klaasjan G., Groen-Blokhuis, Maria M., St Pourcain, Beate, Greven, Corina U., Pappa, Irene, Tiesler, Carla M. T., Ang, Wei, Nolte, Ilja M., Vilor-Tejedor, Natalia, Bacelis, Jonas, Ebejer, Jane L., Zhao, Huiying, Davies, Gareth E., Ehli, Erik A., Evans, David M., Fedko, Iryna O., Guxens, Monica, Hottenga, Jouke-Jan, Hudziak, James J., Jugessur, Astanand, Kemp, John P., Krapohl, Eva, Martin, Nicholas G., Murcia, Mario, Myhre, Ronny, Ormel, Johan, Ring, Susan M. ... Boomsma, Dorret I. (2016). A genome-wide association meta-analysis of attention-deficit/hyperactivity disorder symptoms in population-based pediatric cohorts. Journal of the American Academy of Child and Adolescent Psychiatry, 55 (10), 896-905.e6. doi: 10.1016/j.jaac.2016.05.025

A genome-wide association meta-analysis of attention-deficit/hyperactivity disorder symptoms in population-based pediatric cohorts

2016

Journal Article

A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways

Bustamante, Mariona, Standl, Marie, Bassat, Quique, Vilor-Tejedor, Natalia, Medina-Gomez, Carolina, Bonilla, Carolina, Ahluwalia, Tarunveer S., Bacelis, Jonas, Bradfield, Jonathan P., Tiesler, Carla M. T., Rivadeneira, Fernando, Ring, Susan, Vissing, Nadja H., Fink, Nadia R., Jugessur, Astanand, Mentch, Frank D., Ballester, Ferran, Kriebel, Jennifer, Kiefte-de Jong, Jessica C., Wolsk, Helene M., Llop, Sabrina, Thiering, Elisabeth, Beth, Systke A., Timpson, Nicholas J., Andersen, Josefine, Schulz, Holger, Jaddoe, Vincent W. V., Evans, David M., Waage, Johannes ... Sunyer, Jordi (2016). A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways. Human Molecular Genetics, 25 (18), 4127-4142. doi: 10.1093/hmg/ddw264

A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways

2016

Conference Publication

OP03 The effect of in utero exposure to alcohol, tobacco and cannabis on educational attainment in adolescence: findings from ALSPAC, a UK cohort study

Teyhan, A, Evans, D and Macleod, J (2016). OP03 The effect of in utero exposure to alcohol, tobacco and cannabis on educational attainment in adolescence: findings from ALSPAC, a UK cohort study. doi: 10.1136/jech-2016-208064.3

OP03 The effect of in utero exposure to alcohol, tobacco and cannabis on educational attainment in adolescence: findings from ALSPAC, a UK cohort study

2016

Journal Article

Genome-wide association study of copy number variation with lung function identifies a novel signal of association near BANP for forced vital capacity

Shrine, Nick, Tobin, Martin D., Schurmann, Claudia, Artigas, Maria Soler, Hui, Jennie, Lehtimaki, Terho, Raitakari, Olli T., Pennell, Craig E., Ang, Qi Wei, Strachan, David P., Homuth, Georg, Glaeser, Sven, Felix, Stephan B., Evans, David M., Henderson, John, Granell, Raquel, Palmer, Lyle J., Huffman, Jennifer, Hayward, Caroline, Scotland, Generation, Malarstig, Anders, Musk, Bill, James, Alan L. and Wain, Louise V. (2016). Genome-wide association study of copy number variation with lung function identifies a novel signal of association near BANP for forced vital capacity. BMC Genetics, 17 (1) 116, 1-8. doi: 10.1186/s12863-016-0423-0

Genome-wide association study of copy number variation with lung function identifies a novel signal of association near BANP for forced vital capacity

2016

Journal Article

Erratum to: Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence

Pourcain, Beate St, Haworth, C. M. A., Davis, O. S. P., Wang, Kai, Timpson, Nicholas J., Evans, David M., Kemp, John P., Ronald, Angelica, Price, Tom, Meaburn, Emma, Ring, Susan M., Golding, Jean, Hakonarson, Hakon, Plomin, R. and Smith, George Davey (2016). Erratum to: Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence. Human Genetics, 135 (8), 965-965. doi: 10.1007/s00439-016-1695-1

Erratum to: Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence

2016

Journal Article

Joint developmental trajectories of internalizing and externalizing disorders between childhood and adolescence

Nivard, Michel G., Lubke, Gitta H., Dolan, Conor V., Evans, David M., St. Pourcain, Beate, Munafo, Marcus R. and Middeldorp, Christel M. (2016). Joint developmental trajectories of internalizing and externalizing disorders between childhood and adolescence. Development and Psychopathology, 29 (3), 1-10. doi: 10.1017/S0954579416000572

Joint developmental trajectories of internalizing and externalizing disorders between childhood and adolescence

2016

Journal Article

International genome-wide association study consortium identifies novel loci associated with blood pressure in children and adolescents

Parmar, Priyakumari Ganesh, Taal, H. Rob, Timpson, Nicholas J., Thiering, Elisabeth, Lehtimaki, Terho, Marinelli, Marcella, Lind, Penelope A., Howe, Laura D., Verwoert, Germaine, Aalto, Ville, Uitterlinden, Andre G., Briollais, Laurent, Evans, Dave M., Wright, Margie J., Newnham, John P., Whitfield, John B., Lyytikainen, Leo-Pekka, Rivadeneira, Fernando, Boomsma, Dorrett I., Viikari, Jorma, Gillman, Matthew W., St Pourcain, Beate, Hottenga, Jouke-Jan, Montgomery, Grant W., Hofman, Albert, Kahonen, Mika, Martin, Nicholas G., Tobin, Martin D., Raitakari, Ollie ... Palmer, Lyle J. (2016). International genome-wide association study consortium identifies novel loci associated with blood pressure in children and adolescents. Circulation: Cardiovascular Genetics, 9 (3), 266-278. doi: 10.1161/CIRCGENETICS.115.001190

International genome-wide association study consortium identifies novel loci associated with blood pressure in children and adolescents

2016

Journal Article

The case for genome-wide association studies of bone acquisition in paediatric and adolescent populations

Kemp, John P, Medina-Gomez, Carolina, Tobias, Jonathan H, Rivadeneira, Fernando and Evans, David M (2016). The case for genome-wide association studies of bone acquisition in paediatric and adolescent populations. BoneKEy reports, 5, 796. doi: 10.1038/bonekey.2016.23

The case for genome-wide association studies of bone acquisition in paediatric and adolescent populations

2016

Journal Article

Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: the CREAM Consortium

Fan, Qiao, Guo, Xiaobo, Tideman, J. Willem L., Williams, Katie M., Yazar, Seyhan, Hosseini, S. Mohsen, Howe, Laura D., St Pourcain, Beate, Evans, David M., Timpson, Nicholas J., McMahon, George, Hysi, Pirro G., Krapohl, Eva, Wang, Ya Xing, Jonas, Jost B., Baird, Paul Nigel, Wang, Jie Jin, Cheng, Ching-Yu, Teo, Yik-Ying, Wong, Tien-Yin, Ding, Xiaohu, Wojciechowski, Robert, Young, Terri L., Parssinen, Olavi, Oexle, Konrad, Pfeiffer, Norbert, Bailey-Wilson, Joan E., Paterson, Andrew D., Klaver, Caroline C. W. ... Guggenheim, Jeremy A. (2016). Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: the CREAM Consortium. Scientific Reports, 6 (1) 25853, 25853. doi: 10.1038/srep25853

Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: the CREAM Consortium