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2017 Journal Article Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locusMedina-Gomez, Carolina, Kemp, John P., Dimou, Niki L., Kreiner, Eskil, Chesi, Alessandra, Zemel, Babette S., Bonnelykke, Klaus, Boer, Cindy G., Ahluwalia, Tarunveer S., Bisgaard, Hans, Evangelou, Evangelos, Heppe, Denise H. M., Bonewald, Lynda F., Gorski, Jeffrey P., Ghanbari, Mohsen, Demissie, Serkalem, Duque, Gustavo, Maurano, Matthew T., Kiel, Douglas P., Hsu, Yi-Hsiang, Van Der Eerden, Bram C. J., Ackert-Bicknell, Cheryl, Reppe, Sjur, Gautvik, Kaare M., Raastad, Truls, Karasik, David, Van De Peppel, Jeroen, Jaddoe, Vincent W. V., Uitterlinden, André G. ... Rivadeneira, Fernando (2017). Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus. Nature Communications, 8 (1) 121, 121. doi: 10.1038/s41467-017-00108-3 |
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2017 Journal Article Association between telomere length and risk of cancer and non-neoplastic diseases a Mendelian randomization studyHaycock, Philip C., Burgess, Stephen, Nounu, Aayah, Zheng, Jie, Okoli, George N., Bowden, Jack, Wade, Kaitlin Hazel, Timpson, Nicholas J., Evans, David M., Willeit, Peter, Aviv, Abraham, Gaunt, Tomr., Hemani, Gibran, Mangino, Massimo, Ellis, Hayley Patricia, Kurian, Kathreena M., Pooley, Karen A., Eeles, Rosalind A., Lee, Jeffrey E., Fang, Shenying, Chen, Wei V., Law, Matthew H., Bowdler, Lisa M., Iles, Mark M., Yang, Qiong, Worrall, Bradford B., Markus, Hugh Stephen, Hung, Rayjean J., Amos, Chris I. ... Smith, George Davey (2017). Association between telomere length and risk of cancer and non-neoplastic diseases a Mendelian randomization study. JAMA Oncology, 3 (5), 636-651. doi: 10.1001/jamaoncol.2016.5945 |
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2017 Journal Article Epigenome-wide association of DNA methylation in whole blood with bone mineral densityMorris, John A., Tsai, Pei-Chien, Joehanes, Roby, Zeng, Jie, Trajanoska, Katerina, Soerensen, Mette, Forgetta, Vincenzo, Castillo-Fernandez, Juan Edgar, Frost, Morten, Spector, Tim D., Christensen, Kaare, Christiansen, Lene, Rivadeneira, Fernando, Tobias, Jonathan H., Evans, David M., Kiel, Douglas P., Hsu, Yi-Hsiang, Richards, J. Brent and Bell, Jordana T. (2017). Epigenome-wide association of DNA methylation in whole blood with bone mineral density. Journal of Bone and Mineral Research, 32 (8), 1644-1650. doi: 10.1002/jbmr.3148 |
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2017 Journal Article Pharmacogenetics of antidepressant response: a polygenic approachGarcía-González, Judit, Tansey, Katherine E., Hauser, Joanna, Henigsberg, Neven, Maier, Wolfgang, Mors, Ole, Placentino, Anna, Rietschel, Marcella, Souery, Daniel, Žagar, Tina, Czerski, Piotr M., Jerman, Borut, Buttenschøn, Henriette N., Schulze, Thomas G., Zobel, Astrid, Farmer, Anne, Aitchison, Katherine J., Craig, Ian, McGuffin, Peter, Giupponi, Michel, Perroud, Nader, Bondolfi, Guido, Evans, David, O'Donovan, Michael, Peters, Tim J., Wendland, Jens R., Lewis, Glyn, Kapur, Shitij, Perlis, Roy ... Fabbri, Chiara (2017). Pharmacogenetics of antidepressant response: a polygenic approach. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 75, 128-134. doi: 10.1016/j.pnpbp.2017.01.011 |
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2017 Journal Article Shared genetic influences between dimensional ASD and ADHD symptoms during child and adolescent developmentStergiakouli, Evie, Davey Smith, George, Martin, Joanna, Skuse, David H., Viechtbauer, Wolfgang, Ring, Susan M., Ronald, Angelica, Evans, David E., Fisher, Simon E., Thapar, Anita and St Pourcain, Beate (2017). Shared genetic influences between dimensional ASD and ADHD symptoms during child and adolescent development. Molecular Autism, 8 (1) 18, 18. doi: 10.1186/s13229-017-0131-2 |
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2017 Other Outputs Maternal and fetal genetic contribution to gestational weight gainWarrington, Nicole M, Richmond, Rebecca, Fenstra, Bjarke, Myhre, Ronny, Gaillard, Romy, Paternoster, Lavinia, Wang, Carol A, Beaumont, Robin N, Das, Shikta, Murcia, Mario, Barton, Sheila J, Espinosa, Ana, Theiring, Elisabeth, Atalay, Mustafa, Pitkänen, Niina, Ntalla, Ioanna, Jonsson, Anna E, Freathy, Rachel, Karhunen, Ville, Tiesler, Carla MT, Allard, Catherine, Crawford, Andrew, Ring, Susan M, Melbye, Mads, Magnus, Per, Rivadeneira, Fernando, Skotte, Line, Hansen, Torben, Marsh, Julie ... consortium, Early Growth Genetics (2017). Maternal and fetal genetic contribution to gestational weight gain. doi: 10.1101/116434 |
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2017 Journal Article Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targetsWain, Louise V., Shrine, Nick, Artigas, María Soler, Erzurumluoglu, A. Mesut, Noyvert, Boris, Bossini-Castillo, Lara, Obeidat, Ma’en, Henry, Amanda P., Portelli, Michael A., Hall, Robert J., Billington, Charlotte K., Rimington, Tracy L., Fenech, Anthony G., John, Catherine, Blake, Tineka, Jackson, Victoria E., Allen, Richard J., Prins, Bram P., Campbell, Archie, Porteous, David J., Jarvelin, Marjo-Riitta, Wielscher, Matthias, James, Alan L., Hui, Jennie, Wareham, Nicholas J., Zhao, Jing Hua, Wilson, James F., Joshi, Peter K., Stubbe, Beate ... Tobin, Martin D. (2017). Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nature Genetics, 49 (3), 416-425. doi: 10.1038/ng.3787 |
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2017 Journal Article Using Mendelian randomization to determine causal effects of maternal pregnancy (intrauterine) exposures on offspring outcomes: Sources of bias and methods for assessing themLawlor, Deborah, Richmond, Rebecca, Warrington, Nicole , McMahon, George, Davery Smith, George, Bowden, Jack and Evans, David M. (2017). Using Mendelian randomization to determine causal effects of maternal pregnancy (intrauterine) exposures on offspring outcomes: Sources of bias and methods for assessing them. Wellcome Open Research, 2 (11) 11, 11. doi: 10.12688/wellcomeopenres.10567.1 |
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2017 Journal Article LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysisZheng, Jie, Erzurumluoglu, A. Mesut, Elsworth, Benjamin L., Kemp, John P., Howe, Laurence, Haycock, Philip C., Hemani, Gibran, Tansey, Katherine, Laurin, Charles, St Pourcain, Beate, Warrington, Nicole M., Finucane, Hilary K., Price, Alkes L., Bulik-Sullivan, Brendan K., Anttila, Verneri, Paternoster, Lavinia, Gaunt, Tom R., Evans, David M. and Neale, Benjamin M. (2017). LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis. Bioinformatics, 33 (2), 272-279. doi: 10.1093/bioinformatics/btw613 |
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2017 Conference Publication Common polygenic risk for ASD and ADHD is associated with childhood linguistic traits within the general population, but with opposite effectsSt Pourcain, Beate, Verhoef, Ellen, Fisher, Simon E., Stergiakouli, Evie, Evans, David E., Ring, Susan M. and Smith, George Davey (2017). Common polygenic risk for ASD and ADHD is associated with childhood linguistic traits within the general population, but with opposite effects. 24th World Congress of Psychiatric Genetics (WCPG), Jerusalem Israel, October 30-November 4 2016. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2016.09.470 |
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2017 Conference Publication Genome-wide association study identifies three novel genetic determinants of dental maturationGrgic, Olja, Medina-Gomez, Carolina, Dhamo, Brunilda, Trajanoska, Katerina, Vucic, Strahinja, Ongkosuwito, Edwin M., Jaddoe, Vincent W. V., Uitterlinden, Andre G., Jarvelin, Marjo-Riitta, Timpson, Nicholas, Evans, David M., Wolvius, Eppo B. and Rivadeneira, Fernando (2017). Genome-wide association study identifies three novel genetic determinants of dental maturation. Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), Denver, CO USA, 8-11 September 2017. Hoboken, NJ United States: Wiley-Blackwell Publishing. |
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2017 Conference Publication Trait-specific patterns of common genetic factors influence social-communication difficulties and ADHD symptoms during child and adolescent developmentSt Pourcain, Beate, Eaves, Lindon, Evans, David M., Stergiakouli, Evie, Fisher, Simon E., Ring, Susan M., Carey, Gregory and George, Davey Smith (2017). Trait-specific patterns of common genetic factors influence social-communication difficulties and ADHD symptoms during child and adolescent development. 24th World Congress of Psychiatric Genetics (WCPG), Jerusalem Israel, October 30 - November 4 2016. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2016.09.411 |
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2017 Conference Publication Performing Mendelian randomization using structural equation modelsEvans, David and Warrington, Nicole (2017). Performing Mendelian randomization using structural equation models. 47th Annual Meeting of the Behavior-Genetics-Association (BGA), Oslo Norway, 28 June - 1 July 2017. New York NY United States: Springer. |
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2017 Conference Publication Cathepsins B and S Are Novel Biomarkers for Bone Mineral Density: A Mendelian Randomization StudyMorris, John, Kemp, John, Evans, David and Richards, Brent (2017). Cathepsins B and S Are Novel Biomarkers for Bone Mineral Density: A Mendelian Randomization Study. Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), Denver CO, United States, 8-11 September 2017. Hoboken, NJ United States: Wiley. |
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2017 Conference Publication Genetic links between social-communication traits, ADHD traits and clinical ADHD during developmentSt Pourcain, Beate, Martin, Joanna, Stergiakouli, Evie, Robinson, Elise, Skuse, David, Susan, Ring, Ronald, Angelica, Evans, David, Timpson, Nicholas, Thapar, Anita and Smith, George Davey (2017). Genetic links between social-communication traits, ADHD traits and clinical ADHD during development. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, Oct 16-20 2015. Amsterdam, Netherlands: Elsevier. |
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2017 Conference Publication Developmental changes in genetic relationships between traits and disease: Analyses of genetic overlaps between social-communication difficulties, autism spectrum disorders and schizophreniaSt Pourcain, Beate, Robinson, Elise, Bulik-Sullivan, Brendan, Anttila, Verneri, Maller, Julian, Skuse, David, Rings, Susan, Evans, David, Timpson, Nicholas, Ronald, Angelica, Grove, Jakob, Borglum, Anders, Mortensen, Preben Bo, Daly, Mark and Smiths, George Davey (2017). Developmental changes in genetic relationships between traits and disease: Analyses of genetic overlaps between social-communication difficulties, autism spectrum disorders and schizophrenia. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, Oct 16-20 2015. Amsterdam, Netherlands: Elsevier. |
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2017 Conference Publication Genome-wide association study of extreme high bone mass identifies NPR3 as a novel BMD-associated gene and highlights the contribution of common genetic variation to extreme BMD phenotypesGregson, Celia, Newell, Felicity, Leo, Paul, Paternoster, Lavinia, Marshall, Mhairi, Clark, Graeme, Morris, John, Ge, Bing, Bao, Xiao, Bassett, Duncan, Williams, Graham, Youlten, Scott, Croucher, Peter, Smith, George Davey, Evans, David, Kemp, John, Brown, Matthew, Tobias, Jon and Duncan, Emma (2017). Genome-wide association study of extreme high bone mass identifies NPR3 as a novel BMD-associated gene and highlights the contribution of common genetic variation to extreme BMD phenotypes. Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), Denver CO, United States, 8-11 September 2017. Hoboken, NJ United States: Wiley. |
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2017 Conference Publication Estimating developmental changes within the genetic architecture of social communication traits: a multivariate study of genetic variance in unrelated individualsSt Pourcain, Beate, Eaves, Lindon, Verhoef, Ellen, Shapland, Chin Yang, Ring, Susan M., Fisher, Simon E., Medland, Sarah, Evans, David and Smith, George Davey (2017). Estimating developmental changes within the genetic architecture of social communication traits: a multivariate study of genetic variance in unrelated individuals. 47th Annual Meeting of the Behavior-Genetics-Association (BGA), Oslo Norway, Jun 28-Jul 01, 2017. New York, NY, United States: Springer. |
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2017 Journal Article HAPRAP: a haplotype-based iterative method for statistical fine mapping using GWAS summary statisticsZheng, Jie, Rodriguez, Santiago, Laurin, Charles, Baird, Denis, Trela-Larsen, Lea, Erzurumluoglu, Mesut A., Zheng, Yi, White, Jon, Giambartolomei, Claudia, Zabaneh, Delilah, Morris, Richard, Kumari, Meena, Casas, Juan P., Hingorani, Aroon D., Evans, David M. , Gaunt, Tom R. and Day, Ian N. M. (2017). HAPRAP: a haplotype-based iterative method for statistical fine mapping using GWAS summary statistics. Bioinformatics, 33 (1), 79-86. doi: 10.1093/bioinformatics/btw565 |
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2016 Other Outputs MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associationsHemani, Gibran, Zheng, Jie, Wade, Kaitlin H, Laurin, Charles, Elsworth, Benjamin, Burgess, Stephen, Bowden, Jack, Langdon, Ryan, Tan, Vanessa, Yarmolinsky, James, Shihab, Hashem A., Timpson, Nicholas, Evans, David M, Relton, Caroline, Martin, Richard M, Smith, George Davey, Gaunt, Tom R, Haycock, Philip C, Soranzo, Nicole, van Heel, David A, Okada, Yukinori, Tang, Clara S., Garcia-Barcelo, Merce, Tam, Paul KH, Jacobsen, Kaya Kvarme, Jones, Gregory T, Bown, Matthew J, Albagha, Omar, Ralston, Stuart H. ... Lee, Jeffrey E (2016). MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations. doi: 10.1101/078972 |
