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2012 Conference Publication Hypoxia and E-selectin are opposite regulators of hematopoietic stem cell quiescence in the nicheLevesque, Jean-Pierre, Forristal, Catherine and Winkler, Ingrid (2012). Hypoxia and E-selectin are opposite regulators of hematopoietic stem cell quiescence in the niche. 41st Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Amsterdam Netherlands, 23-26 August 2012. Philadelphia, PA United States: Elsevier. |
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2012 Conference Publication Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia by human AML oncogenes, and represents a potential therapeutic targetPattabiraman, Diwakar R., Shakhbazov, Konstantin, Barbier, Valerie, McGirr, Crystal, Krishnan, Keerthana, Mukhopadhyay, Pamela, Hawthorne, Paula, Trezise, Ann, Grimmond, Sean, Papathanasiou, Peter, Perkins, Andrew C., Levesque, Jean-Pierre, Alexander, Warren S., Winkler, Ingrid G. and Gonda, Thomas J. (2012). Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia by human AML oncogenes, and represents a potential therapeutic target. 54th Annual Meeting and Exposition of the American Society of Hematology (ASH), Atlanta, GA, United States, 8-11 Deceember, 2012. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V120.21.2402.2402 |
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2011 Conference Publication Oxygen-Independent Stabilization of the Oxygen-Labile Transcription Factor HIF-1 alpha with Dimethyloxalyl Glycine or FG-4497 Increases Hematopoietic Stem Cell Quiescence In Vivo and Mobilization in Response to G-CSFForristal, Catherine, Nowlan, Bianca, Barbier, Valerie, McCarthy, Domenica, Walkinshaw, Gail, Winkler, Ingrid G. and Levesque, Jean-Pierre (2011). Oxygen-Independent Stabilization of the Oxygen-Labile Transcription Factor HIF-1 alpha with Dimethyloxalyl Glycine or FG-4497 Increases Hematopoietic Stem Cell Quiescence In Vivo and Mobilization in Response to G-CSF. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology. |
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2011 Conference Publication Impairment of Hematopoietic Stem Cell (HSC) Niche by G-CSF Is Associated with Rapid Mobilization of Serially Reconstituting HSC and Reduced Competitive Repopulation of Mobilized Bone MarrowLevesque, Jean-Pierre, Barbier, Valerie, Nowlan, Bianca, McCarhty, Domenica and Winkler, Ingrid G. (2011). Impairment of Hematopoietic Stem Cell (HSC) Niche by G-CSF Is Associated with Rapid Mobilization of Serially Reconstituting HSC and Reduced Competitive Repopulation of Mobilized Bone Marrow. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology. |
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2011 Conference Publication Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-LymphopoiesisLevesque, Jean-Pierre, Bendall, Linda J., Pettit, Allison R., Raggatt, Liza, Jacobsen, Rebecca, Barbier, Valarie, Nowlan, Bianca, Shen, Yi Shen, Sims, Natalie A. and Winkler, Ingrid G. (2011). Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-Lymphopoiesis. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology. |
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2010 Conference Publication A molecular profile of the hematopoietic stem cell niche at the endosteumHelwani, F., Winkler, I., Price, G. and Levesque, J. P. (2010). A molecular profile of the hematopoietic stem cell niche at the endosteum. 39th Annual Scientific Meeting of the ISEH - Society for Hematology and Stem Cells, Melbourne, VIC, Australia, 15-18 September 2010. Philadelphia, PA, United States: Elsevier. |
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2010 Conference Publication The role of tissue inhibitor of metalloproteinase-3 (TIMP-3) in hematopoiesisShen, Y., Barbier, V., Winkler, I., Sims, N., Hendy, J. and Levesque, J. P. (2010). The role of tissue inhibitor of metalloproteinase-3 (TIMP-3) in hematopoiesis. 39th Annual Scientific Meeting of the ISEH - Society for Hematology and Stem Cells, Melbourne, VIC, Australia, 15-18 September 2010. Philadelphia, PA, United States: Elsevier. |
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2010 Conference Publication DEPLETION OF BONE MARROW PHAGOCYTES CAUSES THE MOBILIZATION OF LONG-TERM RECONSTITUTING HEMATOPOIETIC STEM CELLSJacobsen, RN, Levesque, JP, Barbier, V, Raggatt, LJ and Pettit, AR (2010). DEPLETION OF BONE MARROW PHAGOCYTES CAUSES THE MOBILIZATION OF LONG-TERM RECONSTITUTING HEMATOPOIETIC STEM CELLS. 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells, Melbourne AUSTRALIA, SEP 15-18, 2010. NEW YORK: ELSEVIER SCIENCE INC. |
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2009 Conference Publication Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances ChemoresistanceWinkler, Ingrid G., Barbier, Valerie, Nowlan, Bianca, Smith, Theodore, Patton, John T., Magnani, John L. and Levesque, Jean-Pierre (2009). Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance. 51st Annual Meeting of the American Society of Hematology, New Orleans, LA, United States, 5-8 December 2009. Washington, DC, United States: American Society of Hematology. |
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2009 Conference Publication Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating bloodLevesque, J. P., Barbier, V., Wadley, R. and Winkler, I. G. (2009). Positioning of mouse bone marrow hematopoietic stem and progenitor cells and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells (HSC) reside in niches that are poorly perfused by circulating blood. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. Philadelphia, PA, United States: Elsevier. |
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2009 Conference Publication Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistanceWinkler, I. G., Levesque, J. P., Barbier, V. and Nowlan, B. (2009). Absence of e-selectin delays hematopoietic stem cell (HSC) turnover and enhances chemoresistance. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. Philadelphia, PA, United States: Elsevier. |
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2009 Conference Publication Endosteal Macrophages Maintain the Hematopoietic Stem Cell (Hsc) Niche and Participate in Hsc Mobilization Induced by G-Csf or ChemotherapyLevesque, J. P., Raggatt, L. J., Pettit, A. R., Sims, N. A., Bendall, L. J. and Helwani, F. (2009). Endosteal Macrophages Maintain the Hematopoietic Stem Cell (Hsc) Niche and Participate in Hsc Mobilization Induced by G-Csf or Chemotherapy. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. NEW YORK: ELSEVIER SCIENCE INC. |
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2009 Conference Publication Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilizationPettit, A. R., Sims, N. A., Winkler, I. G., Alexander, K. A., Helwani, F., Raggatt, L. J. and Levesque, J. P. (2009). Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization. 2nd Joint Meeting of the International Bone and Mineral Society/Australian New Zealand Bone and Mineral Society, Sydney, Australia, 21-25 March, 2009. United States: Elsevier Inc.. doi: 10.1016/j.bone.2009.01.082 |
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2008 Conference Publication The Role of Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) in HematopoiesisShen, Yi, Barbier, Valerie, Winkler, Ingrid G., Hendy, Jean and Levesque, Jean-Pierre (2008). The Role of Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) in Hematopoiesis. 50th Annual Meeting of the American-Society-of-Hematology, San Francisco, CA, United States, 6-9 December 2008. Washington, DC, United States: American Society of Hematology. |
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2008 Conference Publication Endosteal Niches and Lymphopoiesis Are Inhibited during G-CSF-Induced Hematopoietic Stem Cell MobilizationLevesque, Jean-Pierre, Sims, Natalie A., Bendall, Linda J., Shen, Yi and Winkler, Ingrid G. (2008). Endosteal Niches and Lymphopoiesis Are Inhibited during G-CSF-Induced Hematopoietic Stem Cell Mobilization. 50th Annual Meeting of the American-Society-of-Hematology, San Francisco, CA, United States, 6-9 December 2008. Washington, DC, United States: American Society of Hematology. |
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2007 Conference Publication Absence of E-selectin at the vascular niche delays hematopoietic stem cell turn-overWinkler, Ingrid G., Nowlan, Bianca, Barbier, Valerie and Levesque, Jean-Pierre (2007). Absence of E-selectin at the vascular niche delays hematopoietic stem cell turn-over. 49th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA, United States, 8-11 December 2007. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V110.11.609.609 |
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2006 Conference Publication Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY)Levesque, Jean-Pierre, Winkler, Ingrid G., Hendy, Jean and Nilsson, Susan K. (2006). Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY). 48th Annual Meeting of the American Society of Hematology, Orlando, FL United States, 9-12 December 2006. Washington, DC United States: American Society of Hematology. |
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2005 Conference Publication G-CSF potently suppresses osteoblast activity in the bone marrowChristopher, M. J., Liu, F., Short, B., Simmons, P. J., Winkler, I., Levesque, J. P. and Link, D. C. (2005). G-CSF potently suppresses osteoblast activity in the bone marrow. 47th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA, United States, 10-13 December 2005. Washington, DC, United States: American Society of Hematology. |
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2004 Conference Publication Protease-dependent and protease-independent mechanisms of hematopoietic progenitor cell (HPC) mobilizationLevesque, JP, Liu, F, Winkler, IG, Simmons, PJ, Betsuyaku, T, Senior, R, Pham, C and Link, DC (2004). Protease-dependent and protease-independent mechanisms of hematopoietic progenitor cell (HPC) mobilization. 33rd Annual Meeting of the International Society for Experimental Hematology, New Orleans, LA, United States, 17-20 July 2004. Philadelphia, PA, United States: Elsevier. |
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2003 Conference Publication P-selectin delays the in vitro differentiation of murine lin- Sca-1+c-KIT+ cells whereas E-selectin accelerates their differentiationEto, T, Winkler, , Purton, L, Simmons, P and Levesque, JP (2003). P-selectin delays the in vitro differentiation of murine lin- Sca-1+c-KIT+ cells whereas E-selectin accelerates their differentiation. 32nd Annual Scientific Meeting of the International Society for Experimental Hematology, Paris, France, 5-8 July 2003. Philadelphia, PA, United States: Elsevier. |
