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2026

Journal Article

Correction: The cytotoxicity of gomesin peptides is mediated by the glycosphingolipid pathway and lipid-cholesterol interactions

Fernandez-Carrasco, Isabel, Moral-Sanz, Javier, Kurdyukov, Sergey, Obis, Èlia, Hartmann, Lissy Maike, Magalhães Novais, Silvia Carina, Waller, Matthew A., McKinnon, Naomi, Chung, Felicity, Salazar Castejón, Francisco Javier, Rainho, Daniel P., Dekan, Zoltan, Kremsmayr, Thomas, Jandl, Bernhard, Filipič, Kristina Eleršič, Pamplona, Reinald, Jové, Mariona, Fernandez-Rojo, Manuel A., Anderluh, Gregor, Muttenthaler, Markus, Alewood, Paul F. A., Procházka, Jan, Neely, G. Gregory, Deplazes, Evelyne and Ikonomopoulou, Maria P. (2026). Correction: The cytotoxicity of gomesin peptides is mediated by the glycosphingolipid pathway and lipid-cholesterol interactions. Cell Death Discovery, 12 (1) 179. doi: 10.1038/s41420-026-03009-x

Correction: The cytotoxicity of gomesin peptides is mediated by the glycosphingolipid pathway and lipid-cholesterol interactions

2026

Journal Article

Mechanistic Insights from Differences in the Aggregate Morphologies of Amphotericin B and Its Less Toxic Variant Am-2-19 (Turletricin)

Ting-Williams, Luke, Stroet, Martin and Deplazes, Evelyne (2026). Mechanistic Insights from Differences in the Aggregate Morphologies of Amphotericin B and Its Less Toxic Variant Am-2-19 (Turletricin). ACS Medicinal Chemistry Letters, 17 (3) acsmedchemlett.6c00070, 750-756. doi: 10.1021/acsmedchemlett.6c00070

Mechanistic Insights from Differences in the Aggregate Morphologies of Amphotericin B and Its Less Toxic Variant Am-2-19 (Turletricin)

2026

Journal Article

Biophysics meets fungal biology: Characterising the fungal cell envelope and its interactions with drug-like molecules

Obeng-Gyasi, Obed and Deplazes, Evelyne (2026). Biophysics meets fungal biology: Characterising the fungal cell envelope and its interactions with drug-like molecules. Quarterly Reviews of Biophysics, 59 e8, 59. doi: 10.1017/s0033583526100158

Biophysics meets fungal biology: Characterising the fungal cell envelope and its interactions with drug-like molecules

2026

Journal Article

Chasing nature’s anion binders

Li, Junhong, Stroet, Martin, Shang, Vivian G., Lyu, Wenrui, Clegg, Jack K., Deplazes, Evelyne and Wu, Xin (2026). Chasing nature’s anion binders. Chem 103036, 103036. doi: 10.1016/j.chempr.2026.103036

Chasing nature’s anion binders

2025

Journal Article

Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins

Low, Yu Shang, Roche, Solace G., Aleksandrova, Nadezhda A., Foley, Gabriel, Low, Jason K.K., Box, Joseph K., Croll, Tristan I., Chassagnon, Irene R., Lott, J. Shaun, Deplazes, Evelyne, Bodén, Mikael, Hurst, Mark RH, Piper, Sarah J. and Landsberg, Michael J. (2025). Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins. Nature Communications, 16 (1) 11121, 1-13. doi: 10.1038/s41467-025-66050-x

Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins

2025

Journal Article

The cytotoxicity of gomesin peptides is mediated by the glycosphingolipid pathway and lipid-cholesterol interactions

Fernandez-Carrasco, Isabel, Moral-Sanz, Javier, Kurdyukov, Sergey, Monne, Èlia Obis, Hartmann, Lissy Maike, Magalhães Novais, Silvia Carina, Waller, Matthew A., McKinnon, Naomi, Chung, Felicity, Salazar Castejón, Francisco Javier, Rainho, Daniel P., Dekan, Zoltan, Kremsmayr, Thomas, Jandl, Bernhard, Filipič, Kristina Eleršič, Pamplona, Reinald, Jové, Mariona, Fernandez-Rojo, Manuel A., Anderluh, Gregor, Muttenthaler, Markus, Alewood, Paul F. A., Procházka, Jan, Neely, G. Gregory, Deplazes, Evelyne and Ikonomopoulou, Maria P. (2025). The cytotoxicity of gomesin peptides is mediated by the glycosphingolipid pathway and lipid-cholesterol interactions. Cell Death Discovery, 11 (1) 538, 538. doi: 10.1038/s41420-025-02817-x

The cytotoxicity of gomesin peptides is mediated by the glycosphingolipid pathway and lipid-cholesterol interactions

2025

Journal Article

Computational lipidomics reveals environment-specific membrane remodeling in prostate cancer

Hao, Yumeng, Williams-Noonan, Billy J., Sutton, Patrick, Young, Reuben S. E., Blanksby, Stephen J., Deplazes, Evelyne and O’Mara, Megan L. (2025). Computational lipidomics reveals environment-specific membrane remodeling in prostate cancer. Journal of Chemical Information and Modeling, 65 (23) acs.jcim.5c02447, 12894-12904. doi: 10.1021/acs.jcim.5c02447

Computational lipidomics reveals environment-specific membrane remodeling in prostate cancer

2025

Journal Article

Steroids and steroid-like compounds alter the ion permeability of phospholipid bilayers via distinct interactions with lipids and interfacial water

Larder, Morgan, Crowley, Jackson, Hossain, Sheikh I. and Deplazes, Evelyne (2025). Steroids and steroid-like compounds alter the ion permeability of phospholipid bilayers via distinct interactions with lipids and interfacial water. Physical Chemistry Chemical Physics, 27 (4), 2101-2113. doi: 10.1039/d4cp03254c

Steroids and steroid-like compounds alter the ion permeability of phospholipid bilayers via distinct interactions with lipids and interfacial water

2025

Journal Article

The cytotoxicity of gomesin peptides is mediated by the glycosphingolipid pathway and lipid-cholesterol interactions

Fernandez-Carrasco, J., Moral-Sanz, J., Kurdyukov, S., Obis Monne, È., Novais, S. C. M., Ikonomopoulou, M. P. and Deplazes, E. (2025). The cytotoxicity of gomesin peptides is mediated by the glycosphingolipid pathway and lipid-cholesterol interactions. Cell Death and Differentiation.

The cytotoxicity of gomesin peptides is mediated by the glycosphingolipid pathway and lipid-cholesterol interactions

2024

Journal Article

Secondary structure propensities of the Ebola delta peptide E40 in solution and model membrane environments

Li, Jiayu, Eagles, David A., Tucker, Isaac J., Pereira Schmidt, Anneka C. and Deplazes, Evelyne (2024). Secondary structure propensities of the Ebola delta peptide E40 in solution and model membrane environments. Biophysical Chemistry, 314 107318, 1-9. doi: 10.1016/j.bpc.2024.107318

Secondary structure propensities of the Ebola delta peptide E40 in solution and model membrane environments

2024

Journal Article

A charge-neutral organic cage selectively binds strongly hydrated sulfate anions in water

Jing, Liuyang, Deplazes, Evelyne, Clegg, Jack K. and Wu, Xin (2024). A charge-neutral organic cage selectively binds strongly hydrated sulfate anions in water. Nature Chemistry, 16 (3), 1-8. doi: 10.1038/s41557-024-01457-5

A charge-neutral organic cage selectively binds strongly hydrated sulfate anions in water

2024

Journal Article

Hfe permease and Haemophilus influenzae manganese homeostasis

Ganio, Katherine, Nasreen, Marufa, Yang, Zihao, Maunders, Eve A., Luo, Zhenyao, Hossain, Sheikh Imamul, Ngu, Dalton H. Y., Ellis, Daniel, Gu, Jin, Neville, Stephanie L., Wilksch, Jonathan, Gunn, Adam P., Whittall, Jonathan J., Kobe, Boštjan, Deplazes, Evelyne, Kappler, Ulrike and McDevitt, Christopher A. (2024). Hfe permease and Haemophilus influenzae manganese homeostasis. ACS Infectious Diseases, 10 (2), 436-452. doi: 10.1021/acsinfecdis.3c00407

Hfe permease and Haemophilus influenzae manganese homeostasis

2023

Journal Article

Biochemical interactions between the Atm1-like transporter from Novosphingobium aromaticivorans and heavy metals

Rottet, Sarah, Iqbal, Shagufta, Xifaras, Rachel, Singer, Michael T., Scott, Colin, Deplazes, Evelyne and Callaghan, Richard (2023). Biochemical interactions between the Atm1-like transporter from Novosphingobium aromaticivorans and heavy metals. Archives of Biochemistry and Biophysics, 744 109696, 109696. doi: 10.1016/j.abb.2023.109696

Biochemical interactions between the Atm1-like transporter from Novosphingobium aromaticivorans and heavy metals

2023

Journal Article

Influence of force field choice on the conformational landscape of rat and human islet amyloid polypeptide

Moore, Sandra J., Deplazes, Evelyne and Mancera, Ricardo L. (2023). Influence of force field choice on the conformational landscape of rat and human islet amyloid polypeptide. Proteins: Structure, Function, and Bioinformatics, 91 (3), 338-353. doi: 10.1002/prot.26432

Influence of force field choice on the conformational landscape of rat and human islet amyloid polypeptide

2022

Journal Article

The concentration-dependent effect of hydrocortisone on the structure of model lung surfactant monolayer by using an in silico approach

Islam, Mohammad Zohurul, Hossain, Sheikh I., Deplazes, E., Luo, Zhen and Saha, Suvash C. (2022). The concentration-dependent effect of hydrocortisone on the structure of model lung surfactant monolayer by using an in silico approach. RSC Advances, 12 (51), 33313-33328. doi: 10.1039/d2ra05268g

The concentration-dependent effect of hydrocortisone on the structure of model lung surfactant monolayer by using an in silico approach

2022

Journal Article

Vinca alkaloid binding to P-glycoprotein occurs in a processive manner

Iqbal, Shagufta, Flux, Caitlin, Briggs, Deborah A., Deplazes, Evelyne, Long, Jiansi, Skrzypek, Ruth, Rothnie, Alice, Kerr, Ian D. and Callaghan, Richard (2022). Vinca alkaloid binding to P-glycoprotein occurs in a processive manner. Biochimica et Biophysica Acta - Biomembranes, 1864 (10) 184005, 1-10. doi: 10.1016/j.bbamem.2022.184005

Vinca alkaloid binding to P-glycoprotein occurs in a processive manner

2022

Journal Article

The role of ion-lipid interactions and lipid packing in ion-induced pores and transient defects caused by phenolic compounds

Hossain, Sheikh I., Seppelt, Mathilda, Nguyen, Natalie, Stokes, Chelsea and Deplazes, Evelyne (2022). The role of ion-lipid interactions and lipid packing in ion-induced pores and transient defects caused by phenolic compounds. Biophysical Journal, 121 (18), 3520-3532. doi: 10.1016/j.bpj.2022.08.001

The role of ion-lipid interactions and lipid packing in ion-induced pores and transient defects caused by phenolic compounds

2022

Journal Article

Concentration-dependent cortisone adsorption and interaction with model lung surfactant monolayer

Islam, Mohammad Zohurul, Hossain, Sheikh I., Deplazes, Evelyne and Saha, Suvash C. (2022). Concentration-dependent cortisone adsorption and interaction with model lung surfactant monolayer. Molecular Simulation, 48 (18), 1627-1638. doi: 10.1080/08927022.2022.2113397

Concentration-dependent cortisone adsorption and interaction with model lung surfactant monolayer

2022

Journal Article

Structural and biochemical characterization of Acinetobacter baumannii ZnuA

Alquethamy, Saleh, Ganio, Katherine, Luo, Zhenyao, Hossain, Sheikh I., Hayes, Andrew J., Ve, Thomas, Davies, Mark R., Deplazes, Evelyne, Kobe, Boštjan and McDevitt, Christopher A. (2022). Structural and biochemical characterization of Acinetobacter baumannii ZnuA. Journal of Inorganic Biochemistry, 231 111787, 1-11. doi: 10.1016/j.jinorgbio.2022.111787

Structural and biochemical characterization of Acinetobacter baumannii ZnuA

2022

Journal Article

The impact of chromate on Pseudomonas aeruginosa molybdenum homeostasis

Maunders, Eve A., Ngu, Dalton H. Y., Ganio, Katherine, Hossain, Sheikh I., Lim, Bryan Y. J., Leeming, Michael G., Luo, Zhenyao, Tan, Aimee, Deplazes, Evelyne, Kobe, Boštjan and McDevitt, Christopher A. (2022). The impact of chromate on Pseudomonas aeruginosa molybdenum homeostasis. Frontiers in Microbiology, 13 903146, 1-19. doi: 10.3389/fmicb.2022.903146

The impact of chromate on Pseudomonas aeruginosa molybdenum homeostasis