|
2016 Journal Article Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancerHarrington, Brittney S., He, Yaowu, Davies, Claire M., Wallace, Sarah J., Adams, Mark N., Beaven, Elizabeth A., Roche, Deborah K., Kennedy, Catherine, Chetty, Naven P., Crandon, Alexander J., Flatley, Christopher, Oliveira, Niara B., Shannon, Catherine M., deFazio, Anna, Tinker, Anna V., Gilks, C. Blake, Gabrielli, Brian, Brennan, Donal J., Coward, Jermaine I., Armes, Jane E., Perrin, Lewis C. and Hooper, John D. (2016). Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer. British Journal of Cancer, 114 (4), 417-426. doi: 10.1038/bjc.2015.471 |
|
2016 Journal Article New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathwaysHe, Yaowu, Harrington, Brittney S. and Hooper, John D. (2016). New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways. Oncoscience, 3 (1), 5-8. doi: 10.18632/oncoscience.286 |
|
2016 Conference Publication MUC13 protects colorectal cancer cells from death by activating the NF-Kb pathway and is a potential therapeutic targetSheng, Yong H., He, Yaowu, Hasnain, Sumaira Z., Wang, Ran, Tong, Hui, Clarke, Daniel T., Lourie, Rohan, Oancea, Lulia, Wong, Kuanyau, Lumley, John W., Florin, Timothy H., Sutton, Philip, Hooper, John. D., Mcmillan, Nigel A. and Mcguckin, Michael A. (2016). MUC13 protects colorectal cancer cells from death by activating the NF-Kb pathway and is a potential therapeutic target. AACR 107th Annual Meeting on Bioinformatics and Systems Biology, New Orleans, Los Angeles, 16-20 April 2016 . Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2016-3564 |
|
2016 Conference Publication Targeting Apoptosis as a Novel Therapy for Myc-Driven MedulloblastomaJi, Pengxiang, Genovesi, Laura, He, Yaowu, Hooper, John and Wainwright, Brandon (2016). Targeting Apoptosis as a Novel Therapy for Myc-Driven Medulloblastoma. 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), Liverpool England, 12-15 June 2016. United States: Oxford University Press. |
|
2016 Journal Article Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistanceHe, Y., Wu, A. C., Harrington, B. S., Davies, C. M., Wallace, S. J., Adams, M. N., Palmer, J. S., Roche, D. K., Hollier, B. G., Westbrook, T. F., Hamidi, H., Konecny, G. E., Winterhoff, B., Chetty, N. P., Crandon, A. J., Oliveira, N. B., Shannon, C. M., Tinker, A. V., Gilks, C. B., Coward, J. I., Lumley, J. W., Perrin, L. C., Armes, J. E. and Hooper, J. D. (2016). Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance. Oncogene, 35 (4), 468-478. doi: 10.1038/onc.2015.101 |
|
2016 Conference Publication The role of cancer stem cells in colorectal cancer metastasisKemp, M. C., Pummer, J., He, Y., Hooper, J., Reuter, B., Borgovan, T., Zhang, X., Sullivan, R., Maresh, G., Green, H., Del Valle, L., Margolin, D. and Li, L. (2016). The role of cancer stem cells in colorectal cancer metastasis. Southern Regional Meeting of the American Federation for Medical Research (AFMR), New Orleans, LA, United States, Feb 18-20, 2016. London, United Kingdom: BMJ Group. doi: 10.1136/jim-2015-000035.415 |
|
2016 Journal Article Potent small agonists of protease activated receptor 2Yau, Mei-Kwan, Suen, Jacky Y., Xu, Weijun, Lim, Junxian, Liu, Ligong, Adams, Mark N., He, Yaowu, Hooper, John D., Reid, Robert C. and Fairlie, David P. (2016). Potent small agonists of protease activated receptor 2. ACS Medicinal Chemistry Letters, 7 (1), 105-110. doi: 10.1021/acsmedchemlett.5b00429 |
|
2015 Journal Article EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surfaceAdams, M. N., Harrington, B. S., He, Y., Davies, C. M., Wallace, S. J., Chetty, N. P., Crandon, A. J., Oliveira, N. B., Shannon, C. M., Coward, J. I., Lumley, J. W., Perrin, L. C., Armes, J. E. and Hooper, J. D. (2015). EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface. Oncogene, 34 (11), 1375-1383. doi: 10.1038/onc.2014.88 |
|
2015 Conference Publication EGF-induced recycling of the cancer promoting protein CDCP1Adams, Mark N., Harrington, Brittney S., He, Yaowu, Davies, Claire M., Wallace, Sarah J., Chetty, Naven P., Crandon, Alexander J., Oliveira, Niara B., Shannon, Catherine M., Coward, Jermaine I., Lumley, John W., Perrin, Lewis C., Armes, Jane E. and Hooper, John D. (2015). EGF-induced recycling of the cancer promoting protein CDCP1. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3 |
|
2014 Conference Publication Targeting the cell surface protein Cdcp1 in a model of advanced ovarian cancerHarrington, B., Davies, C. M., Wallace, S. J., He, Y., Armes, J. E., Perrin, L. C. and Hooper, J. D. (2014). Targeting the cell surface protein Cdcp1 in a model of advanced ovarian cancer. London, United Kingdom: B M J Group. |
|
2014 Conference Publication A New Marker of Poor Outcome and Potential Therapeutic Target in Ovarian Clear Cell CarcinomaHooper, J., He, Y., Wu, A., Harrington, B., Davies, C., Wallace, S., Gilks, B., Perrin, L. and Armes, J. (2014). A New Marker of Poor Outcome and Potential Therapeutic Target in Ovarian Clear Cell Carcinoma. 15th Biennial Meeting of the International Gynecologic Cancer Society, Melbourne, VIC Australia, 8-11 November 2014. London, United Kingdom: Lippincott Williams and Wilkins. doi: 10.1097/01.IGC.0000457075.08973.89 |
|
2012 Journal Article Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cellsCasar, B., He, Y., Iconomou, M., Hooper, J. D., Quigley, J. P. and Deryugina, E. I. (2012). Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells. Oncogene, 31 (35), 3924-3938. doi: 10.1038/onc.2011.555 |
|
2012 Journal Article The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migrationDong, Ying, He, Yaowu, de Boer, Leonore, Stack, M. Sharon, Lumley, John W., Clements, Judith A. and Hooper, John D. (2012). The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration. Journal of Biological Chemistry, 287 (13), 9792-9803. doi: 10.1074/jbc.M111.335448 |
|
2011 Journal Article Cellular settings mediating Src substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734Wortmann, Andreas, He, Yaowu, Christensen, Melinda E., Linn, Mayla, Lumley, John W., Pollock, Pamela M., Waterhouse, Nigel J. and Hooper, John D. (2011). Cellular settings mediating Src substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734. Journal of Biological Chemistry, 206 (49), 42303-42315. doi: 10.1074/jbc.M111.227462 |
|
2011 Journal Article The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2Adams, Mark N., Christensen, Melinda E., He, Yaowu, Waterhouse, Nigel J. and Hooper, John D. (2011). The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2. PLoS One, 6 (11) e28018, 1-14. doi: 10.1371/journal.pone.0028018 |
|
2010 Journal Article Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKC deltaHe, Yaowu, Wortmann, Andreas, Burke, Les J., Reid, Janet C., Adams, Mark N., Abdul-Jabbar, Ibtissam, Quigley, James P., Leduc, Richard, Kirchhofer, Daniel and Hooper, John D. (2010). Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKC delta. Journal of Biological Chemistry, 285 (34), 26162-26173. doi: 10.1074/jbc.M109.096453 |
|
2009 Journal Article Downstream targets of heterogeneous nuclear ribonucleoprotein A2 mediate cell proliferationHe, Yaowu, Rothnagel, Joseph A., Epis, Michael R., Leedman, Peter J. and Smith, Ross (2009). Downstream targets of heterogeneous nuclear ribonucleoprotein A2 mediate cell proliferation. Molecular Carcinogenesis, 48 (2), 167-179. doi: 10.1002/mc.20467 |
|
2009 Journal Article Nuclear functions of heterogeneous nuclear ribonucleoproteins A/BHe, Yaowu and Smith, Ross (2009). Nuclear functions of heterogeneous nuclear ribonucleoproteins A/B. Cellular and Molecular Life Sciences, 66 (7), 1239-1256. doi: 10.1007/s00018-008-8532-1 |
|
2009 Journal Article The cell surface glycoprotein CDCP1 in cancer - Insights, opportunities, and challengesWortmann, Andreas, He, Yaowu, Deryugina, Elena I., Quigley, James P. and Hooper, John D. (2009). The cell surface glycoprotein CDCP1 in cancer - Insights, opportunities, and challenges. IUBMB Life, 61 (7), 723-730. doi: 10.1002/iub.198 |
|
2008 Journal Article The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channelsHe, Yaowu, Hryciw, Deanne H., Carroll, Melanie L., Myers, Stephen A., Whitbread, Astrid K., Kumar, Sharad, Poronnik, Philip and Hooper, John D. (2008). The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels. Journal of Biological Chemistry, 283 (35), 24000-24010. doi: 10.1074/jbc.M803361200 |
