Overview
Background
Manju Chandrasegaram is a General and Hepato-Pancreato-Biliary (HPB) Surgeon and clinical leader dedicated to advancing care for patients with complex gastrointestinal disease. Her research focuses on pancreatic cancer and the substratification of periampullary cancers into distinct biological and clinical subtypes, with the aim of refining prognosis and personalising treatment strategies.
She leads and supervises clinical research programs in General and HPB surgery, fostering a collaborative research culture that integrates translational science with frontline surgical practice. In addition, she oversees the development and maintenance of a prospective hospital-based colorectal database to support high-quality outcomes research and continuous quality improvement.
Through mentorship of clinicians and students, she champions rigorous clinical research to inform evidence-based practice and improve patient care.
Availability
- Associate Professor Manju Chandrasegaram is:
- Available for supervision
Research impacts
Across her body of work, Associate Professor Manju Chandrasegaram has made a sustained contribution to clinical surgical research in hepatopancreatobiliary and colorectal disease, with publications spanning tumour characterisation, perioperative outcomes and complex case series that appear in peer‑reviewed surgical and oncology journals such as World Journal of Surgical Oncology. Her research has helped clarify pathological features of periampullary cancers and informs clinical decision‑making in pancreatic and colorectal surgery. She actively supervises and mentors clinicians and students in clinical research, helping develop prospective hospital databases and supporting research projects that enhance evidence‑based practice and improve patient care. Her academic leadership fosters research capacity building within surgical teams and shapes emerging investigators in the field.
Works
Search Professor Manju Chandrasegaram’s works on UQ eSpace
2018
Conference Publication
Refractory intra-abdominal actinomycosis secondary to dropped gallstones treated successfully with absolute ethanol – a case report
Maurice, A.P., Dickfos, M., Chandrasegaram, M., Franz, R., Joseph, V. and Brown, N. (2018). Refractory intra-abdominal actinomycosis secondary to dropped gallstones treated successfully with absolute ethanol – a case report. 13th World Congress of the International Hepato-Pancreato-Biliary Association, Geneva, Switzerland, 4-7 September 2018. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.hpb.2018.06.1445
2018
Journal Article
Meckel's diverticulum enteroliths causing small bowel obstruction
Maurice, Andrew P., Dickfos, Marilla, Mousa, Paul, Bhardwaj, Hemant, Godinho, Savio, Iswariah, Harish and Chandrasegaram, Manju (2018). Meckel's diverticulum enteroliths causing small bowel obstruction. ANZ Journal of Surgery, 88 (5), E475-E476. doi: 10.1111/ans.13423
2018
Journal Article
Cholecystoduodenal Stenting: An Option in Complicated Acute Calculous Cholecystitis in the Elderly Comorbid Patient
Bonner, Brady, Brown, Nicholas I., Joseph, Varghese Pynadath and Chandrasegaram, Manju Dashini (2018). Cholecystoduodenal Stenting: An Option in Complicated Acute Calculous Cholecystitis in the Elderly Comorbid Patient. Case Reports in Surgery, 2018, 1609601-6. doi: 10.1155/2018/1609601
2017
Journal Article
Ampullary cancer of intestinal origin and duodenal cancer - A logical clinical and therapeutic subgroup in periampullary cancer
Chandrasegaram, Manju D., Gill, Anthony J., Samra, Jas, Price, Tim, Chen, John, Fawcett, Jonathan and Merrett, Neil D. (2017). Ampullary cancer of intestinal origin and duodenal cancer - A logical clinical and therapeutic subgroup in periampullary cancer. World Journal of Gastrointestinal Oncology, 9 (10), 407-415. doi: 10.4251/wjgo.v9.i10.407
2016
Conference Publication
Periampullary cancers: forming cancer subgroups based on genomic and molecular profiles
Chandrasegaram, M., Price, T., Samra, J., Fawcett, J. and Merrett, N. (2016). Periampullary cancers: forming cancer subgroups based on genomic and molecular profiles. 12th World Congress of the International Hepato-Pancreato-Biliary Association, São Paulo, Brazil, 20–23 April 2016. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.hpb.2016.02.928
2016
Journal Article
Advances in molecular pathology and treatment of periampullary cancers
Chandrasegaram, Manju D., Chen, John W., Price, Timothy J., Zalcberg, John, Sjoquist, Katrin and Merrett, Neil D. (2016). Advances in molecular pathology and treatment of periampullary cancers. Pancreas, 45 (1), 32-39. doi: 10.1097/MPA.0000000000000385
2015
Journal Article
Meta-analysis of radical resection rates and margin assessment in pancreatic cancer
Chandrasegaram, M. D., Goldstein, D., Simes, J., Gebski, V., Kench, J. G., Gill, A. J., Samra, J. S., Merrett, N. D., Richardson, A. J. and Barbour, A. P. (2015). Meta-analysis of radical resection rates and margin assessment in pancreatic cancer. British Journal of Surgery, 102 (12), 1459-1472. doi: 10.1002/bjs.9892
2015
Conference Publication
Oestrogen hormone receptors in focal nodular hyperplasia
Chandrasegaram, Manju D., Shah, Ali, Chen, John W., Ruszkiewicz, Andrew, Astill, David S., England, Georgina, Raju, Ravish S., Neo, Eu Ling, Dolan, Paul M., Tan, Chuan Ping, Brooke-Smith, Mark, Wilson, Tom, Padbury, Robert T. A. and Worthley, Christopher S. (2015). Oestrogen hormone receptors in focal nodular hyperplasia. Oxford, United Kingdom: Elsevier . doi: 10.1111/hpb.12387
2015
Journal Article
Vascular coil erosion into hepaticojejunostomy following hepatic arterial embolisation
Raashed, Soondoos, Chandrasegaram, Manju D., Alsaleh, Khaled, Schlaphoff, Glen and Merrett, Neil D. (2015). Vascular coil erosion into hepaticojejunostomy following hepatic arterial embolisation. BMC Surgery, 15 (1) 51. doi: 10.1186/s12893-015-0039-8
2015
Journal Article
Large retroperitoneal isolated fibrous cyst in absence of preceding trauma or acute pancreatitis
Ahn, Julie, Chandrasegaram, Manju D., Alsaleh, Khaled, Woodham, Benjamin L., Teo, Adrian, Das, Amithaba, Merrett, Neil D. and Apostolou, Christos (2015). Large retroperitoneal isolated fibrous cyst in absence of preceding trauma or acute pancreatitis. BMC Surgery, 15 (1) 25. doi: 10.1186/s12893-015-0016-2
2015
Journal Article
Response to Re: Palliative bypass for small bowel carcinoid with mesenteric mass and vascular encasement
Chandrasegaram, Manju D., Neo, Eu L., Nathan, Anand D., Dolan, Paul M., Tan, Chuan P., Chen, John W. and Worthley, Christopher S. (2015). Response to Re: Palliative bypass for small bowel carcinoid with mesenteric mass and vascular encasement. ANZ Journal of Surgery, 85 (3), 197-198. doi: 10.1111/ans.12979
2015
Journal Article
Distribution and pathological features of pancreatic, ampullary, biliary and duodenal cancers resected with pancreaticoduodenectomy
Chandrasegaram, Manju D., Chiam, Su C., Chen, John W., Khalid, Aisha, Mittinty, Murthy L., Neo, Eu L., Tan, Chuan P., Dolan, Paul M., Brooke-Smith, Mark E., Kanhere, Harsh and Worthley, Chris S. (2015). Distribution and pathological features of pancreatic, ampullary, biliary and duodenal cancers resected with pancreaticoduodenectomy. World Journal of Surgical Oncology, 13 (1) 85. doi: 10.1186/s12957-015-0498-5
2015
Conference Publication
A multicenter, phase II trial of preoperative gemcitabine and nab-paclitaxel for resectable pancreas cancer: The AGITG GAP study
Barbour, Andrew, O'Rourke, Nicholas, Samra, Jaswinder S., Haghighi, Koroush S, Kench, James, Mitchell, Jenna, Pavlakis, Nick, Burge, Matthew E., Fawcett, Jonathan, Gananadha, Sivikumar, Harris, Marion, Aghmesheh, Morteza, Chua, Yu Jo, Joubert, Warren Lance, Chan, Matthew MK, Chandrasegaram, Manju Dashini, Yip, Sonia, Simes, John, Gebski, Val and Goldstein, David (2015). A multicenter, phase II trial of preoperative gemcitabine and nab-paclitaxel for resectable pancreas cancer: The AGITG GAP study. 2015 Gastrointestinal Cancers Symposium, San Francisco, CA, United States, 15–17 January 2015. Alexandria, VA, United States: American Society of Clinical Oncology. doi: 10.1200/jco.2015.33.3_suppl.387
2014
Journal Article
Palliative bypass for small bowel carcinoid with mesenteric mass and vascular encasement
Nathan, Anand D., Chandrasegaram, Manju D., Neo, Eu L., Dolan, Paul M., Tan, Chuan P., Chen, John W. and Worthley, Christopher S. (2014). Palliative bypass for small bowel carcinoid with mesenteric mass and vascular encasement. ANZ Journal of Surgery, 84 (10), 793-794. doi: 10.1111/ans.12333
2014
Conference Publication
Anticoagulation policy after venous resection with a pancreatectomy: a systematic review
Chandrasegaram, Manju D., Eslick, Guy D., Lee, Wayne, Brooke-Smith, Mark E., Padbury, Rob, Worthley, Christopher S., Chen, John W. and Windsor, John A. (2014). Anticoagulation policy after venous resection with a pancreatectomy: a systematic review. Oxford, United Kingdom: Elsevier . doi: 10.1111/hpb.12205
2014
Journal Article
Large gas containing hepatic abscess following transarterial chemoembolization
Warren, Leigh R., Chandrasegaram, Manju D., Neo, Eu L., Dolan, Paul M., Tan, Chuan P., Chen, John W. and Worthley, Christopher S. (2014). Large gas containing hepatic abscess following transarterial chemoembolization. ANZ Journal of Surgery, 84 (7-8), 587-588. doi: 10.1111/ans.12275
2013
Journal Article
KRAS mutation is a local tumour event and not a field change in pancreatobiliary tumours
Chandrasegaram, M., Chen, D. Y., Tan, C. P., Neo, E. L., Dolan, P. M., Chen, J. W., Brooke-Smith, M. E., Cheetham, G., Ruszkiewicz, A. and Worthley, C. S. (2013). KRAS mutation is a local tumour event and not a field change in pancreatobiliary tumours. British Journal of Medicine and Medical Research, 3 (4), 2069-2075. doi: 10.9734/bjmmr/2013/4604
2013
Journal Article
KRAS mutation is a local tumour event and not a field change in pancreatobiliary tumours
Chandrasegaram, M., Chen, D.Y., Tan, C.P., Neo, E.L., Dolan, P.M., Chen, J.W., Brooke-Smith, M.E., Cheetham, G., Ruszkiewicz, A. and Worthley, C.S. (2013). KRAS mutation is a local tumour event and not a field change in pancreatobiliary tumours. British Journal of Medicine and Medical Research, 3 (4), 2069-2075. doi: 10.9734/bjmmr/2013/4604
2013
Journal Article
A case of pancreatic cancer in the setting of autoimmune pancreatitis with nondiagnostic serum markers
Chandrasegaram, Manju D., Chiam, Su C., Nguyen, Nam Q., Ruszkiewicz, Andrew, Chung, Adrian, Neo, Eu L., Chen, John W., Worthley, Christopher S. and Brooke-Smith, Mark E. (2013). A case of pancreatic cancer in the setting of autoimmune pancreatitis with nondiagnostic serum markers. Case Reports in Surgery, 2013, 809023-6. doi: 10.1155/2013/809023
2012
Journal Article
Falciform ligament abscess from left sided portal pyaemia following malignant obstructive cholangitis
Warren, Leigh R., Chandrasegaram, Manju D., Madigan, Daniel J., Dolan, Paul M., Neo, Eu L. and Worthley, Christopher S. (2012). Falciform ligament abscess from left sided portal pyaemia following malignant obstructive cholangitis. World Journal of Surgical Oncology, 10 (1) 278. doi: 10.1186/1477-7819-10-278
Supervision
Availability
- Associate Professor Manju Chandrasegaram is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Available projects
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Multiple projects in General surgery
Several research opportunities which could be tailored to interest and level of learning and commitment.
Larger scale projects such as database set up and research in areas of general surgery would suit someone who wishes to advance knowledge in clinical research or pursue higher degree
Smaller projects also available - such as systematic reviews, surgical sub studies -
Media
Enquiries
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