Overview
Availability
- Dr Marija Kiska is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Marija Kiska’s works on UQ eSpace
2024
Conference Publication
GERMLINEELP1 DEFICIENCY SENSITIZES CEREBELLAR GRANULE NEURON PROGENITORS TO SHH MEDULLOBLASTOMA
Tanveer Ahmad, Shiekh, Garcia-Lopez, Jesus, Li, Yiran, Hadley, Jennifer, Paul, Leena, Gudenas, Brian, Batts, Melissa, Soliman, Taha, Pitre, Aaron, Kojic, Marija, Manz, Frederik, Zindy, Frederique, Jones, Alun, Mayasundari, Anand, Bianski, Brandon, Tinkle, Christopher, Shirinifard, Abbas, Janke, Laura Janke, Lu, Meifen, Onar-Thomas, Arzu, Pfister, Stefan, Gajjar, Amar, Baker, Suzanne, Roussel, Martine, Rankovic, Zoran, Robinson, Giles, Orr, Brent, Wainwright, Brandon, Kutscher, Lena ... Northcott, Paul (2024). GERMLINEELP1 DEFICIENCY SENSITIZES CEREBELLAR GRANULE NEURON PROGENITORS TO SHH MEDULLOBLASTOMA. 29th Annual Meeting and Education Day of the Society-for-Neuro-Oncology (SNO), Houston Tx, Nov 21-24, 2024. CARY: OXFORD UNIV PRESS INC. doi: 10.1093/neuonc/noae165.1283
2024
Conference Publication
Germline ELP1 deficiency sensitizes cerebellar granule neuron progenitors to SHH medulloblastoma
Ahmad, Shiekh Tanveer, Garcia-Lopez, Jesus, Li, Yiran, Gudenas, Brian, Hadley, Jennifer, Paul, Leena, Batts, Melissa, Soliman, Taha, Kojic, Marija, Pitre, Aaron, Manz, Frederik, Zindy, Frederique, Jones, Alun, Mayasundari, Anand, Bianski, Brandon, Tinkle, Christopher, Shirinifard, Abbas, Janke, Laura, Lu, Meifen, Pfister, Stefan M., Gajjar, Amar, Baker, Suzanne J., Roussel, Martine F., Rankovic, Zoran, Waszak, Sebastian M., Robinson, Giles W., Orr, Brent A., Wainwright, Brandon, Kutscher, Lena M. ... Northcott, Paul A. (2024). Germline ELP1 deficiency sensitizes cerebellar granule neuron progenitors to SHH medulloblastoma. International Symposium on Pediatric Neuro-Oncology (ISPNO), Philadelphia, PA, United States, 29 June - 2 July 2024. Cary, NC, United States: Oxford University Press. doi: 10.1093/neuonc/noae064.462
2023
Journal Article
Efficient detection and monitoring of pediatric brain malignancies with liquid biopsy based on patient-specific somatic mutation screening
Kojic, Marija, Maybury, Mellissa K., Waddell, Nicola, Koufariotis, Lambros T., Addala, Venkateswar, Millar, Amanda, Wood, Scott, Pearson, John V., Hansford, Jordan R., Hassall, Tim and Wainwright, Brandon J. (2023). Efficient detection and monitoring of pediatric brain malignancies with liquid biopsy based on patient-specific somatic mutation screening. Neuro-Oncology, 25 (8), 1507-1517. doi: 10.1093/neuonc/noad032
2023
Conference Publication
ELP1 Germline Deficiency Sensitizes The Granule Neuron Lineage To SHH Medulloblastoma And Exposes Novel Therapeutic Vulnerabilities
Garcia-Lopez, Jesus, Ahmad, Shiekh Tanveer, Li, Yiran, Gudenas, Brian, Kojic, Marija, Manz, Friedrik, Jonchere, Barbara, Mayasundari, Anand, Pitre, Aaron, Hadley, Jennifer, Paul, Leena, Batts, Melissa, Pfister, Stefan, Waszak, Sebastian, Bianski, Brandon, Tinkle, Christopher, Orr, Brent, Rankovic, Zoran, Robinson, Giles, Wainwright, Brandon, Kutscher, Lena, Lin, Hong and Northcott, Paul (2023). ELP1 Germline Deficiency Sensitizes The Granule Neuron Lineage To SHH Medulloblastoma And Exposes Novel Therapeutic Vulnerabilities. 2023 Pediatric Neuro-Oncology Research Conference, Washington, DC United States, 22-24 June 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/neuonc/noad073.255
2023
Conference Publication
ELP1 GERMLINE DEFICIENCY SENSITIZES THE GRANULE NEURON LINEAGE TO SHH MEDULLOBLASTOMA AND EXPOSES NOVEL THERAPEUTIC VULNERABILITIES
Garcia-Lopez, Jesus, Ahmad, Shiekh Tanveer, Li, Yiran, Gudenas, Brian, Kojic, Marija, Manz, Friedrik, Jonchere, Barbara, Mayasundari, Anand, Pitre, Aaron, Hadley, Jennifer, Paul, Leena, Batts, Melissa, Pfister, Stefan, Waszak, Sebastian, Bianski, Brandon, Tinkle, Christopher, Orr, Brent, Rankovic, Zoran, Robinson, Giles, Wainwright, Brandon, Kutscher, Lena, Lin, Hong and Northcott, Paul (2023). ELP1 GERMLINE DEFICIENCY SENSITIZES THE GRANULE NEURON LINEAGE TO SHH MEDULLOBLASTOMA AND EXPOSES NOVEL THERAPEUTIC VULNERABILITIES. CARY: OXFORD UNIV PRESS INC.
2023
Journal Article
Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition
Vo, Tuan, Balderson, Brad, Jones, Kahli, Ni, Guiyan, Crawford, Joanna, Millar, Amanda, Tolson, Elissa, Singleton, Matthew, Kojic, Marija, Robertson, Thomas, Walters, Shaun, Mulay, Onkar, Bhuva, Dharmesh D., Davis, Melissa J., Wainwright, Brandon J., Nguyen, Quan and Genovesi, Laura A. (2023). Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition. Genome Medicine, 15 (1) 29, 29. doi: 10.1186/s13073-023-01185-4
2023
Journal Article
A novel ELP1 mutation impairs the function of the Elongator complex and causes a severe neurodevelopmental phenotype
Kojic, Marija, Abbassi, Nour E. H., Lin, Ting-Yu, Jones, Alun, Wakeling, Emma L., Clement, Emma, Nakou, Vasiliki, Singleton, Matthew, Dobosz, Dominika, Kaliakatsos, Marios, Glatt, Sebastian and Wainwright, Brandon J. (2023). A novel ELP1 mutation impairs the function of the Elongator complex and causes a severe neurodevelopmental phenotype. Journal of Human Genetics, 68 (7), 445-453. doi: 10.1038/s10038-023-01135-3
2023
Journal Article
Elongator and the role of its subcomplexes in human diseases
Gaik, Monika, Kojic, Marija, Wainwright, Brandon J and Glatt, Sebastian (2023). Elongator and the role of its subcomplexes in human diseases. EMBO Molecular Medicine, 15 (2) e16418, e16418. doi: 10.15252/emmm.202216418
2022
Journal Article
Functional divergence of the two Elongator subcomplexes during neurodevelopment
Gaik, Monika, Kojic, Marija, Stegeman, Megan R., Öncü‐Öner, Tülay, Kościelniak, Anna, Jones, Alun, Mohamed, Ahmed, Chau, Pak Yan Stefanie, Sharmin, Sazia, Chramiec‐Głąbik, Andrzej, Indyka, Paulina, Rawski, Michał, Biela, Anna, Dobosz, Dominika, Millar, Amanda, Chau, Vann, Ünalp, Aycan, Piper, Michael, Bellingham, Mark C., Eichler, Evan E., Nickerson, Deborah A., Güleryüz, Handan, Abbassi, Nour El Hana, Jazgar, Konrad, Davis, Melissa J., Mercimek‐Andrews, Saadet, Cingöz, Sultan, Wainwright, Brandon J. and Glatt, Sebastian (2022). Functional divergence of the two Elongator subcomplexes during neurodevelopment. EMBO Molecular Medicine, 14 (7) e15608, e15608. doi: 10.15252/emmm.202115608
2021
Journal Article
SOX9 defines distinct populations of cells in SHH medulloblastoma but is not required for Math1-driven tumour formation
Adolphe, Christelle, Millar, Amanda, Kojic, Marija, Barkauskas, Deborah S., Sundstrom, Anders, Swartling, Fredrik J., Hediyeh-zadeh, Soroor, Tan, Chin Wee, Davis, Melissa J., Genovesi, Laura A. and Wainwright, Brandon J. (2021). SOX9 defines distinct populations of cells in SHH medulloblastoma but is not required for Math1-driven tumour formation. Molecular Cancer Research, 19 (11), 1831-1839. doi: 10.1158/1541-7786.mcr-21-0117
2021
Conference Publication
MOMC-5. Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma
Genovesi, Laura, Millar, Amanda, Tolson, Elissa, Singleton, Matthew, Hassall, Emily, Kojic, Marija, Brighi, Caterina, Girald, Emily, Andradas, Clara, Kuchibhotla, Mani, Endersby, Raelene, Gottardo, Nicholas, Bernard, Anne, Adolphe, Christelle, Olson, James, Davis, Melissa and Wainwright, Brandon (2021). MOMC-5. Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma. Society for Neuro-Oncology’s Basic and Translational Omics of Brain Tumors and Their Microenvironment Conference, Virtual, 15 - 16 July 2021. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/noajnl/vdab070.015
2021
Journal Article
Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma
Genovesi, Laura A., Millar, Amanda, Tolson, Elissa, Singleton, Matthew, Hassall, Emily, Kojic, Marija, Brighi, Caterina, Girard, Emily, Andradas, Clara, Kuchibhotla, Mani, Bhuva, Dharmesh D., Endersby, Raelene, Gottardo, Nicholas G., Bernard, Anne, Adolphe, Christelle, Olson, James M., Taylor, Michael D., Davis, Melissa J. and Wainwright, Brandon J. (2021). Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma. Genome Medicine, 13 (1) 103, 103. doi: 10.1186/s13073-021-00920-z
2021
Journal Article
Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype
Kojic, Marija, Gawda, Tomasz, Gaik, Monika, Begg, Alexander, Salerno-Kochan, Anna, Kurniawan, Nyoman D., Jones, Alun, Drożdżyk, Katarzyna, Kościelniak, Anna, Chramiec-Głąbik, Andrzej, Hediyeh-Zadeh, Soroor, Kasherman, Maria, Shim, Woo Jun, Sinniah, Enakshi, Genovesi, Laura A., Abrahamsen, Rannvá K., Fenger, Christina D., Madsen, Camilla G., Cohen, Julie S., Fatemi, Ali, Stark, Zornitza, Lunke, Sebastian, Lee, Joy, Hansen, Jonas K., Boxill, Martin F., Keren, Boris, Marey, Isabelle, Saenz, Margarita S., Brown, Kathleen ... Wainwright, Brandon J. (2021). Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype. Nature Communications, 12 (1) 2678, 2678. doi: 10.1038/s41467-021-22888-5
2020
Journal Article
Patient derived orthotopic xenograft models of Medulloblastoma lack a functional blood brain barrier
Genovesi, Laura A., Puttick, Simon, Millar, Amanda, Kojic, Marija, Ji, Pengxiang, Lagendijk, Anne K., Brighi, Caterina, Bonder, Claudine S, Adolphe, Christelle and Wainwright, Brandon J. (2020). Patient derived orthotopic xenograft models of Medulloblastoma lack a functional blood brain barrier. Neuro-Oncology, 23 (5), 732-742. doi: 10.1093/neuonc/noaa266
2020
Journal Article
Germline elongator mutations in Sonic Hedgehog medulloblastoma
Waszak, Sebastian M., Robinson, Giles W,, Gudenas, Brian L., Smith, Kyle S., Forget, Antoine, Kojic, Marija, Garcia-Lopez, Jesus, Hadley, Jennifer, Hamilton, Kayla V., Indersie, Emilie, Buchhalter, Ivo, Kerssemakers, Jules, Jäger, Natalie, Sharma, Tanvi, Rausch, Tobias, Kool, Marcel, Sturm, Dominik, Jones, David T. W., Vasilyeva, Aksana, Tatevossian, Ruth G., Neale, Geoffrey, Lombard, Bérangère, Loew, Damarys, Nakitandwe, Joy, Rusch, Michael, Bowers, Daniel C., Bendel, Anne, Partap, Sonia, Chintagumpala, Murali ... Pfister, Stefan M. (2020). Germline elongator mutations in Sonic Hedgehog medulloblastoma. Nature, 580 (7803), 396-401. doi: 10.1038/s41586-020-2164-5
2020
Journal Article
MR-guided focused ultrasound increases antibody delivery to nonenhancing high-grade glioma
Brighi, Caterina, Reid, Lee, White, Alison L., Genovesi, Laura A., Kojic, Marija, Millar, Amanda, Bruce, Zara, Day, Bryan W., Rose, Stephen, Whittaker, Andrew K. and Puttick, Simon (2020). MR-guided focused ultrasound increases antibody delivery to nonenhancing high-grade glioma. Neuro-Oncology Advances, 2 (1) vdaa030, 1-12. doi: 10.1093/noajnl/vdaa030
2020
Journal Article
Comparative study of preclinical mouse models of high-grade glioma for nanomedicine research: the importance of reproducing blood-brain barrier heterogeneity
Brighi, Caterina, Reid, Lee, Genovesi, Laura A., Kojic, Marija, Millar, Amanda, Bruce, Zara, White, Alison L., Day, Bryan W., Rose, Stephen, Whittaker, Andrew K. and Puttick, Simon (2020). Comparative study of preclinical mouse models of high-grade glioma for nanomedicine research: the importance of reproducing blood-brain barrier heterogeneity. Theranostics, 10 (14), 6361-6371. doi: 10.7150/thno.46468
2018
Journal Article
Elongator mutation in mice induces neurodegeneration and ataxia-like behavior
Kojic, Marija, Gaik, Monika, Kiska, Bence, Salerno-Kochan, Anna, Hunt, Sarah, Tedoldi, Angelo, Mureev, Sergey, Jones, Alun, Whittle, Belinda, Genovesi, Laura A., Adolphe, Christelle, Brown, Darren L., Stow, Jennifer L., Alexandrov, Kirill, Sah, Pankaj, Glatt, Sebastian and Wainwright, Brandon J. (2018). Elongator mutation in mice induces neurodegeneration and ataxia-like behavior. Nature Communications, 9 (1) 3195, 3195. doi: 10.1038/s41467-018-05765-6
2016
Journal Article
The many faces of elongator in neurodevelopment and disease
Kojic, Marija and Wainwright, Brandon (2016). The many faces of elongator in neurodevelopment and disease. Frontiers in Molecular Neuroscience, 9 (NOV2016) 115, 115. doi: 10.3389/fnmol.2016.00115
2016
Other Outputs
Genetic Regulation of Development and Disorders of the Cerebellum
Kojic, Marija (2016). Genetic Regulation of Development and Disorders of the Cerebellum. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/uql.2016.808
Funding
Current funding
Supervision
Availability
- Dr Marija Kiska is:
- Available for supervision
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