
Overview
Availability
- Dr Norbert Wimmer is:
- Available for supervision
Qualifications
- Doctor of Philosophy of Organic Chemistry, Universität fur Bodenkultur Wien
Works
Search Professor Norbert Wimmer’s works on UQ eSpace
2024
Journal Article
Synthetic access to l-guluronic acid via fluorine-directed C-5 epimerization
See, Nicholas W., Wimmer, Norbert, Zhang, Guoqing, Krenske, Elizabeth H. and Ferro, Vito (2024). Synthetic access to l-guluronic acid via fluorine-directed C-5 epimerization. The Journal of Organic Chemistry, 89 (24), 17941-17949. doi: 10.1021/acs.joc.4c01257
2024
Journal Article
Origins of temperature‐dependent anomeric selectivity in glycosylations with an L‐idose thioglycoside
See, Nicholas W., Roseli, Ras Baizureen, Wimmer, Norbert, Le, Tri T., Krenske, Elizabeth H. and Ferro, Vito (2024). Origins of temperature‐dependent anomeric selectivity in glycosylations with an L‐idose thioglycoside. Chemistry – A European Journal, 30 (52) e202400331, e202400331. doi: 10.1002/chem.202400331
2024
Journal Article
Synthesis of a Deuterated Disaccharide Internal Standard for LC-MS/MS Quantitation of Heparan Sulfate in Biological Samples
Pan, Yuchen, He, Qi Qi, Wimmer, Norbert and Ferro, Vito (2024). Synthesis of a Deuterated Disaccharide Internal Standard for LC-MS/MS Quantitation of Heparan Sulfate in Biological Samples. Carbohydrate Research, 545 109270, 109270. doi: 10.1016/j.carres.2024.109270
2024
Journal Article
Amphiphilic heparinoids as potent antiviral agents against SARS-CoV-2
Chhabra, Mohit, Shanthamurthy, Chethan D., Kumar, Nanjudaswamy Vijendra, Mardhekar, Sandhya, Vishweshwara, Sharath S., Wimmer, Norbert, Modhiran, Naphak, Watterson, Daniel, Amarilla, Alberto A., Cha, Jonathan S., Beckett, James R., De Voss, James J., Kayal, Yasmin, Vlodavsky, Israel, Dorsett, Lauren R., Smith, Raymond A. A., Gandhi, Neha S., Kikkeri, Raghavendra and Ferro, Vito (2024). Amphiphilic heparinoids as potent antiviral agents against SARS-CoV-2. Journal of Medicinal Chemistry, 67 (14), 11885-11916. doi: 10.1021/acs.jmedchem.4c00487
2024
Journal Article
Site-Selective Photobromination of O-Acetylated Carbohydrates in Benzotrifluoride
Zhang, Guoqing, See, Nicholas W., Wimmer, Norbert, Godinez, Michael J., Cameron, Scott A., Furneaux, Richard H. and Ferro, Vito (2024). Site-Selective Photobromination of O-Acetylated Carbohydrates in Benzotrifluoride. Organic Letters, 26 (28), 5956-5960. doi: 10.1021/acs.orglett.4c01898
2023
Journal Article
Synthesis of uronic acid 1‐Azasugars as putative inhibitors of α‐Iduronidase, β‐glucuronidase and heparanase
Doherty, Gareth G., Ler, Geraldine Jia Ming, Wimmer, Norbert, Bernhardt, Paul V., Ashmus, Roger A., Vocadlo, David J., Armstrong, Zach W. B., Davies, Gideon J., Maccarana, Marco, Li, Jin-ping, Kayal, Yasmin and Ferro, Vito (2023). Synthesis of uronic acid 1‐Azasugars as putative inhibitors of α‐Iduronidase, β‐glucuronidase and heparanase. ChemBioChem, 24 (4) e202200619, 1-7. doi: 10.1002/cbic.202200619
2022
Journal Article
Synthesis of a Gal-β-(1→4)-Gal disaccharide as a ligand for the fimbrial adhesin UcaD
Boittier, Eric D., Wimmer, Norbert, Harris, Alexandria K., Schembri, Mark A. and Ferro, Vito (2022). Synthesis of a Gal-β-(1→4)-Gal disaccharide as a ligand for the fimbrial adhesin UcaD. Australian Journal of Chemistry, 76 (1), 30-36. doi: 10.1071/ch22158
2021
Journal Article
Development of improved synthetic routes to pixatimod (PG545), a sulfated oligosaccharide-steroid conjugate
Chhabra, Mohit, Wimmer, Norbert, He, Qi Qi and Ferro, Vito (2021). Development of improved synthetic routes to pixatimod (PG545), a sulfated oligosaccharide-steroid conjugate. Bioconjugate Chemistry, 32 (11) acs.bioconjchem.1c00453, 2420-2431. doi: 10.1021/acs.bioconjchem.1c00453
2021
Journal Article
A substituent‐directed strategy for the selective synthesis of L‐hexoses: an expeditious route to L‐idose
See, Nicholas W., Wimmer, Norbert, Krenske, Elizabeth H. and Ferro, Vito (2021). A substituent‐directed strategy for the selective synthesis of L‐hexoses: an expeditious route to L‐idose. European Journal of Organic Chemistry, 2021 (10), 1575-1584. doi: 10.1002/ejoc.202100042
2020
Journal Article
Structural insights into heparanase activity using a fluorogenic heparan sulfate disaccharide
Wu, Liang, Wimmer, Norbert, Davies, Gideon J. and Ferro, Vito (2020). Structural insights into heparanase activity using a fluorogenic heparan sulfate disaccharide. Chemical Communications, 56 (89), 13780-13783. doi: 10.1039/d0cc05932c
2019
Journal Article
Dual targeting of dengue virus virions and NS1 protein with the heparan sulfate mimic PG545
Modhiran, Naphak, Gandhi, Neha S., Wimmer, Norbert, Cheung, Stacey, Stacey, Katryn, Young, Paul R., Ferro, Vito and Watterson, Daniel (2019). Dual targeting of dengue virus virions and NS1 protein with the heparan sulfate mimic PG545. Antiviral Research, 168, 121-127. doi: 10.1016/j.antiviral.2019.05.004
2015
Journal Article
Investigations into the decomposition of aminoacyl-substituted monosaccharide scaffolds from a drug discovery library
He, Q. Q., Wimmer, N., Verquin, G., Meutermans, W. and Ferro, V. (2015). Investigations into the decomposition of aminoacyl-substituted monosaccharide scaffolds from a drug discovery library. Organic and Biomolecular Chemistry, 13 (13), 4070-4079. doi: 10.1039/C5OB00122F
2012
Journal Article
Discovery of PG545: A highly potent and simultaneous inhibitor of angiogenesis, tumor growth, and metastasis
Ferro, Vito, Liu, Ligong, Johnstone, Ken D., Wimmer, Norbert, Karoli, Tomislav, Handley, Paul, Rowley, Jessica, Dredge, Keith, Li, Cai Ping, Hammond, Edward, Davis, Kat, Sarimaa, Laura, Harenberg, Job and Bytheway, Ian (2012). Discovery of PG545: A highly potent and simultaneous inhibitor of angiogenesis, tumor growth, and metastasis. Journal of Medicinal Chemistry, 55 (8), 3804-3813. doi: 10.1021/jm201708h
2012
Journal Article
Lipopeptides for the fragment-based pharmaceutics design
Ziora, Zyta M., Wimmer, Norbert, New, Roger, Skwarczynski, Mariusz and Toth, Istvan (2012). Lipopeptides for the fragment-based pharmaceutics design. International Journal of Organic Chemistry, 2 (01), 75-81. doi: 10.4236/ijoc.2012.21013
2011
Journal Article
Synthesis of glycolipopeptidic building blocks for carbohydrate receptor discovery
Ziora, Zyta M., Wimmer, Norbert, New, Roger, Skwarczynski, Mariusz and Toth, Istvan (2011). Synthesis of glycolipopeptidic building blocks for carbohydrate receptor discovery. Carbohydrate Research, 346 (12), 1439-1444. doi: 10.1016/j.carres.2011.03.019
2010
Journal Article
Biological diversity from a structurally diverse library: Systematically scanning conformational space using a pyranose scaffold
Abbenante, Giovanni, Becker, Bernd, Blanc, Sebastien, Clark, Chris, Condie, Glenn, Fraser, Graeme, Grathwohl, Matthias, Halliday, Judy, Henderson, Senka, Lam, Ann, Liu, Ligong, Mann, Maretta, Muldoon, Craig, Pearson, Andrew, Premraj, Rajaratnam, Ramsdale, Tracie, Rossetti, Tony, Schafer, Karl, Le Thanh, Giang, Tometzki, Gerald, Vari, Frank, Verquin, Geraldine, Waanders, Jennifer, West, Michael, Wimmer, Norbert, Yau, Annika, Zuegg, Johannes and Meutermans, Wim (2010). Biological diversity from a structurally diverse library: Systematically scanning conformational space using a pyranose scaffold. Journal of Medicinal Chemistry, 53 (15), 5576-5586. doi: 10.1021/jm1002777
2010
Journal Article
ChemInform Abstract: Synthesis of Neoglycoproteins Containing L-glycero-α-D-manno- Heptopyranosyl-(1→4)- and -(1→5)-linked 3-Deoxy-α- D-manno-oct-2-ulopyranosylonic Acid (Kdo) Phosphate Determinants
Sekljic, H. , Wimmer, N., Hofinger, A., Brade, H. and Kosma, P. (2010). ChemInform Abstract: Synthesis of Neoglycoproteins Containing L-glycero-α-D-manno- Heptopyranosyl-(1→4)- and -(1→5)-linked 3-Deoxy-α- D-manno-oct-2-ulopyranosylonic Acid (Kdo) Phosphate Determinants. ChemInform, 28 (45), no-no. doi: 10.1002/chin.199745240
2010
Journal Article
Lipophile-conjugated sulfated oligosaccharides as novel microbicides against HIV-1
Said, J, Trybala, E, Andersson, E, Johnstone, K, Liu, LG, Wimmer, N, Ferro, V and Bergstrom, T (2010). Lipophile-conjugated sulfated oligosaccharides as novel microbicides against HIV-1. Antiviral Research, 86 (3), 286-295. doi: 10.1016/j.antiviral.2010.03.011
2010
Journal Article
The PG500 series: Novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy
Dredge, K., Hammond, E., Davis, K., Li, C. P., Liu, L., Johnstone, K., Handley, P., Wimmer, N., Gonda, T. J., Gautam, A., Ferro, V. and Bytheway, I. (2010). The PG500 series: Novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy. Investigational New Drugs, 28 (3), 276-283. doi: 10.1007/s10637-009-9245-5
2010
Journal Article
Orthogonally Protected Monosaccharide Building Blocks for Solid Phase Production of Diversity Oriented Libraries
Rajaratnam, Premraj, Gupta, Praveer, Katavic, Peter, Kuipers, Krystle, Huyh, Ngoc, Ryan, Sarah, Falzun, Tania, Tometzki, Gerrald B., Bornaghi, Laurent, Le Thanh, Giang, Abbenante, Giovanni, Liu, Ligong, Meutermans, Wim, Wimmer, Norbert and West, Michael L. (2010). Orthogonally Protected Monosaccharide Building Blocks for Solid Phase Production of Diversity Oriented Libraries. Australian Journal of Chemistry, 63 (4), 693-699. doi: 10.1071/CH09480
Supervision
Availability
- Dr Norbert Wimmer is:
- Available for supervision
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Supervision history
Completed supervision
-
2021
Doctor Philosophy
Synthesis of novel inhibitors of heparan sulfate-binding proteins
Associate Advisor
Other advisors: Professor Lisbeth Grondahl, Professor Vito Ferro
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