Overview
Availability
- Dr Mohammad Zafar Imam is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Mohammad Zafar Imam’s works on UQ eSpace
2024
Journal Article
J-2156, a small molecule somatostatin type 4 receptor agonist, alleviated hindpaw hypersensitivity in the streptozotocin-induced rat model of painful diabetic neuropathy but with a 2-fold decrease in potency at an advanced stage in the model, mimicking morphine
Kuo, A., Imam, M. Z., Li, R., Lin, L., Raboczyj, A., Bohmer, A. E., Nicholson, J. R., Corradini, L. and Smith, M. T. (2024). J-2156, a small molecule somatostatin type 4 receptor agonist, alleviated hindpaw hypersensitivity in the streptozotocin-induced rat model of painful diabetic neuropathy but with a 2-fold decrease in potency at an advanced stage in the model, mimicking morphine. Frontiers in Pharmacology, 15 1346801. doi: 10.3389/fphar.2024.1346801
2024
Book Chapter
Side Effects of Central Analgesic Drugs
Imam, M. Z., Kuo, A. and Smith, M. T. (2024). Side Effects of Central Analgesic Drugs. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays. (pp. 735-758) Cham: Springer International Publishing. doi: 10.1007/978-3-031-35529-5_70
2023
Journal Article
In Vitro Assessment of the Metabolic Stability of Two Novel Endomorphin-2 Analogs, CYX-5 and CYX-6, in Rat Liver Microsomes
Imam, Mohammad Zafar, Ghassabian, Sussan, Kuo, Andy, Cai, Yunxin, Qin, Yajuan, Li, Tingyou and Smith, Maree T. (2023). In Vitro Assessment of the Metabolic Stability of Two Novel Endomorphin-2 Analogs, CYX-5 and CYX-6, in Rat Liver Microsomes. European Journal of Drug Metabolism and Pharmacokinetics, 48 (4), 463-466. doi: 10.1007/s13318-023-00828-6
2023
Journal Article
Multitargeted opioid ligand discovery as a strategy to retain analgesia and reduce opioid-related adverse effects
Smith, Maree T., Kong, Dehui, Kuo, Andy, Imam, Mohammad Z. and Williams, Craig M. (2023). Multitargeted opioid ligand discovery as a strategy to retain analgesia and reduce opioid-related adverse effects. Journal of Medicinal Chemistry, 66 (6), 3746-3784. doi: 10.1021/acs.jmedchem.2c01695
2023
Journal Article
CYX-5, a G-protein biassed MOP receptor agonist, DOP receptor antagonist and KOP receptor agonist, evokes constipation but not respiratory depression relative to morphine in rats
Imam, Mohammad Zafar, Kuo, Andy, Ghassabian, Sussan, Cai, Yunxin, Qin, Yajuan, Li, Tingyou and Smith, Maree T. (2023). CYX-5, a G-protein biassed MOP receptor agonist, DOP receptor antagonist and KOP receptor agonist, evokes constipation but not respiratory depression relative to morphine in rats. Pharmacological Reports, 75 (3), 634-646. doi: 10.1007/s43440-023-00446-8
2022
Journal Article
Analgesic opioid ligand discovery based on nonmorphinan scaffolds derived from natural sources
Smith, Maree T., Kong, Dehui, Kuo, Andy, Imam, Mohammad Z. and Williams, Craig M. (2022). Analgesic opioid ligand discovery based on nonmorphinan scaffolds derived from natural sources. Journal of Medicinal Chemistry, 65 (3) acs.jmedchem.0c01915, 1612-1661. doi: 10.1021/acs.jmedchem.0c01915
2022
Book Chapter
Side effects of central analgesic drugs
Imam, M. Z., Kuo, A. and Smith, M. T. (2022). Side effects of central analgesic drugs. Drug discovery and evaluation: safety and pharmacokinetic assays. (pp. 1-24) Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-030-73317-9_70-1
2020
Journal Article
Assessment of the anti-allodynic efficacy of a glycine transporter 2 inhibitor relative to pregabalin and duloxetine in a rat model of prostate cancer-induced bone pain
Imam, Mohammad Zafar, Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2020). Assessment of the anti-allodynic efficacy of a glycine transporter 2 inhibitor relative to pregabalin and duloxetine in a rat model of prostate cancer-induced bone pain. Pharmacological Reports, 72 (5), 1418-1425. doi: 10.1007/s43440-020-00145-8
2020
Journal Article
Intracerebroventricular administration of CYX-6, a potent μ-opioid receptor agonist, a δ- and κ-opioid receptor antagonist and a biased ligand at μ, δ & κ-opioid receptors, evokes antinociception with minimal constipation and respiratory depression in rats in contrast to morphine
Imam, Mohammad Zafar, Kuo, Andy, Ghassabian, Sussan, Cai, Yunxin, Qin, Yajuan, Li, Tingyou and Smith, Maree T. (2020). Intracerebroventricular administration of CYX-6, a potent μ-opioid receptor agonist, a δ- and κ-opioid receptor antagonist and a biased ligand at μ, δ & κ-opioid receptors, evokes antinociception with minimal constipation and respiratory depression in rats in contrast to morphine. European Journal of Pharmacology, 871 172918, 172918. doi: 10.1016/j.ejphar.2020.172918
2020
Journal Article
Countering opioid-induced respiratory depression by non-opioids that are respiratory stimulants
Imam, Mohammad Zafar, Kuo, Andy and Smith, Maree T. (2020). Countering opioid-induced respiratory depression by non-opioids that are respiratory stimulants. F1000Research, 9 91, 91. doi: 10.12688/f1000research.21738.1
2019
Other Outputs
Analgesic efficacy of novel opioid compounds relative to adverse effects in rats
Imam, Mohammad Zafar (2019). Analgesic efficacy of novel opioid compounds relative to adverse effects in rats. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/uql.2019.625
2018
Journal Article
Trichosanthes dioica Roxb.: a vegetable with diverse pharmacological properties
Khandaker, Mahia, Akter, Saleha and Imam, Mohammad Zafar (2018). Trichosanthes dioica Roxb.: a vegetable with diverse pharmacological properties. Food Science and Human Wellness, 7 (1), 34-48. doi: 10.1016/j.fshw.2017.12.005
2017
Journal Article
Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression
Imam, Mohammad Zafar, Kuo, Andy, Ghassabian, Sussan and Smith, Maree T. (2017). Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression. Neuropharmacology, 131, 238-255. doi: 10.1016/j.neuropharm.2017.12.032
2017
Journal Article
Antinociceptive activity of methanol extract of leaves of Solanum sisymbriifolium in heat and chemical-induced pain
Nasrin, Tania, Khandaker, Mahia, Akter, Saleha and Imam, Mohammad Zafar (2017). Antinociceptive activity of methanol extract of leaves of Solanum sisymbriifolium in heat and chemical-induced pain. Journal of Applied Pharmaceutical Science, 7 (11), 142-146. doi: 10.7324/JAPS.2017.71121
2015
Journal Article
Antinociceptive and neuropharmacological activities of methanol extract of Phoenix sylvestris fruit pulp
Shajib, Md. Shafiullah, Akter, Saleha, Ahmed, Tajnin and Imam, Mohammad Zafar (2015). Antinociceptive and neuropharmacological activities of methanol extract of Phoenix sylvestris fruit pulp. Frontiers in Pharmacology, 6 (OCT) 212, 1-12. doi: 10.3389/fphar.2015.00212
2015
Journal Article
Antinociceptive effect of methanol extract of leaves of Persicaria hydropiper in mice
Khatun, Ambia, Imam, Mohammad Zafar and Rana, Md Sohel (2015). Antinociceptive effect of methanol extract of leaves of Persicaria hydropiper in mice. BMC Complementary and Alternative Medicine, 15 (1) 63, 63. doi: 10.1186/s12906-015-0558-y
2015
Journal Article
Evaluation of antinociceptive activity of ethanol extract of leaves of Adenanthera pavonina
Moniruzzaman, Md., Khatun, Ambia and Imam, Mohammad Zafar (2015). Evaluation of antinociceptive activity of ethanol extract of leaves of Adenanthera pavonina. Evidence-Based Complementary and Alternative Medicine, 2015 412497, 1-8. doi: 10.1155/2015/412497
2014
Journal Article
Evaluation of antinociceptive effect of methanolic extract of leaves of Crataeva nurvala Buch.-Ham.
Moniruzzaman, Md and Imam, Mohammad Zafar (2014). Evaluation of antinociceptive effect of methanolic extract of leaves of Crataeva nurvala Buch.-Ham.. BMC Complementary and Alternative Medicine, 14 (1) 354, 1-7. doi: 10.1186/1472-6882-14-354
2014
Journal Article
Antinociceptive effect of ethanol extract of leaves of Lannea coromandelica
Imam, Mohammad Zafar and Moniruzzaman, Md (2014). Antinociceptive effect of ethanol extract of leaves of Lannea coromandelica. Journal of Ethnopharmacology, 154 (1), 109-115. doi: 10.1016/j.jep.2014.03.032
2014
Journal Article
Evaluation of antinociceptive activity of hydromethanol extract of Cyperus rotundus in mice
Imam, Mohammad Zafar and Sumi, Chandra Datta (2014). Evaluation of antinociceptive activity of hydromethanol extract of Cyperus rotundus in mice. BMC Complementary and Alternative Medicine, 14 83. doi: 10.1186/1472-6882-14-83
Supervision
Availability
- Dr Mohammad Zafar Imam is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Discovery and Pharmacological Evaluation of Novel Analgesics for the Relief of Ross River Virus Induced Chronic Pain
Associate Advisor
Other advisors: Professor Kate Schroder, Dr Andy Kuo, Emeritus Professor Maree Smith
Media
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