Overview
Availability
- Honorary Professor Grant Ramm is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Grant Ramm’s works on UQ eSpace
2024
Journal Article
A maternal high-fat diet predisposes to infant lung disease via increased neutrophil-mediated IL-6 trans-signaling
Curren, Bodie, Ahmed, Tufael, Rashid, Ridwan B., Sebina, Ismail, Al Amin Sikder, Md., Howard, Daniel R., Alorro, Mariah, Ullah, Md. Ashik, Bissell, Alec, Rahman, Muhammed Mahfuzur, Pearen, Michael A., Ramm, Grant A., Varelias, Antiopi, Rose-John, Stefan, MacDonald, Kelli P. A., Hoelzle, Robert, Ó Cuív, Páraic, Spann, Kirsten M., Dennis, Paul G. and Phipps, Simon (2024). A maternal high-fat diet predisposes to infant lung disease via increased neutrophil-mediated IL-6 trans-signaling. Cell Reports, 43 (11) 114974, 114974. doi: 10.1016/j.celrep.2024.114974
2024
Journal Article
Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis
Sajiir, Haressh, Wong, Kuan Yau, Müller, Alexandra, Keshvari, Sahar, Burr, Lucy, Aiello, Elena, Mezza, Teresa, Giaccari, Andrea, Sebastiani, Guido, Dotta, Francesco, Ramm, Grant A., Macdonald, Graeme A., McGuckin, Michael A., Prins, Johannes B. and Hasnain, Sumaira Z. (2024). Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis. Nature Communications, 15 (1) 4527, 1-12. doi: 10.1038/s41467-024-48320-2
2024
Journal Article
Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis
Sajiir, Haressh, Keshvari, Sahar, Wong, Kuan Yau, Borg, Danielle J., Steyn, Frederik J., Fercher, Christian, Taylor, Karin, Taylor, Breten, Barnard, Ross T., Müller, Alexandra, Moniruzzaman, Md, Miller, Gregory, Wang, Ran, Fotheringham, Amelia, Schreiber, Veronika, Sheng, Yong Hua, Hancock, Janelle Louise, Loo, Dorothy, Burr, Lucy, Huynh, Tony, Lockett, Jack, Ramm, Grant A., Macdonald, Graeme A., Prins, Johannes B., McGuckin, Michael A. and Hasnain, Sumaira Z. (2024). Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis. Nature Communications, 15 (1) 4528, 4528. doi: 10.1038/s41467-024-48317-x
2024
Journal Article
The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation
Fernandez-Rojo, Manuel A., Pearen, Michael A., Burgess, Anita G., Ikonomopoulou, Maria P., Hoang-Le, Diem, Genz, Berit, Saggiomo, Silvia L., Nawaratna, Sujeevi S. K., Poli, Maura, Reissmann, Regina, Gobert, Geoffrey N., Deutsch, Urban, Engelhardt, Britta, Brooks, Andrew J., Jones, Alun, Arosio, Paolo and Ramm, Grant A. (2024). The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation. Science Signaling, 17 (830) eade4335, 1-16. doi: 10.1126/scisignal.ade4335
2024
Journal Article
Extrahepatic iron loading associates with the propensity to develop advanced hepatic fibrosis in hemochromatosis
Olynyk, John K., St. Pierre, Timothy G., Chen, James, Frazer, David M., Ramm, Louise E. and Ramm, Grant A. (2024). Extrahepatic iron loading associates with the propensity to develop advanced hepatic fibrosis in hemochromatosis. Gastro Hep Advances, 3 (4), 454-460. doi: 10.1016/j.gastha.2024.01.011
2023
Journal Article
The ancestral haplotype markers HLA -A3 and B7 do not influence the likelihood of advanced hepatic fibrosis or cirrhosis in HFE hemochromatosis
Olynyk, John K., Grainger, Richard, Currie, Helen, Ramm, Louise E. and Ramm, Grant A. (2023). The ancestral haplotype markers HLA -A3 and B7 do not influence the likelihood of advanced hepatic fibrosis or cirrhosis in HFE hemochromatosis. Scientific Reports, 13 (1) 7775, 1-6. doi: 10.1038/s41598-023-35028-4
2023
Journal Article
Exploring the impact of severity in hepatic fibrosis disease on the intrahepatic distribution of novel biodegradable nanoparticles targeted towards different disease biomarkers
Balaji, Arunpandian, Bell, Craig A., Houston, Zachary H., Bridle, Kim R., Genz, Berit, Fletcher, Nicholas L., Ramm, Grant A. and Thurecht, Kristofer J. (2023). Exploring the impact of severity in hepatic fibrosis disease on the intrahepatic distribution of novel biodegradable nanoparticles targeted towards different disease biomarkers. Biomaterials, 302 122318, 1-18. doi: 10.1016/j.biomaterials.2023.122318
2023
Journal Article
Risk factors for more rapid progression of severe liver fibrosis in children with cystic fibrosis-related liver disease: A multi-center study validated by liver biopsy
Sakhuja, Shruti, Staples, Heather M., Minard, Charles G., Ramm, Louise E., Lewindon, Peter J., Ramm, Grant A. and Leung, Daniel H. (2023). Risk factors for more rapid progression of severe liver fibrosis in children with cystic fibrosis-related liver disease: A multi-center study validated by liver biopsy. Liver International, 43 (6), 1277-1286. doi: 10.1111/liv.15572
2023
Journal Article
Clinical practice guidelines on hemochromatosis: Asian Pacific Association for the Study of the Liver
Crawford, Darrell H. G., Ramm, Grant A., Bridle, Kim R., Nicoll, Amanda J., Delatycki, Martin B. and Olynyk, John K. (2023). Clinical practice guidelines on hemochromatosis: Asian Pacific Association for the Study of the Liver. Hepatology International, 17 (3), 522-541. doi: 10.1007/s12072-023-10510-3
2023
Journal Article
TWEAK/Fn14 Signalling Regulates the Tissue Microenvironment in Chronic Pancreatitis
Abu Bakar, N. Dianah B., Carlessi, Rodrigo, Gogoi-Tiwari, Jully, Köhn-Gaone, Julia, Williams, Vincent, Falasca, Marco, Olynyk, John K., Ramm, Grant A. and Tirnitz-Parker, Janina E. E. (2023). TWEAK/Fn14 Signalling Regulates the Tissue Microenvironment in Chronic Pancreatitis. Cancers, 15 (6) 1807, 1-15. doi: 10.3390/cancers15061807
2022
Journal Article
Building a case for pancreas and liver targeted intereukin-22 therapy in fatty liver disease
Sajiir, Haressh, Wong, Kuan Yau, Mueller, Alexandra, Keshvari, Sahar, Wang, Ran, Wiid, Percival, Ramm, Grant, Macdonald, Graeme, Prins, John, McGuckin, Michael and Hasnain, Sumaira (2022). Building a case for pancreas and liver targeted intereukin-22 therapy in fatty liver disease. Journal of Hepatology, 77 (Supplement 1), S190-S191. doi: 10.1016/s0168-8278(22)00756-5
2022
Journal Article
Synthetic peptides derived from the Schistosoma mansoni secretory protein Sm16 induce contrasting responses in hepatic stellate cells
Carson, Jack P., Robinson, Mark W., Ramm, Grant A. and Gobert, Geoffrey N. (2022). Synthetic peptides derived from the Schistosoma mansoni secretory protein Sm16 induce contrasting responses in hepatic stellate cells. Experimental Parasitology, 236-237 108255, 108255. doi: 10.1016/j.exppara.2022.108255
2022
Journal Article
Gamma-glutamyl transpeptidase-to-platelet ratio as a biomarker of liver disease and hepatic fibrosis severity in paediatric Cystic Fibrosis
Calvopina, Diego A., Lewindon, Peter J., Ramm, Louise E., Noble, Charlton, Hartel, Gunter F., Leung, Daniel H and Ramm, Grant A. (2022). Gamma-glutamyl transpeptidase-to-platelet ratio as a biomarker of liver disease and hepatic fibrosis severity in paediatric Cystic Fibrosis. Journal of Cystic Fibrosis, 21 (2), 236-242. doi: 10.1016/j.jcf.2021.10.014
2022
Journal Article
Advanced but not mild liver disease is a predictor of decreased survival in children with cystic fibrosis, with far greater impact in females: a 27-year real-life cohort study
Baldissera, Marilisa, Lewindon, Peter J., Ramm, Louise E., Hartel, Gunter F., Mattiello, Rita and Ramm, Grant A. (2022). Advanced but not mild liver disease is a predictor of decreased survival in children with cystic fibrosis, with far greater impact in females: a 27-year real-life cohort study. Journal of Cystic Fibrosis, 21 (2), 230-235. doi: 10.1016/j.jcf.2021.11.015
2022
Journal Article
Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease
Keshvari, Sahar, Genz, Berit, Teakle, Ngari, Caruso, Melanie, Cestari, Michelle F., Patkar, Omkar L., Tse, Brian W. C., Sokolowski, Kamil A., Ebersbach, Hilmar, Jascur, Julia, MacDonald, Kelli P. A., Miller, Gregory, Ramm, Grant A., Pettit, Allison R., Clouston, Andrew D., Powell, Elizabeth E., Hume, David A. and Irvine, Katharine M. (2022). Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease. Disease Models and Mechanisms, 15 (4) dmm049387, 1-15. doi: 10.1242/dmm.049387
2022
Journal Article
Arthritis Prediction of Advanced Hepatic Fibrosis in HFE Hemochromatosis
Andersson, Lauren, Powell, Lawrie W., Ramm, Louise E., Ramm, Grant A. and Olynyk, John K. (2022). Arthritis Prediction of Advanced Hepatic Fibrosis in HFE Hemochromatosis. Mayo Clinic Proceedings, 97 (9), 1649-1655. doi: 10.1016/j.mayocp.2022.02.017
2021
Journal Article
Risk of Liver Cancer in HFE-Hemochromatosis
Olynyk, John K. and Ramm, Grant A. (2021). Risk of Liver Cancer in HFE-Hemochromatosis. Gastroenterology, 161 (5), 1718-1719. doi: 10.1053/j.gastro.2021.08.025
2021
Journal Article
RNA sequencing of LX-2 cells treated with TGF-β1 identifies genes associated with hepatic stellate cell activation
Carson, Jack P., Robinson, Mark W., Ramm, Grant A. and Gobert, Geoffrey N. (2021). RNA sequencing of LX-2 cells treated with TGF-β1 identifies genes associated with hepatic stellate cell activation. Molecular Biology Reports, 48 (12), 7677-7688. doi: 10.1007/s11033-021-06774-3
2021
Journal Article
Cost-effectiveness of a serum biomarker test for risk-stratified liver ultrasound screening for hepatocellular carcinoma
Carter, Hannah E., Jeffrey, Gary P., Ramm, Grant A. and Gordon, Louisa G. (2021). Cost-effectiveness of a serum biomarker test for risk-stratified liver ultrasound screening for hepatocellular carcinoma. Value in Health, 24 (10), 1454-1462. doi: 10.1016/j.jval.2021.04.1286
2021
Journal Article
The role of sonic hedgehog in human holoprosencephaly and short-rib polydactyly syndromes
Loo, Christine K. C., Pearen, Michael A. and Ramm, Grant A. (2021). The role of sonic hedgehog in human holoprosencephaly and short-rib polydactyly syndromes. International Journal of Molecular Sciences, 22 (18) 9854, 9854. doi: 10.3390/ijms22189854
Funding
Past funding
Supervision
Availability
- Honorary Professor Grant Ramm is:
- Available for supervision
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Supervision history
Completed supervision
-
2019
Doctor Philosophy
Non-invasive assessment of paediatric cystic fibrosis liver disease and the role of microRNAs in disease mechanism
Principal Advisor
-
2019
Doctor Philosophy
Investigating the potential of circulating microRNAs as non-invasive biomarkers in cirrhosis and hepatocellular carcinoma
Principal Advisor
-
2013
Doctor Philosophy
Clinical and Molecular Modifiers of the Progression of Liver Fibrosis in HFE-Associated Haemochromatosis
Principal Advisor
-
2021
Doctor Philosophy
Development and evaluation of novel ligand-targeted bioreducible gene-carrier systems in type 2 diabetes
Associate Advisor
Other advisors: Dr Rakesh Naduvile Veedu, Dr Harendra Parekh
-
2016
Doctor Philosophy
Development and delivery of novel modified siRNA-based therapeutics against type 2 diabetes
Associate Advisor
Other advisors: Dr Rakesh Naduvile Veedu, Dr Harendra Parekh
-
2013
Doctor Philosophy
Roles of oxidative DNA damage, and reactive oxygen and nitrogen species in the evolution of human hepatocellular carcinoma
Associate Advisor
Other advisors: Associate Professor Graeme Macdonald
-
2010
Doctor Philosophy
Transcriptomics of Schistosoma japonicum-induced immunopathology
Associate Advisor
Other advisors: Professor Malcolm Jones
-
2005
Doctor Philosophy
IRON OVERLOAD IN END-STAGE LIVER DISEASE: MECHANISMS AND PATHOPHYSIOLOGICAL SIGNIFICANCE
Associate Advisor
Other advisors: Professor Darrell Crawford
Media
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