Overview
Availability
- Dr Murugan Kalimutho is:
- Available for supervision
Works
Search Professor Murugan Kalimutho’s works on UQ eSpace
2018
Journal Article
LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer
Boulding, T., McCuaig, R. D., Tan, A., Hardy, K., Wu, F., Dunn, J., Kalimutho, M., Sutton, C. R., Forwood, J. K., Bert, A. G., Goodall, G. J., Malik, L., Yip, D., Dahlstrom, J. E., Zafar, A., Khanna, K. K. and Rao, S. (2018). LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer. Scientific Reports, 8 (1) 73. doi: 10.1038/s41598-017-17913-x
2017
Conference Publication
Synergistic inhibition of CEP55 induces mitotic catastrophe and specifically targets aggressive breast cancer
Sinha, D., Kalimutho, M., Lopez, A. J. and Khanna, K. K. (2017). Synergistic inhibition of CEP55 induces mitotic catastrophe and specifically targets aggressive breast cancer. 42nd European-Society-for-Medical-Oncology Congress (ESMO), Madrid, Spain, 8-12 September 2017. Oxford, United Kingdom: OXFORD UNIV.
2017
Conference Publication
Targeting thioredoxin reductase 1 in novel combination therapies in p53 mutant triple negative breast cancer
Raninga, P., Kalimutho, M., Sinha, D., Bain, A., Tonissen, K. and Khanna, K. K. (2017). Targeting thioredoxin reductase 1 in novel combination therapies in p53 mutant triple negative breast cancer. 42nd European Society for Medical Oncology Congress (ESMO), Madrid, Spain, 8-12 September 2017. Oxford, United Kingdom: Oxford University Press.
2017
Conference Publication
Dual inhibition of MEK1/2 and PLK1 specifically targets aggressive breast cancer cell population with CEP55 elevated expression
Sinha, Debottam, Kalimutho, Murugan, Lopez, J. Alejandro and Khanna, Kum Kum (2017). Dual inhibition of MEK1/2 and PLK1 specifically targets aggressive breast cancer cell population with CEP55 elevated expression. Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC , United States, 1-5 April 2017. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2017-1144
2017
Journal Article
Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae
Kalimutho, Murugan, Bain, Amanda L., Mukherjee, Bipasha, Nag, Purba, Nanayakkara, Devathri M., Harten, Sarah K., Harris, Janelle L., Subramanian, Goutham N., Sinha, Debottam, Shirasawa, Senji, Srihari, Sriganesh, Burma, Sandeep and Khanna, Kum Kum (2017). Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae. Molecular Oncology, 11 (5), 470-490. doi: 10.1002/1878-0261.12040
2017
Journal Article
FBXO31 protects against genomic instability by capping FOXM1 levels at the G2/M transition
Jeffery, J. M., Kalimutho, M., Johansson, P., Cardenas, D. G., Kumar, R. and Khanna, K. K. (2017). FBXO31 protects against genomic instability by capping FOXM1 levels at the G2/M transition. Oncogene, 36 (7), 1012-1022. doi: 10.1038/onc.2016.268
2017
Journal Article
The metastasis suppressor RARRES3 as an endogenous inhibitor of the immunoproteasome expression in breast cancer cells
Anderson, Alison M., Kalimutho, Murugan, Harten, Sarah, Nanayakkara, Devathri M., Khanna, Kum Kum and Ragan, Mark A. (2017). The metastasis suppressor RARRES3 as an endogenous inhibitor of the immunoproteasome expression in breast cancer cells. Scientific Reports, 7 (1) 39873. doi: 10.1038/srep39873
2017
Conference Publication
Abstract PR04: Wnt and MAPK pathway activation in conventional and serrated colorectal neoplasia
Whitehall, Vicki, Borowsky, Jennifer, Bond, Catherine, Bettington, Mark, Pearson, Sally-Ann, Kalimutho, Murugan, Liu, John, Dumenil, Troy, McKeone, Diane, Jamieson, Saara, Fernando, Winnie, Fennell, Lochlan, Clouston, Andrew, Rosty, Christophe, Brown, Ian, Walker, Neal and Leggett, Barbara (2017). Abstract PR04: Wnt and MAPK pathway activation in conventional and serrated colorectal neoplasia. AACR Special Conference: Colorectal Cancer: From Initiation to Outcomes, Tampa, FL, United States, 17-20 September 2016. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.crc16-pr04
2016
Journal Article
RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis
Bond, Catherine E., McKeone, Diane M., Kalimutho, Murugan, Bettington, Mark L., Pearson, Sally-Ann, Dumenil, Troy D., Wockner, Leesa F., Burge, Matthew, Leggett, Barbara A. and Whitehall, Vicki L. J. (2016). RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis. Oncotarget, 7 (43), 70589-70600. doi: 10.18632/oncotarget.12130
2016
Journal Article
Adenosine 2B receptor expression on cancer cells promotes metastasis
Mittal, Deepak, Sinha, Debottam, Barkauskas, Deborah, Young, Arabella, Kalimutho, Murugan, Stannard, Kimberley, Caramia, Franco, Haibe-Kains, Benjamin, Stagg, John, Khanna, Kum Kum, Loi, Sherene and Smyth, Mark J. (2016). Adenosine 2B receptor expression on cancer cells promotes metastasis. Cancer Research, 76 (15), 4372-4382. doi: 10.1158/0008-5472.CAN-16-0544
2016
Journal Article
Understanding the functional impact of copy number alterations in breast cancer using a network modeling approach
Srihari, Sriganesh, Kalimutho, Murugan, Lal, Samir, Singla, Jitin, Patel, Dhaval, Simpson, Peter T., Khanna, Kum Kum and Ragan, Mark A. (2016). Understanding the functional impact of copy number alterations in breast cancer using a network modeling approach. Molecular Biosystems, 12 (3), 963-972. doi: 10.1039/C5MB00655D
2016
Journal Article
Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer
French, Juliet D., Johnatty, Sharon E., Lu, Yi, Beesley, Jonathan, Gao, Bo, Kalimutho, Murugan, Henderson, Michelle J., Russell, Amanda J., Kar, Siddhartha, Chen, Xiaoging, Hillman, Kristine M., Kaufmann, S, Sivakumaran H., O'Reilly, Martin, Wang, Chen, Korbie, Darren J., Lambrechts, Diether, Despierre, Evelyn, Van Nieuwenhuysen, Els, Lambrechts, Sandra, Vergote, Ignace, Karlan, Beth, Lester, Jenny, Orsulic, Sandra, Walsh, Christine, Fasching, Peter A., Beckmann, Matthias W., Ekici, Arif B., Hein, Alexander ... MacGregor, Stuart (2016). Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer. Oncotarget, 7 (6), 6353-6368. doi: 10.18632/oncotarget.7047
2015
Journal Article
Targeted Therapies for Triple-Negative Breast Cancer: Combating a Stubborn Disease
Kalimutho, Murugan, Parsons, Kate, Mittal, Deepak, Lopez, J.Alejandro, Srihari, Sriganesh and Khanna, Kum Kum (2015). Targeted Therapies for Triple-Negative Breast Cancer: Combating a Stubborn Disease. Trends in Pharmacological Sciences, 36 (12), 822-846. doi: 10.1016/j.tips.2015.08.009
2015
Journal Article
Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesis
Jeffery, J., Sinha, D., Srihari, S., Kalimutho, M. and Khanna, K. K. (2015). Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesis. Oncogene, 35 (6), 683-690. doi: 10.1038/onc.2015.128
2015
Conference Publication
Effects of the porcupine inhibitor, LGK974, on RNF43 mutant and wild type colorectal cancer cell lines
Bond, C., Kalimutho, M., Bettington, M., Pearson, S., Leggett, B. and Whitehall, V. (2015). Effects of the porcupine inhibitor, LGK974, on RNF43 mutant and wild type colorectal cancer cell lines. Abstracts of Gastro 2015 GESA‐AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, QLD, Australia, 28 September‐2 October 2015. Richmond, VIC, Australia: John Wiley & Sons.
2014
Journal Article
Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma
de Andrade, Lucas Ferrari, Ngiow, Shin F., Stannard, Kimberly, Rusakiewicz, Sylvie, Kalimutho, Murugan, Khanna, Kum Kum, Tey, Siok-Keen, Takeda, Kazyuoshi, Zitvogel, Laurence, Martinet, Ludovic and Smyth, Mark J. (2014). Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma. Cancer Research, 74 (24), 7298-7308. doi: 10.1158/0008-5472.CAN-14-1339
2014
Journal Article
ADAM17-Dependent c-MET-STAT3 Signaling Mediates Resistance to MEK Inhibitors in KRAS Mutant Colorectal Cancer
Van Schaeybroeck, Sandra, Kalimutho, Murugan, Dunne, Philip D., Carson, Robbie, Allen, Wendy, Jithesh, Puthen V., Redmond, Keara L., Sasazuki, Takehiko, Shirasawa, Senji, Blayney, Jaine, Michieli, Paolo, Fenning, Cathy, Lenz, Heinz-Josef, Lawler, Mark, Longley, Daniel B. and Johnston, Patrick G. (2014). ADAM17-Dependent c-MET-STAT3 Signaling Mediates Resistance to MEK Inhibitors in KRAS Mutant Colorectal Cancer. Cell Reports, 7 (6), 1940-1955. doi: 10.1016/j.celrep.2014.05.032
2014
Journal Article
Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma
Al-Ejeh, Fares, Pajic, Marina, Shi, Wei, Kalimutho, Murugan, Miranda, Mariska, Nagrial, Adnan M., Chou, Angela, Biankin, Andrew V., Grimmond, Sean M., Brown, Michael P. and Khanna, Kum Kum (2014). Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma. Clinical Cancer Research, 20 (12), 3187-3197. doi: 10.1158/1078-0432.CCR-14-0048
2014
Journal Article
Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer
Al-Ejeh, F., Simpson, P. T., Sanus, J. M., Klein, K., Kalimutho, M., Shi, W., Miranda, M., Kutasovic, J., Raghavendra, A., Madore, J., Reid, L., Krause, L., Chenevix-Trench, G., Lakhani, S. R. and Khanna, K. K. (2014). Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer. Oncogenesis, 3 (4) e100, 1-12. doi: 10.1038/oncsis.2014.14
2014
Journal Article
AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer
Dunne, Philip D., McArt, Darragh G., Blayney, Jaine K., Kalimutho, Murugan, Greer, Samanda, Wang, Tingting, Srivastava, Supriya, Ong, Chee Wee, Arthur, Ken, Loughrey, Maurice, Redmond, Keara, Longley, Daniel B., Salto-Tellez, Manuel, Johnston, Patrick G. and Van Schaeybroeck, Sandra (2014). AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer. Clinical Cancer Research, 20 (1), 164-175. doi: 10.1158/1078-0432.CCR-13-1354
Funding
Current funding
Supervision
Availability
- Dr Murugan Kalimutho is:
- Available for supervision
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