Overview
Background
Professor Craig Munns is the Mayne Professor of Paediatrics and Director of the Child Health Research Centre, The University of Queensland. Professor Munns is also a Senior Medical Officer in Paediatric Endocrinology and Diabetes at Queensland Children’s Hospital. He graduated from The University of Queensland, before training in paediatrics and endocrinology at The Royal Children’s Hospital, Brisbane. Professor Munns completed his PhD in paediatric growth disorders through UQ. He then undertook a post-doctoral fellowship in paediatric genetic bone disorders at The Shriners Hospital for Children, Montreal, Canada. From 2004 to 2021, Prof Munns was Senior Staff Specialist in Genetic and Metabolic Bone Disorders and Paediatric Endocrinologist at The Children’s Hospital at Westmead, Sydney. He also undertook roles as Clinical Program Director, Division of Diagnostic Services and Clinical Trials Lead at Kids Research. As Clinical Trials Lead his focus was on developing a research-intensive health system and introducing advanced therapeutics.
Professor Munns is an international expert in paediatric musculoskeletal disorders. His primary clinical and research interests are in diagnosis and management of primary and secondary bone disorders, including osteogenesis imperfecta, hypophosphataemic rickets, disuse osteoporosis and nutritional rickets. He has undertaken a wide range of investigator initiated and sponsored clinical trials, authored international consensus documents and has supervised numerous PhD and Masters students. Prof Munns is actively involved in national and international scientific societies. He was treasurer of Asia Pacific Paediatric Endocrine Society, is the inaugural treasurer of the International Society of Children’s Bone Health and has chaired the program organising committees Australasian Paediatric Endocrine Group, Australian and New Zealand Bone and Mineral Society and International Conference of Children’s Bone Health.
Availability
- Professor Craig Munns is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Faculty of Medicine, The University of Queensland
- Doctor of Philosophy of Paediatrics and Reproductive Medicine, The University of Queensland
- Fellow, Royal Australasian College of Physicians, Royal Australasian College of Physicians
Research interests
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Paediatric Musculoskeletal Disorders
Primary and secondary osteoporosis; Genetic rickets (X-linked hypophosphataemia); Nutritional rickets; Focal bone tumours (Giant cell granuloma, Aneurismal bone cysts); Early detection of disease; Bone density assessment
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Clinical Trials
Investigator initiated; Pharmaceutical sponsored; Gene therapy
Research impacts
Professor Munns has developed international consensus guidelines on the prevention and treatment of nutritional rickets. These guidelines have the potential to irradicate this potentially devastating, fully preventable childhood disorder. He has also developed numerous clinical guidelines for the management of paediatric bone disorders such as osteoporosis, X-linked hypophosphataemia, giant cell granuloma and aneurismal bone cysts.
Works
Search Professor Craig Munns’s works on UQ eSpace
2020
Journal Article
Pretreatment with pamidronate decreases bone formation but increases callus bone volume in a rat closed fracture model
Morse, Alyson, McDonald, Michelle M., Mikulec, Kathy, Schindeler, Aaron, Munns, Craig F. and Little, David G. (2020). Pretreatment with pamidronate decreases bone formation but increases callus bone volume in a rat closed fracture model. Calcified Tissue International, 106 (2), 172-179. doi: 10.1007/s00223-019-00615-z
2020
Journal Article
P450 oxidoreductase deficiency: a systematic review and meta-analysis of genotypes, phenotypes, and their relationships
Dean, Benjamin, Chrisp, Georgina L., Quartararo, Maria, Maguire, Ann M., Hameed, Shihab, King, Bruce R., Munns, Craig F., Torpy, David J., Falhammar, Henrik and Rushworth, R. Louise (2020). P450 oxidoreductase deficiency: a systematic review and meta-analysis of genotypes, phenotypes, and their relationships. Journal of Clinical Endocrinology and Metabolism, 105 (3) dgz255, e43-e54. doi: 10.1210/clinem/dgz255
2020
Journal Article
Safety and effectiveness of stoss therapy in children with vitamin D deficiency
Tannous, Paul, Fiscaletti, Melissa, Wood, Nicholas, Gunasekera, Hasantha, Zurynski, Yvonne, Biggin, Andrew, Kilo, Tatjana, Hayes, Evan and Munns, Craig (2020). Safety and effectiveness of stoss therapy in children with vitamin D deficiency. Journal of Paediatrics and Child Health, 56 (1), 81-89. doi: 10.1111/jpc.14497
2019
Journal Article
Targeting adeno-associated virus vectors for local delivery to fractures and systemic delivery to the skeleton
Lee, Lucinda R., Peacock, Lauren, Lisowski, Leszek, Little, David G., Munns, Craig F. and Schindeler, Aaron (2019). Targeting adeno-associated virus vectors for local delivery to fractures and systemic delivery to the skeleton. Molecular Therapy - Methods and Clinical Development, 15, 101-111. doi: 10.1016/j.omtm.2019.08.010
2019
Journal Article
A brief history of nutritional rickets
Wheeler, Benjamin J., Snoddy, Anne Marie E., Munns, Craig, Simm, Peter, Siafarikas, Aris and Jefferies, Craig (2019). A brief history of nutritional rickets. Frontiers in Endocrinology, 10 795. doi: 10.3389/fendo.2019.00795
2019
Journal Article
Burosumab versus conventional therapy in children with X-linked hypophosphataemia: a randomised, active-controlled, open-label, phase 3 trial
Imel, E.A., Glorieux, F.H., Whyte, M.P., Munns, C.F., Ward, L.M., Nilsson, O., Simmons, J.H., Padidela, R., Namba, N., Cheong, H.I. , Pitukcheewanont, P., Sochett, E., Hogler, W., Muroya, K., Tanaka, H., Gottesman, G.S., Biggin, A., Perwad, F., Mao, M., Chen, C.Y., Skrinar, A., San Martin, J. and Portale, A.A. (2019). Burosumab versus conventional therapy in children with X-linked hypophosphataemia: a randomised, active-controlled, open-label, phase 3 trial. Yearbook of Paediatric Endocrinology. doi: 10.1530/ey.16.5.8
2019
Journal Article
Abnormal cortical and trabecular bone in youth with type 1 diabetes and celiac disease
Pham-Short, Anna, Donaghue, Kim C., Ambler, Geoffrey, Briody, Julie, Garnett, Sarah, Munns, Craig F. and Craig, Maria E. (2019). Abnormal cortical and trabecular bone in youth with type 1 diabetes and celiac disease. Diabetes Care, 42 (8), 1489-1495. doi: 10.2337/dc18-2376
2019
Journal Article
FGF23, hypophosphatemia, and emerging treatments
Imel, Erik A., Biggin, Andrew, Schindeler, Aaron and Munns, Craig F. (2019). FGF23, hypophosphatemia, and emerging treatments. JBMR Plus, 3 (8) e10190. doi: 10.1002/jbm4.10190
2019
Conference Publication
Serum 25-hydroxyvitamin D requirements to prevent rickets in Nigerian children on a calcium-deprived diet
Thacher, Tom, Sempos, Christopher, Durazo-Arvizu, Ramon, Munns, Craig, Fischer, Philip and Pettifor, John (2019). Serum 25-hydroxyvitamin D requirements to prevent rickets in Nigerian children on a calcium-deprived diet. 9th International Conference on Children's Bone Health, Salzburg, Austria, 22 - 25 June 2019. Bristol, United Kingdom: Bioscientifica. doi: 10.1530/boneabs.7.p170
2019
Conference Publication
The validity of serum alkaline phosphatase to identify nutritional rickets in Nigerian children on a calcium-deprived diet
Thacher, Tom, Sempos, Christopher, Durazo-Arvizu, Ramon, Munns, Craig, Fischer, Philip and Pettifor, John (2019). The validity of serum alkaline phosphatase to identify nutritional rickets in Nigerian children on a calcium-deprived diet. 9th International Conference on Children's Bone Health, Salzburg, Austria, 22 - 25 June 2019. Bristol, United Kingdom: Bioscientifica. doi: 10.1530/boneabs.7.p58
2019
Journal Article
Burosumab versus conventional therapy in children with X-linked hypophosphataemia: a randomised, active-controlled, open-label, phase 3 trial
Imel, Erik A, Glorieux, Francis H, Whyte, Michael P, Munns, Craig F, Ward, Leanne M, Nilsson, Ola, Simmons, Jill H, Padidela, Raja, Namba, Noriyuki, Cheong, Hae Il, Pitukcheewanont, Pisit, Sochett, Etienne, Högler, Wolfgang, Muroya, Koji, Tanaka, Hiroyuki, Gottesman, Gary S, Biggin, Andrew, Perwad, Farzana, Mao, Meng, Chen, Chao-Yin, Skrinar, Alison, San Martin, Javier and Portale, Anthony A (2019). Burosumab versus conventional therapy in children with X-linked hypophosphataemia: a randomised, active-controlled, open-label, phase 3 trial. The Lancet, 393 (10189), 2416-2427. doi: 10.1016/s0140-6736(19)30654-3
2019
Journal Article
Skeletal and extraskeletal actions of vitamin D: Current evidence and outstanding questions
Bouillon, Roger, Marcocci, Claudio, Carmeliet, Geert, Bikle, Daniel, White, John H., Dawson-Hughes, Bess, Lips, Paul, Munns, Craig F., Lazaretti-Castro, Marise, Giustina, Andrea and Bilezikian, John (2019). Skeletal and extraskeletal actions of vitamin D: Current evidence and outstanding questions. Endocrine Reviews, 40 (4), 1109-1151. doi: 10.1210/er.2018-00126
2019
Journal Article
Bone marrow transplantation for treatment of the Col1a2+/G610C osteogenesis imperfecta mouse model
Lee, Lucinda R., Peacock, Lauren, Ginn, Samantha L., Cantrill, Laurence C., Cheng, Tegan L., Little, David G., Munns, Craig F. and Schindeler, Aaron (2019). Bone marrow transplantation for treatment of the Col1a2+/G610C osteogenesis imperfecta mouse model. Calcified Tissue International, 104 (4), 426-436. doi: 10.1007/s00223-018-0504-3
2019
Journal Article
Long-term outcomes of adolescent anorexia nervosa on bone
Mumford, Jessica, Kohn, Michael, Briody, Julie, Miskovic-Wheatley, Jane, Madden, Sloane, Clarke, Simon, Biggin, Andrew, Schindeler, Aaron and Munns, Craig (2019). Long-term outcomes of adolescent anorexia nervosa on bone. Journal of Adolescent Health, 64 (3), 305-310. doi: 10.1016/j.jadohealth.2018.07.025
2019
Journal Article
A comparison of subtraction MRI with the standard contrast-enhanced imaging in Perthes’ disease
Jamil, K., Walker, T., Onikul, E., Munns, C. F. and Little, D. G. (2019). A comparison of subtraction MRI with the standard contrast-enhanced imaging in Perthes’ disease. Journal of Children's Orthopaedics, 13 (1), 82-88. doi: 10.1302/1863-2548.13.180136
2019
Journal Article
Differential diagnosis of perinatal hypophosphatasia: radiologic perspectives
Offiah, Amaka C., Vockley, Jerry, Munns, Craig F. and Murotsuki, Jun (2019). Differential diagnosis of perinatal hypophosphatasia: radiologic perspectives. Pediatric Radiology, 49 (1), 3-22. doi: 10.1007/s00247-018-4239-0
2018
Journal Article
Variations in the management of acute illness in children with congenital adrenal hyperplasia: An audit of three paediatric hospitals
Chrisp, Georgina L., Maguire, Ann M., Quartararo, Maria, Falhammar, Henrik, King, Bruce R., Munns, Craig F., Torpy, David J., Hameed, Shihab and Rushworth, R. Louise (2018). Variations in the management of acute illness in children with congenital adrenal hyperplasia: An audit of three paediatric hospitals. Clinical Endocrinology, 89 (5), 577-585. doi: 10.1111/cen.13826
2018
Journal Article
Management of endocrine disease: Therapeutics of Vitamin D
Ebeling, P. R., Adler, R. A., Jones, G., Liberman, U. A., Mazziotti, G., Minisola, S., Munns, C. F., Napoli, N., Pittas, A. G., Giustina, A., Bilezikian, J. P. and Rizzoli, R. (2018). Management of endocrine disease: Therapeutics of Vitamin D. European Journal of Endocrinology, 179 (5), R239-R259. doi: 10.1530/EJE-18-0151
2018
Journal Article
Diagnosis of recurrent fracture in a pediatric cohort
Fiscaletti, M., Coorey, C. P., Biggin, A., Briody, J., Little, D. G., Schindeler, A. and Munns, C. F. (2018). Diagnosis of recurrent fracture in a pediatric cohort. Calcified Tissue International, 103 (5), 529-539. doi: 10.1007/s00223-018-0449-6
2018
Journal Article
Vitamin D assays and the definition of hypovitaminosis D: results from the First International Conference on Controversies in Vitamin D
Sempos, Christopher T., Heijboer, Annemieke C., Bikle, Daniel D., Bollerslev, Jens, Bouillon, Roger, Brannon, Patsy M., DeLuca, Hector F., Jones, Glenville, Munns, Craig F., Bilezikian, John P., Giustina, Andrea and Binkley, Neil (2018). Vitamin D assays and the definition of hypovitaminosis D: results from the First International Conference on Controversies in Vitamin D. British Journal of Clinical Pharmacology, 84 (10), 2194-2207. doi: 10.1111/bcp.13652
Funding
Current funding
Supervision
Availability
- Professor Craig Munns is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Tele-Dialysis in community settings: Is it feasible, safe and effective?
Principal Advisor
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Doctor Philosophy
Urinary stem cells for diagnosis and characterisation of primary bone disorders
Principal Advisor
Other advisors: Professor Di Yu
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Doctor Philosophy
Food Allergy Diagnosis and Management in Late Adolescence
Associate Advisor
Other advisors: Associate Professor Jennifer Koplin
Media
Enquiries
Contact Professor Craig Munns directly for media enquiries about:
- Paediatric Bone
- Rickets
- Vitamin D
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