Overview
Background
Dr Yuao Wu is a Research Fellow specializing in nanotechnology, nanosensors, and theranostic medicine. He obtained his PhD in Biomedical Engineering from the Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland (UQ) in 2021 , after completing a Master of Biotechnology at UQ in 2016. His research expertise lies in nanotechnology-enabled molecular bioanalysis, single-particle detection, and the deep molecular profiling of extracellular vesicles (EVs). He has established a strong academic track record in advancing diagnostic nanotechnologies, having published over 30 peer-reviewed papers that have attracted more than 1,200 citations(h-index 20). Actively engaged in national scientific leadership, he serves as the Secretary of the Australian Society of Molecular Imaging (ASMI). Alongside his research, he provides continuous academic mentoring to his research group and co-supervises multiple PhD students developing nanotechnological strategies to detect and treat cardiovascular and inflammatory diseases.
Expertise:
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Nanomaterial Engineering: Surface engineering and functionalization of nanoparticles and liposomes.
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Advanced Analysis & Imaging: High-resolution single-particle analysis and advanced fluorescence imaging.
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Translational Disease Models: Complex in vitro cell culture (including 3D models) and in vivo preclinical models for cardiovascular and inflammatory diseases.
Availability
- Dr Yuao Wu is:
- Available for supervision
Qualifications
- Bachelor of Biomolecular Science, Griffith University
- Masters (Coursework) of Biotechnology, The University of Queensland
- Doctor of Philosophy of Biomedical Engineering, The University of Queensland
Research interests
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Extracellular vesicles (EVs)
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Nanosensors
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Anti-ROS
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Cardiovascular disease
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Theranostics
Research impacts
Dr Wu's research bridges the gap between fundamental nanotechnology and real-world medical applications, aiming to alleviate the global health burden of chronic inflammatory conditions, cardiovascular diseases, and neurodegenerative disorders. By developing highly sensitive, single-particle analytical platforms and targeted nanomedicines, his work provides crucial tools for the early detection and understanding of diseases like atherosclerosis and Alzheimer's.
The impacts of Dr Wu's research activities include:
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Clinical Translation: Developing highly sensitive diagnostic platforms and targeted nanomedicines to accelerate the journey from laboratory bench to real-world medical applications.
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Global Scientific Influence: Published 30+ peer-reviewed papers with over 1,200 citations (h-index 20), demonstrating widespread international adoption of his technical solutions.
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National Leadership: Driving cross-institutional collaboration and knowledge exchange across Australia as the Secretary of the Australian Society of Molecular Imaging (ASMI).
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Next-Generation Mentorship: Training future translational scientists through the active supervision of PhD and master's students.
Works
Search Professor Yuao Wu’s works on UQ eSpace
2026
Journal Article
Nanobiosensors and Artificial Intelligence Strategies for Glycan Profiling in Cancer Progression: A Critical Review
Khamis, Ramlah, Wu, Yuao, Sina, Abu Ali Ibn, Trau, Matt and Wuethrich, Alain (2026). Nanobiosensors and Artificial Intelligence Strategies for Glycan Profiling in Cancer Progression: A Critical Review. ACS Sensors acssensors.5c04911. doi: 10.1021/acssensors.5c04911
2026
Journal Article
miRNAs in cardiovascular disease and an update on emerging trend in electrochemical biosensors for miRNA detection
HalvaeiKhanekahdani, Peyman, Wu, Yuao and Ta, Hang Thu (2026). miRNAs in cardiovascular disease and an update on emerging trend in electrochemical biosensors for miRNA detection. Critical Reviews in Biotechnology, 46 (2), 269-296. doi: 10.1080/07388551.2025.2584689
2025
Journal Article
Assessing the therapeutic potential of a panel of novel VCAM-1 antibodies using microfluidic and three-dimensional in vitro models of vascular inflammation
Pickett, Jessica R., Zacchi, Lucia F., Perera, Binura, Wu, Yuao and Ta, Hang Thu (2025). Assessing the therapeutic potential of a panel of novel VCAM-1 antibodies using microfluidic and three-dimensional in vitro models of vascular inflammation. Antibody Therapeutics, 8 (4) tbaf025, 350-363. doi: 10.1093/abt/tbaf025
2025
Journal Article
Vascular-protective effects of cerium oxide nanoparticles complexed with iron oxide and methotrexate: reversing atherosclerosis in a murine model
Wu, Yuao, Tran, Huong D. N., Sajin, Dimple, Moonshi, Shehzahdi S., Fithri, Najma Annuria, Kurniawan, Nyoman and Ta, Hang Thu (2025). Vascular-protective effects of cerium oxide nanoparticles complexed with iron oxide and methotrexate: reversing atherosclerosis in a murine model. ACS Nano Medicine, 1 (1) acsnanomed.5c00036, 250-267. doi: 10.1021/acsnanomed.5c00036
2025
Journal Article
Leveraging dielectrophoresis in inertial flow for versatile manipulation of micro and nanoparticles
Cha, Haotian, Ouyang, Lingxi, Chen, Xiangxun, Wu, Yuao, Kang, Xiaoyue, An, Hongjie, Li, Weihua, Nguyen, Nam-Trung and Zhang, Jun (2025). Leveraging dielectrophoresis in inertial flow for versatile manipulation of micro and nanoparticles. Lab on a Chip, 25 (12), 2816-2827. doi: 10.1039/d4lc01037j
2025
Journal Article
VCAM-1 as a common biomarker in inflammatory bowel disease and colorectal cancer: unveiling the dual anti-inflammatory and anti-cancer capacities of anti-VCAM-1 therapies
Pickett, Jessica R., Wu, Yuao and Ta, Hang Thu (2025). VCAM-1 as a common biomarker in inflammatory bowel disease and colorectal cancer: unveiling the dual anti-inflammatory and anti-cancer capacities of anti-VCAM-1 therapies. Cancer and Metastasis Reviews, 44 (2) 40, 2. doi: 10.1007/s10555-025-10258-2
2025
Journal Article
Advancements in using polymeric nanoparticles for blood-brain barrier penetration in neurological disorders
Wu, Yuao, Moonshi, Shehzahdi S. and Ta, Hang Thu (2025). Advancements in using polymeric nanoparticles for blood-brain barrier penetration in neurological disorders. ACS Applied Bio Materials, 8 (6), 4416-4431. doi: 10.1021/acsabm.4c01956
2025
Journal Article
An intimal-lumen model in a microfluidic device: potential platform for atherosclerosis-related studies
Akther, Fahima, Sajin, Dimple, Moonshi, Shehzahdi S., Pickett, Jessica, Wu, Yuao, Zhang, Jun, Nguyen, Nam-Trung and Ta, Hang Thu (2025). An intimal-lumen model in a microfluidic device: potential platform for atherosclerosis-related studies. Lab On a Chip, 25 (3), 354-369. doi: 10.1039/d4lc00868e
2025
Journal Article
Branched silver-iron oxide nanoparticles enabling highly effective targeted and localised drug-free thrombolysis
Vazquez-Prada, Karla X., Moonshi, Shehzahdi S., Wu, Yuao, Peter, Karlheinz, Wang, Xiaowei, Xu, Zhi Ping and Ta, Hang Thu (2025). Branched silver-iron oxide nanoparticles enabling highly effective targeted and localised drug-free thrombolysis. Biomaterials Science, 13 (7), 1683-1696. doi: 10.1039/d4bm01089b
2025
Journal Article
A methotrexate labelled dual metal oxide nanocomposite for long-lasting anti-cancer theranostics
Tang, Joyce L. Y., Moonshi, Shehzahdi S., Wu, Yuao, Cowin, Gary, Vazquez- Prada, Karla X., Tran, Huong D. N., Bulmer, Andrew C. and Ta, Hang Thu (2025). A methotrexate labelled dual metal oxide nanocomposite for long-lasting anti-cancer theranostics. Materials Today Bio, 30 101377, 101377. doi: 10.1016/j.mtbio.2024.101377
2024
Journal Article
Isolation and Characterization of Antibodies Against Vascular Cell Adhesion Molecule-1 Reveals Putative Role for Ig-like Domains 2 and 3 in Cell-to-Cell Interaction
Perera, Binura, Wu, Yuao, Pickett, Jessica R., Panagides, Nadya, Barretto, Francisca M., Fercher, Christian, Sester, David P., Jones, Martina L., Ta, Hang T. and Zacchi, Lucia F. (2024). Isolation and Characterization of Antibodies Against Vascular Cell Adhesion Molecule-1 Reveals Putative Role for Ig-like Domains 2 and 3 in Cell-to-Cell Interaction. International Journal of Molecular Sciences, 25 (24) 13650, 1-21. doi: 10.3390/ijms252413650
2024
Journal Article
Polysuccinimide-based nanoparticle: a nanocarrier with drug release delay and zero burst release properties for effective theranostics of cancer
Moonshi, Shehzahdi S., Vazquez-Prada, Karla X., Adelnia, Hossein, Westra van Holthe, Nicholas J., Wu, Yuao, Tang, Joyce, Bulmer, Andrew C. and Ta, Hang Thu (2024). Polysuccinimide-based nanoparticle: a nanocarrier with drug release delay and zero burst release properties for effective theranostics of cancer. Applied Materials Today, 37 102150, 1-19. doi: 10.1016/j.apmt.2024.102150
2024
Journal Article
Modeling foam cell formation in a hydrogel-based 3D-intimal model: a study of the role of multi-diseases during early atherosclerosis
Akther, Fahima, Sajin, Dimple, Moonshi, Shehzahdi S., Wu, Yuao, Vazquez-Prada, Karla X. and Ta, Hang Thu (2024). Modeling foam cell formation in a hydrogel-based 3D-intimal model: a study of the role of multi-diseases during early atherosclerosis. Advanced Biology, 8 (4) e2300463, 1-14. doi: 10.1002/adbi.202300463
2023
Journal Article
A bioactive disintegrable polymer nanoparticle for synergistic vascular anticalcification
Adelnia, Hossein, Moonshi, Shehzahdi Shebbrin, Wu, Yuao, Bulmer, Andrew C., Mckinnon, Ryan, Fastier-Wooller, Jarred William, Blakey, Idriss and Ta, Hang Thu (2023). A bioactive disintegrable polymer nanoparticle for synergistic vascular anticalcification. ACS Nano, 17 (19), 18775-18791. doi: 10.1021/acsnano.3c03041
2023
Journal Article
Spiky silver–iron oxide nanohybrid for effective dual-imaging and synergistic thermo-chemotherapy
Moonshi, Shehzahdi S., Vazquez-Prada, Karla X., Tang, Joyce, Westra van Holthe, Nicholas J., Cowin, Gary, Wu, Yuao, Tran, Huong D. N., Mckinnon, Ryan, Bulmer, Andrew C. and Ta, Hang Thu (2023). Spiky silver–iron oxide nanohybrid for effective dual-imaging and synergistic thermo-chemotherapy. ACS Applied Materials and Interfaces, 15 (36), 42153-42169. doi: 10.1021/acsami.3c04696
2023
Journal Article
Targeting endothelial VCAM-1 in atherosclerosis: drug discovery and development of VCAM-1-directed novel therapeutics
Pickett, Jess R., Wu, Yuao, Zacchi, Lucia F. and Ta, Hang T. (2023). Targeting endothelial VCAM-1 in atherosclerosis: drug discovery and development of VCAM-1-directed novel therapeutics. Cardiovascular Research, 119 (13), 2278-2293. doi: 10.1093/cvr/cvad130
2023
Journal Article
Frontispiece - A Spiky Silver‐Iron Oxide Nanoparticle for Highly Efficient Targeted Photothermal Therapy and Multimodal Imaging of Thrombosis (Small 11/2023)
Vazquez‐Prada, Karla X., Moonshi, Shehzahdi S., Wu, Yuao, Akther, Fahima, Tse, Brian W.C., Sokolowski, Kamil A., Peter, Karlheinz, Wang, Xiaowei, Xu, Zhi Ping (Gordon) and Ta, Hang Thu (2023). Frontispiece - A Spiky Silver‐Iron Oxide Nanoparticle for Highly Efficient Targeted Photothermal Therapy and Multimodal Imaging of Thrombosis (Small 11/2023). Small, 19 (11) 2370070. doi: 10.1002/smll.202370070
2023
Journal Article
A spiky silver‐iron oxide nanoparticle for highly efficient targeted photothermal therapy and multimodal imaging of thrombosis
Vazquez‐Prada, Karla X., Moonshi, Shehzahdi S., Wu, Yuao, Akther, Fahima, Tse, Brian W.C., Sokolowski, Kamil A., Peter, Karlheinz, Wang, Xiaowei, Xu, Gordon and Ta, Hang Thu (2023). A spiky silver‐iron oxide nanoparticle for highly efficient targeted photothermal therapy and multimodal imaging of thrombosis. Small, 19 (11) 2205744, 1-15. doi: 10.1002/smll.202205744
2023
Journal Article
Polymeric nanomaterial strategies to encapsulate and deliver biological drugs: points to consider between methods
Chen, Xiangxun, Wu, Yuao, Dau, Van Thanh, Nguyen, Nam-Trung and Ta, Hang Thu (2023). Polymeric nanomaterial strategies to encapsulate and deliver biological drugs: points to consider between methods. Biomaterials Science, 11 (6), 1923-1947. doi: 10.1039/d2bm01594c
2022
Journal Article
Placenta‐derived mesenchymal stem cells for treatment of diseases: a clinically relevant source
Moonshi, Shehzahdi S., Adelnia, Hossein, Wu, Yuao and Ta, Hang T. (2022). Placenta‐derived mesenchymal stem cells for treatment of diseases: a clinically relevant source. Advanced Therapeutics, 5 (10) 2200054, 1-14. doi: 10.1002/adtp.202200054
Supervision
Availability
- Dr Yuao Wu is:
- Available for supervision
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Media
Enquiries
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