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Mr Carl Soltau
Mr

Carl Soltau

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Overview

Background

Mr Carl Soltau is a medicinal chemist focused on developing novel therapeutic strategies and understanding the mechanisms required to address major challenges in preserving human health. He obtained his PhD in 2026 from the Queensland University of Technology, where his research has centred on the design and synthesis of nitroxide-based hybrid molecules with mutiple modes of action, including anti-inflammatory, and anticancer activity. In his current current role, he focus on the synthesis of fluorescent antibiotic derivatives as to better understand drug–target interactions, localisation, and mechanisms of resistance in bacterial systems.

Overall, his research is driven by a broader goal of uncovering how molecular design can be leveraged to better understand and overcome complex disease processes.

Availability

Mr Carl Soltau is:
Available for supervision

Qualifications

  • Bachelor of Physics and Chemistry, Queensland University of Technology
  • Masters (Research) of Organic Chemistry, Queensland University of Technology

Works

Search Professor Carl Soltau’s works on UQ eSpace

8 works between 2022 and 2026

1 - 8 of 8 works

2026

Journal Article

Steroidal-nitroxide hybrid sustains oxidative stress and enhances cisplatin efficacy in vitro across multiple cancer cell lines

Soltau, Carl P., Tay, Ban Qi, Richard, Derek J., Bottle, Steven E. and Adams, Mark N. (2026). Steroidal-nitroxide hybrid sustains oxidative stress and enhances cisplatin efficacy in vitro across multiple cancer cell lines. Biomedicine & Pharmacotherapy, 198 119348, 119348. doi: 10.1016/j.biopha.2026.119348

Steroidal-nitroxide hybrid sustains oxidative stress and enhances cisplatin efficacy in vitro across multiple cancer cell lines

2026

Journal Article

Structure-activity relationship of steroidal-nitroxide hybrids: dual-modulators of glucocorticoid receptor signalling and cellular redox state

Soltau, Carl P., Tay, Ban Qi, Martyn, Alexander P., Richard, Derek J., Adams, Mark N. and Bottle, Steven E. (2026). Structure-activity relationship of steroidal-nitroxide hybrids: dual-modulators of glucocorticoid receptor signalling and cellular redox state. European Journal of Medicinal Chemistry, 307 118655, 1-16. doi: 10.1016/j.ejmech.2026.118655

Structure-activity relationship of steroidal-nitroxide hybrids: dual-modulators of glucocorticoid receptor signalling and cellular redox state

2026

Journal Article

Redox-active nitroxides enhance cisplatin efficacy against cervical cancer

Soltau, Carl P., Sinha, Debottam, Patil, Lakshita P., Moseley, Philip M., Rayner, Cassie L., Barnett, Nigel L., Richard, Derek J., Bottle, Steven E., Frazer, Ian H. and Martyn, Alexander P. (2026). Redox-active nitroxides enhance cisplatin efficacy against cervical cancer. Redox Biology, 89 103989, 1-13. doi: 10.1016/j.redox.2025.103989

Redox-active nitroxides enhance cisplatin efficacy against cervical cancer

2025

Journal Article

Novel reactions of a profluorescent nitroxide probe with ozone showcase a cascade of solvent-dependent redox reactions

Brown, Zachary E., Soltau, Carl P., Marshall, David L., Bottle, Steven E. and Miljevic, Branka (2025). Novel reactions of a profluorescent nitroxide probe with ozone showcase a cascade of solvent-dependent redox reactions. RSC Advances, 15 (32), 26395-26402. doi: 10.1039/d5ra03412d

Novel reactions of a profluorescent nitroxide probe with ozone showcase a cascade of solvent-dependent redox reactions

2025

Conference Publication

Steroid-nitroxide hybrid compound protects the retina in a model of CNV

Toto, Rimaz, Soltau, Carl P., Rayner, Cassie L., Bottle, Steven E. and Barnett, Nigel L. (2025). Steroid-nitroxide hybrid compound protects the retina in a model of CNV. XVIII International Symposium on Retinal Degeneration, Torremolinos, Spain, 23-27 October 2023. Cham, Switzerland: Springer Cham. doi: 10.1007/978-3-031-76550-6_81

Steroid-nitroxide hybrid compound protects the retina in a model of CNV

2024

Journal Article

Synthesis of anti-oxidant steroids by hybridisation with nitroxides

Soltau, Carl P., Weir, Naomi E., Martyn, Alexander P. and Bottle, Steven E. (2024). Synthesis of anti-oxidant steroids by hybridisation with nitroxides. Synthesis, 56 (21), 3289-3296. doi: 10.1055/a-2232-8240

Synthesis of anti-oxidant steroids by hybridisation with nitroxides

2023

Journal Article

An exploration of small molecules that bind human single-stranded DNA binding protein 1

Schuurs, Zachariah P., Martyn, Alexander P., Soltau, Carl P., Beard, Sam, Shah, Esha T., Adams, Mark N., Croft, Laura V., O'Byrne, Kenneth J., Richard, Derek J. and Gandhi, Neha S. (2023). An exploration of small molecules that bind human single-stranded DNA binding protein 1. Biology, 12 (11) 1405, 1-23. doi: 10.3390/biology12111405

An exploration of small molecules that bind human single-stranded DNA binding protein 1

2022

Journal Article

Reactions of sulfoxides with reactive oxygen species to reveal the radical chemistry of pollution-derived particulate matter

Soltau, Carl P., Brown, Zac E., Brock, Aidan J., Martyn, Alexander P., Blinco, James P., Miljevic, Branka, McMurtrie, John C. and Bottle, Steven E. (2022). Reactions of sulfoxides with reactive oxygen species to reveal the radical chemistry of pollution-derived particulate matter. Chemical Communications, 58 (74), 10416-10419. doi: 10.1039/d2cc04024g

Reactions of sulfoxides with reactive oxygen species to reveal the radical chemistry of pollution-derived particulate matter

Supervision

Availability

Mr Carl Soltau is:
Available for supervision

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Media

Enquiries

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communications@uq.edu.au