Overview
Background
Mr Carl Soltau is a medicinal chemist focused on developing novel therapeutic strategies and understanding the mechanisms required to address major challenges in preserving human health. He obtained his PhD in 2026 from the Queensland University of Technology, where his research has centred on the design and synthesis of nitroxide-based hybrid molecules with mutiple modes of action, including anti-inflammatory, and anticancer activity. In his current current role, he focus on the synthesis of fluorescent antibiotic derivatives as to better understand drug–target interactions, localisation, and mechanisms of resistance in bacterial systems.
Overall, his research is driven by a broader goal of uncovering how molecular design can be leveraged to better understand and overcome complex disease processes.
Availability
- Mr Carl Soltau is:
- Available for supervision
Qualifications
- Bachelor of Physics and Chemistry, Queensland University of Technology
- Masters (Research) of Organic Chemistry, Queensland University of Technology
Works
Search Professor Carl Soltau’s works on UQ eSpace
2026
Journal Article
Steroidal-nitroxide hybrid sustains oxidative stress and enhances cisplatin efficacy in vitro across multiple cancer cell lines
Soltau, Carl P., Tay, Ban Qi, Richard, Derek J., Bottle, Steven E. and Adams, Mark N. (2026). Steroidal-nitroxide hybrid sustains oxidative stress and enhances cisplatin efficacy in vitro across multiple cancer cell lines. Biomedicine & Pharmacotherapy, 198 119348, 119348. doi: 10.1016/j.biopha.2026.119348
2026
Journal Article
Structure-activity relationship of steroidal-nitroxide hybrids: dual-modulators of glucocorticoid receptor signalling and cellular redox state
Soltau, Carl P., Tay, Ban Qi, Martyn, Alexander P., Richard, Derek J., Adams, Mark N. and Bottle, Steven E. (2026). Structure-activity relationship of steroidal-nitroxide hybrids: dual-modulators of glucocorticoid receptor signalling and cellular redox state. European Journal of Medicinal Chemistry, 307 118655, 1-16. doi: 10.1016/j.ejmech.2026.118655
2026
Journal Article
Redox-active nitroxides enhance cisplatin efficacy against cervical cancer
Soltau, Carl P., Sinha, Debottam, Patil, Lakshita P., Moseley, Philip M., Rayner, Cassie L., Barnett, Nigel L., Richard, Derek J., Bottle, Steven E., Frazer, Ian H. and Martyn, Alexander P. (2026). Redox-active nitroxides enhance cisplatin efficacy against cervical cancer. Redox Biology, 89 103989, 1-13. doi: 10.1016/j.redox.2025.103989
2025
Journal Article
Novel reactions of a profluorescent nitroxide probe with ozone showcase a cascade of solvent-dependent redox reactions
Brown, Zachary E., Soltau, Carl P., Marshall, David L., Bottle, Steven E. and Miljevic, Branka (2025). Novel reactions of a profluorescent nitroxide probe with ozone showcase a cascade of solvent-dependent redox reactions. RSC Advances, 15 (32), 26395-26402. doi: 10.1039/d5ra03412d
2025
Conference Publication
Steroid-nitroxide hybrid compound protects the retina in a model of CNV
Toto, Rimaz, Soltau, Carl P., Rayner, Cassie L., Bottle, Steven E. and Barnett, Nigel L. (2025). Steroid-nitroxide hybrid compound protects the retina in a model of CNV. XVIII International Symposium on Retinal Degeneration, Torremolinos, Spain, 23-27 October 2023. Cham, Switzerland: Springer Cham. doi: 10.1007/978-3-031-76550-6_81
2024
Journal Article
Synthesis of anti-oxidant steroids by hybridisation with nitroxides
Soltau, Carl P., Weir, Naomi E., Martyn, Alexander P. and Bottle, Steven E. (2024). Synthesis of anti-oxidant steroids by hybridisation with nitroxides. Synthesis, 56 (21), 3289-3296. doi: 10.1055/a-2232-8240
2023
Journal Article
An exploration of small molecules that bind human single-stranded DNA binding protein 1
Schuurs, Zachariah P., Martyn, Alexander P., Soltau, Carl P., Beard, Sam, Shah, Esha T., Adams, Mark N., Croft, Laura V., O'Byrne, Kenneth J., Richard, Derek J. and Gandhi, Neha S. (2023). An exploration of small molecules that bind human single-stranded DNA binding protein 1. Biology, 12 (11) 1405, 1-23. doi: 10.3390/biology12111405
2022
Journal Article
Reactions of sulfoxides with reactive oxygen species to reveal the radical chemistry of pollution-derived particulate matter
Soltau, Carl P., Brown, Zac E., Brock, Aidan J., Martyn, Alexander P., Blinco, James P., Miljevic, Branka, McMurtrie, John C. and Bottle, Steven E. (2022). Reactions of sulfoxides with reactive oxygen species to reveal the radical chemistry of pollution-derived particulate matter. Chemical Communications, 58 (74), 10416-10419. doi: 10.1039/d2cc04024g
Supervision
Availability
- Mr Carl Soltau is:
- Available for supervision
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Media
Enquiries
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