
Overview
Background
Hemamali Samaratunga MBBS (Hons) LRCP (London) MRCS (UK) FRCPA, FRCPath
- Specialist Anatomical Pathologist, Managing Director, Aquesta Specialised Uropathology
- Full Professor, University of Queensland Faculty of Medicine
- Visiting Medical Officer, Greenslopes Private Hospital
Hemamali graduated with honours from the University of Sri Lanka, Colombo Medical School and completed Pathology specialty training in Queensland. She held a number of consultant posts in both hospital and private practice. In 2008 she established Aquesta Uropathology which now provides diagnostic uropathology services to the majority of urologists in Queensland and Northern New South Wales. In addition to this she maintains a large second opinion consultation practice with requests obtained from throughout Australia and from overseas.
She is active in Genitourinary Pathology research with collaborators in Australia, USA, Canada, Karolinska Institute in Sweden and the Wellington School of Medicine in New Zealand. She held the position of Secretary of the International Society of Urological Pathology from 2015 to 2019.
She was a contributor to the 2004, 2015 and 2022 World Health Organization (WHO) books on Classification of Tumours: Pathology and Genetics of Tumours of the Urinary and Male Reproductive System. She participated in the 2015 revision of the WHO Tumour Classification in Zurich, Switzerland (4th edition) as member, Prostate Tumour Panel. She was a representative of the Expert Groups formulating structured reporting protocols for the Royal College Pathologists of Australasia on kidney, testis and prostate cancer and is currently chairperson of the structured reporting protocols for Genitourinary cancer. She is also currently the Convener for the RCPA Uropathology Quality Assurance Program.
Qualifications
MBBS (HONS) LRCP (London) MRCS (UK) FRCPA FRCPath
Current UQ Appointments
Academic Title-Professor
Non-UQ Appointments
2008 - current: Specialist Anatomical Pathologist & Managing Director, Aquesta Specialized Uropathology
2015 - Current: Visiting Medical Officer, Greenslopes Private Hospital
2003 - 2021: Visiting Medical Officer, Princess Alexandra Hospital
June 2001 - Oct 2008: Specialist Anatomical Pathologist, Sullivan Nicolaides Pathology, Brisbane
1993 - 1997: Specialist Anatomical Pathologist, Royal Brisbane Hospital
1998 - 2001: Senior Anatomical Pathologist, North Brisbane Hospitals Board
Research Interests
- Granular tumour necrosis
- Diagnosis of limited adenocarcinoma on prostate needle biopsy
- Ductal adenocarcinoma of prostate
- Mucinous adenocarcinoma of prostate
- Radical prostatectomy handling and reporting
- Micropapillary urothelial cancer
- Mimics of bladder cancer
Awards and other Esteem Indicators
2017 Admitted to Fellowship of the Royal College of Pathologists, London (FRC Path) for sustained excellence in published works
2022 Awarded the Grawitz Medal of the International Society of Urological Pathology for distinguished service to the discipline of Urological Pathology
2023 Author of the publication Percentage grade 4 tumour predicts outcome for prostate adenocarcinoma in needle biopsies from patients with advanced disease: Ten year data from the TROG 03.04 RADAR Trial. Pathology 54: 49- 54, awarded the prize of
Article of the Year by the Royal College of Pathologists of Australasia.
2024 Distinguished Fellowship Award of the Royal College Pathologists of Australasia
For distinguished service to the discipline of Urological Pathology
Keywords
Pathology, Genitourinary cancer, Prostate, Kidney, Urinary tract, Testis, Penis
Availability
- Professor Hemamali Samaratunga is:
- Available for supervision
Fields of research
Research impacts
She has over 320 scientific publications and has a Google Scholar H-index of 56 with 18150 citations. To date she has authored or co-authored 28 books, 21 book chapters and 274 peer-reviewed publications. Apart from her primary research activities Professor Samaratunga actively collaborates with other research groups and is a regular contributor - often as primary or senior author to international research consortia. One notable contribution has been her involvement in the development of artificial intelligence programs for the reporting of prostate cancer. In collaborative studies involving colleagues from the Netherlands, Sweden, Australia, New Zealand and the United States she was chosen to be one of three expert pathologists to review all cases, thus setting the gold standard for the diagnosis and grading of prostate cancer. These studies have been published in highly prestigious journals as noted in her CV. Importantly in comparative studies, the AI program informed by the findings of group of three pathologists that included Professor Samaratunga, outperformed all other AI programs.
Works
Search Professor Hemamali Samaratunga’s works on UQ eSpace
2016
Journal Article
International Society of Urological Pathology (ISUP) grading of prostate cancer
Egevad, Lars, Delahunt, Brett, Evans, Andrew J., Grignon, David J., Kench, James G., Kristiansen, Glen, Leite, Katia R., Samaratunga, Hemamali and Srigley, John R. (2016). International Society of Urological Pathology (ISUP) grading of prostate cancer. American Journal of Surgical Pathology, 40 (6), 858-861. doi: 10.1097/PAS.0000000000000642
2016
Journal Article
Decreased apoptosis repressor with caspase recruitment domain confers resistance to sunitinib in renal cell carcinoma through alternate angiogenesis pathways
Gobe, Glenda C., Ng, Keng Lim, Small, David M., Vesey, David A., Johnson, David W., Samaratunga, Hemamali, Oliver, Kimberley, Wood, Simon, Barclay, Johanna L., Rajandram, Retnagowri, Li, Li and Morais, Christudas (2016). Decreased apoptosis repressor with caspase recruitment domain confers resistance to sunitinib in renal cell carcinoma through alternate angiogenesis pathways. Biochemical and Biophysical Research Communications, 473 (1), 47-53. doi: 10.1016/j.bbrc.2016.03.048
2016
Journal Article
Immunohistochemistry of ductal adenocarcinoma of the prostate and adenocarcinomas of non-prostatic origin: A comparative study
Seipel, Amanda H., Samaratunga, Hemamali, Delahunt, Brett, Wiklund, Peter, Clements, Mark and Egevad, Lars (2016). Immunohistochemistry of ductal adenocarcinoma of the prostate and adenocarcinomas of non-prostatic origin: A comparative study. APMIS, 124 (4), 263-270. doi: 10.1111/apm.12504
2016
Journal Article
Prostate cancer grading: Recent developments and future directions
Delahunt, Brett, Egevad, Lars, Grignon, David J., Srigley, John R. and Samaratunga, Hema (2016). Prostate cancer grading: Recent developments and future directions. BJU International, 117 (S4), 7-8. doi: 10.1111/bju.13467
2016
Journal Article
Gleason and Fuhrman no longer make the grade
Delahunt, Brett, Egevad, Lars, Samaratunga, Hemamali, Martignoni, Guido, Nacey, John N. and Srigley, John R. (2016). Gleason and Fuhrman no longer make the grade. Histopathology, 68 (4), 475-481. doi: 10.1111/his.12803
2016
Journal Article
Histologic prognostic markers for renal cell neoplasia
Delahunt, Brett, Samaratunga, Hemamali and Kenwright, Diane N. (2016). Histologic prognostic markers for renal cell neoplasia. Diagnostic Histopathology, 22 (2), 65-72. doi: 10.1016/j.mpdhp.2016.01.002
2016
Conference Publication
Immunohistochemical expression of kidney injury molecule-1 Aids in the differentiation of chromophobe renal cell carcinoma and renal oncocytoma in an Australian cohort
Ng, Keng, Wood, Simon, Gobe, Glenda, Samaratunga, Hemamali, Morais, Christudas, Small, David, Oh, Seung, Del Vecchio, Sharon and Ellis, Robert (2016). Immunohistochemical expression of kidney injury molecule-1 Aids in the differentiation of chromophobe renal cell carcinoma and renal oncocytoma in an Australian cohort. 14th Urological Association of Asia Congress, Singapore, 20-24 July 2016. Richmond, VIC, Australia: Wiley-Blackwell.
2016
Conference Publication
Histopathological diagnosis of chromophobe renal cell carcinoma and renal oncocytoma: immunohistochemistry and multispectral imaging of cytokeratin 7, leptin and caveolin-1
Ng, N., Morais, C., Samaratunga, H., Gobe, G. and Wood, S. (2016). Histopathological diagnosis of chromophobe renal cell carcinoma and renal oncocytoma: immunohistochemistry and multispectral imaging of cytokeratin 7, leptin and caveolin-1. 69th Annual Scientific Meeting of the Urological Society of Australia and New Zealand, Gold Coast, QLD, Australia, 16-19 April 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/bju.13452
2016
Conference Publication
Prostatic fluid mRNA and microRNA biomarkers: an emerging paradigm for noninvasive diagnosis of prostate cancer
Roberts, Matthew J., Richards, R., Chow, C. W. K., Schirra, H., Buck, M., Selth, L. A., Doi, S. A., Samaratunga, H., Perry-Keene, J., Payton, D., Yaxley, J., Lavin, M. F. and Gardiner, R. A. (2016). Prostatic fluid mRNA and microRNA biomarkers: an emerging paradigm for noninvasive diagnosis of prostate cancer. ANZUP Annual Scientific Meeting, GU Cancer: Expanding our Horizons, Brisbane, QLD Australia, 10-12 July 2016. Chichester, West Sussex United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/ajco.12558
2016
Journal Article
Accuracy of prostate biopsies for predicting Gleason score in radical prostatectomy specimens: nationwide trends 2000-2012
Danneman, Daniela, Drevin, Linda, Delahunt, Brett, Samaratunga, Hemamali, Robinson, David, Bratt, Ola, Loeb, Stacy, Stattin, Par and Egevad, Lars (2016). Accuracy of prostate biopsies for predicting Gleason score in radical prostatectomy specimens: nationwide trends 2000-2012. BJU International, 119 (1), 50-56. doi: 10.1111/bju.13458
2016
Conference Publication
A new prostate-based biofluid for the detection of prostate cancer and diagnostic performance comparison using mRNA biomarkers
Roberts, M., Chow, C., Schirra, H., Richards, R., Buck, M., Doi, S., Samaratunga, H., Yaxley, J., Lavin, M. and Gardiner, R. (2016). A new prostate-based biofluid for the detection of prostate cancer and diagnostic performance comparison using mRNA biomarkers. 69th Annual Scientific Meeting of the Urological-Society-of-Australia-and-New Zealand, Gold Coast, Australia, 16-19 April 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. doi: 10.1111/bju.13452
2016
Journal Article
The 2014 international society of urological pathology (ISUP) consensus conference on gleason grading of prostatic carcinoma definition of grading patterns and proposal for a new grading system
Epstein, Jonathan I., Egevad, Lars, Amin, Mahul B., Delahunt, Brett, Srigley, John R., Humphrey, Peter A., Al-Hussain, Turki, Algaba, Ferran, Aron, Manju, Berman, David, Berney, Daniel, Brimo, Fadi, Cao, Dengfeng, Cheville, John, Clouston, David, Colecchia, Maurizio, Comperat, Eva, Da Cunha, Isabela Werneck, De Marzo, Angelo, Ertoy, Dilek, Fine, Samson, Foster, Christopher, Grignon, David, Gupta, Nilesh, Gupta, Ruta, Kench, James, Kristiansen, Glen, Kunju, Lakshmi, Leite, Katia Ramos Moreira ... The Grading Committee (2016). The 2014 international society of urological pathology (ISUP) consensus conference on gleason grading of prostatic carcinoma definition of grading patterns and proposal for a new grading system. American Journal of Surgical Pathology, 40 (2), 244-252. doi: 10.1097/PAS.0000000000000530
2016
Conference Publication
Expression of S100 calcium binding protein A1 (S100A1) aids in the differentiation of renal cell carcinoma versus normal kidney tissue
Del Vecchio, S., Ng, K., Ellis, R., Samaratunga, H., Gobe, G. and Wood, S. (2016). Expression of S100 calcium binding protein A1 (S100A1) aids in the differentiation of renal cell carcinoma versus normal kidney tissue. The 15th Asian Pacific Congress of Nephrology (APCN) and 52nd ANZSN ASM, Perth, WA, Australia, 17–21 September 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12888
2016
Conference Publication
A Randomized Controlled Trial of Robotic Versus Open Radical Prostatectomy: Early Outcomes
Gardiner, Robert ('Frank'), Yaxley, John W., Coughlin, Geoffrey D., Chambers, Suzanne K., Occhipinti, Stefano, Samaratunga, Hema, Zaidlewicz, Leah, Dunglison, Nigel, Carter, Rob, Williams, Scott, Payton, Diane J., Perry-Keene, Joanna and Lavin, Martin F. (2016). A Randomized Controlled Trial of Robotic Versus Open Radical Prostatectomy: Early Outcomes. ANZUP Annual Scientific Meeting, GU Cancer: Expanding our Horizons, Brisbane, Australia, 10-12 July 2016. West Sussex, United Kingdom: Wiley. doi: 10.1111/ajco.12557
2016
Journal Article
Multifocal primary neoplasms in kidney allografts: evaluation of two cases
Ellis, Robert J., Ng, Keng Lim, Samaratunga, Hemamali, Del Vecchio, Sharon J., Wood, Simon T. and Gobe, Glenda C. (2016). Multifocal primary neoplasms in kidney allografts: evaluation of two cases. Journal of Kidney Cancer and VHL, 3 (2), 14-22. doi: 10.15586/jkcvhl.2016.53
2015
Journal Article
Cancer stem cell markers in prostate cancer: An immunohistochemical study of ALDH1, SOX2 and EZH2
Matsika, Admire, Srinivasan, Bhuvana, Day, Christopher, Mader, Sabina Ann, Kiernan, Deirdre Margaret, Broomfield, Amy, Fu, Jinlin, Hooper, John D., Kench, James G. and Samaratunga, Hemamali (2015). Cancer stem cell markers in prostate cancer: An immunohistochemical study of ALDH1, SOX2 and EZH2. Pathology, 47 (7), 622-628. doi: 10.1097/PAT.0000000000000325
2015
Journal Article
Magnitude of PD-1, PD-L1 and T lymphocyte expression on tissue from castration-resistant prostate adenocarcinoma: an exploratory analysis
Massari, Francesco, Ciccarese, Chiara, Calio, Anna, Munari, Enrico, Cima, Luca, Porcaro, Antonio Benito, Novella, Giovanni, Artibani, Walter, Sava, Teodoro, Eccher, Albino, Ghimenton, Claudio, Bertoldo, Francesco, Scarpa, Aldo, Sperandio, Nicola, Porta, Camillo, Bronte, Vincenzo, Chilosi, Marco, Bogina, Giuseppe, Zamboni, Giuseppe, Tortora, Giampaolo, Samaratunga, Hemamali, Martignoni, Guido and Brunelli, Matteo (2015). Magnitude of PD-1, PD-L1 and T lymphocyte expression on tissue from castration-resistant prostate adenocarcinoma: an exploratory analysis. Targeted Oncology, 11 (3), 1-7. doi: 10.1007/s11523-015-0396-3
2015
Journal Article
Is transperineal prostate biopsy more accurate than transrectal biopsy in determining final Gleason score and clinical risk category? A comparative analysis
Scott, Susan, Samaratunga, Hemamali, Chabert, Charles, Breckenridge, Michelle and Gianduzzo, Troy (2015). Is transperineal prostate biopsy more accurate than transrectal biopsy in determining final Gleason score and clinical risk category? A comparative analysis. BJU International, 116 (S3), 26-30. doi: 10.1111/bju.13165
2015
Journal Article
The prognostic significance of the 2014 International Society of Urological Pathology (ISUP) grading system for prostate cancer
Samaratunga, Hemamali, Delahunt, Brett, Gianduzzo, Troy, Coughlin, Geoff, Duffy, David, LeFevre, Ian, Johannsen, Shulammite, Egevad, Lars and Yaxley, John (2015). The prognostic significance of the 2014 International Society of Urological Pathology (ISUP) grading system for prostate cancer. Pathology, 47 (6), 515-519. doi: 10.1097/PAT.0000000000000315
2015
Journal Article
Diagnostic performance of expression of PCA3, Hepsin and miR biomarkers inejaculate in combination with serum PSA for the detection of prostate cancer
Roberts, Matthew J., Chow, Clement W., Schirra, Horst J., Richards, Renee, Buck, Marion, Selth, Luke A., Doi, Suhail A. R., Samaratunga, Hema, Perry-Keene, Joanna, Payton, Diane, Yaxley, John, Lavin, Martin F. and Gardiner, Robert A. (2015). Diagnostic performance of expression of PCA3, Hepsin and miR biomarkers inejaculate in combination with serum PSA for the detection of prostate cancer. Prostate, 75 (5), 539-549. doi: 10.1002/pros.22942
Supervision
Availability
- Professor Hemamali Samaratunga is:
- Available for supervision
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Supervision history
Completed supervision
-
2020
Doctor Philosophy
Exploring Resistance of Renal Cell Carcinoma to Sunitinib Therapy
Associate Advisor
Other advisors: Associate Professor David Vesey
-
2019
Doctor Philosophy
Cellular and molecular mechanisms of pancreatitis in atrophy and regeneration
Associate Advisor
Media
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