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Professor Hemamali Samaratunga
Professor

Hemamali Samaratunga

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Overview

Background

Hemamali Samaratunga MBBS (Hons) LRCP (London) MRCS (UK) FRCPA, FRCPath

  • Specialist Anatomical Pathologist, Managing Director, Aquesta Specialised Uropathology
  • Full Professor, University of Queensland Faculty of Medicine
  • Visiting Medical Officer, Greenslopes Private Hospital

Hemamali graduated with honours from the University of Sri Lanka, Colombo Medical School and completed Pathology specialty training in Queensland. She held a number of consultant posts in both hospital and private practice. In 2008 she established Aquesta Uropathology which now provides diagnostic uropathology services to the majority of urologists in Queensland and Northern New South Wales. In addition to this she maintains a large second opinion consultation practice with requests obtained from throughout Australia and from overseas.

She is active in Genitourinary Pathology research with collaborators in Australia, USA, Canada, Karolinska Institute in Sweden and the Wellington School of Medicine in New Zealand. She held the position of Secretary of the International Society of Urological Pathology from 2015 to 2019.

She was a contributor to the 2004, 2015 and 2022 World Health Organization (WHO) books on Classification of Tumours: Pathology and Genetics of Tumours of the Urinary and Male Reproductive System. She participated in the 2015 revision of the WHO Tumour Classification in Zurich, Switzerland (4th edition) as member, Prostate Tumour Panel. She was a representative of the Expert Groups formulating structured reporting protocols for the Royal College Pathologists of Australasia on kidney, testis and prostate cancer and is currently chairperson of the structured reporting protocols for Genitourinary cancer. She is also currently the Convener for the RCPA Uropathology Quality Assurance Program.

Qualifications

MBBS (HONS) LRCP (London) MRCS (UK) FRCPA FRCPath

Current UQ Appointments

Academic Title-Professor

Non-UQ Appointments

2008 - current: Specialist Anatomical Pathologist & Managing Director, Aquesta Specialized Uropathology

2015 - Current: Visiting Medical Officer, Greenslopes Private Hospital

2003 - 2021: Visiting Medical Officer, Princess Alexandra Hospital

June 2001 - Oct 2008: Specialist Anatomical Pathologist, Sullivan Nicolaides Pathology, Brisbane

1993 - 1997: Specialist Anatomical Pathologist, Royal Brisbane Hospital

1998 - 2001: Senior Anatomical Pathologist, North Brisbane Hospitals Board

Research Interests

  • Granular tumour necrosis
  • Diagnosis of limited adenocarcinoma on prostate needle biopsy
  • Ductal adenocarcinoma of prostate
  • Mucinous adenocarcinoma of prostate
  • Radical prostatectomy handling and reporting
  • Micropapillary urothelial cancer
  • Mimics of bladder cancer

Awards and other Esteem Indicators

2017 Admitted to Fellowship of the Royal College of Pathologists, London (FRC Path) for sustained excellence in published works

2022 Awarded the Grawitz Medal of the International Society of Urological Pathology for distinguished service to the discipline of Urological Pathology

2023 Author of the publication Percentage grade 4 tumour predicts outcome for prostate adenocarcinoma in needle biopsies from patients with advanced disease: Ten year data from the TROG 03.04 RADAR Trial. Pathology 54: 49- 54, awarded the prize of

Article of the Year by the Royal College of Pathologists of Australasia.

2024 Distinguished Fellowship Award of the Royal College Pathologists of Australasia

For distinguished service to the discipline of Urological Pathology

Keywords

Pathology, Genitourinary cancer, Prostate, Kidney, Urinary tract, Testis, Penis

Availability

Professor Hemamali Samaratunga is:
Available for supervision

Research impacts

She has over 320 scientific publications and has a Google Scholar H-index of 56 with 18150 citations. To date she has authored or co-authored 28 books, 21 book chapters and 274 peer-reviewed publications. Apart from her primary research activities Professor Samaratunga actively collaborates with other research groups and is a regular contributor - often as primary or senior author to international research consortia. One notable contribution has been her involvement in the development of artificial intelligence programs for the reporting of prostate cancer. In collaborative studies involving colleagues from the Netherlands, Sweden, Australia, New Zealand and the United States she was chosen to be one of three expert pathologists to review all cases, thus setting the gold standard for the diagnosis and grading of prostate cancer. These studies have been published in highly prestigious journals as noted in her CV. Importantly in comparative studies, the AI program informed by the findings of group of three pathologists that included Professor Samaratunga, outperformed all other AI programs.

Works

Search Professor Hemamali Samaratunga’s works on UQ eSpace

294 works between 1988 and 2024

141 - 160 of 294 works

2016

Journal Article

International Society of Urological Pathology (ISUP) grading of prostate cancer

Egevad, Lars, Delahunt, Brett, Evans, Andrew J., Grignon, David J., Kench, James G., Kristiansen, Glen, Leite, Katia R., Samaratunga, Hemamali and Srigley, John R. (2016). International Society of Urological Pathology (ISUP) grading of prostate cancer. American Journal of Surgical Pathology, 40 (6), 858-861. doi: 10.1097/PAS.0000000000000642

International Society of Urological Pathology (ISUP) grading of prostate cancer

2016

Journal Article

Decreased apoptosis repressor with caspase recruitment domain confers resistance to sunitinib in renal cell carcinoma through alternate angiogenesis pathways

Gobe, Glenda C., Ng, Keng Lim, Small, David M., Vesey, David A., Johnson, David W., Samaratunga, Hemamali, Oliver, Kimberley, Wood, Simon, Barclay, Johanna L., Rajandram, Retnagowri, Li, Li and Morais, Christudas (2016). Decreased apoptosis repressor with caspase recruitment domain confers resistance to sunitinib in renal cell carcinoma through alternate angiogenesis pathways. Biochemical and Biophysical Research Communications, 473 (1), 47-53. doi: 10.1016/j.bbrc.2016.03.048

Decreased apoptosis repressor with caspase recruitment domain confers resistance to sunitinib in renal cell carcinoma through alternate angiogenesis pathways

2016

Journal Article

Immunohistochemistry of ductal adenocarcinoma of the prostate and adenocarcinomas of non-prostatic origin: A comparative study

Seipel, Amanda H., Samaratunga, Hemamali, Delahunt, Brett, Wiklund, Peter, Clements, Mark and Egevad, Lars (2016). Immunohistochemistry of ductal adenocarcinoma of the prostate and adenocarcinomas of non-prostatic origin: A comparative study. APMIS, 124 (4), 263-270. doi: 10.1111/apm.12504

Immunohistochemistry of ductal adenocarcinoma of the prostate and adenocarcinomas of non-prostatic origin: A comparative study

2016

Journal Article

Prostate cancer grading: Recent developments and future directions

Delahunt, Brett, Egevad, Lars, Grignon, David J., Srigley, John R. and Samaratunga, Hema (2016). Prostate cancer grading: Recent developments and future directions. BJU International, 117 (S4), 7-8. doi: 10.1111/bju.13467

Prostate cancer grading: Recent developments and future directions

2016

Journal Article

Gleason and Fuhrman no longer make the grade

Delahunt, Brett, Egevad, Lars, Samaratunga, Hemamali, Martignoni, Guido, Nacey, John N. and Srigley, John R. (2016). Gleason and Fuhrman no longer make the grade. Histopathology, 68 (4), 475-481. doi: 10.1111/his.12803

Gleason and Fuhrman no longer make the grade

2016

Journal Article

Histologic prognostic markers for renal cell neoplasia

Delahunt, Brett, Samaratunga, Hemamali and Kenwright, Diane N. (2016). Histologic prognostic markers for renal cell neoplasia. Diagnostic Histopathology, 22 (2), 65-72. doi: 10.1016/j.mpdhp.2016.01.002

Histologic prognostic markers for renal cell neoplasia

2016

Conference Publication

Immunohistochemical expression of kidney injury molecule-1 Aids in the differentiation of chromophobe renal cell carcinoma and renal oncocytoma in an Australian cohort

Ng, Keng, Wood, Simon, Gobe, Glenda, Samaratunga, Hemamali, Morais, Christudas, Small, David, Oh, Seung, Del Vecchio, Sharon and Ellis, Robert (2016). Immunohistochemical expression of kidney injury molecule-1 Aids in the differentiation of chromophobe renal cell carcinoma and renal oncocytoma in an Australian cohort. 14th Urological Association of Asia Congress, Singapore, 20-24 July 2016. Richmond, VIC, Australia: Wiley-Blackwell.

Immunohistochemical expression of kidney injury molecule-1 Aids in the differentiation of chromophobe renal cell carcinoma and renal oncocytoma in an Australian cohort

2016

Conference Publication

Histopathological diagnosis of chromophobe renal cell carcinoma and renal oncocytoma: immunohistochemistry and multispectral imaging of cytokeratin 7, leptin and caveolin-1

Ng, N., Morais, C., Samaratunga, H., Gobe, G. and Wood, S. (2016). Histopathological diagnosis of chromophobe renal cell carcinoma and renal oncocytoma: immunohistochemistry and multispectral imaging of cytokeratin 7, leptin and caveolin-1. 69th Annual Scientific Meeting of the Urological Society of Australia and New Zealand, Gold Coast, QLD, Australia, 16-19 April 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/bju.13452

Histopathological diagnosis of chromophobe renal cell carcinoma and renal oncocytoma: immunohistochemistry and multispectral imaging of cytokeratin 7, leptin and caveolin-1

2016

Conference Publication

Prostatic fluid mRNA and microRNA biomarkers: an emerging paradigm for noninvasive diagnosis of prostate cancer

Roberts, Matthew J., Richards, R., Chow, C. W. K., Schirra, H., Buck, M., Selth, L. A., Doi, S. A., Samaratunga, H., Perry-Keene, J., Payton, D., Yaxley, J., Lavin, M. F. and Gardiner, R. A. (2016). Prostatic fluid mRNA and microRNA biomarkers: an emerging paradigm for noninvasive diagnosis of prostate cancer. ANZUP Annual Scientific Meeting, GU Cancer: Expanding our Horizons, Brisbane, QLD Australia, 10-12 July 2016. Chichester, West Sussex United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/ajco.12558

Prostatic fluid mRNA and microRNA biomarkers: an emerging paradigm for noninvasive diagnosis of prostate cancer

2016

Journal Article

Accuracy of prostate biopsies for predicting Gleason score in radical prostatectomy specimens: nationwide trends 2000-2012

Danneman, Daniela, Drevin, Linda, Delahunt, Brett, Samaratunga, Hemamali, Robinson, David, Bratt, Ola, Loeb, Stacy, Stattin, Par and Egevad, Lars (2016). Accuracy of prostate biopsies for predicting Gleason score in radical prostatectomy specimens: nationwide trends 2000-2012. BJU International, 119 (1), 50-56. doi: 10.1111/bju.13458

Accuracy of prostate biopsies for predicting Gleason score in radical prostatectomy specimens: nationwide trends 2000-2012

2016

Conference Publication

A new prostate-based biofluid for the detection of prostate cancer and diagnostic performance comparison using mRNA biomarkers

Roberts, M., Chow, C., Schirra, H., Richards, R., Buck, M., Doi, S., Samaratunga, H., Yaxley, J., Lavin, M. and Gardiner, R. (2016). A new prostate-based biofluid for the detection of prostate cancer and diagnostic performance comparison using mRNA biomarkers. 69th Annual Scientific Meeting of the Urological-Society-of-Australia-and-New Zealand, Gold Coast, Australia, 16-19 April 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. doi: 10.1111/bju.13452

A new prostate-based biofluid for the detection of prostate cancer and diagnostic performance comparison using mRNA biomarkers

2016

Journal Article

The 2014 international society of urological pathology (ISUP) consensus conference on gleason grading of prostatic carcinoma definition of grading patterns and proposal for a new grading system

Epstein, Jonathan I., Egevad, Lars, Amin, Mahul B., Delahunt, Brett, Srigley, John R., Humphrey, Peter A., Al-Hussain, Turki, Algaba, Ferran, Aron, Manju, Berman, David, Berney, Daniel, Brimo, Fadi, Cao, Dengfeng, Cheville, John, Clouston, David, Colecchia, Maurizio, Comperat, Eva, Da Cunha, Isabela Werneck, De Marzo, Angelo, Ertoy, Dilek, Fine, Samson, Foster, Christopher, Grignon, David, Gupta, Nilesh, Gupta, Ruta, Kench, James, Kristiansen, Glen, Kunju, Lakshmi, Leite, Katia Ramos Moreira ... The Grading Committee (2016). The 2014 international society of urological pathology (ISUP) consensus conference on gleason grading of prostatic carcinoma definition of grading patterns and proposal for a new grading system. American Journal of Surgical Pathology, 40 (2), 244-252. doi: 10.1097/PAS.0000000000000530

The 2014 international society of urological pathology (ISUP) consensus conference on gleason grading of prostatic carcinoma definition of grading patterns and proposal for a new grading system

2016

Conference Publication

Expression of S100 calcium binding protein A1 (S100A1) aids in the differentiation of renal cell carcinoma versus normal kidney tissue

Del Vecchio, S., Ng, K., Ellis, R., Samaratunga, H., Gobe, G. and Wood, S. (2016). Expression of S100 calcium binding protein A1 (S100A1) aids in the differentiation of renal cell carcinoma versus normal kidney tissue. The 15th Asian Pacific Congress of Nephrology (APCN) and 52nd ANZSN ASM, Perth, WA, Australia, 17–21 September 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12888

Expression of S100 calcium binding protein A1 (S100A1) aids in the differentiation of renal cell carcinoma versus normal kidney tissue

2016

Conference Publication

A Randomized Controlled Trial of Robotic Versus Open Radical Prostatectomy: Early Outcomes

Gardiner, Robert ('Frank'), Yaxley, John W., Coughlin, Geoffrey D., Chambers, Suzanne K., Occhipinti, Stefano, Samaratunga, Hema, Zaidlewicz, Leah, Dunglison, Nigel, Carter, Rob, Williams, Scott, Payton, Diane J., Perry-Keene, Joanna and Lavin, Martin F. (2016). A Randomized Controlled Trial of Robotic Versus Open Radical Prostatectomy: Early Outcomes. ANZUP Annual Scientific Meeting, GU Cancer: Expanding our Horizons, Brisbane, Australia, 10-12 July 2016. West Sussex, United Kingdom: Wiley. doi: 10.1111/ajco.12557

A Randomized Controlled Trial of Robotic Versus Open Radical Prostatectomy: Early Outcomes

2016

Journal Article

Multifocal primary neoplasms in kidney allografts: evaluation of two cases

Ellis, Robert J., Ng, Keng Lim, Samaratunga, Hemamali, Del Vecchio, Sharon J., Wood, Simon T. and Gobe, Glenda C. (2016). Multifocal primary neoplasms in kidney allografts: evaluation of two cases. Journal of Kidney Cancer and VHL, 3 (2), 14-22. doi: 10.15586/jkcvhl.2016.53

Multifocal primary neoplasms in kidney allografts: evaluation of two cases

2015

Journal Article

Cancer stem cell markers in prostate cancer: An immunohistochemical study of ALDH1, SOX2 and EZH2

Matsika, Admire, Srinivasan, Bhuvana, Day, Christopher, Mader, Sabina Ann, Kiernan, Deirdre Margaret, Broomfield, Amy, Fu, Jinlin, Hooper, John D., Kench, James G. and Samaratunga, Hemamali (2015). Cancer stem cell markers in prostate cancer: An immunohistochemical study of ALDH1, SOX2 and EZH2. Pathology, 47 (7), 622-628. doi: 10.1097/PAT.0000000000000325

Cancer stem cell markers in prostate cancer: An immunohistochemical study of ALDH1, SOX2 and EZH2

2015

Journal Article

Magnitude of PD-1, PD-L1 and T lymphocyte expression on tissue from castration-resistant prostate adenocarcinoma: an exploratory analysis

Massari, Francesco, Ciccarese, Chiara, Calio, Anna, Munari, Enrico, Cima, Luca, Porcaro, Antonio Benito, Novella, Giovanni, Artibani, Walter, Sava, Teodoro, Eccher, Albino, Ghimenton, Claudio, Bertoldo, Francesco, Scarpa, Aldo, Sperandio, Nicola, Porta, Camillo, Bronte, Vincenzo, Chilosi, Marco, Bogina, Giuseppe, Zamboni, Giuseppe, Tortora, Giampaolo, Samaratunga, Hemamali, Martignoni, Guido and Brunelli, Matteo (2015). Magnitude of PD-1, PD-L1 and T lymphocyte expression on tissue from castration-resistant prostate adenocarcinoma: an exploratory analysis. Targeted Oncology, 11 (3), 1-7. doi: 10.1007/s11523-015-0396-3

Magnitude of PD-1, PD-L1 and T lymphocyte expression on tissue from castration-resistant prostate adenocarcinoma: an exploratory analysis

2015

Journal Article

Is transperineal prostate biopsy more accurate than transrectal biopsy in determining final Gleason score and clinical risk category? A comparative analysis

Scott, Susan, Samaratunga, Hemamali, Chabert, Charles, Breckenridge, Michelle and Gianduzzo, Troy (2015). Is transperineal prostate biopsy more accurate than transrectal biopsy in determining final Gleason score and clinical risk category? A comparative analysis. BJU International, 116 (S3), 26-30. doi: 10.1111/bju.13165

Is transperineal prostate biopsy more accurate than transrectal biopsy in determining final Gleason score and clinical risk category? A comparative analysis

2015

Journal Article

The prognostic significance of the 2014 International Society of Urological Pathology (ISUP) grading system for prostate cancer

Samaratunga, Hemamali, Delahunt, Brett, Gianduzzo, Troy, Coughlin, Geoff, Duffy, David, LeFevre, Ian, Johannsen, Shulammite, Egevad, Lars and Yaxley, John (2015). The prognostic significance of the 2014 International Society of Urological Pathology (ISUP) grading system for prostate cancer. Pathology, 47 (6), 515-519. doi: 10.1097/PAT.0000000000000315

The prognostic significance of the 2014 International Society of Urological Pathology (ISUP) grading system for prostate cancer

2015

Journal Article

Diagnostic performance of expression of PCA3, Hepsin and miR biomarkers inejaculate in combination with serum PSA for the detection of prostate cancer

Roberts, Matthew J., Chow, Clement W., Schirra, Horst J., Richards, Renee, Buck, Marion, Selth, Luke A., Doi, Suhail A. R., Samaratunga, Hema, Perry-Keene, Joanna, Payton, Diane, Yaxley, John, Lavin, Martin F. and Gardiner, Robert A. (2015). Diagnostic performance of expression of PCA3, Hepsin and miR biomarkers inejaculate in combination with serum PSA for the detection of prostate cancer. Prostate, 75 (5), 539-549. doi: 10.1002/pros.22942

Diagnostic performance of expression of PCA3, Hepsin and miR biomarkers inejaculate in combination with serum PSA for the detection of prostate cancer

Supervision

Availability

Professor Hemamali Samaratunga is:
Available for supervision

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Media

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