
Overview
Background
Associate Professor Paul Griffin is the Director of Infectious Diseases at Mater Health Services in Brisbane and Associate Professor of Medicine at the University of Queensland Medical School. He has fellowships in Infectious Diseases from the Royal Australasian College of Physicians, in Clinical Microbiology from the Royal College of Pathologists of Australasia and from the Australasian College of Tropical Medicine.
Paul is the Principal Investigator and Medical Director at Nucleus Network, a specialized contract research organisation specializing in early and late phase trials in infectious diseases where he has been the principal investigator on in excess of 125 clinical trials, predominantly in Infectious Diseases including novel vaccines and Malaria human challenge studies. This includes 8 vaccines for COVID-19 and a number of COVID-19 therapies.
As a Clinical Microbiologist, he maintains an active interest in diagnostic microbiology with a focus on clinical applications of faecal microbiome metagenomic sequencing.
In addition to a teaching role at the University of Queensland, Paul is also the chair of the Advanced Training Committee in Infectious Diseases with the Royal Australasian College of Physicians, the committee that oversees the training of Infectious Diseases specialists in Australia.
Finally, as a director and scientific advisory board member of the immunisation coalition, Paul has an active interest in vaccine education and advocacy and has become a trusted media authority and spokesperson across the nation during the COVID-19 pandemic.
Availability
- Professor Paul Griffin is:
- Available for supervision
- Media expert
Fields of research
Research impacts
While performing vital clinical and research duties, he has also devoted time to inform, educate and reassure the community via a wide range of media appearances. He has featured regularly on prominent Australian programs across television, radio, print and online including The Project, Sunrise, Today Show, A Current Affair, and internationally including Canada’s CTV and the BBC.
Works
Search Professor Paul Griffin’s works on UQ eSpace
2016
Journal Article
A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study
McCarthy, James S., Ruckle, Thomas, Djeriou, Elhadj, Cantalloube, Cathy, Ter-Minassian, Daniel, Baker, Mark, O'Rourke, Peter, Griffin, Paul, Marquart, Louise, van Huijsduijnen, Rob Hooft and Mohrle, Jorg J. (2016). A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study. Malaria Journal, 15 (469) 469, 469. doi: 10.1186/s12936-016-1511-3
2016
Journal Article
Infectivity of Plasmodium falciparum in malaria-naive individuals is related to knob expression and cytoadherence of the parasite
Stanisic, Danielle I., Gerrard, John, Fink, James, Griffin, Paul M., Liu, Xue Q., Sundac, Lana, Sekuloski, Silvana, Rodriguez, Ingrid B., Pingnet, Jolien, Yang, Yuedong, Zhou, Yaoqi, Trenholme, Katharine R., Wang, Claire Y. T., Hackett, Hazel, Chan, Jo-Anne A., Langer, Christine, Hanssen, Eric, Hoffman, Stephen L., Beeson, James G., McCarthy, James S. and Good, Michael F. (2016). Infectivity of Plasmodium falciparum in malaria-naive individuals is related to knob expression and cytoadherence of the parasite. Infection and Immunity, 84 (9), 2689-2696. doi: 10.1128/IAI.00414-16
2016
Journal Article
Efficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers
McCarthy, James S., Baker, Mark, O'Rourke, Peter, Marquart, Louise, Griffin, Paul, van huijsduijnen, Rob Hooft and Mohrle, Jorg J. (2016). Efficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers. Journal of Antimicrobial Chemotherapy, 71 (9), 2620-2627. doi: 10.1093/jac/dkw174
2016
Journal Article
An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1
Dutton, Julie L., Woo, Wai-Ping, Chandra, Janin, Xu, Yan, Li, Bo, Finlayson, Neil, Griffin, Paul and Frazer, Ian H. (2016). An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1. Human Vaccines and Immunotherapeutics, 12 (12), 3079-3088. doi: 10.1080/21645515.2016.1221872
2016
Journal Article
Piperaquine monotherapy of drug-susceptible Plasmodium falciparum infection results in rapid clearance of Parasitemia but is followed by the appearance of Gametocytemia
Pasay, Cielo J., Rockett, Rebecca, Sekuloski, Silvana, Griffin, Paul, Marquart, Louise, Peatey, Christopher, Wang, Claire Y. T., O'Rourke, Peter, Elliott, Suzanne, Baker, Mark, Möhrle, Jörg J. and McCarthy, James S. (2016). Piperaquine monotherapy of drug-susceptible Plasmodium falciparum infection results in rapid clearance of Parasitemia but is followed by the appearance of Gametocytemia. Journal of Infectious Diseases, 214 (1), 105-113. doi: 10.1093/infdis/jiw128
2016
Journal Article
Linking murine and human Plasmodium falciparum challenge models in a translational path for antimalarial drug development
McCarthy, James S., Marquart, Louise, Sekuloski, Silvana, Trenholme, Katherine, Elliott, Suzanne, Griffin, Paul, Rockett, Rebecca, O'Rourke, Peter, Sloots, Theo, Angulo-Barturen, Inigo, Ferrer, Santiago, Jimenez-Diaz, Maria Belen, Martinez, Maria-Santos, van Huijsduijnen, Rob Hoof, Duparc, Stephan, Leroy, Didier, Wells, Timothy N. C., Baker, Mark and Mohrle, Jorg J. (2016). Linking murine and human Plasmodium falciparum challenge models in a translational path for antimalarial drug development. Antimicrobial Agents and Chemotherapy, 60 (6), 3669-3675. doi: 10.1128/AAC.02883-15
2016
Conference Publication
First-in-human phase 1 safety study of BLZ-100 in subjects with skin cancer
Spelman, L., Johnston, J., Prow, T., Yamada, M., Griffin, P., Wood, D. and Miller, D. (2016). First-in-human phase 1 safety study of BLZ-100 in subjects with skin cancer. Australasian College of Dermatologists 49th Annual Scientific Meeting, Perth, Australia, 14–17 May 2016. HOBOKEN: WILEY-BLACKWELL.
2015
Journal Article
Acute vancomycin-resistant enterococcal bacteraemia outbreak analysis in haematology patients: a case-control study
Gassiep, Ian, Armstrong, Mark, Van Havre, Zoe, Schlebusch, Sanmarie, McCormack, Joseph and Griffin, Paul (2015). Acute vancomycin-resistant enterococcal bacteraemia outbreak analysis in haematology patients: a case-control study. Healthcare Infection, 20 (4), 115-123. doi: 10.1071/HI15013
2015
Journal Article
Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609(Cipargamin) and Piperaquine
Stein, Daniel S, Jain, Jay Prakash, Kangas, Michael, Lefèvre, Gilbert, Machineni, Surendra, Griffin, Paul and Lickliterf, Jason (2015). Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609(Cipargamin) and Piperaquine. Antimicrobial Agents and Chemotherapy, 59 (6), 3493-3500. doi: 10.1128/AAC.00340-15
2014
Journal Article
Delusions of disseminated fungosis
Gassiep, Ian and Griffin, Paul Matthew (2014). Delusions of disseminated fungosis. Case Reports in Infectious Diseases, 2014 (458028), 1-3. doi: 10.1155/2014/458028
2014
Journal Article
Vancomycin-induced linear IgA with mucosal and ocular involvement: a case report
Dang, Lily V., Byrom, Lisa, Muir, Jim and Griffin, Paul M. (2014). Vancomycin-induced linear IgA with mucosal and ocular involvement: a case report. Infectious Diseases in Clinical Practice, 22 (5), e119-e121. doi: 10.1097/IPC.0000000000000182
2014
Journal Article
Fasting increases serum bilirubin levels in clinically normal, healthy males but not females: a retrospective study from phase I clinical trial participants
Griffin, Paul M., Elliott, Suzanne L. and Manton, Kerry J. (2014). Fasting increases serum bilirubin levels in clinically normal, healthy males but not females: a retrospective study from phase I clinical trial participants. Journal of Clinical Pathology, 67 (6), 529-534. doi: 10.1136/jclinpath-2013-202155
2014
Book Chapter
Menangle
Griffin, P. M. (2014). Menangle. Infectious Disease and Antimicrobial Agents. (pp. 1-1) Pittsburgh, PA, United States: Antimicrobe.
2014
Book Chapter
Barmah Forest Virus
Griffin, Paul (2014). Barmah Forest Virus. Infectious Disease and Antimicrobial Agents. (pp. 1-1) edited by Victor L. Yu, Rainer Weber and Didier Raoult. Pittsburgh, PA, USA: Antimicrobe.
2014
Book Chapter
Ross River Virus
Griffin, Paul (2014). Ross River Virus. Infectious Disease and Antimicrobial Agents. (pp. 1-1) Pittsburgh, PA, United States: Antimicrobe.
2014
Journal Article
Maldi in infection control (VRE)
Griffin, Paul (2014). Maldi in infection control (VRE). Pathology, 46, S45. doi: 10.1097/01.pat.0000443496.32732.1d
2014
Book Chapter
Australian Bat Lyssavirus
Griffin, Paul (2014). Australian Bat Lyssavirus. Infectious Disease and Antimicrobial Agents. (pp. 1-1) edited by Victor L. Yu, Rainer Weber and Didier Raoult. Pittsburgh, PA, USA: Antimicrobe.
2014
Conference Publication
A phase 1 evaluation of the pharmacokinetic/pharmacodynamics interaction of the antimalarial agent KAE609 and piperaquine (PPQ)
Stein, Daniel, Jain, Jay Prakash, Lickliter, Jason, Kangas, Michael, Machineri, Surendra and Griffin, Paul (2014). A phase 1 evaluation of the pharmacokinetic/pharmacodynamics interaction of the antimalarial agent KAE609 and piperaquine (PPQ). Challanges in malaria research: Core science and innovation, Oxford, United Kingdom, 22-24 September 2014. London, United Kingdom: BioMed Central. doi: 10.1186/1475-2875-13-S1-P85
2013
Journal Article
Experimentally induced blood-stage plasmodium vivax infection in healthy volunteers
McCarthy, James S., Griffin, Paul M., Sekuloski, Silvana, Bright, A. Taylor, Rockett, Rebecca, Looke, David, Elliott, Suzanne, Whiley, David, Sloots, Theo, Winzeler, Elizabeth A. and Trenholme, Katharine R. (2013). Experimentally induced blood-stage plasmodium vivax infection in healthy volunteers. Journal of Infectious Diseases, 208 (10), 1688-1694. doi: 10.1093/infdis/jit394
2013
Conference Publication
Rapid Identification of Vancomycin Resistant Enterococci with Maldi-Tof Mass Spectrometry
Griffin, Paul, Price, Gareth, Hamilton, Brett, Schooneveldt, Jacqueline, Urbanski, Tess, Schlebusch, Sanmarie and Venter, Deon (2013). Rapid Identification of Vancomycin Resistant Enterococci with Maldi-Tof Mass Spectrometry. The Royal Australasian College of Physicians Future Directions in Health Congress 2013 (RACP), Perth, WA Australia, 26-29 May 2013. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/imj.12153
Funding
Past funding
Supervision
Availability
- Professor Paul Griffin is:
- Available for supervision
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Media
Enquiries
Contact Professor Paul Griffin directly for media enquiries about:
- COVID-19
- Infectious Diseases
- microbiology
- Vaccines
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