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Decoding the spatiotemporal control of DNA replication and repair (2021-2023)

Abstract

DNA replication is the fundamental mechanism of genetic inheritance and essential for all cellular life. This project aims to inform our understanding of how human cells coordinate the DNA replication machinery in time and space to accurately copy the human genome. By applying multiple innovative approaches and employing an interdisciplinary research team, this project is anticipated to generate new knowledge that explains how the human genome is replicated. This knowledge is expected to generate research publications of high quality and provide economic benefits, such as unlocking new potentially patentable DNA technologies.

Experts

Dr Mathew Jones

Senior Lecturer
School of Chemistry and Molecular Biosciences
Faculty of Science
Mathew Jones
Mathew Jones

Professor Paul Clarke

Affiliate of Centre for Extracellular Vesicle Nanomedicine
Centre for Extracellular Vesicle Nanomedicine
Faculty of Health, Medicine and Behavioural Sciences
Honorary Professor
Faculty of Health, Medicine and Behavioural Sciences
Paul Clarke
Paul Clarke