Terahertz virtual skin biopsy: Quantum cascade laser imaging of early melanoma (2025-2026)
Abstract
The aim of this project is to evaluate our THz quantum imager for in-vivo melanoma detection, currently at TRL4. The imaging will be conducted at two distinct THz frequencies to demonstrate contrast between healthy and diseased tissues, targeting melanoma biomarkers and assessing disease progression. A 100-person trial will be conducted with participants who have lesions suspected of melanoma. The lesions will be imaged using the THz quantum imager and compared with gold standard histopathology, positioning the device at TRL5 at project end. This device has potential to revolutionize early melanoma diagnosis, reduce overdiagnosis, improve patient outcomes, and alleviate the burden of melanoma on the Australian healthcare system.