A platform for in situ structural biology (ARC LIEF administered by Monash University) (2025-2026)
Abstract
This project aims to establish an Australian facility for in situ structural biology. The Arctis cryo-plasma focused ion beam will enable cryo-electron microscopy on a large range of samples from bacteria, plants, animal cells, tissues and organs to soft materials. This project expects to reveal new structural information in situ generating knowledge in the fields of microbiology, cell and developmental biology and in bioengineering and materials science. Expected outcomes are fundamental discoveries, training opportunities, international collaborations, and high impact publications. This project should provide significant benefits through underpinning innovation in renewal energy generation and storage, drug delivery, and nanotechnology.
