Combating Antibiotic Resistance by Antibiotic Potentiation (2026-2029)
Abstract
This project will study an antimicrobial combination treatment discovered by industry partner Neolixir Ltd (Lixa), using a novel compound ('potentiator') that helps existing antibiotics work better. We will apply genetic and molecular biology tools to understand how the combination kills bacteria. We will investigate what combinations work best, and against what pathogens. This research is critical to understand the most favorable commercial opportunities to pursue in the agricultural, environmental and human health sectors. The project is expected to lead to significant benefits, including high impact publications and new products for industry partner Lixa that are able to overcome the global threat posed by antibiotic resistance.
