Generation of peptidomimetic surfaces for biomaterials applications (2008-2010)
Abstract
The successful integration of biomedical implants into the body requires materials surfaces that have favourable interactions with cells, as well as appropriate bulk mechanical properties for the desired application. This project will develop innovative methods for the surface modification of biomaterials with tuneable peptide-like molecular structures, with the aim of promoting favourable interactions between the surface and cells, to reduce the rejection of biomaterials from the body. The initial targeted application of materials with these novel surfaces is in the treatment of preventable blindness and severe visual impairment, although this technology can be applied to almost any biomaterial application.