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2022

Journal Article

Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption

Janowicz, Phillip W., Houston, Zachary H., Bunt, Jens, Fletcher, Nicholas L., Bell, Craig A., Cowin, Gary, Howard, Christopher B., Taslima, Dewan, Westra van Holthe, Nicholas, Prior, Amber, Soh, Vanessa, Ghosh, Saikat, Humphries, James, Huda, Pie, Mahler, Stephen M., Richards, Linda J. and Thurecht, Kristofer J. (2022). Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption. Biomaterials, 283 121416, 121416. doi: 10.1016/j.biomaterials.2022.121416

Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption

2022

Journal Article

Simple synthetic route to a self-assembling enzyme-inspired transesterification catalysts

Kumar, Ashwani, Nothling, Mitchell David, Aitken, Heather M., Xiao, Zeyun, Lam, Mathew, Bell, Craig, O'Mara, Megan and Connal, Luke Andrew (2022). Simple synthetic route to a self-assembling enzyme-inspired transesterification catalysts. Catalysis Science and Technology, 12 (22), 6655-6659. doi: 10.1039/d2cy00744d

Simple synthetic route to a self-assembling enzyme-inspired transesterification catalysts

2021

Journal Article

Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering

Wandel, Mary Beth, Bell, Craig A., Yu, Jiayi, Arno, Maria C., Dreger, Nathan Z., Hsu, Yen-Hao, Pitto-Barry, Anaïs, Worch, Joshua C., Dove, Andrew P. and Becker, Matthew L. (2021). Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering. Nature Communications, 12 (1) 446. doi: 10.1038/s41467-020-20610-5

Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering

2021

Journal Article

Optimisation of alendronate conjugation to polyethylene glycol for functionalisation of biopolymers and nanoparticles

Poli, Hamish, Mushtaq, Asim, Bell, Craig A., McGeary, Ross P., Grøndahl, Lisbeth and A, Anitha (2021). Optimisation of alendronate conjugation to polyethylene glycol for functionalisation of biopolymers and nanoparticles. European Polymer Journal, 155 110571, 110571. doi: 10.1016/j.eurpolymj.2021.110571

Optimisation of alendronate conjugation to polyethylene glycol for functionalisation of biopolymers and nanoparticles

2021

Journal Article

Cyanine-5-driven behaviours of hyperbranched polymers designed for therapeutic delivery are cell-type specific and correlated with polar lipid distribution in membranes

Simpson, Joshua D., Currin-Ross, Denni L., Ediriweera, Gayathri R., Schirra, Horst Joachim, Fletcher, Nicholas L., Bell, Craig A., Arno, Maria C. and Thurecht, Kristofer J. (2021). Cyanine-5-driven behaviours of hyperbranched polymers designed for therapeutic delivery are cell-type specific and correlated with polar lipid distribution in membranes. Nanomaterials, 11 (7) 1745, 1-18. doi: 10.3390/nano11071745

Cyanine-5-driven behaviours of hyperbranched polymers designed for therapeutic delivery are cell-type specific and correlated with polar lipid distribution in membranes

2021

Journal Article

Poly(2-ethyl-2-oxazoline) bottlebrushes: How nanomaterial dimensions can influence biological interactions

Pizzi, David, Mahmoud, Ayaat M., Klein, Tobias, Morrow, Joshua P., Humphries, James, Houston, Zachary H., Fletcher, Nicholas L., Bell, Craig A., Thurecht, Kristofer J. and Kempe, Kristian (2021). Poly(2-ethyl-2-oxazoline) bottlebrushes: How nanomaterial dimensions can influence biological interactions. European Polymer Journal, 151 110447, 1-9. doi: 10.1016/j.eurpolymj.2021.110447

Poly(2-ethyl-2-oxazoline) bottlebrushes: How nanomaterial dimensions can influence biological interactions

2021

Other Outputs

Biomimetic synthetic rubber and methods for controlling its physical properties through backbone double bond stereochemistry by monomer selection and end group modification

Becker, Matthew L., Dove, Andrew P., Truong, Vinh X., Bell, Craig A., Barker, Ian A. and Yu, Jiayi (2021). Biomimetic synthetic rubber and methods for controlling its physical properties through backbone double bond stereochemistry by monomer selection and end group modification. US10968303.

Biomimetic synthetic rubber and methods for controlling its physical properties through backbone double bond stereochemistry by monomer selection and end group modification

2021

Journal Article

Thermally-induced hyperbranching of bromine-containing polyesters by insertion of in situ generated chain-end carbenes dagger

Bexis, Panagiotis, Arno, Maria C., Bell, Craig A., Thomas, Anthony W. and Dove, Andrew P. (2021). Thermally-induced hyperbranching of bromine-containing polyesters by insertion of in situ generated chain-end carbenes dagger. Chemical Communications, 57 (35), 4275-4278. doi: 10.1039/d1cc00821h

Thermally-induced hyperbranching of bromine-containing polyesters by insertion of in situ generated chain-end carbenes dagger

2021

Journal Article

Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models

Simpson, Joshua D., Monteiro, Patrícia F., Ediriweera, Gayathri R., Prior, Amber R., Sonderegger, Stefan E., Bell, Craig A., Fletcher, Nicholas L., Alexander, Cameron and Thurecht, Kristofer J. (2021). Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models. ACS Applied Bio Materials, 4 (3) acsabm.0c01616, 2675-2685. doi: 10.1021/acsabm.0c01616

Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models

2021

Journal Article

Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study

Kane, Alexandra M., Liu, Cheng, Akhter, Dewan T., McKeone, Diane M., Bell, Craig A., Thurecht, Kristofer J., Leggett, Barbara A. and Whitehall, Vicki L. J. (2021). Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study. Digestive Diseases and Sciences, 66 (12), 4326-4332. doi: 10.1007/s10620-020-06752-y

Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study

2021

Journal Article

Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract

dos Santos, Aline Martins, Meneguin, Andréia Bagliotti, Akhter, Dewan Taslima, Fletcher, Nicholas, Houston, Zachary H., Bell, Craig, Thurecht, Kristofer J. and Gremião, Maria Palmira Daflon (2021). Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract. European Journal of Pharmaceutics and Biopharmaceutics, 158, 371-378. doi: 10.1016/j.ejpb.2020.12.004

Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract

2020

Journal Article

Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acids

Sivaram, Amal J., Wardiana, Andri, Preethi, S. S. Hema, Fuchs, Adrian V., Howard, Christopher B., Fletcher, Nicholas L., Bell, Craig A. and Thurecht, Kristofer J. (2020). Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acids. Macromolecular Rapid Communications, 41 (21) 2000294, e2000294. doi: 10.1002/marc.202000294

Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acids

2020

Journal Article

Person-specific biomolecular coronas modulate nanoparticle interactions with immune cells in human blood

Ju, Yi, Kelly, Hannah G., Dagley, Laura F., Reynaldi, Arnold, Schlub, Timothy E., Spall, Sukhdeep K., Bell, Craig A., Cui, Jiwei, Mitchell, Andrew J., Lin, Zhixing, Wheatley, Adam K., Thurecht, Kristofer J., Davenport, Miles P., Webb, Andrew I., Caruso, Frank and Kent, Stephen J. (2020). Person-specific biomolecular coronas modulate nanoparticle interactions with immune cells in human blood. ACS Nano, 14 (11) acsnano.0c06679, 15723-15737. doi: 10.1021/acsnano.0c06679

Person-specific biomolecular coronas modulate nanoparticle interactions with immune cells in human blood

2020

Journal Article

Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting

Sivaram, Amal J., Wardiana, Andri, Alcantara, Sheilajen, Sonderegger, Stefan E., Fletcher, Nicholas L., Houston, Zachary H., Howard, Christopher B., Mahler, Stephen M., Alexander, Cameron, Kent, Stephen J., Bell, Craig A. and Thurecht, Kristofer J. (2020). Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting. ACS Nano, 14 (10) acsnano.0c06033, 13739-13753. doi: 10.1021/acsnano.0c06033

Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting

2020

Journal Article

Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A structure–activity comparison of biodistribution

Humphries, James, Pizzi, David, Sonderegger, Stefan E., Fletcher, Nicholas L., Houston, Zachary H., Bell, Craig A., Kempe, Kristian and Thurecht, Kristofer J. (2020). Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A structure–activity comparison of biodistribution. Biomacromolecules, 21 (8) acs.biomac.0c00765, 3318-3331. doi: 10.1021/acs.biomac.0c00765

Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A structure–activity comparison of biodistribution

2020

Journal Article

Tuning of the aggregation behavior of fluorinated polymeric nanoparticles for improved therapeutic efficacy

Zhang, Cheng, Liu, Tianqing, Wang, Wenqian, Bell, Craig A., Han, Yanxiao, Fu, Changkui, Peng, Hui, Tan, Xiao, Král, Petr, Gaus, Katharina, Gooding, J. Justin and Whittaker, Andrew K. (2020). Tuning of the aggregation behavior of fluorinated polymeric nanoparticles for improved therapeutic efficacy. ACS Nano, 14 (6) acsnano.0c02954, 7425-7434. doi: 10.1021/acsnano.0c02954

Tuning of the aggregation behavior of fluorinated polymeric nanoparticles for improved therapeutic efficacy

2020

Conference Publication

Canine PET/CT imaging with 64Cu-nanomedicines

Daniel, Sarah, Houston, Zachary, Fletcher, Nicholas, Bell, Craig, Atcheson, Nicole, Al-Najjar, Aiman, Howard, Christopher, Mahler, Stephen, Straw, Rod and Thurecht, Kristofer (2020). Canine PET/CT imaging with 64Cu-nanomedicines. SNMMI Annual Meeting, Online, 11-14 July, 2020. Reston, VA, United States: Society of Nuclear Medicine.

Canine PET/CT imaging with 64Cu-nanomedicines

2020

Journal Article

Oral delivery of multicompartment nanomedicines for colorectal cancer therapeutics: combining loco-regional delivery with cell-target specificity

Akhter, Dewan T., Simpson, Joshua D., Fletcher, Nicholas L., Houston, Zachary H., Fuchs, Adrian V., Bell, Craig A. and Thurecht, Kristofer J. (2020). Oral delivery of multicompartment nanomedicines for colorectal cancer therapeutics: combining loco-regional delivery with cell-target specificity. Advanced Therapeutics, 3 (2) 1900171, 1-13. doi: 10.1002/adtp.201900171

Oral delivery of multicompartment nanomedicines for colorectal cancer therapeutics: combining loco-regional delivery with cell-target specificity

2020

Journal Article

Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery

Ediriweera, Gayathri R., Simpson, Joshua D., Fuchs, Adrian V., Venkatachalam, Taracad K., Van De Walle, Matthias, Howard, Christopher B., Mahler, Stephen M., Blinco, James P., Fletcher, Nicholas L., Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2020). Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery. Chemical Science, 11 (12), 3268-3280. doi: 10.1039/d0sc00078g

Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery

2019

Journal Article

Poly(2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures

Pizzi, David, Humphries, James, Morrow, Joshua P., Fletcher, Nicholas L., Bell, Craig A., Thurecht, Kristofer J. and Kempe, Kristian (2019). Poly(2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures. European Polymer Journal, 121 109258, 109258. doi: 10.1016/j.eurpolymj.2019.109258

Poly(2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures