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2015

Conference Publication

Synthesising and characterising new ivermectin analogues targeting ligand-gated chloride channels

Islam, R., Xiao, X., Capon, R. and Lynch, J. (2015). Synthesising and characterising new ivermectin analogues targeting ligand-gated chloride channels. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13188

Synthesising and characterising new ivermectin analogues targeting ligand-gated chloride channels

2015

Conference Publication

Viridicatumtoxins: Exploring structural diversity and antibiotic properties

Shang, Z., Salim, A. A., Khalil, Z. G., Quezada, M., Bernhardt, P. V. and Capon, R. J. (2015). Viridicatumtoxins: Exploring structural diversity and antibiotic properties. Annual Meeting of the American-Society-of-Pharmacognosy, Copper Mountain, CO, United States, 25-29 July 2015. Stuttgart, Germany: Georg Thieme. doi: 10.1055/s-0035-1556338

Viridicatumtoxins: Exploring structural diversity and antibiotic properties

2015

Conference Publication

New small molecule analgesics that target the ALPHA3 glycine receptor

Lynch, J., Talwar, S., Xiao, X., Balansa, W., Islam, R., Fontaine, F., Piggott, A., Zhang, H., Webb, T., Gilbert, D., Vaughan, C. and Capon, R. (2015). New small molecule analgesics that target the ALPHA3 glycine receptor. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13185

New small molecule analgesics that target the ALPHA3 glycine receptor

2015

Journal Article

Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains

Azmi, Fazren, Elliott, Alysha G., Khalil, Zeinab G., Hussein, Waleed M., Kavanagh, Angela, Huang, Johnny X., Quezada, Michelle, Blaskovich, Mark A. T., Capon, Robert J., Cooper, Matthew A., Skwarczynski, Mariusz and Toth, Istvan (2015). Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains. Nanomedicine, 10 (22), 3359-3371. doi: 10.2217/nnm.15.137

Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains

2014

Journal Article

Isolation and synthesis of N-acyladenine and adenosine alkaloids from a southern Australian marine sponge, Phoriospongia sp.

Farrugia, Michelle, Trotter, Nicholas, Vijayasarathy, Soumini, Salim, Angele A., Khalil, Zeinab G., Lacey, Ernest and Capon, Robert J. (2014). Isolation and synthesis of N-acyladenine and adenosine alkaloids from a southern Australian marine sponge, Phoriospongia sp.. Tetrahedron Letters, 55 (43), 5902-5904. doi: 10.1016/j.tetlet.2014.08.116

Isolation and synthesis of N-acyladenine and adenosine alkaloids from a southern Australian marine sponge, Phoriospongia sp.

2014

Journal Article

Rare Streptomyces N-formyl amino-salicylamides inhibit oncogenic K-Ras

Salim, Angela A., Cho, Kwang-Jin, Tan, Lingxiao, Quezada, Michelle, Lacey, Ernest, Hancock, John F. and Capon, Robert J. (2014). Rare Streptomyces N-formyl amino-salicylamides inhibit oncogenic K-Ras. Organic Letters, 16 (19), 5036-5039. doi: 10.1021/ol502376e

Rare Streptomyces N-formyl amino-salicylamides inhibit oncogenic K-Ras

2014

Journal Article

Wollamides: antimycobacterial cyclic hexapeptides from an Australian soil Streptomyces

Khalil, Zeinab G., Salim, Angela A., Lacey, Ernest, Blumenthal, Antje and Capon, Robert J. (2014). Wollamides: antimycobacterial cyclic hexapeptides from an Australian soil Streptomyces. Organic Letters, 16 (19), 5120-5123. doi: 10.1021/ol502472c

Wollamides: antimycobacterial cyclic hexapeptides from an Australian soil Streptomyces

2014

Journal Article

Shornephine A: structure, chemical stability, and P-Glycoprotein inhibitory properties of a rare Diketomorpholine from an Australian marine-derived Aspergillus sp.

Khalil, Zeinab G., Huang, Xiao-cong, Raju, Ritesh, Piggott, Andrew M. and Capon, Robert J. (2014). Shornephine A: structure, chemical stability, and P-Glycoprotein inhibitory properties of a rare Diketomorpholine from an Australian marine-derived Aspergillus sp.. Journal of Organic Chemistry, 79 (18), 8700-8705. doi: 10.1021/jo501501z

Shornephine A: structure, chemical stability, and P-Glycoprotein inhibitory properties of a rare Diketomorpholine from an Australian marine-derived Aspergillus sp.

2014

Journal Article

Rare Streptomyces sp. polyketides as modulators of K-Ras localisation

Salim, Angela A., Xiao, Xue, Cho, Kwang-Jin, Piggott, Andrew M., Lacey, Ernest, Hancock, John F. and Capon, Robert J. (2014). Rare Streptomyces sp. polyketides as modulators of K-Ras localisation. Organic and Biomolecular Chemistry, 12 (27), 4872-4878. doi: 10.1039/c4ob00745j

Rare Streptomyces sp. polyketides as modulators of K-Ras localisation

2014

Journal Article

Lamellarin O, a pyrrole alkaloid from an Australian marine sponge, Ianthella sp., reverses BCRP mediated drug resistance in cancer cells

Huang, Xiao-Cong, Xiao, Xue, Zhang, Yun-Kai, Talele, Tanaji T., Salim, Angela A., Chen, Zhe-Sheng and Capon, Robert J. (2014). Lamellarin O, a pyrrole alkaloid from an Australian marine sponge, Ianthella sp., reverses BCRP mediated drug resistance in cancer cells. Marine Drugs, 12 (7), 3818-3837. doi: 10.3390/md12073818

Lamellarin O, a pyrrole alkaloid from an Australian marine sponge, Ianthella sp., reverses BCRP mediated drug resistance in cancer cells

2014

Journal Article

Heronapyrrole D: a case of co-inspiration of natural product biosynthesis, total synthesis and biodiscovery

Schmidt, Jens, Khalil, Zeinab, Capon, Robert J. and Stark, Christian B. W. (2014). Heronapyrrole D: a case of co-inspiration of natural product biosynthesis, total synthesis and biodiscovery. Beilstein Journal of Organic Chemistry, 10 (1), 1228-1232. doi: 10.3762/bjoc.10.121

Heronapyrrole D: a case of co-inspiration of natural product biosynthesis, total synthesis and biodiscovery

2014

Journal Article

Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244)

Raju, Ritesh, Khalil, Zeinab G., Piggott, Andrew M., Blumenthal, Antje, Gardiner, Donald L., Skinner-Adams, Tina S. and Capon, Robert J. (2014). Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244). Organic Letters, 16 (6), 1716-1719. doi: 10.1021/ol5003913

Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244)

2014

Journal Article

Callyspongisines A-D: Bromopyrrole alkaloids from an Australian marine sponge, Callyspongia sp.

Plisson,Fabien, Prasad, Pritesh, Xiao, Xue, Piggott, Andrew M., Huang, Xiao-cong, Khalil, Zeinab and Capon, Robert J. (2014). Callyspongisines A-D: Bromopyrrole alkaloids from an Australian marine sponge, Callyspongia sp.. Organic and Biomolecular Chemistry, 12 (10), 1579-1584. doi: 10.1039/c4ob00091a

Callyspongisines A-D: Bromopyrrole alkaloids from an Australian marine sponge, Callyspongia sp.

2014

Journal Article

Total synthesis of heronapyrrole C

Ding, Xiao-Bo, Furkert, Daniel P., Capon, Robert J. and Brimble, Margaret A. (2014). Total synthesis of heronapyrrole C. Organic Letters, 16 (2), 378-381. doi: 10.1021/ol403246j

Total synthesis of heronapyrrole C

2014

Journal Article

Lipopolysaccharide (LPS) stimulation of fungal secondary metabolism

Khalil, Zeinab G., Kalansuriya, Pabasara and Capon, Robert J. (2014). Lipopolysaccharide (LPS) stimulation of fungal secondary metabolism. Mycology, 5 (3), 168-178. doi: 10.1080/21501203.2014.930530

Lipopolysaccharide (LPS) stimulation of fungal secondary metabolism

2013

Journal Article

Sydowiols A-C: Mycobacterium tuberculosis protein tyrosine phosphatase inhibitors from an East China Sea marine-derived fungus, Aspergillus sydowii

Liu, Xinru, Song, Fuhang, Ma, Li, Chen, Caixia, Xiao, Xue, Ren, Biao, Liu, Xueting, Dai, Huanqin, Piggott, Andrew M., Av-Gay, Yossef, Zhang, Lixin and Capon, Robert J. (2013). Sydowiols A-C: Mycobacterium tuberculosis protein tyrosine phosphatase inhibitors from an East China Sea marine-derived fungus, Aspergillus sydowii. Tetrahedron Letters, 54 (45), 6081-6083. doi: 10.1016/j.tetlet.2013.08.137

Sydowiols A-C: Mycobacterium tuberculosis protein tyrosine phosphatase inhibitors from an East China Sea marine-derived fungus, Aspergillus sydowii

2013

Journal Article

Sesterterpene glycinyl-lactams: a new class of glycine receptor modulator from Australian marine sponges of the genus Psammocinia

Balansa, Walter, Islam, Robiul, Fontaine, Frank, Piggott, Andrew M., Zhang, Hua, Xiao, Xue, Webb, Timothy I., Gilbert, Daniel F., Lynch, Joseph W. and Capon, Robert J. (2013). Sesterterpene glycinyl-lactams: a new class of glycine receptor modulator from Australian marine sponges of the genus Psammocinia. Organic and Biomolecular Chemistry, 11 (28), 4695-4701. doi: 10.1039/c3ob40861b

Sesterterpene glycinyl-lactams: a new class of glycine receptor modulator from Australian marine sponges of the genus Psammocinia

2013

Journal Article

Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator

Balansa, Walter, Islam, Robiul, Gilbert, Daniel F., Fontaine, Frank, Xiao, Xue, Zhang, Hua, Piggott, Andrew M., Lynch, Joseph W. and Capon, Robert J. (2013). Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator. Bioorganic and Medicinal Chemistry, 21 (14), 4420-4425. doi: 10.1016/j.bmc.2013.04.061

Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator

2013

Journal Article

Parguerenes: marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells

Huang, Xiao-cong, Sun, Yue-Li, Salim, Angela A., Chen, Zhe-Sheng and Capon, Robert J. (2013). Parguerenes: marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells. Biochemical Pharmacology, 85 (9), 1257-1268. doi: 10.1016/j.bcp.2013.02.005

Parguerenes: marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells

2013

Journal Article

Abyssomicins from the South China Sea deep-sea sediment Verrucosispora sp.: natural thioether michael addition adducts as antitubercular prodrugs

Wang, Qian, Song, Fuhang, Xiao, Xue, Huang, Pei, Li, Li, Monte, Aaron, Abdel-Mageed, Wael M., Wang, Jian, Guo, Hui, He, Wenni, Xie, Feng, Dai, Huanqin, Liu, Miaomiao, Chen, Caixia, Xu, Hao, Liu, Mei, Piggott, Andrew M., Liu, Xueting, Capon, Robert J. and Zhang, Lixin (2013). Abyssomicins from the South China Sea deep-sea sediment Verrucosispora sp.: natural thioether michael addition adducts as antitubercular prodrugs. Angewandte Chemie International Edition, 52 (4), 1231-1234. doi: 10.1002/anie.201208801

Abyssomicins from the South China Sea deep-sea sediment Verrucosispora sp.: natural thioether michael addition adducts as antitubercular prodrugs