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2013

Journal Article

Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator

Balansa, Walter, Islam, Robiul, Gilbert, Daniel F., Fontaine, Frank, Xiao, Xue, Zhang, Hua, Piggott, Andrew M., Lynch, Joseph W. and Capon, Robert J. (2013). Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator. Bioorganic and Medicinal Chemistry, 21 (14), 4420-4425. doi: 10.1016/j.bmc.2013.04.061

Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator

2013

Journal Article

Parguerenes: marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells

Huang, Xiao-cong, Sun, Yue-Li, Salim, Angela A., Chen, Zhe-Sheng and Capon, Robert J. (2013). Parguerenes: marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells. Biochemical Pharmacology, 85 (9), 1257-1268. doi: 10.1016/j.bcp.2013.02.005

Parguerenes: marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells

2013

Journal Article

Abyssomicins from the South China Sea deep-sea sediment Verrucosispora sp.: natural thioether michael addition adducts as antitubercular prodrugs

Wang, Qian, Song, Fuhang, Xiao, Xue, Huang, Pei, Li, Li, Monte, Aaron, Abdel-Mageed, Wael M., Wang, Jian, Guo, Hui, He, Wenni, Xie, Feng, Dai, Huanqin, Liu, Miaomiao, Chen, Caixia, Xu, Hao, Liu, Mei, Piggott, Andrew M., Liu, Xueting, Capon, Robert J. and Zhang, Lixin (2013). Abyssomicins from the South China Sea deep-sea sediment Verrucosispora sp.: natural thioether michael addition adducts as antitubercular prodrugs. Angewandte Chemie International Edition, 52 (4), 1231-1234. doi: 10.1002/anie.201208801

Abyssomicins from the South China Sea deep-sea sediment Verrucosispora sp.: natural thioether michael addition adducts as antitubercular prodrugs

2013

Journal Article

Dual inhibition of DNA polymerase PolC and protein tyrosine phosphatase CpsB uncovers a novel antibiotic target

Standish, Alistair J., Salim, Angela A., Capon, Robert J. and Morona, Renato (2013). Dual inhibition of DNA polymerase PolC and protein tyrosine phosphatase CpsB uncovers a novel antibiotic target. Biochemical and Biophysical Research Communications, 430 (1), 167-172. doi: 10.1016/j.bbrc.2012.11.049

Dual inhibition of DNA polymerase PolC and protein tyrosine phosphatase CpsB uncovers a novel antibiotic target

2013

Journal Article

Nocardiopsins C and D and nocardiopyrone A: new polyketides from an Australian marine-derived Nocardiopsis sp.

Raju, Ritesh, Piggott, Andrew M., Quezada, Michelle and Capon, Robert J. (2013). Nocardiopsins C and D and nocardiopyrone A: new polyketides from an Australian marine-derived Nocardiopsis sp.. Tetrahedron, 69 (2), 692-698. doi: 10.1016/j.tet.2012.10.104

Nocardiopsins C and D and nocardiopyrone A: new polyketides from an Australian marine-derived Nocardiopsis sp.

2012

Journal Article

Staurosporines disrupt phosphatidylserine trafficking and mislocalize ras proteins

Cho, Kwang-jin, Park, Jin-Hee, Piggott, Andrew M., Salim, Angela A., Gorfe, Alemaheyu A., Parton, Robert G., Capon, Robert J., Lacey, Ernest and Hancock, John F. (2012). Staurosporines disrupt phosphatidylserine trafficking and mislocalize ras proteins. Journal of Biological Chemistry, 287 (52), 43573-43584. doi: 10.1074/jbc.M112.424457

Staurosporines disrupt phosphatidylserine trafficking and mislocalize ras proteins

2012

Journal Article

Probing for the pharmacophore of the cytotoxic neoclerodane salvileucalin B

Heinrich, Nora, Banwell, Martin G., Willis, Anthony C., Cade, Ian A., Capon, Robert J. and Huang, Xiao-Cong (2012). Probing for the pharmacophore of the cytotoxic neoclerodane salvileucalin B. Australian Journal of Chemistry, 65 (12), 1679-1686. doi: 10.1071/CH12358

Probing for the pharmacophore of the cytotoxic neoclerodane salvileucalin B

2012

Journal Article

Structural and stereochemical investigations into bromotyrosine-derived metabolites from southern Australian marine sponges, Pseudoceratina spp.

Salim, Angela A., Khalil, Zeinab G. and Capon, Robert J. (2012). Structural and stereochemical investigations into bromotyrosine-derived metabolites from southern Australian marine sponges, Pseudoceratina spp.. Tetrahedron, 68 (47), 9802-9807. doi: 10.1016/j.tet.2012.09.008

Structural and stereochemical investigations into bromotyrosine-derived metabolites from southern Australian marine sponges, Pseudoceratina spp.

2012

Journal Article

Brevianamides with antitubercular potential from a marine-derived isolate of aspergillus versicolor

Song, Fuhang, Liu, Xinru, Guo, Hui, Ren, Biao, Chen, Caixia, Piggott, Andrew M., Yu, Ke, Gao, Hong, Wang, Qian, Liu, Mei, Liu, Xueting, Dai, Huanqin, Zhang, Lixin and Capon, Robert J. (2012). Brevianamides with antitubercular potential from a marine-derived isolate of aspergillus versicolor. Organic Letters, 14 (18), 4770-4773. doi: 10.1021/ol302051x

Brevianamides with antitubercular potential from a marine-derived isolate of aspergillus versicolor

2012

Journal Article

Exploiting intraspecific competitive mechanisms to control invasive cane toads (Rhinella marina)

Crossland, Michael R., Haramura, Takashi, Salim, Angela A., Capon, Robert J. and Shine, Richard (2012). Exploiting intraspecific competitive mechanisms to control invasive cane toads (Rhinella marina). Proceedings of the Royal Society B-Biological Sciences, 279 (1742), 3436-3442. doi: 10.1098/rspb.2012.0821

Exploiting intraspecific competitive mechanisms to control invasive cane toads (Rhinella marina)

2012

Journal Article

Design and application of in vivo FRET biosensors to identify protein prenylation and nanoclustering inhibitors

Kohnke, Monika, Schmitt, Steven, Ariotti, Nicholas, Piggott, Andrew, Parton, Robert G., Lacey, Ernest, Capon, Robert, Alexandrov, Kirill and Abankwa, Daniel (2012). Design and application of in vivo FRET biosensors to identify protein prenylation and nanoclustering inhibitors. Chemistry and Biology, 19 (7), 866-874. doi: 10.1016/j.chembiol.2012.05.019

Design and application of in vivo FRET biosensors to identify protein prenylation and nanoclustering inhibitors

2012

Journal Article

A search for kinase inhibitors and antibacterial agents: bromopyrrolo-2-aminoimidazoles from a deep-water Great Australian Bight sponge, Axinella sp.

Zhang, Hua, Khalil, Zeinab, Conte, Melissa M., Plisson, Fabien and Capon, Robert J. (2012). A search for kinase inhibitors and antibacterial agents: bromopyrrolo-2-aminoimidazoles from a deep-water Great Australian Bight sponge, Axinella sp.. Tetrahedron Letters, 53 (29), 3784-3787. doi: 10.1016/j.tetlet.2012.05.051

A search for kinase inhibitors and antibacterial agents: bromopyrrolo-2-aminoimidazoles from a deep-water Great Australian Bight sponge, Axinella sp.

2012

Journal Article

Microbial biodiscovery: back to the future

Capon, Robert J. (2012). Microbial biodiscovery: back to the future. Current Topics in Medicinal Chemistry, 12 (14), 1471-1478. doi: 10.2174/156802612802652394

Microbial biodiscovery: back to the future

2012

Journal Article

Lamellarins as inhibitors of P-glycoprotein-mediated multidrug resistance in a human colon cancer cell line

Plisson, Fabien, Huang, Xiao-Cong, Zhang, Hua, Khalil, Zeinab and Capon, Robert J. (2012). Lamellarins as inhibitors of P-glycoprotein-mediated multidrug resistance in a human colon cancer cell line. Chemistry - An Asian Journal, 7 (7), 1616-1623. doi: 10.1002/asia.201101049

Lamellarins as inhibitors of P-glycoprotein-mediated multidrug resistance in a human colon cancer cell line

2012

Journal Article

Kinase inhibitor scaffolds against neurodegenerative diseases from a southern Australian Ascidian, Didemnum sp.

Plisson, Fabien, Conte, Melissa, Khalil, Zeinab, Huang, Xiao-Cong, Piggott, Andrew M. and Capon, Robert J. (2012). Kinase inhibitor scaffolds against neurodegenerative diseases from a southern Australian Ascidian, Didemnum sp.. ChemMedChem, 7 (6), 983-990. doi: 10.1002/cmdc.201200169

Kinase inhibitor scaffolds against neurodegenerative diseases from a southern Australian Ascidian, Didemnum sp.

2012

Journal Article

New dictyodendrins as BACE inhibitors from a southern Australian marine sponge, Ianthella sp.

Zhang, Hua, Conte, Melissa M., Khalil, Zeinab, Huang, Xiao-Cong and Capon, Robert J. (2012). New dictyodendrins as BACE inhibitors from a southern Australian marine sponge, Ianthella sp.. Rsc Advances, 2 (10), 4209-4214. doi: 10.1039/c2ra20322g

New dictyodendrins as BACE inhibitors from a southern Australian marine sponge, Ianthella sp.

2012

Journal Article

Chemical inhibition of bacterial protein tyrosine phosphatase suppresses capsule production

Standish, Alistair J., Salim, Angela A., Zhang, Hua, Capon, Robert J. and Morona, Renato (2012). Chemical inhibition of bacterial protein tyrosine phosphatase suppresses capsule production. Plos One, 7 (5) e36312, e36312.1-e36312.8. doi: 10.1371/journal.pone.0036312

Chemical inhibition of bacterial protein tyrosine phosphatase suppresses capsule production

2012

Journal Article

Symphyocladins A-G: bromophenol adducts from a Chinese marine red alga, Symphyocladia latiuscula

Xu, Xiuli, Piggott, Andrew M., Yin, Liyuan, Capon, Robert J. and Song, Fuhang (2012). Symphyocladins A-G: bromophenol adducts from a Chinese marine red alga, Symphyocladia latiuscula. Tetrahedron Letters, 53 (16), 2103-2106. doi: 10.1016/j.tetlet.2012.02.044

Symphyocladins A-G: bromophenol adducts from a Chinese marine red alga, Symphyocladia latiuscula

2012

Journal Article

A search for BACE inhibitors reveals new biosynthetically related pyrrolidones, furanones and pyrroles from a southern Australian marine sponge, Ianthella sp.

Zhang, Hua, Conte, Melissa M., Huang, Xiao-Cong, Khalil, Zeinab and Capon, Robert J. (2012). A search for BACE inhibitors reveals new biosynthetically related pyrrolidones, furanones and pyrroles from a southern Australian marine sponge, Ianthella sp.. Organic and Biomolecular Chemistry, 10 (13), 2656-2663. doi: 10.1039/c2ob06747a

A search for BACE inhibitors reveals new biosynthetically related pyrrolidones, furanones and pyrroles from a southern Australian marine sponge, Ianthella sp.

2012

Journal Article

Heronamycin A: A new benzothiazine ansamycin from an Australian marine-derived Streptomyces sp.

Raju, Ritesh, Piggott, Andrew M., Khalil, Zeinab, Bernhardt, Paul V. and Capon, Robert J. (2012). Heronamycin A: A new benzothiazine ansamycin from an Australian marine-derived Streptomyces sp.. Tetrahedron Letters, 53 (9), 1063-1065. doi: 10.1016/j.tetlet.2011.12.064

Heronamycin A: A new benzothiazine ansamycin from an Australian marine-derived Streptomyces sp.