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2014

Journal Article

Olmsted syndrome with erythromelalgia caused by recessive TRPV3 mutations

Duchatelet, S., Guibbal, L., de Veer, S., Fraitag, S., Nitschké, P., Zarhrate, M., Bodemer, C. and Hovnanian, A. (2014). Olmsted syndrome with erythromelalgia caused by recessive TRPV3 mutations. British Journal of Dermatology, 171 (3), 675-678. doi: 10.1111/bjd.12951

Olmsted syndrome with erythromelalgia caused by recessive TRPV3 mutations

2014

Journal Article

Proteases and proteomics: cutting to the core of human skin pathologies

de Veer, Simon J., Furio, Laetitia, Harris, Jonathan M. and Hovnanian, Alain (2014). Proteases and proteomics: cutting to the core of human skin pathologies. Proteomics - Clinical Applications, 8 (5-6), 389-402. doi: 10.1002/prca.201300081

Proteases and proteomics: cutting to the core of human skin pathologies

2014

Journal Article

Proteases: common culprits in human skin disorders

de Veer, Simon J., Furio, Laetitia, Harris, Jonathan M. and Hovnanian, Alain (2014). Proteases: common culprits in human skin disorders. Trends in Molecular Medicine, 20 (3), 166-178. doi: 10.1016/j.molmed.2013.11.005

Proteases: common culprits in human skin disorders

2014

Journal Article

A new TRPV3 missense mutation in a patient with Olmsted syndrome and erythromelalgia

Duchatelet, Sabine, Pruvost, Solenn, de Veer, Simon, Fraitag, Sylvie, Nitschké, Patrick, Bole-Feysot, Christine, Bodemer, Christine and Hovnanian, Alain (2014). A new TRPV3 missense mutation in a patient with Olmsted syndrome and erythromelalgia. JAMA Dermatology, 150 (3), 303-306. doi: 10.1001/jamadermatol.2013.8709

A new TRPV3 missense mutation in a patient with Olmsted syndrome and erythromelalgia

2014

Journal Article

Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome

Furio, Laetitia, de Veer, Simon, Jaillet, Madeleine, Briot, Anais, Robin, Aurelie, Deraison, Celine and Hovnanian, Alain (2014). Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome. The Journal of Experimental Medicine, 211 (3), 499-513. doi: 10.1084/jem.20131797

Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome

2013

Journal Article

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1

de Veer, Simon J., Ukolova, Svetlana S., Munro, Christopher A., Swedberg, Joakim E., Buckle, Ashley M. and Harris, Jonathan M. (2013). Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1. Biopolymers, 100 (5), 510-518. doi: 10.1002/bip.22231

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1

2012

Conference Publication

Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14

de Veer, Simon J., Swedberg, Joakim E., Parker, Edward A. and Harris, Jonathan M. (2012). Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14. *, *, *. Berlin, Germany: Walter de Gruyter. doi: 10.1515/BC-2011-250

Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14

2012

Journal Article

Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells

Sanchez, Washington Y., de Veer, Simon J., Swedberg, Joakim E., Hong, Eui-Ju, Reid, Janet C., Walsh, Terry P., Hooper, John D., Hammond, Geoffrey L., Clements, Judith A. and Harris, Jonathan M. (2012). Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells. Endocrinology, 153 (7), 3179-3189. doi: 10.1210/en.2012-1011

Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells

2012

Book Chapter

Natural, engineered and synthetic inhibitors of kallikrein-related peptidases

Swedberg, Joakim E., de Veer, Simon J. and Harris, Jonathan M. (2012). Natural, engineered and synthetic inhibitors of kallikrein-related peptidases. Kallikrein-related peptidases: characterization, regulation, and interactions within the protease web. (pp. 141-160) edited by Viktor Magdolen. Berlin, Germany: De Gruyter.

Natural, engineered and synthetic inhibitors of kallikrein-related peptidases

2011

Journal Article

Mastering the canonical loop of serine protease inhibitors: Enhancing potency by optimising the internal hydrogen bond network

Swedberg, Joakim, de Veer, Simon J., Sit, Kei C., Reboul, Cyril F., Buckle, Ashley M. and Harris, Jonathan M. (2011). Mastering the canonical loop of serine protease inhibitors: Enhancing potency by optimising the internal hydrogen bond network. PLoS One, 6 (4) e19302, e19302.1-e19302.11. doi: 10.1371/journal.pone.0019302

Mastering the canonical loop of serine protease inhibitors: Enhancing potency by optimising the internal hydrogen bond network

2010

Conference Publication

Natural and engineered kallikrein inhibitors: An emerging pharmacopeia

Swedberg, Joakim E., de Veer, Simon J. and Harris, Jonathan M. (2010). Natural and engineered kallikrein inhibitors: An emerging pharmacopeia. IKS 2009: 3rd International Symposium on Kallikreins and Kallikrein-Related Peptidases, Munich, Germany, 30 August-2 September 2009. Berlin, Germany: Walter de Gruyter. doi: 10.1515/BC.2010.037

Natural and engineered kallikrein inhibitors: An emerging pharmacopeia

2009

Journal Article

Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4

Swedberg, Joakim E., Nigon, Laura V., Reid, Janet C., de Veer, Simon J., Walpole, Carina M., Stephens, Carson R., Walsh, Terry P., Takayama, Thomas K., Hooper, John D., Clements, Judith A., Buckle, Ashley M. and Harris, Jonathan M. (2009). Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4. Chemistry and Biology, 16 (6), 633-643. doi: 10.1016/j.chembiol.2009.05.008

Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4