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2023 Journal Article 15 years of GWAS discovery: realizing the promiseAbdellaoui, Abdel, Yengo, Loic, Verweij, Karin J. H. and Visscher, Peter M. (2023). 15 years of GWAS discovery: realizing the promise. The American Journal of Human Genetics, 110 (2), 179-194. doi: 10.1016/j.ajhg.2022.12.011 |
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2023 Journal Article Estimation and implications of the genetic architecture of fasting and non-fasting blood glucoseQiao, Zhen, Sidorenko, Julia, Revez, Joana A., Xue, Angli, Lu, Xueling, Pärna, Katri, Snieder, Harold, Visscher, Peter M., Wray, Naomi R., Yengo, Loic and Lifelines Cohort Study (2023). Estimation and implications of the genetic architecture of fasting and non-fasting blood glucose. Nature Communications, 14 (1) 451, 1-11. doi: 10.1038/s41467-023-36013-1 |
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2023 Journal Article Genetic and modifiable risk factors combine multiplicatively in common diseasePang, Shichao, Yengo, Loic, Nelson, Christopher P., Bourier, Felix, Zeng, Lingyao, Li, Ling, Kessler, Thorsten, Erdmann, Jeanette, Mägi, Reedik, Läll, Kristi, Metspalu, Andres, Mueller-Myhsok, Bertram, Samani, Nilesh J., Visscher, Peter M. and Schunkert, Heribert (2023). Genetic and modifiable risk factors combine multiplicatively in common disease. Clinical Research in Cardiology, 112 (2), 247-257. doi: 10.1007/s00392-022-02081-4 |
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2022 Conference Publication Discoveries and lessons from a genome-wide association study of human height in >5 million individualsYengo, L. and on behalf of GIANT Consortium (the height working group) (2022). Discoveries and lessons from a genome-wide association study of human height in >5 million individuals. 12th World Congress on Genetics Applied to Livestock Production (WCGALP), Rotterdam, Netherlands, 3-8 July 2022. Wageningen, Netherlands: Wageningen Academic Publishers. doi: 10.3920/978-90-8686-940-4_3 |
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2022 Journal Article Genomics and phenomics of body mass index reveals a complex disease networkHuang, Jie, Huffman, Jennifer E., Huang, Yunfeng, Do Valle, Ítalo, Assimes, Themistocles L., Raghavan, Sridharan, Voight, Benjamin F., Liu, Chang, Barabási, Albert-László, Huang, Rose D. L., Hui, Qin, Nguyen, Xuan-Mai T., Ho, Yuk-Lam, Djousse, Luc, Lynch, Julie A., Vujkovic, Marijana, Tcheandjieu, Catherine, Tang, Hua, Damrauer, Scott M., Reaven, Peter D., Miller, Donald, Phillips, Lawrence S., Ng, Maggie C. Y., Graff, Mariaelisa, Haiman, Christopher A., Loos, Ruth J. F., North, Kari E., Yengo, Loic, Smith, George Davey ... VA Million Veteran Program (2022). Genomics and phenomics of body mass index reveals a complex disease network. Nature Communications, 13 (1) 7973, 1-10. doi: 10.1038/s41467-022-35553-2 |
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2022 Journal Article The Yearbook: 11 early-career researchers to watchYengo, Loic (2022). The Yearbook: 11 early-career researchers to watch. Nature Medicine, 28 (12), 2441-2443. doi: 10.1038/s41591-022-02133-2 |
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2022 Journal Article Author Correction: Assortative mating biases marker-based heritability estimators (Nature Communications, (2022), 13, 1, (660), 10.1038/s41467-022-28294-9)Border, Richard, O’Rourke, Sean, de Candia, Teresa, Goddard, Michael E., Visscher, Peter M., Yengo, Loic, Jones, Matt and Keller, Matthew C. (2022). Author Correction: Assortative mating biases marker-based heritability estimators (Nature Communications, (2022), 13, 1, (660), 10.1038/s41467-022-28294-9). Nature Communications, 13 (1) 1903, 1903. doi: 10.1038/s41467-022-29652-3 |
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2022 Journal Article Phenotypic and genetic factors associated with donation of DNA and consent to record linkage for prescription history in the Australian Genetics of Depression StudyGomez, Lina, Díaz-Torres, Santiago, Colodro-Conde, Lucía, Garcia-Marin, Luis M., Yap, Chloe X., Byrne, Enda M., Yengo, Loic, Lind, Penelope A., Wray, Naomi R., Medland, Sarah E., Hickie, Ian B., Lupton, Michelle K., Rentería, Miguel E., Martin, Nicholas G. and Campos, Adrian I. (2022). Phenotypic and genetic factors associated with donation of DNA and consent to record linkage for prescription history in the Australian Genetics of Depression Study. European Archives of Psychiatry and Clinical Neuroscience, 273 (6), 1359-1368. doi: 10.1007/s00406-022-01527-0 |
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2022 Journal Article The effect of the scale of grant scoring on ranking accuracyVisscher, Peter M. and Yengo, Loic (2022). The effect of the scale of grant scoring on ranking accuracy. F1000Research, 11 1197, 1-18. doi: 10.12688/f1000research.125400.1 |
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2022 Journal Article A saturated map of common genetic variants associated with human heightYengo, Loïc, Vedantam, Sailaja, Marouli, Eirini, Sidorenko, Julia, Bartell, Eric, Sakaue, Saori, Graff, Marielisa, Eliasen, Anders U., Jiang, Yunxuan, Raghavan, Sridharan, Miao, Jenkai, Arias, Joshua D., Graham, Sarah E., Mukamel, Ronen E., Spracklen, Cassandra N., Yin, Xianyong, Chen, Shyh-Huei, Ferreira, Teresa, Highland, Heather H., Ji, Yingjie, Karaderi, Tugce, Lin, Kuang, Lüll, Kreete, Malden, Deborah E., Medina-Gomez, Carolina, Machado, Moara, Moore, Amy, Rüeger, Sina, Sim, Xueling ... Understanding Society Scientific Group (2022). A saturated map of common genetic variants associated with human height. Nature, 610 (7933), 704-712. doi: 10.1038/s41586-022-05275-y |
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2022 Journal Article Genetic footprints of assortative mating in the Japanese populationYamamoto, Kenichi, Sonehara, Kyuto, Namba, Shinichi, Konuma, Takahiro, Masuko, Hironori, Miyawaki, Satoru, Kamatani, Yoichiro, Hizawa, Nobuyuki, Ozono, Keiichi, Yengo, Loic, Okada, Yukinori and The BioBank Japan Project (2022). Genetic footprints of assortative mating in the Japanese population. Nature Human Behaviour, 7 (1), 1-9. doi: 10.1038/s41562-022-01438-z |
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2022 Journal Article Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translationMahajan, Anubha, Spracklen, Cassandra N., Zhang, Weihua, Ng, Maggie C. Y., Petty, Lauren E., Kitajima, Hidetoshi, Yu, Grace Z., Rüeger, Sina, Speidel, Leo, Kim, Young Jin, Horikoshi, Momoko, Mercader, Josep M., Taliun, Daniel, Moon, Sanghoon, Kwak, Soo-Heon, Robertson, Neil R., Rayner, Nigel W., Loh, Marie, Kim, Bong-Jo, Chiou, Joshua, Miguel-Escalada, Irene, della Briotta Parolo, Pietro, Lin, Kuang, Bragg, Fiona, Preuss, Michael H., Takeuchi, Fumihiko, Nano, Jana, Guo, Xiuqing, Lamri, Amel ... Morris, Andrew P. (2022). Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. Nature Genetics, 54 (5), 560-572. doi: 10.1038/s41588-022-01058-3 |
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2022 Conference Publication The Impact of Socioeconomic Status in the Polygenic Risk of Psychiatric Traits and Disorders: Evidence of Assortative Mating and Participation Bias in UK BiobankMendoza, Brenda Cabrera, Wendt, Frank, Pathak, Gita, Yengo, Loic and Polimanti, Renato (2022). The Impact of Socioeconomic Status in the Polygenic Risk of Psychiatric Traits and Disorders: Evidence of Assortative Mating and Participation Bias in UK Biobank. 77th Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP), New Orleans La, Apr 28-30, 2022. NEW YORK: ELSEVIER SCIENCE INC. |
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2022 Journal Article Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individualsOkbay, Aysu, Wu, Yeda, Wang, Nancy, Jayashankar, Hariharan, Bennett, Michael, Nehzati, Seyed Moeen, Sidorenko, Julia, Kweon, Hyeokmoon, Goldman, Grant, Gjorgjieva, Tamara, Jiang, Yunxuan, Hicks, Barry, Tian, Chao, Hinds, David A., Ahlskog, Rafael, Magnusson, Patrik K E, Oskarsson, Sven, Hayward, Caroline, Campbell, Archie, Porteous, David J., Freese, Jeremy, Herd, Pamela, Watson, Chelsea, Jala, Jonathan, Conley, Dalton, Koellinger, Philipp D., Johannesson, Magnus, Laibson, David, Meyer, Michelle N. ... Social Science Genetic Association Consortium (2022). Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals. Nature Genetics, 54 (4), 437-449. doi: 10.1038/s41588-022-01016-z |
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2022 Journal Article Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence dataWainschtein, Pierrick, Jain, Deepti, Zheng, Zhili, Aslibekyan, Stella, Becker, Diane, Bi, Wenjian, Brody, Jennifer, Carlson, Jenna C., Correa, Adolfo, Du, Margaret Mengmeng, Fernandez-Rhodes, Lindsay, Ferrier, Kendra R., Graff, Misa, Guo, Xiuqing, He, Jiang, Heard-Costa, Nancy L., Highland, Heather M., Hirschhorn, Joel N., Howard-Claudio, Candace M., Isasi, Carmen R., Jackson, Rebecca, Jiang, Jicai, Joehanes, Roby, Justice, Anne E., Kalyani, Rita R., Kardia, Sharon, Lange, Ethan, LeBoff, Meryl, Lee, Seunggeun ... NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium (2022). Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data. Nature Genetics, 54 (3), 263-273. doi: 10.1038/s41588-021-00997-7 |
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2022 Journal Article Constrained human genes under scrutinyYengo, Loic and Colleran, Heidi (2022). Constrained human genes under scrutiny. Nature, 603 (7903), 799-801. doi: 10.1038/d41586-022-00693-4 |
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2022 Journal Article Assortative mating biases marker-based heritability estimatorsBorder, Richard, O’Rourke, Sean, de Candia, Teresa, Goddard, Michael E., Visscher, Peter M., Yengo, Loic, Jones, Matt and Keller, Matthew C. (2022). Assortative mating biases marker-based heritability estimators. Nature Communications, 13 (1) 660. doi: 10.1038/s41467-022-28294-9 |
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2021 Journal Article Mapping the human genetic architecture of COVID-19Niemi, Mari E. K., Karjalainen, Juha, Daly, Mark, Ganna, Andrea, Mehtonen, Juha, Cordioli, Mattia, Kaunisto, Mari, Pigazzini, Sara, Donner, Kati, Kivinen, Katja, Palotie, Aarno, Daly, Mark J., Liao, Rachel G., Kanai, Masahiro, Veerapen, Kumar, Minica, Camelia, Trankiem, Amy, Balaconis, Mary K., Nguyen, Huy, Solomonson, Matthew, Francioli, Laurent, Wang, Qingbo, Green, Robert C., Bryant, Sam, Finucane, Hilary, Martin, Alicia R., Zhou, Wei, Nkambule, Lindokuhle, Karczewski, Konrad J. ... COVID-19 Host Genetics Initiative (2021). Mapping the human genetic architecture of COVID-19. Nature, 600 (7889), 472-477+. doi: 10.1038/s41586-021-03767-x |
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2021 Journal Article Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetesPorcu, Eleonora, Gilardi, Federica, Darrous, Liza, Yengo, Loic, Bararpour, Nasim, Gasser, Marie, Marques-Vidal, Pedro, Froguel, Philippe, Waeber, Gerard, Thomas, Aurelien and Kutalik, Zoltán (2021). Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetes. Scientific Reports, 11 (1) 6197, 6197. doi: 10.1038/s41598-021-85684-7 |
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2021 Journal Article Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (Nature Communications, (2021), 12, 1, (24), 10.1038/s41467-020-19366-9)Lagou, Vasiliki, Mägi, Reedik, Hottenga, Jouke- Jan, Grallert, Harald, Perry, John R. B., Bouatia-Naji, Nabila, Marullo, Letizia, Rybin, Denis, Jansen, Rick, Min, Josine L., Dimas, Antigone S., Ulrich, Anna, Zudina, Liudmila, Gådin, Jesper R., Jiang, Longda, Faggian, Alessia, Bonnefond, Amélie, Fadista, Joao, Stathopoulou, Maria G., Isaacs, Aaron, Willems, Sara M., Navarro, Pau, Tanaka, Toshiko, Jackson, Anne U., Montasser, May E., O’Connell, Jeff R., Bielak, Lawrence F., Webster, Rebecca J., Saxena, Richa ... Prokopenko, Inga (2021). Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (Nature Communications, (2021), 12, 1, (24), 10.1038/s41467-020-19366-9). Nature Communications, 12 (1) 995, 995. doi: 10.1038/s41467-021-21276-3 |
