|
2021 Journal Article Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variabilityLagou, Vasiliki, Mägi, Reedik, Hottenga, Jouke- Jan, Grallert, Harald, Perry, John R. B., Bouatia-Naji, Nabila, Marullo, Letizia, Rybin, Denis, Jansen, Rick, Min, Josine L., Dimas, Antigone S., Ulrich, Anna, Zudina, Liudmila, Gådin, Jesper R., Jiang, Longda, Faggian, Alessia, Bonnefond, Amélie, Fadista, Joao, Stathopoulou, Maria G., Isaacs, Aaron, Willems, Sara M., Navarro, Pau, Tanaka, Toshiko, Jackson, Anne U., Montasser, May E., O’Connell, Jeff R., Bielak, Lawrence F., Webster, Rebecca J., Saxena, Richa ... Prokopenko, Inga (2021). Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nature Communications, 12 (1) 24, 24. doi: 10.1038/s41467-020-19366-9 |
|
2021 Journal Article Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalizationPathak, Gita A., Singh, Kritika, Miller-Fleming, Tyne W., Wendt, Frank R., Ehsan, Nava, Hou, Kangcheng, Johnson, Ruth, Lu, Zeyun, Gopalan, Shyamalika, Yengo, Loic, Mohammadi, Pejman, Pasaniuc, Bogdan, Polimanti, Renato, Davis, Lea K. and Mancuso, Nicholas (2021). Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization. Nature Communications, 12 (1) 4569, 4569. doi: 10.1038/s41467-021-24824-z |
|
2021 Journal Article Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetesPorcu, Eleonora, Gilardi, Federica, Darrous, Liza, Yengo, Loic, Bararpour, Nasim, Gasser, Marie, Marques-Vidal, Pedro, Froguel, Philippe, Waeber, Gerard, Thomas, Aurelien and Kutalik, Zoltán (2021). Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetes. Scientific Reports, 11 (1) 6197, 6197. doi: 10.1038/s41598-021-85684-7 |
|
2021 Conference Publication Polygenic prediction within and between families from a 3-million-person GWAS of educational attainmentOkbay, Aysu, Wu, Yeda, Wang, Nancy, Jayashankar, Hariharan, Bennett, Michael, Nehzati, Seyed Moeen, Sidorenko, Julia, Kweon, Hermon, Goldman, Grant, Gjorgjieva, Tamara, Jiang, Yunxuan, Tian, Chao, Ahlskog, Rafael, Magnusson, Patrik K. E., Oskarsson, Sven, Hayward, Caroline, Campbell, Archie, Porteous, David, Freese, Jeremy, Herd, Pamela, Watson, Chelsea, Jala, Jonathan, Conley, Dalton C., Koellinger, Philipp D., Johannesson, Magnus, Laibson, David I., Meyer, Michelle N., Lee, James J., Kong, Augustine ... Young, Alexander I. (2021). Polygenic prediction within and between families from a 3-million-person GWAS of educational attainment. Behavior Genetics Association 51st Annual Meeting, Online, 2021. New York, NY United States: Springer. doi: 10.1007/s10519-021-10087-3 |
|
2021 Journal Article Polygenic burden could explain high rates of affective disorders in a community with restricted founder populationWang, Xiaotong, Lin, Tian, Yengo, Loic, Sidorenko, Julia, Wray, Naomi R. and Levinson, Douglas F. (2021). Polygenic burden could explain high rates of affective disorders in a community with restricted founder population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 186 (6), 367-375. doi: 10.1002/ajmg.b.32876 |
|
2021 Journal Article Discovery and implications of polygenicity of common diseasesVisscher, Peter M., Yengo, Loic, Cox, Nancy J. and Wray, Naomi R. (2021). Discovery and implications of polygenicity of common diseases. Science, 373 (6562), 1468-1473. doi: 10.1126/science.abi8206 |
|
2021 Journal Article Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibilityvan Blokland, Irene V., Lanting, Pauline, Ori, Anil P.S., Vonk, Judith M., Warmerdam, Robert C.A., Herkert, Johanna C., Boulogne, Floranne, Claringbould, Annique, Lopera-Maya, Esteban A., Bartels, Meike, Hottenga, Jouke-Jan, Ganna, Andrea, Karjalainen, Juha, Hayward, Caroline, Fawns-Ritchie, Chloe, Campbell, Archie, Porteous, David, Cirulli, Elizabeth T., Barrett, Kelly M. Schiabor, Riffle, Stephen, Bolze, Alexandre, White, Simon, Tanudjaja, Francisco, Wang, Xueqing, Ramirez, Jimmy M., Lim, Yan Wei, Lu, James T., Washington, Nicole L., de Geus, Eco J. C. ... Yengo, Loic (2021). Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility. PLoS One, 16 (8) e0255402, 1-18. doi: 10.1371/journal.pone.0255402 |
|
2021 Journal Article Genomic partitioning of inbreeding depression in humansYengo, Loic, Yang, Jian, Keller, Matthew C., Goddard, Michael E., Wray, Naomi R. and Visscher, Peter M. (2021). Genomic partitioning of inbreeding depression in humans. American Journal of Human Genetics, 108 (8), 1488-1501. doi: 10.1016/j.ajhg.2021.06.005 |
|
2021 Journal Article The trans-ancestral genomic architecture of glycemic traitsChen, Ji, Spracklen, Cassandra N., Marenne, Gaëlle, Varshney, Arushi, Corbin, Laura J., Luan, Jian'an, Willems, Sara M., Wu, Ying, Zhang, Xiaoshuai, Horikoshi, Momoko, Boutin, Thibaud S., Mägi, Reedik, Waage, Johannes, Li-Gao, Ruifang, Chan, Kei Hang Katie, Yao, Jie, Anasanti, Mila D., Chu, Audrey Y., Claringbould, Annique, Heikkinen, Jani, Hong, Jaeyoung, Hottenga, Jouke-Jan, Huo, Shaofeng, Kaakinen, Marika A., Louie, Tin, März, Winfried, Moreno-Macias, Hortensia, Ndungu, Anne, Nelson, Sarah C. ... Barroso, Inês (2021). The trans-ancestral genomic architecture of glycemic traits. Nature genetics, 53 (6), 840-860. doi: 10.1038/s41588-021-00852-9 |
|
2021 Journal Article Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals (vol 108, pg 786, 2021)Hivert, Valentin, Sidorenko, Julia, Rohart, Florian, Goddard, Michael E., Yang, Jian, Wray, Naomi R., Yengo, Loic and Visscher, Peter M. (2021). Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals (vol 108, pg 786, 2021). American Journal of Human Genetics, 108 (5), 962-962. doi: 10.1016/j.ajhg.2021.04.012 |
|
2021 Journal Article Erratum: Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: Association with more slow waves and daytime sleepiness (SLEEP DOI: 10.1093/sleep/zsaa137)Muto, Vincenzo, Koshmanova, Ekaterina, Ghaemmaghami, Pouya, Jaspar, Mathieu, Meyer, Christelle, Elansary, Mahmoud, Van Egroo, Maxime, Chylinski, Daphne, Berthomier, Christian, Brandewinder, Marie, Mouraux, Charlotte, Schmidt, Christina, Hammad, Gregory, Coppieters, Wouter, Ahariz, Naima, Degueldre, Christian, Luxen, Andre, Salmon, Eric, Phillips, Christophe, Archer, Simon N, Yengo, Loic, Byrne, Enda, Collette, Fabienne, Georges, Michel, Dijk, Derk-Jan, Maquet, Pierre, Visscher, Peter M and Vandewalle, Gilles (2021). Erratum: Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: Association with more slow waves and daytime sleepiness (SLEEP DOI: 10.1093/sleep/zsaa137). Sleep, 44 (5) zsaa137. doi: 10.1093/sleep/zsab079 |
|
2021 Journal Article Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individualsHivert, Valentin, Sidorenko, Julia, Rohart, Florian, Goddard, Michael E., Yang, Jian, Wray, Naomi R., Yengo, Loic and Visscher, Peter M. (2021). Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals. The American Journal of Human Genetics, 108 (5), 786-798. doi: 10.1016/j.ajhg.2021.02.014 |
|
2021 Journal Article Quantifying genetic heterogeneity between continental populations for human height and body mass indexGuo, Jing, Bakshi, Andrew, Wang, Ying, Jiang, Longda, Yengo, Loic, Goddard, Michael E., Visscher, Peter M. and Yang, Jian (2021). Quantifying genetic heterogeneity between continental populations for human height and body mass index. Scientific Reports, 11 (1) 5240, 1-9. doi: 10.1038/s41598-021-84739-z |
|
2021 Journal Article Widespread signatures of natural selection across human complex traits and functional genomic categoriesZeng, Jian, Xue, Angli, Jiang, Longda, Lloyd-Jones, Luke R., Wu, Yang, Wang, Huanwei, Zheng, Zhili, Yengo, Loic, Kemper, Kathryn E., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2021). Widespread signatures of natural selection across human complex traits and functional genomic categories. Nature Communications, 12 (1) 1164, 1-12. doi: 10.1038/s41467-021-21446-3 |
|
2021 Journal Article Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individualsKemper, Kathryn E., Yengo, Loic, Zheng, Zhili, Abdellaoui, Abdel, Keller, Matthew C., Goddard, Michael E., Wray, Naomi R., Yang, Jian and Visscher, Peter M. (2021). Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals. Nature Communications, 12 (1) 1050, 1050. doi: 10.1038/s41467-021-21283-4 |
|
2021 Journal Article Risk in relatives, heritability, SNP-based heritability and genetic correlations in psychiatric disorders: a reviewBaselmans, Bart M.L., Yengo, Loic, van Rheenen, Wouter and Wray, Naomi R. (2021). Risk in relatives, heritability, SNP-based heritability and genetic correlations in psychiatric disorders: a review. Biological Psychiatry, 89 (1), 11-19. doi: 10.1016/j.biopsych.2020.05.034 |
|
2020 Journal Article Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traitsVogelezang, Suzanne, Bradfield, Jonathan P., Ahluwalia, Tarunveer S., Curtin, John A., Lakka, Timo A., Grarup, Niels, Scholz, Markus, van der Most, Peter J., Monnereau, Claire, Stergiakouli, Evie, Heiskala, Anni, Horikoshi, Momoko, Fedko, Iryna O., Vilor-Tejedor, Natalia, Cousminer, Diana L., Standl, Marie, Wang, Carol A., Viikari, Jorma, Geller, Frank, Íñiguez, Carmen, Pitkänen, Niina, Chesi, Alessandra, Bacelis, Jonas, Yengo, Loic, Torrent, Maties, Ntalla, Ioanna, Helgeland, Øyvind, Selzam, Saskia, Vonk, Judith M. ... Felix, Janine F. (2020). Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits. PLoS Genetics, 16 (10) e1008718, e1008718. doi: 10.1371/journal.pgen.1008718 |
|
2020 Journal Article Pathogenic variants in actionable MODY genes are associated with type 2 diabetesBonnefond, Amélie, Boissel, Mathilde, Bolze, Alexandre, Durand, Emmanuelle, Toussaint, Bénédicte, Vaillant, Emmanuel, Gaget, Stefan, Graeve, Franck De, Dechaume, Aurélie, Allegaert, Frédéric, Guilcher, David Le, Yengo, Loïc, Dhennin, Véronique, Borys, Jean-Michel, Lu, James T., Cirulli, Elizabeth T., Elhanan, Gai, Roussel, Ronan, Balkau, Beverley, Marre, Michel, Franc, Sylvia, Charpentier, Guillaume, Vaxillaire, Martine, Canouil, Mickaël, Washington, Nicole L., Grzymski, Joseph J. and Froguel, Philippe (2020). Pathogenic variants in actionable MODY genes are associated with type 2 diabetes. Nature Metabolism, 2 (10), 1126-1134. doi: 10.1038/s42255-020-00294-3 |
|
2020 Journal Article Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architectureZhang, Qian, Sidorenko, Julia, Couvy-Duchesne, Baptiste, Marioni, Riccardo E., Wright, Margaret J., Goate, Alison M., Marcora, Edoardo, Huang, Kuan-lin, Porter, Tenielle, Laws, Simon M., Australian Imaging Biomarkers and Lifestyle (AIBL) Study, Sachdev, Perminder S., Mather, Karen A., Armstrong, Nicola J., Thalamuthu, Anbupalam, Brodaty, Henry, Yengo, Loic, Yang, Jian, Wray, Naomi R., McRae, Allan F. and Visscher, Peter M. (2020). Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture. Nature Communications, 11 (1) 4799, 1-11. doi: 10.1038/s41467-020-18534-1 |
|
2020 Journal Article Using prior information from humans to prioritize genes and gene-associated variants for complex traits in livestockRaymond, Biaty, Yengo, Loic, Costilla, Roy, Schrooten, Chris, Bouwman, Aniek C., Hayes, Ben J., Veerkamp, Roel F. and Visscher, Peter M. (2020). Using prior information from humans to prioritize genes and gene-associated variants for complex traits in livestock. PLoS Genetics , 16 (9) e1008780, 1-20. doi: 10.1371/journal.pgen.1008780 |
