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2020

Journal Article

Using prior information from humans to prioritize genes and gene-associated variants for complex traits in livestock

Raymond, Biaty, Yengo, Loic, Costilla, Roy, Schrooten, Chris, Bouwman, Aniek C., Hayes, Ben J., Veerkamp, Roel F. and Visscher, Peter M. (2020). Using prior information from humans to prioritize genes and gene-associated variants for complex traits in livestock. PLoS Genetics , 16 (9) e1008780, 1-20. doi: 10.1371/journal.pgen.1008780

Using prior information from humans to prioritize genes and gene-associated variants for complex traits in livestock

2020

Journal Article

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

Wang, Ying, Guo, Jing, Ni, Guiyan, Yang, Jian, Visscher, Peter M. and Yengo, Loic (2020). Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations. Nature Communications, 11 (1) 3865, 3865. doi: 10.1038/s41467-020-17719-y

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

2020

Journal Article

A unified framework for association and prediction from vertex‐wise grey‐matter structure

Couvy‐Duchesne, Baptiste, Strike, Lachlan T., Zhang, Futao, Holtz, Yan, Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Colliot, Olivier, Wright, Margaret J., Wray, Naomi R., Yang, Jian and Visscher, Peter M. (2020). A unified framework for association and prediction from vertex‐wise grey‐matter structure. Human Brain Mapping, 41 (14) hbm.25109, 4062-4076. doi: 10.1002/hbm.25109

A unified framework for association and prediction from vertex‐wise grey‐matter structure

2020

Other Outputs

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

Wang, Ying, Guo, Jing, Ni, Guiyan, Yang, Jian, Visscher, Peter M. and Yengo, Loic (2020). Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations. doi: 10.1101/2020.01.14.905927

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

2019

Journal Article

No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: A reappraisal of Domingue et al (2018)

Yengo, Loic, Sidari, Morgan, Verweij, Karin J. H., Visscher, Peter M., Keller, Matthew C. and Zietsch, Brendan P. (2019). No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: A reappraisal of Domingue et al (2018). Behavior Genetics, 50 (1), 67-71. doi: 10.1007/s10519-019-09979-2

No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: A reappraisal of Domingue et al (2018)

2019

Journal Article

Improved polygenic prediction by Bayesian multiple regression on summary statistics

Lloyd-Jones, Luke R., Zeng, Jian, Sidorenko, Julia, Yengo, Loïc, Moser, Gerhard, Kemper, Kathryn E., Wang, Huanwei, Zheng, Zhili, Magi, Reedik, Esko, Tõnu, Metspalu, Andres, Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2019). Improved polygenic prediction by Bayesian multiple regression on summary statistics. Nature Communications, 10 (1) 5086, 1-10. doi: 10.1038/s41467-019-12653-0

Improved polygenic prediction by Bayesian multiple regression on summary statistics

2019

Journal Article

Genetic correlates of social stratification in Great Britain

Abdellaoui, Abdel, Hugh-Jones, David, Yengo, Loic, Kemper, Kathryn E., Nivard, Michel G., Veul, Laura, Holtz, Yan, Zietsch, Brendan P., Frayling, Timothy M., Wray, Naomi R., Yang, Jian, Verweij, Karin J. H. and Visscher, Peter M. (2019). Genetic correlates of social stratification in Great Britain. Nature Human Behaviour, 3 (12), 1332-1342. doi: 10.1038/s41562-019-0757-5

Genetic correlates of social stratification in Great Britain

2019

Journal Article

Extreme inbreeding in a European ancestry sample from the contemporary UK population

Yengo, Loic, Wray, Naomi R. and Visscher, Peter M. (2019). Extreme inbreeding in a European ancestry sample from the contemporary UK population. Nature Communications, 10 (1) 3719, 3719. doi: 10.1038/s41467-019-11724-6

Extreme inbreeding in a European ancestry sample from the contemporary UK population

2019

Journal Article

Assortative mating in autism spectrum disorder: toward an evidence base from DNA data, but not there yet

Wray, Naomi R. and Yengo, Loic (2019). Assortative mating in autism spectrum disorder: toward an evidence base from DNA data, but not there yet. Biological Psychiatry, 86 (4), 250-252. doi: 10.1016/j.biopsych.2019.06.007

Assortative mating in autism spectrum disorder: toward an evidence base from DNA data, but not there yet

2019

Journal Article

Genome-wide association study of change in fasting glucose over time in 13,807 non-diabetic European ancestry individuals

Liu, Ching-Ti, Merino, Jordi, Rybin, Denis, DiCorpo, Daniel, Benke, Kelly S., Bragg-Gresham, Jennifer L., Canouil, Mickaël, Corre, Tanguy, Grallert, Harald, Isaacs, Aaron, Kutalik, Zoltan, Lahti, Jari, Marullo, Letizia, Marzi, Carola, Rasmussen-Torvik, Laura J., Rocheleau, Ghislain, Rueedi, Rico, Scapoli, Chiara, Verweij, Niek, Vogelzangs, Nicole, Willems, Sara M., Yengo, Loïc, Bakker, Stephan J. L., Beilby, John, Hui, Jennie, Kajantie, Eero, Müller-Nurasyid, Martina, Rathmann, Wolfgang, Balkau, Beverley ... Bouatia-Naji, Nabila (2019). Genome-wide association study of change in fasting glucose over time in 13,807 non-diabetic European ancestry individuals. Scientific Reports, 9 (1) 9439. doi: 10.1038/s41598-019-45823-7

Genome-wide association study of change in fasting glucose over time in 13,807 non-diabetic European ancestry individuals

2019

Other Outputs

No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: a reappraisal of Domingue et al (2018)

Yengo, Loic, Sidari, Morgan, Verweij, Karin J. H., Visscher, Peter M., Keller, Matthew C. and Zietsch, Brendan P. (2019). No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: a reappraisal of Domingue et al (2018). doi: 10.1101/643304

No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: a reappraisal of Domingue et al (2018)

2019

Journal Article

Genome-wide association study of medication-use and associated disease in the UK Biobank

Wu, Yeda, Byrne, Enda M., Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Mallett, Andrew J., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2019). Genome-wide association study of medication-use and associated disease in the UK Biobank. Nature Communications, 10 (1) 1891, 1891. doi: 10.1038/s41467-019-09572-5

Genome-wide association study of medication-use and associated disease in the UK Biobank

2019

Journal Article

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Justice, Anne E., Karaderi, Tugce, Highland, Heather M., Young, Kristin L., Graff, Mariaelisa, Lu, Yingchang, Turcot, Valerie, Auer, Paul L., Fine, Rebecca S., Guo, Xiuqing, Schurmann, Claudia, Lempradl, Adelheid, Marouli, Eirini, Mahajan, Anubha, Winkler, Thomas W., Locke, Adam E., Medina-Gomez, Carolina, Esko, Tonu, Vedantam, Sailaja, Giri, Ayush, Lo, Ken Sin, Alfred, Tamuno, Mudgal, Poorva, Ng, Maggie C. Y., Heard-Costa, Nancy L., Feitosa, Mary F., Manning, Alisa K., Willems, Sara M., Sivapalaratnam, Suthesh ... McCarthy, Mark (2019). Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics, 51 (3), 452-+. doi: 10.1038/s41588-018-0334-2

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

2019

Other Outputs

Improved polygenic prediction by Bayesian multiple regression on summary statistics

Lloyd-Jones, Luke R., Zeng, Jian, Sidorenko, Julia, Yengo, Loïc, Moser, Gerhard, Kemper, Kathryn E., Wang, Huanwei, Zheng, Zhili, Magi, Reedik, Esko, Tonu, Metspalu, Andres, Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2019). Improved polygenic prediction by Bayesian multiple regression on summary statistics. doi: 10.1101/522961

Improved polygenic prediction by Bayesian multiple regression on summary statistics

2019

Conference Publication

Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers

Gratten, Jacob, Yang, Yuanhao, Trzaskowski, Maciej, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Zhang, Futao, Zhu, Zhihong, Mcrae, Allan, Yang, Jian, Wray, Naomi and Visscher, Peter (2019). Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2018.08.167

Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers

2019

Journal Article

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry

Pulit, Sara L., Stoneman, Charli, Morris, Andrew P., Wood, Andrew R., Glastonbury, Craig A., Tyrrell, Jessica, Yengo, Loïc, Ferreira, Teresa, Marouli, Eirini, Ji, Yingjie, Yang, Jian, Jones, Samuel, Beaumont, Robin, Croteau-Chonka, Damien C., Winkler, Thomas W., Consortium, Giant, Hattersley, Andrew T., Loos, Ruth J F, Hirschhorn, Joel N., Visscher, Peter M., Frayling, Timothy M., Yaghootkar, Hanieh and Lindgren, Cecilia M. (2019). Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. Human Molecular Genetics, 28 (1), 166-174. doi: 10.1093/hmg/ddy327

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry

2018

Other Outputs

Genetic analyses of medication-use and implications for precision medicine

Wu, Yeda, Byrne, Enda M., Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Mallett, Andrew J., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2018). Genetic analyses of medication-use and implications for precision medicine. doi: 10.1101/501049

Genetic analyses of medication-use and implications for precision medicine

2018

Journal Article

Assortative mating on complex traits revisited: Double first cousins and the X-chromosome

Yengo, Loic and Visscher, Peter M. (2018). Assortative mating on complex traits revisited: Double first cousins and the X-chromosome. Theoretical Population Biology, 124, 51-60. doi: 10.1016/j.tpb.2018.09.002

Assortative mating on complex traits revisited: Double first cousins and the X-chromosome

2018

Journal Article

Imprint of assortative mating on the human genome

Yengo, Loic, Robinson, Matthew R., Keller, Matthew C., Kemper, Kathryn E., Yang, Yuanhao, Trzaskowski, Maciej, Gratten, Jacob, Turley, Patrick, Cesarini, David, Benjamin, Daniel J., Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2018). Imprint of assortative mating on the human genome. Nature Human Behaviour, 2 (12), 948-954. doi: 10.1038/s41562-018-0476-3

Imprint of assortative mating on the human genome

2018

Journal Article

Erratum: Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness (Nature communications (2018) 9 1 (2537))

Yap, Chloe X., Sidorenko, Julia, Marioni, Riccardo E., Yengo, Loic, Wray, Naomi R. and Visscher, Peter M. (2018). Erratum: Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness (Nature communications (2018) 9 1 (2537)). Nature communications, 9 (1) 4953, 4953. doi: 10.1038/s41467-018-07400-w

Erratum: Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness (Nature communications (2018) 9 1 (2537))