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2015 Journal Article Obesity and the outcome of young breast cancer patients in the UK: The POSH studyCopson, E. R., Cutress, R. I., Maishman, T., Eccles, B. K., Gerty, S., Stanton, L., Altman, D. G., Durcan, L., Wong, C., Simmonds, P. D., Jones, L., Eccles, D. M., POSH Study Steering Group and Lakhani, S. (2015). Obesity and the outcome of young breast cancer patients in the UK: The POSH study. Annals of Oncology, 26 (1), 101-112. doi: 10.1093/annonc/mdu509 |
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2015 Journal Article ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotypeJunankar, Simon, Baker, Laura A., Roden, Daniel L., Nair, Radhika, Elsworth, Ben, Gallego-Ortega, David, Lacaze, Paul, Cazet, Aurelie, Nikolic, Iva, Teo, Wee Siang, Yang, Jessica, McFarland, Andrea, Harvey, Kate, Naylor, Matthew J., Lakhani, Sunil R., Simpson, Peter T., Raghavendra, Ashwini, Saunus, Jodi, Madore, Jason, Kaplan, Warren, Ormandy, Christopher, Millar, Ewan K. A., O'Toole, Sandra, Yun, Kyuson and Swarbrick, Alexander (2015). ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype. Nature Communications, 6 (1) 6548, 6548.1-6548.12. doi: 10.1038/ncomms7548 |
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2014 Journal Article Erratum: Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancerAl-Ejeh, F, Simpson, P T, Saunus, J M, Klein, K, Kalimutho, M, Shi, W, Miranda, M, Kutasovic, J, Raghavendra, A, Madore, J, Reid, L, Krause, L, Chenevix-Trench, G, Lakhani, S R and Khanna, K K (2014). Erratum: Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer. Oncogenesis, 3 (10) e124, e124-e124. doi: 10.1038/oncsis.2014.41 |
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2014 Journal Article Is the one-step nucleic acid amplification assay better for intra-operative assessment of breast sentinel nodes?Bettington, Mark, Lakhani, Sunil R. and Ung, Owen A. (2014). Is the one-step nucleic acid amplification assay better for intra-operative assessment of breast sentinel nodes?. ANZ Journal of Surgery, 84 (10), 725-729. doi: 10.1111/ans.12497 |
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2014 Journal Article Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomesTubio, Jose M. C., Li, Yilong, Ju, Young S., Martincorena, Inigo, Cooke, Susanna L., Tojo, Marta, Gundem, Gunes, Pipinikas, Christodoulos P., Zamora, Jorge, Raine, Keiran, Menzies, Andrew, Roman-Garcia, Pablo, Fullam, Anthony, Gerstung, Moritz, Shlien, Adam, Tarpey, Patrick S., Papaemmanuil, Elli, Knappskog, Stian, Van Loo, Peter, Ramakrishna, Manasa, Davies, Helen R., Marshall, John, Wedge, David C., Teague, Jon W., Butler, Adam P., Nik-Zainal, Serena, Alexandrov, Ludmil, Behjati, Sam, Yates, Lucy R. ... Simpson, Peter (2014). Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes. Science, 345 (6196) 1251343, 1251343.1-1251343.12. doi: 10.1126/science.1251343 |
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2014 Journal Article COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatmentGenerali, D., Buffa, F. M., Deb, S., Cummings, M., Reid, L. E., Taylor, M., Andreis, D., Allevi, G., Ferrero, G., Byrne, D., Martinotti, M., Bottini, A., Harris, A. L., Lakhani, S. R. and Fox, S. B. (2014). COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment. British Journal of Cancer, 111 (1), 46-54. doi: 10.1038/bjc.2014.236 |
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2014 Journal Article Molecular classification of breast cancerVuong, Darina, Simpson, Peter T., Green, Benjamin, Cummings, Margaret C. and Lakhani, Sunil R. (2014). Molecular classification of breast cancer. Virchows Archiv, 465 (1), 1-14. doi: 10.1007/s00428-014-1593-7 |
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2014 Journal Article Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancerAl-Ejeh, F., Simpson, P. T., Sanus, J. M., Klein, K., Kalimutho, M., Shi, W., Miranda, M., Kutasovic, J., Raghavendra, A., Madore, J., Reid, L., Krause, L., Chenevix-Trench, G., Lakhani, S. R. and Khanna, K. K. (2014). Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer. Oncogenesis, 3 (4) e100, 1-12. doi: 10.1038/oncsis.2014.14 |
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2014 Journal Article Processed pseudogenes acquired somatically during cancer developmentCooke, Susanna L., Shlien, Adam, Marshall, John, Pipinikas, Christodoulos P., Martincorena, Inigo, Tubio, Jose M. C., Li, Yilong, Menzies, Andrew, Mudie, Laura, Ramakrishna, Manasa, Yates, Lucy, Davies, Helen, Bolli, Niccolo, Bignell, Graham R., Tarpey, Patrick S., Behjati, Sam, Nik-Zainal, Serena, Papaemmanuil, Elli, Teixeira, Vitor H., Raine, Keiran, O'Meara, Sarah, Dodoran, Maryam S., Teague, Jon W., Butler, Adam P., Iacobuzio-Donahue, Christine, Santarius, Thomas, Grundy, Richard G., Malkin, David, Greaves, Mel ... Lakhani, Sunil R. (2014). Processed pseudogenes acquired somatically during cancer development. Nature Communications, 5 (1) 3644, 3644.1-3644.9. doi: 10.1038/ncomms4644 |
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2014 Journal Article Multifactorial likelihood assessment of BRCA1 and BRCA2 missense variants confirms that BRCA1:c.122A>G(p.His41Arg) is a pathogenic mutationWhiley, Phillip J., Parsons, Michael T., Leary, Jennifer, Tucker, Kathy, Warwick, Linda, Dopita, Belinda, Thorne, Heather, Lakhani, Sunil R., Goldgar, David E., Brown, Melissa A. and Spurdle, Amanda B. (2014). Multifactorial likelihood assessment of BRCA1 and BRCA2 missense variants confirms that BRCA1:c.122A>G(p.His41Arg) is a pathogenic mutation. PloS One, 9 (1) e86836, 1-10. doi: 10.1371/journal.pone.0086836 |
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2014 Journal Article Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancerAl-Ejeh, Fares, Miranda, Mariska, Shi,Wei, Simpson, Peter T., Song, Sarah, Vargas, Ana Cristina, Saunus, Jodi M., Smart, Chanel E., Mariasegaram, Mythily, Wiegmans, Adrian P., Chenevix-Trench, Georgia, Lakhani, Sunil R. and Khanna, Kum Kum (2014). Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer. Oncotarget, 5 (10), 3145-3158. doi: 10.18632/oncotarget.1865 |
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2014 Journal Article Rad51 supports triple negative breast cancer metastasisWiegmans, Adrian P., Al-Ejeh, Fares, Chee, Nicole, Yap, Pei-Yi, Gorski, Julia J., Da Silva, Leonard, Bolderson, Emma, Chenevix-Trench, Georgia, Anderson, Robin, Simpson, Peter T., Lakhani, Sunil R. and Khanna, Kum Kum (2014). Rad51 supports triple negative breast cancer metastasis. Oncotarget, 5 (10), 3261-3272. doi: 10.18632/oncotarget.1923 |
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2014 Journal Article Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian womenTilch, E., Seidens, T., Cocciardi, S., Reid, L. E., Byrne, D., Simpson, P. T., Vargas, A. C., Cummings, M. C., Fox, S. B., Lakhani, S. R. and Chenevix Trench, G. (2014). Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian women. Breast Cancer Research and Treatment, 143 (2), 385-392. doi: 10.1007/s10549-013-2798-1 |
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2014 Journal Article Metastatic progression of breast cancer: Insights from 50 years of autopsiesCummings, Margaret C., Simpson, Peter T., Reid, Lynne E., Jayanthan, Janani, Skerman, Joanna, Song, Sarah, McCart Reed, Amy E., Kutasovic, Jamie R., Morey, Adrienne L., Marquart, Louise, O'Rourke, Peter and Lakhani, Sunil R. (2014). Metastatic progression of breast cancer: Insights from 50 years of autopsies. Journal of Pathology, 232 (1), 23-31. doi: 10.1002/path.4288 |
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2014 Journal Article Ethnicity and outcome of young breast cancer patients in the United Kingdom: the POSH studyCopson, E., Maishman, T., Gerty, S., Eccles, B., Stanton, L., Cutress, R. I., Altman, D. G., Durcan, L., Simmonds, P., Jones, L., Tapper W., Eccles, D., POSH study steering group and Lakhani, Sunil (2014). Ethnicity and outcome of young breast cancer patients in the United Kingdom: the POSH study. British Journal of Cancer, 110 (1), 230-241. doi: 10.1038/bjc.2013.650 |
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2013 Journal Article miR-139-5p is a regulator of metastatic pathways in breast cancerKrishnan, Keerthana, Steptoe, Anita, Martin, Hilary, Pattabiraman, Diwakar R., Nones, Katia, Waddell, Nicola, Mariasegaram, Mythily, Simpson, Peter T., Lakhani, Sunil R., Vlassov, Alexander, Grimmond, Sean M. and Cloonan, Nicole (2013). miR-139-5p is a regulator of metastatic pathways in breast cancer. RNA, 19 (12), 1767-1780. doi: 10.1261/rna.042143.113 |
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2013 Journal Article c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancerNair, R., Roden, D. L., Teo, W. S., McFarland, A., Junankar, S., Ye, S., Nguyen, A., Yang, J., Nikolic, I., Hui, M., Morey, A., Shah, J., Pfefferle, A. D., Usary, J., Selinger, C., Baker, L. A., Armstrong, N., Cowley, M. J., Naylor, M. J., Ormandy, C. J., Lakhani, S. R., Herschkowitz, J. I., Perou, C. M., Kaplan, W., O'Toole, S. A. and Swarbrick, A. (2013). c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer. Oncogene, 33 (30), 3992-4002. doi: 10.1038/onc.2013.368 |
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2013 Journal Article Signatures of mutational processes in human cancerAlexandrov, Ludmil B., Nik-Zainal, Serena, Wedge, David C., Aparicio, Samuel A. J. R., Behjati, Sam, Biankin, Andrew V., Bignell, Graham R., Bolli, Niccolo, Borg, Ake, Borresen-Dale, Anne-Lise, Boyault, Sandrine, Burkhardt, Birgit, Butler, Adam P., Caldas, Carlos, Davies, Helen R., Desmedt, Christine, Eils, Roland, Eyfjord, Jorunn Erla, Foekens, John A., Greaves, Mel, Hosoda, Fumie, Hutter, Barbara, Ilicic, Tomislav, Imbeaud, Sandrine, Imielinsk, Marcin, Jaeger, Natalie, Jones, David T. W., Jones, David, Knappskog, Stian ... Stratton, Michael R. (2013). Signatures of mutational processes in human cancer. Nature, 500 (7463), 415-421. doi: 10.1038/nature12477 |
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2013 Journal Article Intraoperative imprint cytology for breast cancer sentinel nodes: is it worth it?Richards, Angela D. M., Lakhani, Sunil R., James, Daniel T. and Ung, Owen A. (2013). Intraoperative imprint cytology for breast cancer sentinel nodes: is it worth it?. ANZ Journal of Surgery, 83 (7-8), 539-544. doi: 10.1111/j.1445-2197.2012.06293.x |
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2013 Journal Article Mammographic and ultrasound features of invasive lobular carcinoma of the breastPorter, Alan J., Evans, Elizabeth B., Foxcroft, Loani M., Simpson, Peter T. and Lakhani, Sunil R. (2013). Mammographic and ultrasound features of invasive lobular carcinoma of the breast. Journal of Medical Imaging and Radiation Oncology, 58 (1), 1-10. doi: 10.1111/1754-9485.12080 |
