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2016

Journal Article

The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin

Peters, Amelia A., Milevskiy, Michael J. G., Lee, WeiC., Curry, Merril C., Smart, Chanel E., Saunus, Jodi M., Reid, Lynne, da Silva, Leonard, Marcial, Daneth L., Dray, Eloise, Brown, Melissa A., Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2016). The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin. Scientific Reports, 6 (1) 25505, 25505. doi: 10.1038/srep25505

The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin

2016

Journal Article

The topography of mutational processes in breast cancer genomes

Morganella, Sandro, Alexandrov, Ludmil B., Glodzik, Dominik, Zou, Xueqing, Davies, Helen, Staaf, Johan, Sieuwerts, Anieta M., Brinkman, Arie B., Martin, Sancha, Ramakrishna, Manasa, Butler, Adam, Kim, Hyung-Yong, Borg, Ake, Sotiriou, Christos, Futreal, P. Andrew, Campbell, Peter J., Span, Paul N., Van Laere, Steven, Lakhani, Sunil R., Eyfjord, Jorunn E., Thompson, Alastair M., Stunnenberg, Hendrik G., van de Vijver, Marc J., Martens, John W. M., Borresen-Dale, Anne-Lise, Richardson, Andrea L., Kong, Gu, Thomas, Gilles, Sale, Julian ... Nik-Zainal, Serena (2016). The topography of mutational processes in breast cancer genomes. Nature Communications, 7 (11383) 11383, 1-11. doi: 10.1038/ncomms11383

The topography of mutational processes in breast cancer genomes

2016

Journal Article

Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer

Field, Sarah, Uyttenhove, Catherine, Stroobant, Vincent, Cheou, Paméla, Coutelier, Jean-Paul, Simpson, Peter T., Cummings, Margaret C., Saunus, Jodi M., Reid, Lynne E., Kutasovic, Jamie R., McNicol, Anne Marie, Kim, Ba Reun, Kim, Jae Ho, Lakhani, Sunil R., Neville, A. Munro, Van Snick, Jacques and Jat, Parmjit S. (2016). Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer. International Journal of Cancer, 138 (8), 1959-1970. doi: 10.1002/ijc.29946

Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer

2016

Journal Article

High content screening application for cell-type specific behaviour in heterogeneous primary breast epithelial subpopulations

Johnston, Rebecca L., Wockner, Leesa, McCart Reed, Amy E., Wiegmans, Adrian, Chenevix-Trench, Georgia, Khanna, Kum Kum, Lakhani, Sunil R. and Smart, Chanel E. (2016). High content screening application for cell-type specific behaviour in heterogeneous primary breast epithelial subpopulations. Breast Cancer Research, 18 (18) 18, 1-18. doi: 10.1186/s13058-016-0681-9

High content screening application for cell-type specific behaviour in heterogeneous primary breast epithelial subpopulations

2016

Book Chapter

Future role of molecular profiling in small breast samples and personalized medicine

Sim, Sarah Yen Mi, Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2016). Future role of molecular profiling in small breast samples and personalized medicine. A comprehensive guide to core needle biopsies of the breast. (pp. 803-817) edited by Sandra J. Shin. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-26291-8

Future role of molecular profiling in small breast samples and personalized medicine

2016

Book Chapter

Forgotten resources - the autopsy

Smith, Deborah, Reed, Amy McCart and Lakhani, Sunil R. (2016). Forgotten resources - the autopsy. Molecular pathology in cancer research. (pp. 335-348) edited by Sunil R. Lakhani and Stephen B. Fox. New York, NY, U.S.A.: Springer . doi: 10.1007/978-1-4939-6643-1_15

Forgotten resources - the autopsy

2016

Journal Article

Phyllodes tumours of the breast: A consensus review

Tan, Benjamin Y., Acs, Geza, Apple, Sophia K., Badve, Sunil, Bleiweiss, Ira J., Brogi, Edi, Calvo, Jose P., Dabbs, David J., Ellis, Ian O., Eusebi, Vincenzo, Farshid, Gelareh, Fox, Stephen B., Ichihara, Shu, Lakhani, Sunil R., Rakha, Emad A., Reis-Filho, Jorge S., Richardson, Andrea L., Sahin, Aysegul, Schmitt, Fernando C., Schnitt, Stuart J., Siziopikou, Kalliopi P., Soares, Fernando A., Tse, Gary M., Vincent-Salomon, Anne and Puay Hoon Tan (2016). Phyllodes tumours of the breast: A consensus review. Histopathology, 68 (1), 5-21. doi: 10.1111/his.12876

Phyllodes tumours of the breast: A consensus review

2016

Conference Publication

Investigating the Her2-3 dimer as a theranostic target in brain metastases

Saunus, Jodi M., Kalita-de Croft, Priyakshi, Lee, F. T., Al-Ejeh, Fares, Lim, Malcolm, Ensbey, Kathleen, Niland, Colleen, Jeffree, Rosalind L., Thomas, Paul, Day, Bryan W., Rose, Stephen, Scott, Andrew M. and Lakhani, Sunil R. (2016). Investigating the Her2-3 dimer as a theranostic target in brain metastases. COSA's 43 and ANZBCTG's 38 Annual Scientific Meetings. Partners for Progress in Breast Cancer Research and Care, Gold Coast, QLD Australia, 15-17 November 2016. Chichester, West Sussex United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/ajco.12646

Investigating the Her2-3 dimer as a theranostic target in brain metastases

2016

Conference Publication

An integrative analysis of invasive lobular breast cancer

Lal, Samir, McCart Reed, Amy E, Nones, Katia, Wockner Leesa, Song, Sarah, Waddell, Nic, Lakhani, Sunil and Simpson, Peter t (2016). An integrative analysis of invasive lobular breast cancer. Lorne Cancer Conference, Lorne VIC, Australia, February 11-13th 2016.

An integrative analysis of invasive lobular breast cancer

2016

Book

Basic pathology: an introduction to the mechanisms of disease

Lakhani, Sunil R., Dilly, Susan A., Finlayson, Caroline J. and Gandhi, Mitesh (2016). Basic pathology: an introduction to the mechanisms of disease. 5th ed. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315381688

Basic pathology: an introduction to the mechanisms of disease

2016

Book Chapter

Future role of molecular profiling in small breast samples and personalised medicine

Sim, Sarah Yen Mi, Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2016). Future role of molecular profiling in small breast samples and personalised medicine. A comprehensive guide to core needle biopsies of the breast. (pp. 803-817) edited by Sandra J. Shin. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-26291-8_23

Future role of molecular profiling in small breast samples and personalised medicine

2016

Book Chapter

Introduction: Setting the scene, morphology to molecular

Fox, Stephen B. and Lakhani, Sunil R. (2016). Introduction: Setting the scene, morphology to molecular. Molecular pathology in cancer research. (pp. v-vi) edited by Sunil R. Lakhani and Stephen B. Fox. New York, United States: Springer.

Introduction: Setting the scene, morphology to molecular

2016

Journal Article

An epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomas

McCart Reed, Amy E., Kutasovic, Jamie R., Vargas, Ana Cristina, Jayanthan, Janani, Al-Murrani, Amel, Reid, Lynne E., Chambers, Rachael, Da Silva, Leonard, Melville, Lewis, Evans, Elizabeth, Porter, Alan, Papadimos, David, Thompson, Erik W., Lakhani, Sunil R. and Simpson, Peter T. (2016). An epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomas. Journal of Pathology, 238 (4), 489-494. doi: 10.1002/path.4668

An epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomas

2016

Journal Article

The cancer genetics and pathology of male breast cancer

Deb, Siddhartha, Lakhani, Sunil R., Ottini, Laura and Fox, Stephen B. (2016). The cancer genetics and pathology of male breast cancer. Histopathology, 68 (1), 110-118. doi: 10.1111/his.12862

The cancer genetics and pathology of male breast cancer

2016

Conference Publication

Next Generation Sequencing On Endobronchial Ultrasound Transbronchial Needle Aspirate Lymph Node Specimens in Lung Cancer Shows a High Incidence of Mutations and Consistency with Single Gene Testing

Fielding, D., Bashirzadeh, F., Singh, M., Nandakumar, L., Reed, Mccart A., Black, D., Dalley, A., Pearson, J., Nones, K., Waddell, N., Simpson, P. and Lakhani, S. (2016). Next Generation Sequencing On Endobronchial Ultrasound Transbronchial Needle Aspirate Lymph Node Specimens in Lung Cancer Shows a High Incidence of Mutations and Consistency with Single Gene Testing. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA, Australia, 1-6 April 2016. Wiley. doi: 10.1111/resp.12754_12

Next Generation Sequencing On Endobronchial Ultrasound Transbronchial Needle Aspirate Lymph Node Specimens in Lung Cancer Shows a High Incidence of Mutations and Consistency with Single Gene Testing

2016

Journal Article

RAD51B in familial breast cancer

Pelttari, Liisa M., Khan, Sofia, Vuorela, Mikko, Kiiski, Johanna I., Vilske, Sara, Nevanlinna, Viivi, Ranta, Salla, Schleutker, Johanna, Winqvist, Robert, Kallioniemi, Anne, Dörk, Thilo, Bogdanova, Natalia V., Figueroa, Jonine, Pharoah, Paul D. P., Schmidt, Marjanka K., Dunning, Alison M., García-Closas, Montserrat, Bolla, Manjeet K., Dennis, Joe, Michailidou, Kyriaki, Wang, Qin, Hopper, John L., Southey, Melissa C., Rosenberg, Efraim H., Fasching, Peter A., Beckmann, Matthias W., Peto, Julian, Dos-Santos-silva, Isabel, Sawyer, Elinor J. ... Zeps, N. (2016). RAD51B in familial breast cancer. PLoS One, 11 (5) e0153788, e0153788. doi: 10.1371/journal.pone.0153788

RAD51B in familial breast cancer

2016

Conference Publication

The development of personalized diagnostic tests and therapeutic strategies in breast cancer

Kutasovic, Jamie R., Rozali, Esdy, Miranda, Mariska, Lakhani, Sunil R. and Al-Ejeh, Fares (2016). The development of personalized diagnostic tests and therapeutic strategies in breast cancer. COSA's 43rd and ANZBCTG's 38th Annual Scientific Meetings. Partners for Progress in Breast Cancer Research and Care, Gold Coast, QLD Australia, 15-17 November 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

The development of personalized diagnostic tests and therapeutic strategies in breast cancer

2016

Book

Molecular pathology in cancer research

Sunil R. Lakhani and Stephen B. Fox eds. (2016). Molecular pathology in cancer research. New York, United States: Springer. doi: 10.1007/978-1-4939-6643-1

Molecular pathology in cancer research

2015

Journal Article

TGFβ isoforms and receptors mRNA expression in breast tumours: Prognostic value and clinical implications

Chen, Chenfeng, Zhao, Kong-Nan, Masci, Paul P., Lakhani, Sunil R., Antonsson, Annika, Simpson, Peter T. and Vitetta, Luis (2015). TGFβ isoforms and receptors mRNA expression in breast tumours: Prognostic value and clinical implications. BMC Cancer, 15 (1010) 1010, 1010. doi: 10.1186/s12885-015-1993-3

TGFβ isoforms and receptors mRNA expression in breast tumours: Prognostic value and clinical implications

2015

Journal Article

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

Zhang, Lin, Zhang, Siyuan, Yao, Jun, Lowery, Frank J., Zhang, Qingling, Huang, Wen-Chien, Li, Ping, Li, Min, Wang, Xiao, Zhang, Chenyu, Wang, Hai, Ellis, Kenneth, Cheerathodi, Mujeeburahiman, McCarty, Joseph H., Palmieri, Diane, Saunus, Jodi, Lakhani, Sunil, Huang, Suyun, Sahin, Aysegul A., Aldape, Kenneth D., Steeg, Patricia S. and Yu, Dihua (2015). Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth. Nature, 527 (7576), 100-104. doi: 10.1038/nature15376

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth