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2016 Book Chapter Future role of molecular profiling in small breast samples and personalized medicineSim, Sarah Yen Mi, Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2016). Future role of molecular profiling in small breast samples and personalized medicine. A comprehensive guide to core needle biopsies of the breast. (pp. 803-817) edited by Sandra J. Shin. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-26291-8 |
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2016 Book Chapter Forgotten resources - the autopsySmith, Deborah, Reed, Amy McCart and Lakhani, Sunil R. (2016). Forgotten resources - the autopsy. Molecular pathology in cancer research. (pp. 335-348) edited by Sunil R. Lakhani and Stephen B. Fox. New York, NY, U.S.A.: Springer . doi: 10.1007/978-1-4939-6643-1_15 |
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2015 Journal Article TGFβ isoforms and receptors mRNA expression in breast tumours: Prognostic value and clinical implicationsChen, Chenfeng, Zhao, Kong-Nan, Masci, Paul P., Lakhani, Sunil R., Antonsson, Annika, Simpson, Peter T. and Vitetta, Luis (2015). TGFβ isoforms and receptors mRNA expression in breast tumours: Prognostic value and clinical implications. BMC Cancer, 15 (1010) 1010, 1010. doi: 10.1186/s12885-015-1993-3 |
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2015 Journal Article Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowthZhang, Lin, Zhang, Siyuan, Yao, Jun, Lowery, Frank J., Zhang, Qingling, Huang, Wen-Chien, Li, Ping, Li, Min, Wang, Xiao, Zhang, Chenyu, Wang, Hai, Ellis, Kenneth, Cheerathodi, Mujeeburahiman, McCarty, Joseph H., Palmieri, Diane, Saunus, Jodi, Lakhani, Sunil, Huang, Suyun, Sahin, Aysegul A., Aldape, Kenneth D., Steeg, Patricia S. and Yu, Dihua (2015). Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth. Nature, 527 (7576), 100-104. doi: 10.1038/nature15376 |
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2015 Journal Article Integrated genomic and transcriptomic analysis of human brain metastases identifies recurrently altered pathways of potential clinical significanceSaunus, Jodi M., Quinn, MIchael C. J., Patch, Ann-Marie, Pearson, John V., Bailey, Peter J., Nones, Katia, McCart Reed, Amy E., Miller, David, Peter J. Wilson, Al-Ejeh, Fares, Mariasegaram, Mythily, Lau, Queenie, Withers, Teresa, Jeffree, Rosalind L., Reid, Lynne E., Da Silva, Leonard, Matsika, Admire, Niland, Colleen M., Cummings, Margaret C., Bruxner, Timothy J. C., Christ, Angelika N., Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wani, Shivangi, Anderson, Matthew J., Fink, J. Lynn ... Lakhani, Sunil R. (2015). Integrated genomic and transcriptomic analysis of human brain metastases identifies recurrently altered pathways of potential clinical significance. Journal of Pathology, 237 (3), 363-378. doi: 10.1002/path.4583 |
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2015 Journal Article Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using GefitinibBessette, Darrell C., Tilch, Erik, Seidens, Tatjana, Quinn, Michael C. J., Wiegmans, Adrian P., Shi, Wei, Cocciardi, Sibylle, McCart-Reed, Amy, Saunus, Jodi M., Simpson, Peter T., Grimmond, Sean M., Lakhani, Sunil R., Khanna, Kum Kum, Waddell, Nic, Al-Ejeh, Fares and Chevenvix-Trench, Georgia (2015). Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib. PLoS One, 10 (5) e0125232, e0125232-e0125232. doi: 10.1371/journal.pone.0125232 |
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2015 Journal Article Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cellsJu, Young Seok, Tubio, Jose M.C, Mifsud, William, Fu, Beiyuan, Davies, Helen R, Ramakrishna, Manasa, Li, Yilong, Yates, Lucy, Gundem, Gunes, Tarpey, Patrick S, Behjati, Sam, Papaemmanuil, Elli, Martin, Sancha, Fullam, Anthony, Gerstung, Moritz, Nangalia, Jyoti, Green, Anthony R, Caldas, Carlos, Borg, Ake, Tutt, Andrew, Michael Lee, Ming Ta, Van'T Veer, Laura J, Tan, Benita K.T, Aparicio, Samuel, Span, Paul N, Martens, John W.M, Knappskog, Stian, Vincent-Salomon, Ann, Borresen-Dale, Anne-Lise ... Simpson, Peter (2015). Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells. Genome Research, 25 (6), 814-824. doi: 10.1101/gr.190470.115 |
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2015 Journal Article Papillary and neuroendocrine breast lesions: the WHO stanceTan, Puay Hoon, Schnitt, Stuart J., van de Vijver, Marc J., Ellis, Ian O. and Lakhani, Sunil R. (2015). Papillary and neuroendocrine breast lesions: the WHO stance. Histopathology, 66 (6), 761-770. doi: 10.1111/his.12463 |
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2015 Journal Article An evaluation of the prognostic model PREDICT using the POSH cohort of women aged ≤40 years at breast cancer diagnosisMaishman, T., Copson, E., Stanton, L., Gerty, S., Dicks, E., Durcan, L., Wishart, G. C., Pharoah, P., POSH Steering Group, Lakhani, Sunil and Eccles, D. (2015). An evaluation of the prognostic model PREDICT using the POSH cohort of women aged ≤40 years at breast cancer diagnosis. British Journal of Cancer, 112 (6), 983-991. doi: 10.1038/bjc.2015.57 |
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2015 Journal Article Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell linesMomeny, Majid, Saunus, Jodi M., Marturana, Flavia, McCart Reed, Amy E., Black, Debra, Sala, Gianluca, Iacobelli, Stefano, Holland, Jane D., Yu, Dihua, Da Silva, Leonard, Simpson, Peter T., Khanna, Kum Kum, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2015). Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines. Oncotarget, 6 (6), 3932-3946. doi: 10.18632/oncotarget.2846 |
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2015 Journal Article Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omicsMcCart Reed, Amy E., Kutasovic, Jamie R., Lakhani, Sunil R. and Simpson, Peter T. (2015). Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics. Breast Cancer Research, 17 (12) 12, 1-11. doi: 10.1186/s13058-015-0519-x |
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2015 Conference Publication Flipping pathology and its impact on learning in second year medical students at University of Queensland, School of Medicine, AustraliaKoteeswaran, Raja, Deborah Smith, Ekta Bhutada, Simpson, Peter T., Emma Bartle, Julie Elizabeth Ayre, Galea, Melanie, Joanne Lester, Bowker, Shari and Lakhani, Sunil (2015). Flipping pathology and its impact on learning in second year medical students at University of Queensland, School of Medicine, Australia. The 2015 AAMC Medical Education Meeting, Baltimore, Maryland, USA, 10-12 November 2015. |
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2015 Conference Publication Breast cancer metastasis to gynaecological organs: impacting young women diagnosed with a luminal tumour subtypeKutasovic, Jamie, Reed, Amy McCart, Sim, Sarah, Cummings, Margaret, Lakhani, Sunil and Simpson, Peter (2015). Breast cancer metastasis to gynaecological organs: impacting young women diagnosed with a luminal tumour subtype. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3 |
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2015 Conference Publication The role of epithelial to mesenchymal plasticity in driving the invasive capacity of 'lobular-like' tumour cell differentiation in breast cancerReed, McCart A. E., Kutasovic, J. R., Vargas, A. C., Da Silva, L., Jayanthan, J., Al-Murrani, A., Reid, L. E., Evans, E., Porter, A., Lakhani, S. R. and Simpson, P. T. (2015). The role of epithelial to mesenchymal plasticity in driving the invasive capacity of 'lobular-like' tumour cell differentiation in breast cancer. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3 |
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2015 Journal Article ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotypeJunankar, Simon, Baker, Laura A., Roden, Daniel L., Nair, Radhika, Elsworth, Ben, Gallego-Ortega, David, Lacaze, Paul, Cazet, Aurelie, Nikolic, Iva, Teo, Wee Siang, Yang, Jessica, McFarland, Andrea, Harvey, Kate, Naylor, Matthew J., Lakhani, Sunil R., Simpson, Peter T., Raghavendra, Ashwini, Saunus, Jodi, Madore, Jason, Kaplan, Warren, Ormandy, Christopher, Millar, Ewan K. A., O'Toole, Sandra, Yun, Kyuson and Swarbrick, Alexander (2015). ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype. Nature Communications, 6 (1) 6548, 6548.1-6548.12. doi: 10.1038/ncomms7548 |
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2015 Conference Publication The inhibitor of differentiation proteins mediate tumour-initiating properties and metastasis in breast cancerNair, Radhika, Teo, Wee Siang, Ye, Sunny, McFarland, Andrea, Harvey, Kate, Roden, Daniel, Junankar, Simon, Baker, Laura, Yang, Jessica, Fluke, Nicola, Millar, Ewan, Mellick, Albert, Naylor, Matthew, Ormandy, Christopher, Lakhani, Sunil, O'Toole, Sandra and Swarbrick, Alexander (2015). The inhibitor of differentiation proteins mediate tumour-initiating properties and metastasis in breast cancer. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3 |
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2015 Conference Publication Exploring the HER3 tyrosine kinase as a therapeutic target for treatment of brain metastasesSaunus, Jodi M., Momeny, Majid, Da Silva, Leonard, Reid, Lynne, Holland, Jane D., Birchmeier, Walter, Jat, Parmjit, Brandner, Sebastian, Al-Ejeh, Fares, Khanna, Kum Kum, Chenevix-Trench, Georgia, Simpson, Peter T. and Lakhani, Sunil R. (2015). Exploring the HER3 tyrosine kinase as a therapeutic target for treatment of brain metastases. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, 28 June - 01 July 2014. Dordrecht, Netherlands: Springer. doi: 10.1007/s10585-015-9708-3 |
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2015 Conference Publication Erk5 as a therapeutic target in triple negative breast cancer (TNBC)Miranda, Mariska Sauzine, Al Ejeh, Fares, Shi, Wei, Simpson, Peter, Lakhani, Sunil and Khanna, Kum Kum (2015). Erk5 as a therapeutic target in triple negative breast cancer (TNBC). 37th Annual CTRC-AACR San Antonio Breast Cancer Symposium, San Antonio, TX, United States, 9-13 December 2014. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS14-P6-03-11 |
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2015 Journal Article Obesity and the outcome of young breast cancer patients in the UK: The POSH studyCopson, E. R., Cutress, R. I., Maishman, T., Eccles, B. K., Gerty, S., Stanton, L., Altman, D. G., Durcan, L., Wong, C., Simmonds, P. D., Jones, L., Eccles, D. M., POSH Study Steering Group and Lakhani, S. (2015). Obesity and the outcome of young breast cancer patients in the UK: The POSH study. Annals of Oncology, 26 (1), 101-112. doi: 10.1093/annonc/mdu509 |
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2015 Conference Publication Genomic and transcriptomic landscapes of human brain metastasesSaunus, J. M., Quinn, M. C. J., Patch, A. M., Pearson, J. V., Bailey, P. J., Cloonan, N., Nones, K., Miller, D., Mariasegaram, M., Lau, Q., Jeffree, L., Khanna, K. K., Chenevix-Trench, G., Grimmond, S. M., Simpson, P. T., Waddell, N. and Lakhani, S. R. (2015). Genomic and transcriptomic landscapes of human brain metastases. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3 |
