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2014 Journal Article Molecular classification of breast cancerVuong, Darina, Simpson, Peter T., Green, Benjamin, Cummings, Margaret C. and Lakhani, Sunil R. (2014). Molecular classification of breast cancer. Virchows Archiv, 465 (1), 1-14. doi: 10.1007/s00428-014-1593-7 |
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2014 Journal Article Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancerAl-Ejeh, F., Simpson, P. T., Sanus, J. M., Klein, K., Kalimutho, M., Shi, W., Miranda, M., Kutasovic, J., Raghavendra, A., Madore, J., Reid, L., Krause, L., Chenevix-Trench, G., Lakhani, S. R. and Khanna, K. K. (2014). Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer. Oncogenesis, 3 (4) e100, 1-12. doi: 10.1038/oncsis.2014.14 |
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2014 Journal Article Processed pseudogenes acquired somatically during cancer developmentCooke, Susanna L., Shlien, Adam, Marshall, John, Pipinikas, Christodoulos P., Martincorena, Inigo, Tubio, Jose M. C., Li, Yilong, Menzies, Andrew, Mudie, Laura, Ramakrishna, Manasa, Yates, Lucy, Davies, Helen, Bolli, Niccolo, Bignell, Graham R., Tarpey, Patrick S., Behjati, Sam, Nik-Zainal, Serena, Papaemmanuil, Elli, Teixeira, Vitor H., Raine, Keiran, O'Meara, Sarah, Dodoran, Maryam S., Teague, Jon W., Butler, Adam P., Iacobuzio-Donahue, Christine, Santarius, Thomas, Grundy, Richard G., Malkin, David, Greaves, Mel ... Lakhani, Sunil R. (2014). Processed pseudogenes acquired somatically during cancer development. Nature Communications, 5 (1) 3644, 3644.1-3644.9. doi: 10.1038/ncomms4644 |
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2014 Journal Article Multifactorial likelihood assessment of BRCA1 and BRCA2 missense variants confirms that BRCA1:c.122A>G(p.His41Arg) is a pathogenic mutationWhiley, Phillip J., Parsons, Michael T., Leary, Jennifer, Tucker, Kathy, Warwick, Linda, Dopita, Belinda, Thorne, Heather, Lakhani, Sunil R., Goldgar, David E., Brown, Melissa A. and Spurdle, Amanda B. (2014). Multifactorial likelihood assessment of BRCA1 and BRCA2 missense variants confirms that BRCA1:c.122A>G(p.His41Arg) is a pathogenic mutation. PloS One, 9 (1) e86836, 1-10. doi: 10.1371/journal.pone.0086836 |
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2014 Journal Article Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancerAl-Ejeh, Fares, Miranda, Mariska, Shi,Wei, Simpson, Peter T., Song, Sarah, Vargas, Ana Cristina, Saunus, Jodi M., Smart, Chanel E., Mariasegaram, Mythily, Wiegmans, Adrian P., Chenevix-Trench, Georgia, Lakhani, Sunil R. and Khanna, Kum Kum (2014). Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer. Oncotarget, 5 (10), 3145-3158. doi: 10.18632/oncotarget.1865 |
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2014 Journal Article Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian womenTilch, E., Seidens, T., Cocciardi, S., Reid, L. E., Byrne, D., Simpson, P. T., Vargas, A. C., Cummings, M. C., Fox, S. B., Lakhani, S. R. and Chenevix Trench, G. (2014). Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian women. Breast Cancer Research and Treatment, 143 (2), 385-392. doi: 10.1007/s10549-013-2798-1 |
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2014 Conference Publication PMCA2 in human breast tissue with lactational change and in human breast cancer cellsPeters, Amelia A., Lee, Wei C., Dray, Eloise , Smart, Chanel E., Reid, Lynne , da Silva, Leonard , Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2014). PMCA2 in human breast tissue with lactational change and in human breast cancer cells. 13th International Meeting of the European Calcium Society, Aix-en-Provence, France, 13-17 September 2014. |
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2014 Journal Article Metastatic progression of breast cancer: Insights from 50 years of autopsiesCummings, Margaret C., Simpson, Peter T., Reid, Lynne E., Jayanthan, Janani, Skerman, Joanna, Song, Sarah, McCart Reed, Amy E., Kutasovic, Jamie R., Morey, Adrienne L., Marquart, Louise, O'Rourke, Peter and Lakhani, Sunil R. (2014). Metastatic progression of breast cancer: Insights from 50 years of autopsies. Journal of Pathology, 232 (1), 23-31. doi: 10.1002/path.4288 |
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2014 Journal Article Rad51 supports triple negative breast cancer metastasisWiegmans, Adrian P., Al-Ejeh, Fares, Chee, Nicole, Yap, Pei-Yi, Gorski, Julia J., Da Silva, Leonard, Bolderson, Emma, Chenevix-Trench, Georgia, Anderson, Robin, Simpson, Peter T., Lakhani, Sunil R. and Khanna, Kum Kum (2014). Rad51 supports triple negative breast cancer metastasis. Oncotarget, 5 (10), 3261-3272. doi: 10.18632/oncotarget.1923 |
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2014 Conference Publication Update on WHO breast classification: 2 years onLakhani, Sunil R. (2014). Update on WHO breast classification: 2 years on. IAP 2014: 30th Congress of the International Academy of Pathology 2014, Bangkok, Thailand, 5-10 October, 2014. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1097/01.PAT.0000454053.47289.16 |
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2014 Conference Publication Calcium efflux pump, PMCA2, in human breast tissue with lactational change and as a therapeutic target in breast cancerPeters, Amelia A., Lee, Wei C., Dray, Eloise, Smart, Chanel E., Reid, Lynne , da Silva, Leonard , Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2014). Calcium efflux pump, PMCA2, in human breast tissue with lactational change and as a therapeutic target in breast cancer. 2nd Annual Congress of The European Society for Translational Medicine Medicine, Vienna, Austria, 22-25 September 2014. |
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2014 Conference Publication Id4 Controls Mammary Stem Cells and Marks Breast Cancers with a Stem Cell Like PhenotypeJunankar, Simon, Baker, Laura, Roden, Daniel, Nair, Radhika, Elsworth, Ben, Lakhani, Sunil, Simpson, Peter, Ormandy C, Chris, O'Toole, Sandra and Swarbrick, Alexander (2014). Id4 Controls Mammary Stem Cells and Marks Breast Cancers with a Stem Cell Like Phenotype. Sydney Cancer Conference 2014, University of Sydney, NSW Australia, 26 November 2014. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/ajco.12282 |
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2014 Journal Article Ethnicity and outcome of young breast cancer patients in the United Kingdom: the POSH studyCopson, E., Maishman, T., Gerty, S., Eccles, B., Stanton, L., Cutress, R. I., Altman, D. G., Durcan, L., Simmonds, P., Jones, L., Tapper W., Eccles, D., POSH study steering group and Lakhani, Sunil (2014). Ethnicity and outcome of young breast cancer patients in the United Kingdom: the POSH study. British Journal of Cancer, 110 (1), 230-241. doi: 10.1038/bjc.2013.650 |
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2014 Book Chapter Breast CancerSchnitt, Stuart J. and Lakhani, Sunil S. (2014). Breast Cancer. World Cancer Report. (pp. 362-373) edited by Bernard W. Stewart and Christopher P. Wild. Lyon, France: IARC. |
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2013 Journal Article miR-139-5p is a regulator of metastatic pathways in breast cancerKrishnan, Keerthana, Steptoe, Anita, Martin, Hilary, Pattabiraman, Diwakar R., Nones, Katia, Waddell, Nicola, Mariasegaram, Mythily, Simpson, Peter T., Lakhani, Sunil R., Vlassov, Alexander, Grimmond, Sean M. and Cloonan, Nicole (2013). miR-139-5p is a regulator of metastatic pathways in breast cancer. RNA, 19 (12), 1767-1780. doi: 10.1261/rna.042143.113 |
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2013 Journal Article c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancerNair, R., Roden, D. L., Teo, W. S., McFarland, A., Junankar, S., Ye, S., Nguyen, A., Yang, J., Nikolic, I., Hui, M., Morey, A., Shah, J., Pfefferle, A. D., Usary, J., Selinger, C., Baker, L. A., Armstrong, N., Cowley, M. J., Naylor, M. J., Ormandy, C. J., Lakhani, S. R., Herschkowitz, J. I., Perou, C. M., Kaplan, W., O'Toole, S. A. and Swarbrick, A. (2013). c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer. Oncogene, 33 (30), 3992-4002. doi: 10.1038/onc.2013.368 |
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2013 Journal Article Signatures of mutational processes in human cancerAlexandrov, Ludmil B., Nik-Zainal, Serena, Wedge, David C., Aparicio, Samuel A. J. R., Behjati, Sam, Biankin, Andrew V., Bignell, Graham R., Bolli, Niccolo, Borg, Ake, Borresen-Dale, Anne-Lise, Boyault, Sandrine, Burkhardt, Birgit, Butler, Adam P., Caldas, Carlos, Davies, Helen R., Desmedt, Christine, Eils, Roland, Eyfjord, Jorunn Erla, Foekens, John A., Greaves, Mel, Hosoda, Fumie, Hutter, Barbara, Ilicic, Tomislav, Imbeaud, Sandrine, Imielinsk, Marcin, Jaeger, Natalie, Jones, David T. W., Jones, David, Knappskog, Stian ... Stratton, Michael R. (2013). Signatures of mutational processes in human cancer. Nature, 500 (7463), 415-421. doi: 10.1038/nature12477 |
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2013 Journal Article Intraoperative imprint cytology for breast cancer sentinel nodes: is it worth it?Richards, Angela D. M., Lakhani, Sunil R., James, Daniel T. and Ung, Owen A. (2013). Intraoperative imprint cytology for breast cancer sentinel nodes: is it worth it?. ANZ Journal of Surgery, 83 (7-8), 539-544. doi: 10.1111/j.1445-2197.2012.06293.x |
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2013 Journal Article Mammographic and ultrasound features of invasive lobular carcinoma of the breastPorter, Alan J., Evans, Elizabeth B., Foxcroft, Loani M., Simpson, Peter T. and Lakhani, Sunil R. (2013). Mammographic and ultrasound features of invasive lobular carcinoma of the breast. Journal of Medical Imaging and Radiation Oncology, 58 (1), 1-10. doi: 10.1111/1754-9485.12080 |
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2013 Journal Article In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneitySmart, Chanel E., Morrison, Brian J., Saunus, Jodi M., Vargas, Ana Cristina, Keith, Patricia, Reid, Lynne, Wockner, Leesa, Amiri, Marjan Askarian, Sarkar, Debina, Simpson, Peter T., Clarke, Catherine, Schmidt, Chris W., Reynolds, Brent A., Lakhani, Sunil R. and Lopez, J. Alejandro (2013). In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneity. PloS One, 8 (6) e64388, e64388. doi: 10.1371/journal.pone.0064388 |