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2011

Conference Publication

The transient receptor potential V6 (TRPV6) calcium channel in breast cancer cell lines and clinical breast cancer tissues

Peters, Amelia, Simpson, Peter T., Bassett, Johnathon, Lakhani, Sunil, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2011). The transient receptor potential V6 (TRPV6) calcium channel in breast cancer cell lines and clinical breast cancer tissues. American Association for Cancer Research 102nd Annual Meeting, Orlando, United States, 2 - 6 April 2011. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2011-2954

The transient receptor potential V6 (TRPV6) calcium channel in breast cancer cell lines and clinical breast cancer tissues

2011

Conference Publication

Calcium Channel Transient Receptor Potential V6 (TRPV6) in Breast Cancer Cell Lines and in Breast Tumours

Peters Amelia A., Simpson, Peter T., Bassett ,John J., Da Silva Leo, Reid, Lynne, Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2011). Calcium Channel Transient Receptor Potential V6 (TRPV6) in Breast Cancer Cell Lines and in Breast Tumours. 5th PacRim Breast and Prostate Cancer Meeting, Kingscliffe, NSW, Australia, 3-7 May 2011.

Calcium Channel Transient Receptor Potential V6 (TRPV6) in Breast Cancer Cell Lines and in Breast Tumours

2011

Book Chapter

Genetic alterations in normal and malignant breast tissue

Smart, Chanel, Simpson, Peter T., Vargas, Ana Cristina and Lakhani, Sunil R. (2011). Genetic alterations in normal and malignant breast tissue. Breast cancer, a lobar disease. (pp. 53-66) edited by Tot, Tibor. London, United Kingdom: Springer. doi: 10.1007/978-1-84996-314-5_4

Genetic alterations in normal and malignant breast tissue

2011

Conference Publication

The role of Type XI Collagen in Breast Cancer Progression

Vargas, Ana Cristina, Simpson, Peter T., McCart Reed, Amy E., Smart, Chanel, Waddell, Nic, Lane, Annette and Lakhani, Sunil (2011). The role of Type XI Collagen in Breast Cancer Progression. LICR Translational Oncology Conference, Melbourne, Australia, 24-26 October 2011.

The role of Type XI Collagen in Breast Cancer Progression

2011

Conference Publication

Expression of the calcium pump PMCA2 in lactating breast and breast cancer

Lee, W. C., Reid, L., Smart, Chanel, Simpson, P. T., Da Silva, L., Peters, Amelia, Lakhani, Sunil, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2011). Expression of the calcium pump PMCA2 in lactating breast and breast cancer. ComBio 2011, Cairns, Australia, 25-29 September 2011.

Expression of the calcium pump PMCA2 in lactating breast and breast cancer

2011

Journal Article

Molecular aspects of breast cancer metastasis to the brain

Saunus, Jodi M., Momeny, Majid, Simpson, Peter T., Da Silva, Leonard and Lakhani, Sunil R. (2011). Molecular aspects of breast cancer metastasis to the brain. Genetics Research International, 2011, 219189-1-219189-9. doi: 10.4061/2011/219189

Molecular aspects of breast cancer metastasis to the brain

2011

Conference Publication

The Transient Receptor Potential V6 (TRPV6) channel in clinical breast cancers and breast cancer cell lines

Peters, Amelia A., Simpson, Peter T., Bassett, John J., Da Silva, Leo, Reid, Lynne, Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory, R. (2011). The Transient Receptor Potential V6 (TRPV6) channel in clinical breast cancers and breast cancer cell lines. 17th International Symposium on Calcium-Binding Proteins and Calcium Function in Health and Disease (CaBP17), Beijing, China, 16-21 July 2011.

The Transient Receptor Potential V6 (TRPV6) channel in clinical breast cancers and breast cancer cell lines

2010

Journal Article

The contribution of breast cancer pathology to statistical models to predict mutation risk in BRCA carriers

Vargas, AC, Da Silva, L and Lakhani, SR (2010). The contribution of breast cancer pathology to statistical models to predict mutation risk in BRCA carriers. Familial Cancer, 9 (4), 545-553. doi: 10.1007/s10689-010-9362-5

The contribution of breast cancer pathology to statistical models to predict mutation risk in BRCA carriers

2010

Journal Article

Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes

Al-Ejeh, F., Kumar, R., Wiegmans, A., Lakhani, S.R., Brown, M.P. and Khanna, K.K. (2010). Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes. Oncogene, 29 (46), 6085-6098. doi: 10.1038/onc.2010.407

Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes

2010

Journal Article

DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast

Huang, Katie T., Dobrovic, Alexander, Yan, Max, Karim, Rooshdiya Z., Lee, C. Soon, Lakhani, Sunil R. and Fox, Stephen B. (2010). DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast. Breast Cancer Research and Treatment, 124 (2), 555-565. doi: 10.1007/s10549-010-0970-4

DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast

2010

Journal Article

Common genetic variants and modification of penetrance of BRCA2-associated breast cancer

Mia M. Gaudet, Tomas Kirchhoff, Todd Green, Joseph Vijai, Joshua M. Korn, Candace Guiducci, Ayellet V. Segre, Kate McGee, Lesley McGuffog, Christiana Kartsonaki, Jonathan Morrison, Sue Healey, Olga M. Sinilnikova, Dominique Stoppa-Lyonnet, Sylvie Mazoyer, Marion Gauthier-Villars, Hagay Sobol, Michel Longy, Marc Frenay, GEMO Study Collaborators, Frans B. L. Hogervorst, Matti a. Rookus, J. Margriet Collee, Nicoline Hoogerbrugge, Kees E. P. van Roozendaal, HEBON Study Collaborators, Marion Piedmonte, Wendy Rubinstein, Stacy Nerenstone ... Lakhani, Sunil (2010). Common genetic variants and modification of penetrance of BRCA2-associated breast cancer. PLoS Genetics, 6 (10), e1001183-1-e1001183-12. doi: 10.1371/journal.pgen.1001183

Common genetic variants and modification of penetrance of BRCA2-associated breast cancer

2010

Journal Article

Subtypes of familial breast tumours revealed by expression and copy number profiling

Waddell, N, Arnold, J, Cocciardi, S, da Silva, L, Marsh, A, Riley, J, Johnstone, CN, Orloff, M, Assie, G, Eng, C, Reid, L, Keith, P, Yan, M, Fox, S, Devilee, P, Godwin, AK, Hogervorst, FBL, Couch, F, Grimmond, S, Flanagan, JM, Khanna, K, Simpson, PT, Lakhani, SR, Chenevix-Trench, G and kConFab Investigators (2010). Subtypes of familial breast tumours revealed by expression and copy number profiling. Breast Cancer Research And Treatment, 123 (3), 661-677. doi: 10.1007/s10549-009-0653-1

Subtypes of familial breast tumours revealed by expression and copy number profiling

2010

Journal Article

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

Antoniou, Antonis C., Wang, Xianshu, Fredericksen, Zachary S., McGuffog, Lesley, Tarrell, Robert, Sinilnikova, Olga M., Healey, Sue, Morrison, Jonathan, Kartsonaki,Christiana, Lesnick, Timothy, Ghoussaini, Maya, Barrowdale, Daniel, Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, Eccles, Diana, Evans, D. Gareth, Eeles, Ros, Izatt, Louise, Chu, Carol, Douglas, Fiona, Paterson, Joan, Stoppa-Lyonnet, Dominique, Houdayer, Claude, Mazoyer, Sylvie, Giraud, Sophie, Lasset, Christine, Remenieras, Audrey ... Lakhani, Sunil (2010). A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population. Nature Genetics, 42 (10), 885-892. doi: 10.1038/ng.669

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

2010

Journal Article

Gene expression profiling of formalin-fixed, paraffin-embedded familial breast tumours using the whole genome-DASL assay

Waddell, Nic, Cocciardi, Sibylle, Johnson, Julie, Healey, Sue, Marsh, Anna, Riley, Joan, da Silva, Leonard, Vargas, Ana Cristina, Reid, Lynne, Simpson, Peter T., Lakhani, Sunil R. and Chenevix-Trench, Georgia (2010). Gene expression profiling of formalin-fixed, paraffin-embedded familial breast tumours using the whole genome-DASL assay. Journal of Pathology, 221 (4), 452-461. doi: 10.1002/path.2728

Gene expression profiling of formalin-fixed, paraffin-embedded familial breast tumours using the whole genome-DASL assay

2010

Journal Article

Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers

Wang, Xianshu, Pankratz, V. Shane, Fredericksen, Zachary, Tarrell, Robert, Karaus, Mary, McGuffog, Lesley, Pharaoh, Paul D.P., Ponder, Bruce A.J., Dunning, Alison M., Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, EMBRACE, Sinilnikova, Olga M., Stoppa-Lyonnet, Dominique, Mazoyer, Sylvie, Houdayer, Claude, GEMO, Hogervorst, Frans B.L., Hooning, Maartje J., Ligtenberg, Marjolijn J., HEBON, Spurdle, Amanda, Chenevix-Trench, Georgia, kConFab, Schmutzler, Rita K., Wappenschmidt, Barbara, Engel, Christoph ... Lakhani, Sunil (2010). Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers. Human Molecular Genetics, 19 (14), 2886-2897. doi: 10.1093/hmg/ddq174

Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers

2010

Journal Article

Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines

Alexopoulou, Annika N., Leao, Maria, Caballero, Otavia L., Da Silva, Leonard, Reid, Lynne, Lakhani, Sunil R., Simpson, Andrew J., Marshall, John F., Neville, A. Munro and Jat, Parmjit S. (2010). Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines. Breast Cancer Research, 12 (4) R51, R51-1-R51-17. doi: 10.1186/bcr2610

Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines

2010

Journal Article

Detection of Splicing Aberrations Caused by BRCA1 and BRCA2 Sequence Variants Encoding Missense Substitutions: Implications for Prediction of Pathogenicity

Walker, Logan C., Whiley, Phillip J., Couch, Fergus J., Farrugia, Daniel J., Healey, Sue, Eccles, Diana M., Lin, Feng, Butler, Samantha A., Goff, Sheila A., Thompson, Bryony A., Lakhani, Sunil R., Da Silva, Leonard M., Tavtigian, Sean V., Goldgar, David E., Brown, Melissa A. and Spurdle, Amanda B. (2010). Detection of Splicing Aberrations Caused by BRCA1 and BRCA2 Sequence Variants Encoding Missense Substitutions: Implications for Prediction of Pathogenicity. Human Mutation, 31 (6), E1484-E1505. doi: 10.1002/humu.21267

Detection of Splicing Aberrations Caused by BRCA1 and BRCA2 Sequence Variants Encoding Missense Substitutions: Implications for Prediction of Pathogenicity

2010

Journal Article

Incorporating tumour pathology information into breast cancer risk prediction algorithms

Mavaddat, Nasim, Rebbeck, Timothy R., Lakhani, Sunil R., Easton, Douglas F. and Antoniou, Antonis C. (2010). Incorporating tumour pathology information into breast cancer risk prediction algorithms. Breast Cancer Research, 12 (3) R28, R28 - 1-R28 - 12. doi: 10.1186/bcr2576

Incorporating tumour pathology information into breast cancer risk prediction algorithms

2010

Journal Article

Pathology of hereditary breast cancer

Da Silva, Leonard and Lakhani, Sunil R. (2010). Pathology of hereditary breast cancer. Modern Pathology, 23 (S2), S46-S51. doi: 10.1038/modpathol.2010.37

Pathology of hereditary breast cancer

2010

Conference Publication

Lynch syndrome-associated breast cancers: clinicopathological characteristics of a case series from the Colon CFR

Rosty, Christophe, Walsh, Michael, Cummings, Margaret, Buchanan, Daniel, Arnold, Sven, McKeone, Diane, Walters, Rhiannon, Hopper, John, Jenkins, Mark, Spurdle, Amanda, McGuckin, Michael, Lakhani, Sunil and Young, Joanne (2010). Lynch syndrome-associated breast cancers: clinicopathological characteristics of a case series from the Colon CFR. AACR 101st Annual Meeting 2010, Washington, DC, United States, 17-21 April 2010. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM10-32

Lynch syndrome-associated breast cancers: clinicopathological characteristics of a case series from the Colon CFR