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2010

Journal Article

DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status

Flanagan, James M., Cocciardi, Sibylle, Waddell, Nic, Johnstone, Cameron N., Marsh, Anna, Henderson, Stephen, Simpson, Peter, da Silva, Leonard, kConFab Investigators, Khanna, Kumkum, Lakhani, Sunil, Boshoff, Chris, Chenevix-Trench, Georgia, Brown, Melissa, Cummings, Margaret and Edwards, Stacey (2010). DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. American Journal of Human Genetics, 86 (3), 420-433. doi: 10.1016/j.ajhg.2010.02.008

DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status

2010

Journal Article

Bayes analysis provides evidence of pathogenicity for the BRCA1 c.135-1G>T (IVS3-1) and BRCA2 c.7977-1G>C (IVS17-1) variants displaying in vitro splicing results of equivocal clinical significance.

Spurdle, Amanda B., Lakhani, Sunil R., Da Silva, Leonard M., Balleine, Rosemary L., kConFab Investigators and Goldgar, David E. (2010). Bayes analysis provides evidence of pathogenicity for the BRCA1 c.135-1G>T (IVS3-1) and BRCA2 c.7977-1G>C (IVS17-1) variants displaying in vitro splicing results of equivocal clinical significance.. Human Mutation, 31 (2), E1141-E1145. doi: 10.1002/humu.21181

Bayes analysis provides evidence of pathogenicity for the BRCA1 c.135-1G>T (IVS3-1) and BRCA2 c.7977-1G>C (IVS17-1) variants displaying in vitro splicing results of equivocal clinical significance.

2010

Journal Article

Breast pathology: Beyond morphology

Simpson, Peter T., Reis-Filho, Jorge S. and Lakhani, Sunil R. (2010). Breast pathology: Beyond morphology. Seminars in Diagnostic Pathology, 27 (1), 91-96. doi: 10.1053/j.semdp.2009.12.001

Breast pathology: Beyond morphology

2010

Journal Article

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

Da Silva, Leonard, Simpson, Peter T., Smart, Chanek E., Cocciardi, Sibylle, Waddell, Nic, Lane, Annette, Morrison, Brian J., Vargas, Ana Cristina, Healey, Sue, Beesley, Jonathan, Pakkiri, Pria, Parry, Suzanne, Kurniawan, Nyoman, Reid, Lynne, Keith, Patricia, Faria, Paulo, Pereira, Emilio, Skalova, Alena, Bilous, Michael, Balleine, Rosemary L., Do, Hongdo, Dobrovic, Alexander, Fox, Stephen, Franco, Marcello, Reynolds, Brent, Khanna, Kum Kum, Cummings, Margaret, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2010). HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer. Breast Cancer Research, 12 (4) R46, R46-1-R46-11. doi: 10.1186/bcr2603

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

2010

Conference Publication

Role of breast screening for characterising the heterogeneity of invasive lobular carcinomas of the breast

Vargas, A. C., Simpson, P., Jayanthan, J., Lane, A., Reid, L., Evans, E., Porter, A. and Lakhani, S. (2010). Role of breast screening for characterising the heterogeneity of invasive lobular carcinomas of the breast. 28th International Congress of the International-Academy-of-Pathology, Sao Paulo, Brazil, 10-15 October 2010. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

Role of breast screening for characterising the heterogeneity of invasive lobular carcinomas of the breast

2010

Journal Article

Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?

Lakhani, Sunil R., Khanna, Kum K. and Chenevix-Trench, Georgia (2010). Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?. Breast Cancer Research, 12 (2) 104, 104-1-104-2. doi: 10.1186/bcr2483

Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?

2010

Book Chapter

Lobular carcinoma in situ

Da Silva, Leonard, Simpson, Peter T. and Lakhani, Sunil R. (2010). Lobular carcinoma in situ. Management of breast diseases. (pp. 181-199) edited by Ismail Jatoi and M. Kaufmann. Heidelberg: Springer. doi: 10.1007/978-3-540-69743-5_11

Lobular carcinoma in situ

2010

Conference Publication

Distinct pathological characteristics of lobular carcinoma

Lakhani, SR and Simpson, PT (2010). Distinct pathological characteristics of lobular carcinoma. European Breast Cancer Conference, Barcelona Spain, Mar 24, 2010. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/S1359-6349(10)70242-1

Distinct pathological characteristics of lobular carcinoma

2010

Book Chapter

High-risk lesions: ALH/LCIS/ADH

Smart, Chanel E., Furnival, Colin M. and Lakhani, Sunil R. (2010). High-risk lesions: ALH/LCIS/ADH. Kuerer's breast surgical oncology. (pp. 179-187) edited by Henry Mark Kuerer. New York, U.S.A.: McGraw-Hill Medical.

High-risk lesions: ALH/LCIS/ADH

2010

Book Chapter

Lobular carcinoma in situ : Biology and pathology

Simpson, Peter T., Reis-Filho, Jorge S. and Lakhani, Sunil R. (2010). Lobular carcinoma in situ : Biology and pathology. Diseases of the breast. (pp. 333-340) edited by Jay R. Harris, Marc E. Lippman, C. Kent Osborne and Monica Morrow. Philadelphia: Lippencott, Williams & Wilkins.

Lobular carcinoma in situ : Biology and pathology

2010

Journal Article

Breast cancer prognostic classification in the molecular era: The role of histological grade

Rakha, Emad A., Reis-Filho, Jorge S., Baehner, Frederick, Dabbs, David J., Decker, Thomas, Eusebi, Vincenzo, Fox, Stephen B., Ichihara, Shu, Jacquemier, Jocelyne, Lakhani, Sunil R., Palacios, José, Richardson, Andrea L., Schnitt, Stuart J., Schmitt, Fernando C., Tan, Puay-Hoon, Tse, Gary M., Badve, Sunil and Ellis, Ian (2010). Breast cancer prognostic classification in the molecular era: The role of histological grade. Breast Cancer Research, 12 (4) 207, 1-12. doi: 10.1186/bcr2607

Breast cancer prognostic classification in the molecular era: The role of histological grade

2010

Journal Article

Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study

Milne, Roger L., Gaudet, Mia M., Spurdle, Amanda B., Fasching, Peter A., Couch, Fergus J., Benitez, Javier, Arias Perez, Jose Ignacio, Zamora, M. Pilar, Malats, Nuria, dos Santos Silva, Isabel, Gibson, Lorna J., Fletcher, Olivia, Johnson, Nichola, Anton-Culver, Hoda, Ziogas, Argyrios, Figueroa, Jonine, Brinton, Louise, Sherman, Mark E., Lissowska, Jolanta, Hopper, John L., Dite, Gillian S., Apicella, Carmel, Southey, Melissa C., Sigurdson, Alice J., Linet, Martha S., Schonfeld, Sara J., Freedman, D. Michal, Mannermaa, Arto, Kosma, Veli-Matti ... Lakhani, Sunil (2010). Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study. Breast Cancer Research, 12 (6) R110, R110.1-R110.11. doi: 10.1186/bcr2797

Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study

2010

Conference Publication

Shifting phenotypes in primary human mammary epithelial culture

Smart, Chanel E., Saunus, Jodi M., Keith, Patricia, Vargas, Ana Cristina, Malik, Neelam, Clarke, Catherine, Simpson, Peter T. and Lakhani, Sunil R. (2010). Shifting phenotypes in primary human mammary epithelial culture. Sixth International Conference on Hormonal Oncogenesis, Tokyo, Japan, 12-16 September 2010.

Shifting phenotypes in primary human mammary epithelial culture

2009

Conference Publication

Distinctive Expression of Cancer/Testis-X Antigens in a Subset of ER Negative Breast Carcinomas

Grigoriadis, A., Caballe, O. L., Hoek, K. S., da Silva, L., Chen, Y-T, Shin, S. J., Jungbluth, A., Miller, L. D., Cebon, J., Old, L., Lakhani, S. R., Simpson, A. G. and Neville, M. (2009). Distinctive Expression of Cancer/Testis-X Antigens in a Subset of ER Negative Breast Carcinomas. 32nd Annual San Antonio Breast Cancer Symposium, San Antonio Tx, Dec 09-13, 2009. PHILADELPHIA: AMER ASSOC CANCER RESEARCH.

Distinctive Expression of Cancer/Testis-X Antigens in a Subset of ER Negative Breast Carcinomas

2009

Journal Article

Fibroadenoma and intraduct papilloma--a common pathogenesis?

Cummings, Margaret C., Da Silva, Leonard, Papadimos, David J. and Lakhani, Sunil R. (2009). Fibroadenoma and intraduct papilloma--a common pathogenesis?. Virchows Archiv, 455 (3), 271-275. doi: 10.1007/s00428-009-0817-8

Fibroadenoma and intraduct papilloma--a common pathogenesis?

2009

Journal Article

CT-X antigen expression in human breast cancer

Grigoriadis, Anita, Caballero, Otavia L., Hoek, Keith S., da Silva, Leonard, Chen, Yao-Tseng, Shin, Sandra J., Jungbluth, Achim A., Miller, Lance D., Clouston, David, Cebon, Jonathan, Old, Lloyd J., Lakhani, Sunil R., Simpson, Andrew J.G. and Neville, A. Munro Neville (2009). CT-X antigen expression in human breast cancer. Proceedings of the National Academy of Sciences, 106 (32), 13493-13498. doi: 10.1073/pnas.0906840106

CT-X antigen expression in human breast cancer

2009

Journal Article

Cancers in BRCA1 and BRCA2 carriers and in women at high risk for breast cancer: MR imaging and mammographic features

Gilbert, Fiona J., Warren, Ruth M. L., Kwan-Lim, Gek, Thompson, Deborah J., Eeles, Ros A., Evans, D. Gareth, Leach, Martin O., United Kingdom Magnetic Resonance Imaging in Breast Screening (MARIBS) Study Group and Lakhani, S. R. (2009). Cancers in BRCA1 and BRCA2 carriers and in women at high risk for breast cancer: MR imaging and mammographic features. Radiology, 252 (2), 358-368. doi: 10.1148/radiol.2522081032

Cancers in BRCA1 and BRCA2 carriers and in women at high risk for breast cancer: MR imaging and mammographic features

2009

Journal Article

Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma

Shin, Sandra J., Simpson, Peter T., Da Silva, Leonard, Jayanthan, Janani, Reid, Lynne, Lakhani, Sunil R. and Rosen, Paul Peter (2009). Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma. The American Journal of Surgical Pathology, 33 (4), 496-504. doi: 10.1097/PAS.0b013e31818af361

Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma

2009

Journal Article

Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact

Vargas, Ana-Cristina, Lakhani‌, Sunil R. and Simpson, Peter T. (2009). Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact. Future Oncology, 5 (2), 233-243. doi: 10.2217/14796694.5.2.233

Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact

2009

Journal Article

Current and future approach to the pathologist's assessment for targeted therapy in breast cancer

Pakkiri, P, Lakhani, SR and Smart, CE (2009). Current and future approach to the pathologist's assessment for targeted therapy in breast cancer. Pathology, 41 (1), 89-99. doi: 10.1080/00313020802563551

Current and future approach to the pathologist's assessment for targeted therapy in breast cancer