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2008

Journal Article

Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas

Simpson, P. T., Reis-Filho, J. S., Lambros, M. B. K., Jones, C., Steele, D., Mackay, A., Iravani, M., Fenwick, K., Dexter, T., Jones, A., Reid, L., Da Silva, L., Shin, S. J., Hardisson, D., Ashworth, A., Schmitt, F. C., Palacios, J. and Lakhani, S.R. (2008). Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas. Journal of Pathology, 215 (3), 231-244. doi: 10.1002/path.2358

Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas

2008

Journal Article

Aberrant expression of E-cadherin in lobular carcinomas of the breast

DA Silva, L, Parry, S, Reid, L, Keith, P, Waddell, N, Kossai, M, Clarke, C, Lakhani, SR and Simpson, PT (2008). Aberrant expression of E-cadherin in lobular carcinomas of the breast. American Journal of Surgical Pathology, 32 (5), 773-783. doi: 10.1097/PAS.0b013e318158d6c5

Aberrant expression of E-cadherin in lobular carcinomas of the breast

2008

Journal Article

Clinical classification of BRCA1 and BRCA2 DNA sequence variants: The value of cytokeratin profiles and evolutionary analysis - A report from the kConFab Investigators

Spurdle, A.B., Lakhani, S.R., Healey, S., Parry, S., Da Silva, L. M., Brinkworth, R.I., Hopper, J.L., Brown, M.A., Babikyan, D., Chenevix-Trench, G., Tavtigian, S.V. and Goldgar, D.E. (2008). Clinical classification of BRCA1 and BRCA2 DNA sequence variants: The value of cytokeratin profiles and evolutionary analysis - A report from the kConFab Investigators. Journal of Clinical Oncology, 26 (10), 1657-1663. doi: 10.1200/JCO.2007.13.2779

Clinical classification of BRCA1 and BRCA2 DNA sequence variants: The value of cytokeratin profiles and evolutionary analysis - A report from the kConFab Investigators

2008

Journal Article

What's in a cancer syndrome? Genes, phenotype and pathology

Wayte, Nicola, Da Silva, Leonard, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2008). What's in a cancer syndrome? Genes, phenotype and pathology. Pathology, 40 (3), 247-259. doi: 10.1080/00313020801911553

What's in a cancer syndrome? Genes, phenotype and pathology

2008

Conference Publication

Is there molecular evidence for progression of microglandular adenosis to carcinoma: Results of comparative genomic hybridization (CGH) on microdissected lesions

Shin, S. J., Simpson, P. T., Da Silva, L., Mahalinga-Iyer, J., Lakhani, S. R. and Rosen, P. P. (2008). Is there molecular evidence for progression of microglandular adenosis to carcinoma: Results of comparative genomic hybridization (CGH) on microdissected lesions. 97th Annual Meeting of the United States and Canadian Academy of Pathology, Denver, CO, United States, 1-7 March 2008. Nature Publishing Group.

Is there molecular evidence for progression of microglandular adenosis to carcinoma: Results of comparative genomic hybridization (CGH) on microdissected lesions

2008

Journal Article

Pathology in education and practice: a time for integration?

Mortimer, R. and Lakhani, S. (2008). Pathology in education and practice: a time for integration?. Australian Health Review, 32 (2), 319-321. doi: 10.1071/AH080319

Pathology in education and practice: a time for integration?

2007

Journal Article

Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?

Lovelock, Paul K., Spurdle, Amanda B., Mok, Myth T. S., Farrugia, Daniel J., Lakhani, Sunil R., Healey, Sue, Arnold, Stephen, Buchanan, Daniel, kConFab Investigators, Couch, Fergus J., Henderson, Berik R., Goldgar, David E., Tavtigian, Sean V., Chenevix-Trench, Georgia and Brown, Melissa A (2007). Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?. Breast Cancer Research, 9 (6: R82) R82, 1-13. doi: 10.1186/bcr1826

Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?

2007

Journal Article

Mutation analysis of five candidate genes in familial breast cancer

Marsh, Anna, Healey, Sue, Lewis, Aaron, Spurdle, Amanda B., Kedda, Mary Anne, Khanna, Kum Kum, Mann, Graham J., Pupo, Gulietta M., Lakhani, Sunil R. and Chenevix-Trench, Georgia (2007). Mutation analysis of five candidate genes in familial breast cancer. Breast Cancer Research & Treatment, 105 (3), 377-389. doi: 10.1007/s10549-006-9461-z

Mutation analysis of five candidate genes in familial breast cancer

2007

Journal Article

Genome-wide association study identifies novel breast cancer susceptibility loci

Easton, Douglas F., Pooley, Karen A., Dunning, Alison M., Pharoah, Paul D. P., Thompson, Deborah, Ballinger, Dennis G., Struewing, Jeffery P., Morrison, Jonathan, Field, Helen, Luben, Robert, Wareham, Nicholas, Ahmed, Shahana, Healey, Catherine S., Bowman, Richard, SEARCH collaborators, Meyer, Kerstin B., Haiman, Christopher A., Kolonel, Laurence K., Henderson, Brian E., Marchand, Loic Le, Brennan, Paul, Sangrajrang, Suleeporn, Gaborieau, Valerie, Odefrey, Fabrice, Shen, Chen-Yang, Wu, Pei-Ei, Wang, Hui-Chun, Eccles Diana, Evans, D. Gareth ... Ward, Robyn (2007). Genome-wide association study identifies novel breast cancer susceptibility loci. Nature, 447 (7148), 1087-1093. doi: 10.1038/nature05887

Genome-wide association study identifies novel breast cancer susceptibility loci

2007

Journal Article

Demystifying basal-like breast carcinomas

Da Silva, L., Clarke, C. and Lakhani, S.R. (2007). Demystifying basal-like breast carcinomas. Journal of Clinical Pathology, 60 (12), 1328-1332. doi: 10.1136/jcp.2006.041731

Demystifying basal-like breast carcinomas

2007

Journal Article

Comparative molecular pathology of adenoid cystic carcinoma from different sites: A microarray-based CGH analysi

Fulford, L. G., Reis, J. S., Mackay, A., Fenwick, K., Iravani, M., Ashworth, A., Nicholson, A. G., Schmitt, F. C., Simpson, H. W. and Lakhani, S. R. (2007). Comparative molecular pathology of adenoid cystic carcinoma from different sites: A microarray-based CGH analysi. Laboratory Investigation, 87 (Supplement 1s), 305A-306A. doi: 10.1038/sj.labinvest.3700582

Comparative molecular pathology of adenoid cystic carcinoma from different sites: A microarray-based CGH analysi

2007

Journal Article

Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival

Fulford, Laura G., Reis-Filho, Jorge S., Ryder, Ken, Jones, Chris, Gillett, Cheryl E., Hanby, Andrew, Easton, Douglas and Lakhani, Sunil R. (2007). Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival. Breast Cancer Research, 9 (1) R4, 1-11. doi: 10.1186/bcr1636

Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival

2007

Book Chapter

Pathology of ovarian tumors in mutation carriers

Penault-Llorca, Frédérique and Lakhani, Sunil R. (2007). Pathology of ovarian tumors in mutation carriers. Hereditary breast cancer. (pp. 333-344) edited by Claudine Isaacs and Timothy R. Rebbeck. Boca Raton, FL, United States: CRC Press. doi: 10.3109/9781420020366-23

Pathology of ovarian tumors in mutation carriers

2007

Journal Article

In situ carcinoma - can we predict which patient will come back with a recurrence?

Simpson, P.T., Da Silva, L. M and Lakhani, S.R. (2007). In situ carcinoma - can we predict which patient will come back with a recurrence?. Cancer Cell, 12 (5), 409-411. doi: 10.1016/j.ccr.2007.10.026

In situ carcinoma - can we predict which patient will come back with a recurrence?

2007

Conference Publication

Evidence of evolution and intrinsic molecular relationship in a spectrum of morphological variants of invasive lobular carcinoma with variable E-cadherin status

Da Silva, L., Parry, S., Keith, P., Lakhani, S. R. and Simpson, P. (2007). Evidence of evolution and intrinsic molecular relationship in a spectrum of morphological variants of invasive lobular carcinoma with variable E-cadherin status. United States and Canadian Academy of Pathology 2007 Annual Meeting, San Diego, California, 24-30 March, 2007. Baltimore, MD: Nature Publishing.

Evidence of evolution and intrinsic molecular relationship in a spectrum of morphological variants of invasive lobular carcinoma with variable E-cadherin status

2007

Conference Publication

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

Brewster, Brooke, Brooks, Kelly, Brown, Melissa Anne, Clarke, C., Fleming, J. S., French, J. D., Hetherington, Rehan, Lakhani, Sunil, Raghavendra, Ashwini, Rothnagel, Joseph, Smart, Chanel and Wainwright, Brandon (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. Gordon Research Conference: Mammary Gland Biology, Newport, RI, 10-15 June 2007.

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

2007

Conference Publication

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

Smart, C. E., Clarke, C., Brooks, K. M., Raghavendra, A., Brewster, B. L., French, J. D., Hetherington, R., Fleming, J. S., Rothnagel, J. A., Wainwright, B., Lakhani, S. R. and Brown, M. A. (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. Australian Breast Cancer Conference, Melbourne, Australia, 2007.

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

2007

Journal Article

Comparative molecular pathology of adenoid cystic carcinoma from different sites: A microarray-based CGH analysis

Fulford, L. G., Reis, J. S., Mackay, A., Feinwick, K., Iravani, M., Ashworth, A., Nicholson, A. G., Schmitt, F. C., Simpson, R. H. W. and Lakhani, Sunil R. (2007). Comparative molecular pathology of adenoid cystic carcinoma from different sites: A microarray-based CGH analysis. Modern Pathology, 20 (Supplement 2s), 305A-306A. doi: 10.1038/sj.modpathol.3800815

Comparative molecular pathology of adenoid cystic carcinoma from different sites: A microarray-based CGH analysis

2007

Conference Publication

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

Brewster, Brooke, Brooke, Kelly, Brown, Melissa Anne, Clarke, C., Fleming, J. S., French, J. D., Hetherington, Rehan, Lakhani, Sunil, Raghavendra, Ashwini, Rothnagel, Joseph, Smart, Chanel and Wainwright, Brandon (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. kConFab Familial Breast Cancer Conference, Couran Cove, Queensland, 21-24 August 2007.

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

2006

Journal Article

FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas

Reis-Filho, Jorge Sergio, Simpson, Pete T., Turner, Nicholas C., Lambros, Maryou Ballo, Jones, Chris, Mackay, Alan, Grigoriadis, Anita, Sarrio, David, Savage, Kay, Dexter, Tim, Iravani, Marjan, Fenwick, Kerry, Weber, Barbara, Hardisson, David, Schmitt, Fernando Carlos, Palacios, Jose, Lakhani, Sunil R. and Ashworth, Alan (2006). FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clinical Cancer Research, 12 (22), 6652-6662. doi: 10.1158/1078-0432.CCR-06-1164

FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas