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2010 Journal Article HER3 and downstream pathways are involved in colonization of brain metastases from breast cancerDa Silva, Leonard, Simpson, Peter T., Smart, Chanek E., Cocciardi, Sibylle, Waddell, Nic, Lane, Annette, Morrison, Brian J., Vargas, Ana Cristina, Healey, Sue, Beesley, Jonathan, Pakkiri, Pria, Parry, Suzanne, Kurniawan, Nyoman, Reid, Lynne, Keith, Patricia, Faria, Paulo, Pereira, Emilio, Skalova, Alena, Bilous, Michael, Balleine, Rosemary L., Do, Hongdo, Dobrovic, Alexander, Fox, Stephen, Franco, Marcello, Reynolds, Brent, Khanna, Kum Kum, Cummings, Margaret, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2010). HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer. Breast Cancer Research, 12 (4) R46, R46-1-R46-11. doi: 10.1186/bcr2603 |
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2009 Journal Article Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinomaShin, Sandra J., Simpson, Peter T., Da Silva, Leonard, Jayanthan, Janani, Reid, Lynne, Lakhani, Sunil R. and Rosen, Paul Peter (2009). Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma. The American Journal of Surgical Pathology, 33 (4), 496-504. doi: 10.1097/PAS.0b013e31818af361 |
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2009 Journal Article Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impactVargas, Ana-Cristina, Lakhani, Sunil R. and Simpson, Peter T. (2009). Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact. Future Oncology, 5 (2), 233-243. doi: 10.2217/14796694.5.2.233 |
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2009 Journal Article Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosisDa Silva, Leonard, Buck, Lyndall, Simpson, Peter T., Reid, Lynne, McCallum, Naomi, Madigan, Barry J. and Lakhani, Sunil R. (2009). Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis. Virchows Archiv, 454 (1), 107-114. doi: 10.1007/s00428-008-0700-z |
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2008 Journal Article Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomasSimpson, P. T., Reis-Filho, J. S., Lambros, M. B. K., Jones, C., Steele, D., Mackay, A., Iravani, M., Fenwick, K., Dexter, T., Jones, A., Reid, L., Da Silva, L., Shin, S. J., Hardisson, D., Ashworth, A., Schmitt, F. C., Palacios, J. and Lakhani, S.R. (2008). Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas. Journal of Pathology, 215 (3), 231-244. doi: 10.1002/path.2358 |
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2008 Journal Article Aberrant expression of E-cadherin in lobular carcinomas of the breastDA Silva, L, Parry, S, Reid, L, Keith, P, Waddell, N, Kossai, M, Clarke, C, Lakhani, SR and Simpson, PT (2008). Aberrant expression of E-cadherin in lobular carcinomas of the breast. American Journal of Surgical Pathology, 32 (5), 773-783. doi: 10.1097/PAS.0b013e318158d6c5 |
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2007 Journal Article In situ carcinoma - can we predict which patient will come back with a recurrence?Simpson, P.T., Da Silva, L. M and Lakhani, S.R. (2007). In situ carcinoma - can we predict which patient will come back with a recurrence?. Cancer Cell, 12 (5), 409-411. doi: 10.1016/j.ccr.2007.10.026 |
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2007 Journal Article Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapyPierga, J-Y., Reis-Filho, J. S., Cleator, S. J., Dexter, T., MacKay, A., Simpson, P., Fenwick, K., Iravani, M., Salter, J., Hills, M., Jones, C., Ashworth, A., Smith, I. E., Powles, T. and Dowsett, M. (2007). Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy. British Journal of Cancer, 96 (2), 341-351. doi: 10.1038/sj.bjc.6603483 |
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2006 Journal Article FGFR1 emerges as a potential therapeutic target for lobular breast carcinomasReis-Filho, Jorge Sergio, Simpson, Pete T., Turner, Nicholas C., Lambros, Maryou Ballo, Jones, Chris, Mackay, Alan, Grigoriadis, Anita, Sarrio, David, Savage, Kay, Dexter, Tim, Iravani, Marjan, Fenwick, Kerry, Weber, Barbara, Hardisson, David, Schmitt, Fernando Carlos, Palacios, Jose, Lakhani, Sunil R. and Ashworth, Alan (2006). FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clinical Cancer Research, 12 (22), 6652-6662. doi: 10.1158/1078-0432.CCR-06-1164 |
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2006 Journal Article Metaplastic breast carcinomas are basal-like tumoursReis-Filho, J. S., Milanezi, F., Steele, D., Savage, K., Simpson, P. T., Nesland, J. M., Pereira, E. M., Lakhani, S. R. and Schmitt, F. C. (2006). Metaplastic breast carcinomas are basal-like tumours. Histopathology, 49 (1), 10-21. doi: 10.1111/j.1365-2559.2006.02467.x |
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2006 Journal Article Gene expression analysis using filter cDNA microarraysSimpson, Peter, Jones, Chris, Mackay, Alan and Lakhani, Sunil R (2006). Gene expression analysis using filter cDNA microarrays. Methods in molecular medicine, 120, 415-424. |
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2006 Journal Article Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridizationLambros, Maryou B. K., Simpson, Peter T., Jones, Chris, Natrajan, Rachael, Westbury, Charlotte, Steele, Dawn, Savage, Kay, Mackay, Alan, Schmitt, Fernando C., Ashworth, Alan and Reis-Filho, Jorge S. (2006). Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization. Laboratory Investigation, 86 (4), 398-408. doi: 10.1038/labinvest.3700390 |
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2006 Journal Article EGFR amplification and lack of activating mutations in metaplastic breast carcinomasReis-Filho, J. S., Pinheiro, C., Lambros, M. B. K., Milanezi, F., Carvalho, S., Savage, K., Simpson, P. T., Jones, C., Swift, S., Mackay, A., Reis, R. M., Hornick, J. L., Pereira, E. M., Baltazar, F., Fletcher, C. D. M., Ashworth, A., Lakhani, S. R. and Schmitt, F. C. (2006). EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. Journal of Pathology, 209 (4), 445-453. doi: 10.1002/path.2004 |
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2006 Journal Article Expression profiling using cDNA microarraysJones, Chris, Simpson, Peter, Mackay, Alan and Lakhani, Sunil R (2006). Expression profiling using cDNA microarrays. Methods in molecular medicine, 120, 403-414. |
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2005 Journal Article The molecular genetics of breast cancer: The contribution of comparative genomic hybridizationReis-Filho, Jorge S., Simpson, Peter T., Gale, Theodora and Lakhani, Sunil R. (2005). The molecular genetics of breast cancer: The contribution of comparative genomic hybridization. Pathology Research & Practice, 201 (11), 713-725. doi: 10.1016/j.prp.2005.05.013 |
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2005 Journal Article Columnar cell lesions of the breast: The missing link in breast cancer progression? A morphological and molecular analysisSimpson, P. T., Gale, T., Reis-Filho, J. S., Jones, C., Parry, S., Sloane, J. P., Hanby, A., Pinder, S. E., Lee, A. H. S., Humphreys, S., Ellis, I. O. and Lakhani, S. R. (2005). Columnar cell lesions of the breast: The missing link in breast cancer progression? A morphological and molecular analysis. American Journal of Surgical Pathology, 29 (6), 734-746. doi: 10.1097/01.pas.0000157295.93914.3b |
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2005 Journal Article Molecular evolution of breast cancerSimpson, P. T., Reis-Filho, J. S., Gale, T. and Lakhani, S. R. (2005). Molecular evolution of breast cancer. Journal of Pathology, 205 (2), 248-254. doi: 10.1002/path.1691 |
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2005 Journal Article Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entityReis-Filho, J. S., Simpson, P. T., Jones, C., Steele, D., Mackay, A., Iravani, M., Fenwick, K., Valgeirrson, H., Lambros, M., Ashworth, A., Palacios, J., Schmitt, F. and Lakhani, S. R. (2005). Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity. Journal of Pathology, 207 (1), 1-13. doi: 10.1002/path.1806 |
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2005 Journal Article Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: Immunohistochemical and chromogenic in situ hybridization analysisReis-Filho, Jorge S., Milanezi, Fernanda, Carvalho, Silvia, Simpson, Peter T., Steele, Dawn, Savage, Kay, Lambros, Maryou B. K., Pereira, Emilio M., Nesland, John M., Lakhani, Sunil R. and Schmitt, Fernando C. (2005). Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: Immunohistochemical and chromogenic in situ hybridization analysis. Breast Cancer Research, 7 (6) R1028, R1028-R1035. doi: 10.1186/bcr1341 |
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2004 Journal Article Distribution and significance of 14-3-3 sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissueSimpson, Peter T., Gale, Theodora, Reis-Filho, Jorge S, Jones, Chris, Parry, Suzanne, Steele, Dawn, Cossu, Antonio, Budroni, Mario, Palmieri, Giuseppe and Lakhani, Sunil R (2004). Distribution and significance of 14-3-3 sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue. Journal of Pathology, 202 (3), 274-285. doi: 10.1002/path.1530 |