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2011

Journal Article

Application of molecular findings to the diagnosis and management of breast disease: Recent advances and challenges

Simpson, Peter T., Vargas, Ana Christina, Al-Ejeh, Fares, Khanna, Kum Kum, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2011). Application of molecular findings to the diagnosis and management of breast disease: Recent advances and challenges. Human Pathology, 42 (2), 153-165. doi: 10.1016/j.humpath.2010.07.008

Application of molecular findings to the diagnosis and management of breast disease: Recent advances and challenges

2011

Journal Article

Molecular aspects of breast cancer metastasis to the brain

Saunus, Jodi M., Momeny, Majid, Simpson, Peter T., Da Silva, Leonard and Lakhani, Sunil R. (2011). Molecular aspects of breast cancer metastasis to the brain. Genetics Research International, 2011, 219189-1-219189-9. doi: 10.4061/2011/219189

Molecular aspects of breast cancer metastasis to the brain

2011

Journal Article

Molecular classification of breast cancer: Is it time to pack up our microscopes?

Cummings, Margaret C., Chambers, Rachael, Simpson, Peter T. and Lakhani, Sunil R. (2011). Molecular classification of breast cancer: Is it time to pack up our microscopes?. Pathology, 43 (1), 1-8. doi: 10.1097/PAT.0b013e328341e0b5

Molecular classification of breast cancer: Is it time to pack up our microscopes?

2010

Journal Article

Subtypes of familial breast tumours revealed by expression and copy number profiling

Waddell, N, Arnold, J, Cocciardi, S, da Silva, L, Marsh, A, Riley, J, Johnstone, CN, Orloff, M, Assie, G, Eng, C, Reid, L, Keith, P, Yan, M, Fox, S, Devilee, P, Godwin, AK, Hogervorst, FBL, Couch, F, Grimmond, S, Flanagan, JM, Khanna, K, Simpson, PT, Lakhani, SR, Chenevix-Trench, G and kConFab Investigators (2010). Subtypes of familial breast tumours revealed by expression and copy number profiling. Breast Cancer Research And Treatment, 123 (3), 661-677. doi: 10.1007/s10549-009-0653-1

Subtypes of familial breast tumours revealed by expression and copy number profiling

2010

Journal Article

Gene expression profiling of formalin-fixed, paraffin-embedded familial breast tumours using the whole genome-DASL assay

Waddell, Nic, Cocciardi, Sibylle, Johnson, Julie, Healey, Sue, Marsh, Anna, Riley, Joan, da Silva, Leonard, Vargas, Ana Cristina, Reid, Lynne, Simpson, Peter T., Lakhani, Sunil R. and Chenevix-Trench, Georgia (2010). Gene expression profiling of formalin-fixed, paraffin-embedded familial breast tumours using the whole genome-DASL assay. Journal of Pathology, 221 (4), 452-461. doi: 10.1002/path.2728

Gene expression profiling of formalin-fixed, paraffin-embedded familial breast tumours using the whole genome-DASL assay

2010

Journal Article

DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status

Flanagan, James M., Cocciardi, Sibylle, Waddell, Nic, Johnstone, Cameron N., Marsh, Anna, Henderson, Stephen, Simpson, Peter, da Silva, Leonard, kConFab Investigators, Khanna, Kumkum, Lakhani, Sunil, Boshoff, Chris, Chenevix-Trench, Georgia, Brown, Melissa, Cummings, Margaret and Edwards, Stacey (2010). DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. American Journal of Human Genetics, 86 (3), 420-433. doi: 10.1016/j.ajhg.2010.02.008

DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status

2010

Journal Article

Breast pathology: Beyond morphology

Simpson, Peter T., Reis-Filho, Jorge S. and Lakhani, Sunil R. (2010). Breast pathology: Beyond morphology. Seminars in Diagnostic Pathology, 27 (1), 91-96. doi: 10.1053/j.semdp.2009.12.001

Breast pathology: Beyond morphology

2010

Journal Article

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

Da Silva, Leonard, Simpson, Peter T., Smart, Chanek E., Cocciardi, Sibylle, Waddell, Nic, Lane, Annette, Morrison, Brian J., Vargas, Ana Cristina, Healey, Sue, Beesley, Jonathan, Pakkiri, Pria, Parry, Suzanne, Kurniawan, Nyoman, Reid, Lynne, Keith, Patricia, Faria, Paulo, Pereira, Emilio, Skalova, Alena, Bilous, Michael, Balleine, Rosemary L., Do, Hongdo, Dobrovic, Alexander, Fox, Stephen, Franco, Marcello, Reynolds, Brent, Khanna, Kum Kum, Cummings, Margaret, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2010). HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer. Breast Cancer Research, 12 (4) R46, R46-1-R46-11. doi: 10.1186/bcr2603

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

2009

Journal Article

Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma

Shin, Sandra J., Simpson, Peter T., Da Silva, Leonard, Jayanthan, Janani, Reid, Lynne, Lakhani, Sunil R. and Rosen, Paul Peter (2009). Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma. The American Journal of Surgical Pathology, 33 (4), 496-504. doi: 10.1097/PAS.0b013e31818af361

Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma

2009

Journal Article

Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact

Vargas, Ana-Cristina, Lakhani‌, Sunil R. and Simpson, Peter T. (2009). Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact. Future Oncology, 5 (2), 233-243. doi: 10.2217/14796694.5.2.233

Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact

2009

Journal Article

Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis

Da Silva, Leonard, Buck, Lyndall, Simpson, Peter T., Reid, Lynne, McCallum, Naomi, Madigan, Barry J. and Lakhani, Sunil R. (2009). Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis. Virchows Archiv, 454 (1), 107-114. doi: 10.1007/s00428-008-0700-z

Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis

2008

Journal Article

Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas

Simpson, P. T., Reis-Filho, J. S., Lambros, M. B. K., Jones, C., Steele, D., Mackay, A., Iravani, M., Fenwick, K., Dexter, T., Jones, A., Reid, L., Da Silva, L., Shin, S. J., Hardisson, D., Ashworth, A., Schmitt, F. C., Palacios, J. and Lakhani, S.R. (2008). Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas. Journal of Pathology, 215 (3), 231-244. doi: 10.1002/path.2358

Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas

2008

Journal Article

Aberrant expression of E-cadherin in lobular carcinomas of the breast

DA Silva, L, Parry, S, Reid, L, Keith, P, Waddell, N, Kossai, M, Clarke, C, Lakhani, SR and Simpson, PT (2008). Aberrant expression of E-cadherin in lobular carcinomas of the breast. American Journal of Surgical Pathology, 32 (5), 773-783. doi: 10.1097/PAS.0b013e318158d6c5

Aberrant expression of E-cadherin in lobular carcinomas of the breast

2007

Journal Article

In situ carcinoma - can we predict which patient will come back with a recurrence?

Simpson, P.T., Da Silva, L. M and Lakhani, S.R. (2007). In situ carcinoma - can we predict which patient will come back with a recurrence?. Cancer Cell, 12 (5), 409-411. doi: 10.1016/j.ccr.2007.10.026

In situ carcinoma - can we predict which patient will come back with a recurrence?

2007

Journal Article

Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy

Pierga, J-Y., Reis-Filho, J. S., Cleator, S. J., Dexter, T., MacKay, A., Simpson, P., Fenwick, K., Iravani, M., Salter, J., Hills, M., Jones, C., Ashworth, A., Smith, I. E., Powles, T. and Dowsett, M. (2007). Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy. British Journal of Cancer, 96 (2), 341-351. doi: 10.1038/sj.bjc.6603483

Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy

2006

Journal Article

FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas

Reis-Filho, Jorge Sergio, Simpson, Pete T., Turner, Nicholas C., Lambros, Maryou Ballo, Jones, Chris, Mackay, Alan, Grigoriadis, Anita, Sarrio, David, Savage, Kay, Dexter, Tim, Iravani, Marjan, Fenwick, Kerry, Weber, Barbara, Hardisson, David, Schmitt, Fernando Carlos, Palacios, Jose, Lakhani, Sunil R. and Ashworth, Alan (2006). FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clinical Cancer Research, 12 (22), 6652-6662. doi: 10.1158/1078-0432.CCR-06-1164

FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas

2006

Journal Article

EGFR amplification and lack of activating mutations in metaplastic breast carcinomas

Reis-Filho, J. S., Pinheiro, C., Lambros, M. B. K., Milanezi, F., Carvalho, S., Savage, K., Simpson, P. T., Jones, C., Swift, S., Mackay, A., Reis, R. M., Hornick, J. L., Pereira, E. M., Baltazar, F., Fletcher, C. D. M., Ashworth, A., Lakhani, S. R. and Schmitt, F. C. (2006). EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. Journal of Pathology, 209 (4), 445-453. doi: 10.1002/path.2004

EGFR amplification and lack of activating mutations in metaplastic breast carcinomas

2006

Journal Article

Expression profiling using cDNA microarrays

Jones, Chris, Simpson, Peter, Mackay, Alan and Lakhani, Sunil R (2006). Expression profiling using cDNA microarrays. Methods in molecular medicine, 120, 403-414.

Expression profiling using cDNA microarrays

2006

Journal Article

Metaplastic breast carcinomas are basal-like tumours

Reis-Filho, J. S., Milanezi, F., Steele, D., Savage, K., Simpson, P. T., Nesland, J. M., Pereira, E. M., Lakhani, S. R. and Schmitt, F. C. (2006). Metaplastic breast carcinomas are basal-like tumours. Histopathology, 49 (1), 10-21. doi: 10.1111/j.1365-2559.2006.02467.x

Metaplastic breast carcinomas are basal-like tumours

2006

Journal Article

Gene expression analysis using filter cDNA microarrays

Simpson, Peter, Jones, Chris, Mackay, Alan and Lakhani, Sunil R (2006). Gene expression analysis using filter cDNA microarrays. Methods in molecular medicine, 120, 415-424.

Gene expression analysis using filter cDNA microarrays