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2021 Journal Article Invasive lobular carcinoma of the breast: the increasing importance of this special subtypeMcCart Reed, Amy E., Kalinowski, Lauren, Simpson, Peter T. and Lakhani, Sunil R. (2021). Invasive lobular carcinoma of the breast: the increasing importance of this special subtype. Breast Cancer Research, 23 (1) 6, 6. doi: 10.1186/s13058-020-01384-6 |
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2020 Journal Article Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer-insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model systemWafai, Razan, Williams, Elizabeth D., de Souza, Emma, Simpson, Peter T., Reed, Amy E. McCart, Kutasovic, Jamie R., Waltham, Mark, Snell, Cameron E., Blick, Tony, Thompson, Erik W. and Hugo, Honor J. (2020). Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer-insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system. Breast Cancer Research, 22 (1) 136, 136. doi: 10.1186/s13058-020-01366-8 |
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2020 Journal Article Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSigRubanova, Yulia, Shi, Ruian, Harrigan, Caitlin F., Li, Roujia, Wintersinger, Jeff, Sahin, Nil, Deshwar, Amit G., Dentro, Stefan C., Leshchiner, Ignaty, Gerstung, Moritz, Jolly, Clemency, Haase, Kerstin, Tarabichi, Maxime, Wintersinger, Jeff, Deshwar, Amit G., Yu, Kaixian, Gonzalez, Santiago, Rubanova, Yulia, Macintyre, Geoff, Adams, David J., Anur, Pavana, Beroukhim, Rameen, Boutros, Paul C., Bowtell, David D., Campbell, Peter J., Cao, Shaolong, Christie, Elizabeth L., Cmero, Marek, Cun, Yupeng ... PCAWG Consortium (2020). Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig. Nature Communications, 11 (1) 731, 1-12. doi: 10.1038/s41467-020-14352-7 |
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2020 Journal Article Divergent mutational processes distinguish hypoxic and normoxic tumoursBhandari, Vinayak, Li, Constance H., Bristow, Robert G., Boutros, Paul C., Aaltonen, Lauri A., Abascal, Federico, Abeshouse, Adam, Aburatani, Hiroyuki, Adams, David J., Agrawal, Nishant, Ahn, Keun Soo, Ahn, Sung-Min, Aikata, Hiroshi, Akbani, Rehan, Akdemir, Kadir C., Al-Ahmadie, Hikmat, Al-Sedairy, Sultan T., Al-Shahrour, Fatima, Alawi, Malik, Albert, Monique, Aldape, Kenneth, Alexandrov, Ludmil B., Ally, Adrian, Alsop, Kathryn, Alvarez, Eva G., Amary, Fernanda, Amin, Samirkumar B., Aminou, Brice, Ammerpohl, Ole ... PCAWG Consortium (2020). Divergent mutational processes distinguish hypoxic and normoxic tumours. Nature Communications, 11 (1) 737. doi: 10.1038/s41467-019-14052-x |
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2020 Journal Article Inferring structural variant cancer cell fractionCmero, Marek, Yuan, Ke, Ong, Cheng Soon, Schröder, Jan, Adams, David J., Anur, Pavana, Beroukhim, Rameen, Boutros, Paul C., Bowtell, David D. L., Campbell, Peter J., Cao, Shaolong, Christie, Elizabeth L., Cun, Yupeng, Dawson, Kevin J., Demeulemeester, Jonas, Dentro, Stefan C., Deshwar, Amit G., Donmez, Nilgun, Drews, Ruben M., Eils, Roland, Fan, Yu, Fittall, Matthew W., Garsed, Dale W., Gerstung, Moritz, Getz, Gad, Gonzalez, Santiago, Ha, Gavin, Haase, Kerstin, Imielinski, Marcin ... von Mering, Christian (2020). Inferring structural variant cancer cell fraction. Nature Communications, 11 (1) 730. doi: 10.1038/s41467-020-14351-8 |
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2020 Journal Article Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1Kalaw, Emarene, Lim, Malcolm, Kutasovic, Jamie R., Sokolova, Anna, Taege, Lucinda, Johnstone, Kate, Bennett, James, Saunus, Jodi M., Niland, Colleen, Ferguson, Kaltin, Gresshoff, Irma, Bettington, Mark, Pathmanathan, Nirmala, Tse, Gary M., Papadimos, David, Pathmanathan, Rajadurai, Harris, Gavin, Yamaguchi, Rin, Tan, Puay Hoon, Fox, Stephen, O’Toole, Sandra A., Simpson, Peter T., Lakhani, Sunil R. and McCart Reed, Amy E. (2020). Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1. British Journal of Cancer, 123 (11), 1665-1672. doi: 10.1038/s41416-020-01065-3 |
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2020 Journal Article Phenotypic drift in metastatic progression of breast cancer: a case report with histologically heterogeneous lesions that are clonally relatedKutasovic, Jamie R., McCart Reed, Amy E., Sokolova, Anna, Jayanthan, Janani, Da Silva, Leonard, Simpson, Peter T. and Lakhani, Sunil R. (2020). Phenotypic drift in metastatic progression of breast cancer: a case report with histologically heterogeneous lesions that are clonally related. Clinical Case Reports, 8 (12) ccr3.3257, 2725-2731. doi: 10.1002/ccr3.3257 |
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2020 Journal Article Using whole-genome sequencing data to derive the homologous recombination deficiency scoresde Luca, Xavier M., Newell, Felicity, Kazakoff, Stephen H., Hartel, Gunter, McCart Reed, Amy E., Holmes, Oliver, Xu, Qinying, Wood, Scott, Leonard, Conrad, Pearson, John V., Lakhani, Sunil R., Waddell, Nicola, Nones, Katia and Simpson, Peter T. (2020). Using whole-genome sequencing data to derive the homologous recombination deficiency scores. npj Breast Cancer, 6 (1) 33, 33. doi: 10.1038/s41523-020-0172-0 |
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2020 Journal Article Clinicopathologic significance of nuclear HER4 and phospho-YAP(S127) in human breast cancers and matching brain metastasesKalita-de Croft, Priyakshi, Lim, Malcolm, Chittoory, Haarika, de Luca, Xavier M., Kutasovic, Jamie R., Day, Bryan W., Al-Ejeh, Fares, Simpson, Peter T., McCart Reed, Amy E., Lakhani, Sunil R. and Saunus, Jodi M. (2020). Clinicopathologic significance of nuclear HER4 and phospho-YAP(S127) in human breast cancers and matching brain metastases. Therapeutic Advances in Medical Oncology, 12 1758835920946259, 175883592094625. doi: 10.1177/1758835920946259 |
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2020 Conference Publication Designing retrospective analysis of examination items for medical students in clinical science categorisation by Bloom’s Taxonomy, clinical relevance and student perceptionsLi, Joan, Reddy, Venkat, Steele, Megan, Forster, Ashlee, Oancea, Ilulia, Midwinter, Mark, Aland, Claire, Pillai, Suja, Simpson, Peter, Babri, Saleem and Barry, Ben (2020). Designing retrospective analysis of examination items for medical students in clinical science categorisation by Bloom’s Taxonomy, clinical relevance and student perceptions. ANZAHPE2020, Melbourne, VIC Australia, 12-15 July 2020. |
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2020 Journal Article Association of sperm-associated antigen 5 and treatment response in patients with estrogen receptor-positive breast cancerAbdel-Fatah, Tarek M. A., Ball, Graham R., Thangavelu, Pulari U., Reid, Lynne E., McCart Reed, Amy E., Saunus, Jodi M., Duijf, Pascal H. G., Simpson, Peter T., Lakhani, Sunil R., Pongor, Lorinc, Gyorffy, Balázs, Moseley, Paul M., Green, Andrew R., Pockley, Alan G., Caldas, Carlos, Ellis, Ian O. and Chan, Stephen Y. T. (2020). Association of sperm-associated antigen 5 and treatment response in patients with estrogen receptor-positive breast cancer. JAMA Network Open, 3 (7) e209486, e209486. doi: 10.1001/jamanetworkopen.2020.9486 |
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2020 Journal Article Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancerBaker, Laura A., Holliday, Holly, Roden, Daniel, Krisp, Christoph, Wu, Sunny Z., Junankar, Simon, Serandour, Aurelien A., Mohammed, Hisham, Nair, Radhika, Sankaranarayanan, Geetha, Law, Andrew M. K., McFarland, Andrea, Simpson, Peter T., Lakhani, Sunil, Dodson, Eoin, Selinger, Christina, Anderson, Lyndal, Samimi, Goli, Hacker, Neville F., Lim, Elgene, Ormandy, Christopher J., Naylor, Matthew J., Simpson, Kaylene, Nikolic, Iva, O'Toole, Sandra, Kaplan, Warren, Cowley, Mark J., Carroll, Jason S., Molloy, Mark and Swarbrick, Alexander (2020). Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer. Breast Cancer Research , 22 (1) 63, 63. doi: 10.1186/s13058-020-01306-6 |
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2020 Journal Article Digital spatial profiling application in breast cancer: a user’s perspectiveMcCart Reed, Amy E., Bennett, James, Kutasovic, Jamie R., Kalaw, Emarene, Ferguson, Kaltin, Yeong, Joe, Simpson, Peter T. and Lakhani, Sunil R. (2020). Digital spatial profiling application in breast cancer: a user’s perspective. Virchows Archiv, 477 (6), 885-890. doi: 10.1007/s00428-020-02821-9 |
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2020 Conference Publication Characterising clinicopathological and biological parameters predictive of outcome for patients diagnosed with invasive lobular carcinomaSimpson, P., Reed, A. McCart, Kutasovic, J., Coorey, C., Kuo, L., Nguyen, H., Pei, W., Ong, J., Sokolova, A., Evans, E., Porter, A. and Lakhani, S. (2020). Characterising clinicopathological and biological parameters predictive of outcome for patients diagnosed with invasive lobular carcinoma. ESMO Breast Cancer Virtual Meeting, Online, 23-24 May 2020. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.annonc.2020.03.186 |
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2020 Journal Article Morphologic and Genomic Heterogeneity in the Evolution and Progression of Breast CancerKutasovic, Jamie R., McCart Reed, Amy E., Sokolova, Anna, Lakhani, Sunil R. and Simpson, Peter T. (2020). Morphologic and Genomic Heterogeneity in the Evolution and Progression of Breast Cancer. Cancers, 12 (4) 848, 848. doi: 10.3390/cancers12040848 |
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2020 Journal Article Butler enables rapid cloud-based analysis of thousands of human genomesYakneen, Sergei, Waszak, Sebastian M., Gertz, Michael, Korbel, Jan O., Aminou, Brice, Bartolome, Javier, Boroevich, Keith A., Boyce, Rich, Brooks, Angela N., Buchanan, Alex, Buchhalter, Ivo, Butler, Adam P., Byrne, Niall J., Cafferkey, Andy, Campbell, Peter J., Chen, Zhaohong, Cho, Sunghoon, Choi, Wan, Clapham, Peter, Davis-Dusenbery, Brandi N., De La Vega, Francisco M., Demeulemeester, Jonas, Dow, Michelle T., Dursi, Lewis Jonathan, Eils, Juergen, Eils, Roland, Ellrott, Kyle, Farcas, Claudiu, Favero, Francesco ... von Mering, Christian (2020). Butler enables rapid cloud-based analysis of thousands of human genomes. Nature Biotechnology, 38 (3), 288-292. doi: 10.1038/s41587-019-0360-3 |
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2020 Journal Article The landscape of viral associations in human cancersZapatka, Marc, Borozan, Ivan, Brewer, Daniel S., Iskar, Murat, Grundhoff, Adam, Alawi, Malik, Desai, Nikita, Sültmann, Holger, Moch, Holger, Alawi, Malik, Borozan, Ivan, Cooper, Colin S., Desai, Nikita, Eils, Roland, Ferretti, Vincent, Grundhoff, Adam, Iskar, Murat, Kleinheinz, Kortine, Lichter, Peter, Nakagawa, Hidewaki, Ojesina, Akinyemi I., Pedamallu, Chandra Sekhar, Schlesner, Matthias, Su, Xiaoping, Zapatka, Marc, Cooper, Colin S., Eils, Roland, Ferretti, Vincent, Lichter, Peter ... von Mering, Christian (2020). The landscape of viral associations in human cancers. Nature Genetics, 52 (3), 320-330. doi: 10.1038/s41588-019-0558-9 |
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2020 Journal Article Pan-cancer analysis of whole genomesCampbell, Peter J., Getz, Gad, Korbel, Jan O., Stuart, Joshua M., Jennings, Jennifer L., Stein, Lincoln D., Perry, Marc D., Nahal-Bose, Hardeep K., Ouellette, B. F. Francis, Li, Constance H., Rheinbay, Esther, Nielsen, G. Petur, Sgroi, Dennis C., Wu, Chin-Lee, Faquin, William C., Deshpande, Vikram, Boutros, Paul C., Lazar, Alexander J., Hoadley, Katherine A., Louis, David N., Dursi, L. Jonathan, Yung, Christina K., Bailey, Matthew H., Saksena, Gordon, Raine, Keiran M., Buchhalter, Ivo, Kleinheinz, Kortine, Schlesner, Matthias, Zhang, Junjun ... Hamdy, Freddie C. (2020). Pan-cancer analysis of whole genomes. Nature, 578 (7793), 82-93. doi: 10.1038/s41586-020-1969-6 |
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2020 Journal Article Genomic basis for RNA alterations in cancerCalabrese, Claudia, Davidson, Natalie R., Demircioğlu, Deniz, Fonseca, Nuno A., He, Yao, Kahles, André, Lehmann, Kjong-Van, Liu, Fenglin, Shiraishi, Yuichi, Soulette, Cameron M., Urban, Lara, Greger, Liliana, Li, Siliang, Liu, Dongbing, Perry, Marc D., Xiang, Qian, Zhang, Fan, Zhang, Junjun, Bailey, Peter, Erkek, Serap, Hoadley, Katherine A., Hou, Yong, Huska, Matthew R., Kilpinen, Helena, Korbel, Jan O., Marin, Maximillian G., Markowski, Julia, Nandi, Tannistha, Pan-Hammarström, Qiang ... von Mering, Christian (2020). Genomic basis for RNA alterations in cancer. Nature, 578 (7793), 129-136. doi: 10.1038/s41586-020-1970-0 |
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2020 Journal Article The repertoire of mutational signatures in human cancerAlexandrov, Ludmil B., Kim, Jaegil, Haradhvala, Nicholas J., Mi, Ni Huang, Ng, Alvin Wei Tian, Yang, Wu, Boot, Arnoud, Covington, Kyle R., Gordenin, Dmitry A., Bergstrom, Erik N., Ashiqul Islam, S. M., Lopez-Bigas, Nuria, Klimczak, Leszek J., McPherson, John R., Morganella, Sandro, Sabarinathan, Radhakrishnan, Wheeler, David A., Mustonen, Ville, Getz, Gad, Rozen, Steven G., Stratton, Michael R., Boutros, Paul, Chan, Kin, Fujimoto, Akihiro, Kazanov, Marat, Lawrence, Michael, Martincorena, Iñigo, Nakagawa, Hidewaki, Polak, Paz ... von Mering, Christian (2020). The repertoire of mutational signatures in human cancer. Nature, 578 (7793), 94-101. doi: 10.1038/s41586-020-1943-3 |