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2010

Journal Article

DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status

Flanagan, James M., Cocciardi, Sibylle, Waddell, Nic, Johnstone, Cameron N., Marsh, Anna, Henderson, Stephen, Simpson, Peter, da Silva, Leonard, kConFab Investigators, Khanna, Kumkum, Lakhani, Sunil, Boshoff, Chris, Chenevix-Trench, Georgia, Brown, Melissa, Cummings, Margaret and Edwards, Stacey (2010). DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. American Journal of Human Genetics, 86 (3), 420-433. doi: 10.1016/j.ajhg.2010.02.008

DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status

2010

Journal Article

Breast pathology: Beyond morphology

Simpson, Peter T., Reis-Filho, Jorge S. and Lakhani, Sunil R. (2010). Breast pathology: Beyond morphology. Seminars in Diagnostic Pathology, 27 (1), 91-96. doi: 10.1053/j.semdp.2009.12.001

Breast pathology: Beyond morphology

2010

Conference Publication

Distinct pathological characteristics of lobular carcinoma

Lakhani, SR and Simpson, PT (2010). Distinct pathological characteristics of lobular carcinoma. European Breast Cancer Conference, Barcelona Spain, Mar 24, 2010. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/S1359-6349(10)70242-1

Distinct pathological characteristics of lobular carcinoma

2010

Book Chapter

Lobular carcinoma in situ : Biology and pathology

Simpson, Peter T., Reis-Filho, Jorge S. and Lakhani, Sunil R. (2010). Lobular carcinoma in situ : Biology and pathology. Diseases of the breast. (pp. 333-340) edited by Jay R. Harris, Marc E. Lippman, C. Kent Osborne and Monica Morrow. Philadelphia: Lippencott, Williams & Wilkins.

Lobular carcinoma in situ : Biology and pathology

2010

Conference Publication

Shifting phenotypes in primary human mammary epithelial culture

Smart, Chanel E., Saunus, Jodi M., Keith, Patricia, Vargas, Ana Cristina, Malik, Neelam, Clarke, Catherine, Simpson, Peter T. and Lakhani, Sunil R. (2010). Shifting phenotypes in primary human mammary epithelial culture. Sixth International Conference on Hormonal Oncogenesis, Tokyo, Japan, 12-16 September 2010.

Shifting phenotypes in primary human mammary epithelial culture

2010

Conference Publication

Role of breast screening for characterising the heterogeneity of invasive lobular carcinomas of the breast

Vargas, A. C., Simpson, P., Jayanthan, J., Lane, A., Reid, L., Evans, E., Porter, A. and Lakhani, S. (2010). Role of breast screening for characterising the heterogeneity of invasive lobular carcinomas of the breast. 28th International Congress of the International-Academy-of-Pathology, Sao Paulo, Brazil, 10-15 October 2010. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

Role of breast screening for characterising the heterogeneity of invasive lobular carcinomas of the breast

2010

Book Chapter

Lobular carcinoma in situ

Da Silva, Leonard, Simpson, Peter T. and Lakhani, Sunil R. (2010). Lobular carcinoma in situ. Management of breast diseases. (pp. 181-199) edited by Ismail Jatoi and M. Kaufmann. Heidelberg: Springer. doi: 10.1007/978-3-540-69743-5_11

Lobular carcinoma in situ

2010

Journal Article

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

Da Silva, Leonard, Simpson, Peter T., Smart, Chanek E., Cocciardi, Sibylle, Waddell, Nic, Lane, Annette, Morrison, Brian J., Vargas, Ana Cristina, Healey, Sue, Beesley, Jonathan, Pakkiri, Pria, Parry, Suzanne, Kurniawan, Nyoman, Reid, Lynne, Keith, Patricia, Faria, Paulo, Pereira, Emilio, Skalova, Alena, Bilous, Michael, Balleine, Rosemary L., Do, Hongdo, Dobrovic, Alexander, Fox, Stephen, Franco, Marcello, Reynolds, Brent, Khanna, Kum Kum, Cummings, Margaret, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2010). HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer. Breast Cancer Research, 12 (4) R46, R46-1-R46-11. doi: 10.1186/bcr2603

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

2009

Journal Article

Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma

Shin, Sandra J., Simpson, Peter T., Da Silva, Leonard, Jayanthan, Janani, Reid, Lynne, Lakhani, Sunil R. and Rosen, Paul Peter (2009). Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma. The American Journal of Surgical Pathology, 33 (4), 496-504. doi: 10.1097/PAS.0b013e31818af361

Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma

2009

Journal Article

Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact

Vargas, Ana-Cristina, Lakhani‌, Sunil R. and Simpson, Peter T. (2009). Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact. Future Oncology, 5 (2), 233-243. doi: 10.2217/14796694.5.2.233

Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact

2009

Journal Article

Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis

Da Silva, Leonard, Buck, Lyndall, Simpson, Peter T., Reid, Lynne, McCallum, Naomi, Madigan, Barry J. and Lakhani, Sunil R. (2009). Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis. Virchows Archiv, 454 (1), 107-114. doi: 10.1007/s00428-008-0700-z

Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis

2008

Journal Article

Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas

Simpson, P. T., Reis-Filho, J. S., Lambros, M. B. K., Jones, C., Steele, D., Mackay, A., Iravani, M., Fenwick, K., Dexter, T., Jones, A., Reid, L., Da Silva, L., Shin, S. J., Hardisson, D., Ashworth, A., Schmitt, F. C., Palacios, J. and Lakhani, S.R. (2008). Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas. Journal of Pathology, 215 (3), 231-244. doi: 10.1002/path.2358

Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas

2008

Journal Article

Aberrant expression of E-cadherin in lobular carcinomas of the breast

DA Silva, L, Parry, S, Reid, L, Keith, P, Waddell, N, Kossai, M, Clarke, C, Lakhani, SR and Simpson, PT (2008). Aberrant expression of E-cadherin in lobular carcinomas of the breast. American Journal of Surgical Pathology, 32 (5), 773-783. doi: 10.1097/PAS.0b013e318158d6c5

Aberrant expression of E-cadherin in lobular carcinomas of the breast

2008

Conference Publication

Is there molecular evidence for progression of microglandular adenosis to carcinoma: Results of comparative genomic hybridization (CGH) on microdissected lesions

Shin, S. J., Simpson, P. T., Da Silva, L., Mahalinga-Iyer, J., Lakhani, S. R. and Rosen, P. P. (2008). Is there molecular evidence for progression of microglandular adenosis to carcinoma: Results of comparative genomic hybridization (CGH) on microdissected lesions. 97th Annual Meeting of the United States and Canadian Academy of Pathology, Denver, CO, United States, 1-7 March 2008. Nature Publishing Group.

Is there molecular evidence for progression of microglandular adenosis to carcinoma: Results of comparative genomic hybridization (CGH) on microdissected lesions

2007

Journal Article

Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy

Pierga, J-Y., Reis-Filho, J. S., Cleator, S. J., Dexter, T., MacKay, A., Simpson, P., Fenwick, K., Iravani, M., Salter, J., Hills, M., Jones, C., Ashworth, A., Smith, I. E., Powles, T. and Dowsett, M. (2007). Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy. British Journal of Cancer, 96 (2), 341-351. doi: 10.1038/sj.bjc.6603483

Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy

2007

Journal Article

In situ carcinoma - can we predict which patient will come back with a recurrence?

Simpson, P.T., Da Silva, L. M and Lakhani, S.R. (2007). In situ carcinoma - can we predict which patient will come back with a recurrence?. Cancer Cell, 12 (5), 409-411. doi: 10.1016/j.ccr.2007.10.026

In situ carcinoma - can we predict which patient will come back with a recurrence?

2007

Conference Publication

Evidence of evolution and intrinsic molecular relationship in a spectrum of morphological variants of invasive lobular carcinoma with variable E-cadherin status

Da Silva, L., Parry, S., Keith, P., Lakhani, S. R. and Simpson, P. (2007). Evidence of evolution and intrinsic molecular relationship in a spectrum of morphological variants of invasive lobular carcinoma with variable E-cadherin status. United States and Canadian Academy of Pathology 2007 Annual Meeting, San Diego, California, 24-30 March, 2007. Baltimore, MD: Nature Publishing.

Evidence of evolution and intrinsic molecular relationship in a spectrum of morphological variants of invasive lobular carcinoma with variable E-cadherin status

2006

Journal Article

FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas

Reis-Filho, Jorge Sergio, Simpson, Pete T., Turner, Nicholas C., Lambros, Maryou Ballo, Jones, Chris, Mackay, Alan, Grigoriadis, Anita, Sarrio, David, Savage, Kay, Dexter, Tim, Iravani, Marjan, Fenwick, Kerry, Weber, Barbara, Hardisson, David, Schmitt, Fernando Carlos, Palacios, Jose, Lakhani, Sunil R. and Ashworth, Alan (2006). FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clinical Cancer Research, 12 (22), 6652-6662. doi: 10.1158/1078-0432.CCR-06-1164

FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas

2006

Conference Publication

Unlocking pathology archives for molecular genetic studies: A reliable method to generate probes for chromogenic and fluorescent in situ hybridisation

Lambros, M. B. K., Simpson, P. T., Jones, C., Natrajan, R., Westbury, C., Steele, D., Savage, K., MacKay, A., Schmitt, F. C., Ashworth, A. and Reis-Filho, J. S. (2006). Unlocking pathology archives for molecular genetic studies: A reliable method to generate probes for chromogenic and fluorescent in situ hybridisation. 26th International Congress of the International Academy of Pathology, Montreal, Canada, 16-21 September 2006. Nature Publishing Group.

Unlocking pathology archives for molecular genetic studies: A reliable method to generate probes for chromogenic and fluorescent in situ hybridisation

2006

Journal Article

Gene expression analysis using filter cDNA microarrays

Simpson, Peter, Jones, Chris, Mackay, Alan and Lakhani, Sunil R (2006). Gene expression analysis using filter cDNA microarrays. Methods in molecular medicine, 120, 415-424.

Gene expression analysis using filter cDNA microarrays