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2020

Journal Article

Amoxicillin-clavulanate dosing in the intensive care unit: the additive effect of renal replacement therapy in a patient with normal kidney function

Lonsdale, Dagan Osborne, Lipman, Jeffrey, Livermore, Amelia, McWhinney, Brett, Ungerer, Jacobus P.J. and Roberts, Jason A. (2020). Amoxicillin-clavulanate dosing in the intensive care unit: the additive effect of renal replacement therapy in a patient with normal kidney function. Chemotherapy, 64 (4), 1-4. doi: 10.1159/000505057

Amoxicillin-clavulanate dosing in the intensive care unit: the additive effect of renal replacement therapy in a patient with normal kidney function

2020

Journal Article

Finding the relevance of antimicrobial stewardship for cystic fibrosis

Cogen, Jonathan D., Kahl, Barbara C., Maples, Holly, McColley, Susanna A., Roberts, Jason A., Winthrop, Kevin L., Morris, Andrew M., Holmes, Alison, Flume, Patrick A., VanDevanter, Donald R., Waters, Valerie, Muhlebach, Marianne S., Elborn, J. Stuart, Saiman, Lisa and Bell, Scott C. (2020). Finding the relevance of antimicrobial stewardship for cystic fibrosis. Journal of Cystic Fibrosis, 19 (4), 511-520. doi: 10.1016/j.jcf.2020.02.012

Finding the relevance of antimicrobial stewardship for cystic fibrosis

2020

Journal Article

β-Lactam pharmacodynamics in Gram-negative bloodstream infections in the critically ill

Wong, Gloria, Taccone, Fabio, Villois, Paola, Scheetz, Marc H., Rhodes, Nathaniel J., Briscoe, Scott, McWhinney, Brett, Nunez-Nunez, Maria, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A. (2020). β-Lactam pharmacodynamics in Gram-negative bloodstream infections in the critically ill. Journal of Antimicrobial Chemotherapy, 75 (2), 429-433. doi: 10.1093/jac/dkz437

β-Lactam pharmacodynamics in Gram-negative bloodstream infections in the critically ill

2020

Journal Article

The challenge of quantifying and managing pharmacokinetic variability of beta-lactams in the critically ill

Crass, Ryan L., Williams, Paul and Roberts, Jason A. (2020). The challenge of quantifying and managing pharmacokinetic variability of beta-lactams in the critically ill. Anaesthesia Critical Care and Pain Medicine, 39 (1), 27-29. doi: 10.1016/j.accpm.2019.12.008

The challenge of quantifying and managing pharmacokinetic variability of beta-lactams in the critically ill

2020

Journal Article

Oral fosfomycin efficacy with variable urinary exposures following single and multiple doses against Enterobacterales: the importance of heteroresistance on growth outcome

Abbott, Iain J., van Gorp, Elke, Wijma, Rixt A., Meletiadis, Joseph, Roberts, Jason A., Mouton, Johan W. and Peleg, Anton Y. (2020). Oral fosfomycin efficacy with variable urinary exposures following single and multiple doses against Enterobacterales: the importance of heteroresistance on growth outcome. Antimicrobial Agents and Chemotherapy, 64 (3) e01982-19. doi: 10.1128/aac.01982-19

Oral fosfomycin efficacy with variable urinary exposures following single and multiple doses against Enterobacterales: the importance of heteroresistance on growth outcome

2020

Journal Article

A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration. Antimicrobial Agents and Chemotherapy, 64 (1) e01655. doi: 10.1128/aac.01655-19

A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration

2020

Journal Article

Linguistic and cultural adaptation to the Portuguese language of antimicrobial dose adjustment software

Silva, Samuel Dutra da, Alves, Geisa Cristina da Silva, Chequer, Farah Maria Drumond, Farkas, Andras, Daróczi, Gergely, Roberts, Jason A. and Sanches, Cristina (2020). Linguistic and cultural adaptation to the Portuguese language of antimicrobial dose adjustment software. Einstein (São Paulo), 18 eAO5023, 1-8. doi: 10.31744/einstein_journal/2020ao5023

Linguistic and cultural adaptation to the Portuguese language of antimicrobial dose adjustment software

2020

Journal Article

Software for dose adjustment of antimicrobials. Implications for plasma concentrations and pratical limitations

Alves, Geisa Cristina da Silva, Silva, Samuel Dutra da, Chequer, Farah Maria Drumond, Castro, Whocely Victor de, Baldoni, André Oliveira, Farkas, Andras, Daróczi, Gergely, Roberts, Jason Alexander and Sanches, Cristina (2020). Software for dose adjustment of antimicrobials. Implications for plasma concentrations and pratical limitations. Einstein, 18 eCE5858, 1-2. doi: 10.31744/einstein_journal/2020ce5858

Software for dose adjustment of antimicrobials. Implications for plasma concentrations and pratical limitations

2020

Journal Article

The pharmacokinetics of meropenem and piperacillin-tazobactam during sustained low efficiency haemodiafiltration (SLED-HDF)

Donnellan, Sine, Wright, Daniel F. B., Roberts, Jason A., Duffull, Stephen B., Schollum, John B. W., Putt, Tracey L., Wallis, Steven C. and Walker, Robert J. (2020). The pharmacokinetics of meropenem and piperacillin-tazobactam during sustained low efficiency haemodiafiltration (SLED-HDF). European Journal of Clinical Pharmacology, 76 (2), 239-247. doi: 10.1007/s00228-019-02792-0

The pharmacokinetics of meropenem and piperacillin-tazobactam during sustained low efficiency haemodiafiltration (SLED-HDF)

2020

Journal Article

Meropenem-tobramycin combination regimens combat carbapenem-resistant Pseudomonas aeruginosa in the hollow-fiber infection model simulating augmented renal clearance in critically ill patients

Yadav, Rajbharan, Bergen, Phillip J., Rogers, Kate E., Kirkpatrick, Carl M. J., Wallis, Steven C., Huang, Yuling, Bulitta, Jürgen B., Paterson, David L., Lipman, Jeffrey, Nation, Roger L., Roberts, Jason A. and Landersdorfer, Cornelia B. (2020). Meropenem-tobramycin combination regimens combat carbapenem-resistant Pseudomonas aeruginosa in the hollow-fiber infection model simulating augmented renal clearance in critically ill patients. Antimicrobial Agents and Chemotherapy, 64 (1) e01679-19. doi: 10.1128/aac.01679-19

Meropenem-tobramycin combination regimens combat carbapenem-resistant Pseudomonas aeruginosa in the hollow-fiber infection model simulating augmented renal clearance in critically ill patients

2020

Journal Article

Pharmacokinetic/pharmacodynamic adequacy of polymyxin B against extensively drug-resistant Gram-negative bacteria in critically ill, general ward and cystic fibrosis patient populations

Xie, Jiao, Roberts, Jason A., Lipman, Jeffrey, Cai, Yan, Wang, Haitao, Zhao, Nuannuan, Xu, Xiaona, Yang, Shan, Li, Youjia and Zhang, Kanghuai (2020). Pharmacokinetic/pharmacodynamic adequacy of polymyxin B against extensively drug-resistant Gram-negative bacteria in critically ill, general ward and cystic fibrosis patient populations. International Journal of Antimicrobial Agents, 55 (6) 105943, 105943. doi: 10.1016/j.ijantimicag.2020.105943

Pharmacokinetic/pharmacodynamic adequacy of polymyxin B against extensively drug-resistant Gram-negative bacteria in critically ill, general ward and cystic fibrosis patient populations

2019

Journal Article

Ceftolozane–tazobactam in an elastomeric infusion device for ambulatory care: an in vitro stability study

Raby, Edward, Naicker, Saiyuri, Sime, Fekade Bruck, Manning, Laurens, Wallis, Steven C., Pandey, Saurabh and Roberts, Jason A. (2019). Ceftolozane–tazobactam in an elastomeric infusion device for ambulatory care: an in vitro stability study. European Journal of Hospital Pharmacy, 27 (e1) e19002093, e84-e86. doi: 10.1136/ejhpharm-2019-002093

Ceftolozane–tazobactam in an elastomeric infusion device for ambulatory care: an in vitro stability study

2019

Journal Article

Pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN)

Ranganathan, Dwarakanathan, Abdul-Aziz, Mohd H., John, George T., McWhinney, Brett C., Fassett, Robert G., Healy, Helen, Kubler, Paul, Lim, Aaron, Lipman, Jeffrey, Purvey, Megan, Roberts, Matthew, Reyaldeen, Reza, Ungerer, Jacobus and Roberts, Jason A. (2019). Pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN). Therapeutic Drug Monitoring, 41 (6), 703-713. doi: 10.1097/ftd.0000000000000658

Pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN)

2019

Journal Article

Pharmacokinetics and pharmacodynamics of anti-infective agents during continuous veno-venous hemofiltration in critically ill patients: lessons learned from an ancillary study of the IVOIRE trial

Breilh, Dominique, Honore, Patrick M., De Bels, David, Roberts, Jason A., Gordien, Jean Baptiste, Fleureau, Catherine, Dewitte, Antoine, Coquin, Julien, Roze, Hadrien, Perez, Paul, Attou, Rachid, Redant, Sebastien, Kugener, Luc, Saux, Marie-Claude, Spapen, Herbert D., Ouattare, Alexandre and Joannes-Boyau, Olivier (2019). Pharmacokinetics and pharmacodynamics of anti-infective agents during continuous veno-venous hemofiltration in critically ill patients: lessons learned from an ancillary study of the IVOIRE trial. Journal of Translational Internal Medicine, 7 (4), 155-169. doi: 10.2478/jtim-2019-0031

Pharmacokinetics and pharmacodynamics of anti-infective agents during continuous veno-venous hemofiltration in critically ill patients: lessons learned from an ancillary study of the IVOIRE trial

2019

Journal Article

Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion

Dhaese, S.A.M., Colin, P., Willems, H., Heffernan, A., Gadeyne, B., Van Vooren, S., Depuydt, P., Hoste, E., Stove, V., Verstraete, A.G., Lipman, J., Roberts, J.A. and De Waele, J.J. (2019). Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion. International Journal of Antimicrobial Agents, 54 (6), 741-749. doi: 10.1016/j.ijantimicag.2019.08.024

Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion

2019

Journal Article

Update in antibiotic therapy in intensive care unit: report from the 2019 Nîmes International Symposium

Leone, Marc, Roberts, Jason A., Bassetti, Matteo, Bouglé, Adrien, Lavigne, Jean-Philippe, Legrand, Matthieu, Neely, Michael, Paiva, José-Artur, Payen, Didier, Rello, Jordi, Roger, Claire, Sjövall, Fredrik and Jung, Boris (2019). Update in antibiotic therapy in intensive care unit: report from the 2019 Nîmes International Symposium. Anaesthesia Critical Care and Pain Medicine, 38 (6), 647-656. doi: 10.1016/j.accpm.2019.09.009

Update in antibiotic therapy in intensive care unit: report from the 2019 Nîmes International Symposium

2019

Journal Article

Linezolid dosing in patients with liver cirrhosis: standard dosing risk toxicity

Luque, Sonia, Muñoz-Bermudez, Rosana, Echeverría-Esnal, Daniel, Sorli, Luisa, Campillo, Nuria, Martínez-Casanova, Javier, González-Colominas, Elena, Álvarez-Lerma, Francisco, Horcajada, Juan Pablo, Grau, Santiago and Roberts, Jason A. (2019). Linezolid dosing in patients with liver cirrhosis: standard dosing risk toxicity. Therapeutic Drug Monitoring, 41 (6), 732-739. doi: 10.1097/FTD.0000000000000665

Linezolid dosing in patients with liver cirrhosis: standard dosing risk toxicity

2019

Journal Article

Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP)

Tabah, Alexis, Bassetti, Matteo, Kollef, Marin H., Zahar, Jean-Ralph, Paiva, José-Artur, Timsit, Jean-Francois, Roberts, Jason A., Schouten, Jeroen, Giamarellou, Helen, Rello, Jordi, De Waele, Jan, Shorr, Andrew F., Leone, Marc, Poulakou, Garyphallia, Depuydt, Pieter and Garnacho-Montero, Jose (2019). Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP). Intensive Care Medicine, 46 (2), 245-265. doi: 10.1007/s00134-019-05866-w

Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP)

2019

Journal Article

Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter?

Abdul-Aziz, Mohd H. and Roberts, Jason A. (2019). Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter?. Current Opinion in Anaesthesiology, 33 (1), 1-82. doi: 10.1097/aco.0000000000000810

Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter?

2019

Journal Article

A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2019). A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study. Analytical and Bioanalytical Chemistry, 411 (29), 7831-7840. doi: 10.1007/s00216-019-02184-4

A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study