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2020

Journal Article

Pharmacodynamic Analysis of Meropenem and Fosfomycin Combination Against Carbapenem-Resistant in Patients with Normal Renal Clearance: Can It Be a Treatment Option?

Mohd Sazlly Lim, Sazlyna, Heffernan, Aaron J., Roberts, Jason A. and Sime, Fekade B. (2020). Pharmacodynamic Analysis of Meropenem and Fosfomycin Combination Against Carbapenem-Resistant in Patients with Normal Renal Clearance: Can It Be a Treatment Option?. Microbial drug resistance (Larchmont, N.Y.), 27 (4) mdr.2020.0197, 546-552. doi: 10.1089/mdr.2020.0197

Pharmacodynamic Analysis of Meropenem and Fosfomycin Combination Against Carbapenem-Resistant in Patients with Normal Renal Clearance: Can It Be a Treatment Option?

2020

Journal Article

Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit

Economou, Caleb J. P., Ordoñez, Jennifer, Wallis, Steven C., Richards, Brent, McWhinney, Brett, Lipman, Jeffrey and Roberts, Jason A. (2020). Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit. International Journal of Antimicrobial Agents, 56 (3) 106058, 1-5. doi: 10.1016/j.ijantimicag.2020.106058

Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit

2020

Journal Article

Effectiveness of therapeutic drug monitoring guided vancomycin dosing in adult patients receiving extra corporeal membrane oxygenation

Marella, Prashanti, Roberts, Jason, Hay, Karen and Shekar, Kiran (2020). Effectiveness of therapeutic drug monitoring guided vancomycin dosing in adult patients receiving extra corporeal membrane oxygenation. Antimicrobial Agents and Chemotherapy, 64 (9) e01179-20. doi: 10.1128/aac.01179-20

Effectiveness of therapeutic drug monitoring guided vancomycin dosing in adult patients receiving extra corporeal membrane oxygenation

2020

Journal Article

Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae

Sumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Islam, Kamrul, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2020). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae. Journal of Antimicrobial Chemotherapy, 75 (9), 2633-2640. doi: 10.1093/jac/dkaa211

Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae

2020

Journal Article

Physician drug prescribing preferences and availability for ventilation of patients with COVID-19

Coombes, Ian D., Dooley, Michael J., Townsend, Shane, Carmichael, Sinead, Poole, Susan G., Karamujic, Nermin, Richards, Brent, Ziegenfuss, Marc, Ankravs, Melissa J., Uren, Hailie, Roberts, Jason A. and Holley, Anthony (2020). Physician drug prescribing preferences and availability for ventilation of patients with COVID-19. Critical Care and Resuscitation, 22 (3), 271-274.

Physician drug prescribing preferences and availability for ventilation of patients with COVID-19

2020

Journal Article

How to design a study to evaluate therapeutic drug monitoring in infectious diseases?

Märtson, A. G., Sturkenboom, M. G. G., Stojanova, J., Cattaneo, D., Hope, W., Marriott, D., Patanwala, A. E., Peloquin, C. A., Wicha, S. G., van der Werf, T. S., Tängdén, T., Roberts, J. A., Neely, M. N. and Alffenaar, J. W. C. (2020). How to design a study to evaluate therapeutic drug monitoring in infectious diseases?. Clinical Microbiology and Infection, 26 (8), 1008-1016. doi: 10.1016/j.cmi.2020.03.008

How to design a study to evaluate therapeutic drug monitoring in infectious diseases?

2020

Journal Article

What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?

Cotta, Menino Osbert, Abdul-Aziz, Mohd Hafiz, Frey, Otto R., Sime, Fekade Bruck, Roberts, Jason A. and Roehr, Anka C. (2020). What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?. Therapeutic Drug Monitoring, 42 (4), 626-630. doi: 10.1097/ftd.0000000000000731

What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?

2020

Journal Article

Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a comprehensive review by the PK/PD of anti-infectives study group of the European Society of Antimicrobial Agents

Zeitlinger, Markus, Koch, Birgit C. P., Bruggemann, Roger, De Cock, Pieter, Felton, Timothy, Hites, Maya, Le, Jennifer, Luque, Sonia, MacGowan, Alasdair P., Marriott, Deborah J. E., Muller, Anouk E., Nadrah, Kristina, Paterson, David L., Standing, Joseph F., Telles, João P., Wölfl-Duchek, Michael, Thy, Michael and Roberts, Jason A. (2020). Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a comprehensive review by the PK/PD of anti-infectives study group of the European Society of Antimicrobial Agents. Clinical Pharmacokinetics, 59 (10), 1195-1216. doi: 10.1007/s40262-020-00924-9

Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a comprehensive review by the PK/PD of anti-infectives study group of the European Society of Antimicrobial Agents

2020

Journal Article

Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models

Dhaese, Sofie, Heffernan, Aaron, Liu, David, Abdul-Aziz, Mohd Hafiz, Stove, Veronique, Tam, Vincent H., Lipman, Jeffrey, Roberts, Jason A. and De Waele, Jan J. (2020). Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models. Clinical Pharmacokinetics, 59 (10), 1237-1250. doi: 10.1007/s40262-020-00919-6

Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models

2020

Journal Article

The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial

Denholm, Justin T., Davis, Joshua, Paterson, David, Roberts, Jason, Morpeth, Susan, Snelling, Thomas, Zentner, Dominica, Rees, Megan, O'Sullivan, Matthew, Price, David, Bowen, Asha, Tong, Steven Y. C., Davis, Joshua, Denholm, Justin, Tong, Steven, ASCOT Investigator Group, Rees, Megan, Paterson, David, Price, David, Morpeth, Susan, O'Sullivan, Matthew, Roberts, Jason, Snelling, Thomas, Anderson, Sue, McQuilton, Zoe, Venkatesh, Bala, Hammond, Naomi, Jha, Vivekanend, Burston, Victoria John ... Slow, Sandy (2020). The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial. Trials, 21 (1) 646. doi: 10.1186/s13063-020-04576-9

The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial

2020

Journal Article

Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model

Heffernan, Aaron J., Sime, Fekade B., Sarovich, Derek S., Neely, Michael, Guerra-Valero, Yarmarly, Naicker, Saiyuri, Cottrell, Kyra, Harris, Patrick, Andrews, Katherine T., Ellwood, David, Wallis, Steven C., Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2020). Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model. Antimicrobial Agents and Chemotherapy, 64 (9) e00879-20. doi: 10.1128/aac.00879-20

Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model

2020

Journal Article

Towards precision medicine: therapeutic drug monitoring-guided dosing of vancomycin and β-lactam antibiotics to maximize effectiveness and minimize toxicity

Cusumano, Jaclyn A., Klinker, Kenneth P., Huttner, Angela, Luther, Megan K., Roberts, Jason A. and LaPlante, Kerry L. (2020). Towards precision medicine: therapeutic drug monitoring-guided dosing of vancomycin and β-lactam antibiotics to maximize effectiveness and minimize toxicity. American Journal of Health-System Pharmacy, 77 (14), 1104-1112. doi: 10.1093/ajhp/zxaa128

Towards precision medicine: therapeutic drug monitoring-guided dosing of vancomycin and β-lactam antibiotics to maximize effectiveness and minimize toxicity

2020

Journal Article

Kidney transplant recipient’s perceptions of blood testing through microsampling and venepuncture

Scuderi, Carla E., Parker, Suzanne L., Jacks, Margaret, John, George, McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Roberts, Jason A., Healy, Helen and Staatz, Christine E. (2020). Kidney transplant recipient’s perceptions of blood testing through microsampling and venepuncture. Bioanalysis, 12 (13) bio-2020-0057, 873-881. doi: 10.4155/bio-2020-0057

Kidney transplant recipient’s perceptions of blood testing through microsampling and venepuncture

2020

Journal Article

What are the current approaches to optimising antimicrobial dosing in the intensive care unit?

Chai, Ming G., Cotta, Menino O., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2020). What are the current approaches to optimising antimicrobial dosing in the intensive care unit?. Pharmaceutics, 12 (7) 638, 1-22. doi: 10.3390/pharmaceutics12070638

What are the current approaches to optimising antimicrobial dosing in the intensive care unit?

2020

Journal Article

Comparative plasma pharmacokinetics of ceftriaxone and ertapenem between normoalbuminemia, hypoalbuminemia and with albumin replacement in a sheep model

Dhanani, Jayesh A., Ahern, Benjamin, Lupinsky, Liad, Jackson, Karen, Wallis, Steven C., Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2020). Comparative plasma pharmacokinetics of ceftriaxone and ertapenem between normoalbuminemia, hypoalbuminemia and with albumin replacement in a sheep model. Antimicrobial Agents and Chemotherapy, 64 (7) e02584-19. doi: 10.1128/aac.02584-19

Comparative plasma pharmacokinetics of ceftriaxone and ertapenem between normoalbuminemia, hypoalbuminemia and with albumin replacement in a sheep model

2020

Journal Article

Non-polymyxin based combinations as potential alternatives in treatment against carbapenem-resistant Acinetobacter baumannii infections

Mohd Sazlly Lim, S., Naicker, S., Ayfan, A. K., Zowawi, H., Roberts, J. A. and Sime, F. B. (2020). Non-polymyxin based combinations as potential alternatives in treatment against carbapenem-resistant Acinetobacter baumannii infections. International Journal of Antimicrobial Agents, 56 (4) 106115, 106115. doi: 10.1016/j.ijantimicag.2020.106115

Non-polymyxin based combinations as potential alternatives in treatment against carbapenem-resistant Acinetobacter baumannii infections

2020

Journal Article

Clinically relevant epithelial lining fluid concentrations of meropenem with ciprofloxacin provide synergistic killing and resistance suppression of hypermutable Pseudomonas aeruginosa in a dynamic biofilm model

Bilal, Hajira, Bergen, Phillip J., Tait, Jessica R., Wallis, Steven C., Peleg, Anton Y., Roberts, Jason A., Oliver, Antonio, Nation, Roger L. and Landersdorfer, Cornelia B. (2020). Clinically relevant epithelial lining fluid concentrations of meropenem with ciprofloxacin provide synergistic killing and resistance suppression of hypermutable Pseudomonas aeruginosa in a dynamic biofilm model. Antimicrobial Agents and Chemotherapy, 64 (7) e00469-20. doi: 10.1128/aac.00469-20

Clinically relevant epithelial lining fluid concentrations of meropenem with ciprofloxacin provide synergistic killing and resistance suppression of hypermutable Pseudomonas aeruginosa in a dynamic biofilm model

2020

Journal Article

Conventional pig as animal model for human renal drug excretion processes: unravelling the porcine renal function by use of a cocktail of exogenous markers

Dhondt, Laura, Croubels, Siska, De Paepe, Peter, Wallis, Steven C., Pandey, Saurabh, Roberts, Jason A., Lipman, Jeffrey, De Cock, Pieter and Devreese, Mathias (2020). Conventional pig as animal model for human renal drug excretion processes: unravelling the porcine renal function by use of a cocktail of exogenous markers. Frontiers in Pharmacology, 11 883, 883. doi: 10.3389/fphar.2020.00883

Conventional pig as animal model for human renal drug excretion processes: unravelling the porcine renal function by use of a cocktail of exogenous markers

2020

Journal Article

Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study

De Bus, Liesbet, Depuydt, Pieter, Steen, Johan, Dhaese, Sofie, De Smet, Ken, Tabah, Alexis, Akova, Murat, Cotta, Menino Osbert, De Pascale, Gennaro, Dimopoulos, George, Fujitani, Shigeki, Garnacho-Montero, Jose, Leone, Marc, Lipman, Jeffrey, Ostermann, Marlies, Paiva, José-Artur, Schouten, Jeroen, Sjövall, Fredrik, Timsit, Jean-François, Roberts, Jason A., Zahar, Jean-Ralph, Zand, Farid, Zirpe, Kapil, De Waele, Jan J. and DIANA study group (2020). Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study. Intensive Care Medicine, 46 (7), 1404-1417. doi: 10.1007/s00134-020-06111-5

Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study

2020

Journal Article

Principles of ethical prescribing for self and others: hydroxychloroquine in the COVID-19 pandemic

Coombes, Ian, Markwell, Alexandra, Kubler, Paul, Redmond, Andrew M., McGurk, Gordon and Roberts, Jason A. (2020). Principles of ethical prescribing for self and others: hydroxychloroquine in the COVID-19 pandemic. Australian Prescriber, 43 (3), 76-77. doi: 10.18773/austprescr.2020.030

Principles of ethical prescribing for self and others: hydroxychloroquine in the COVID-19 pandemic