Skip to menu Skip to content Skip to footer

2019

Journal Article

A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III

Lipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino O., Davis, Joshua S., Finfer, Simon, Glass, Parisa, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Billot, Laurent and Dulhunty, Joel M. (2019). A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III. Critical Care and Resuscitation, 21 (1), 63-68. doi: 10.1016/s1441-2772(23)00582-3

A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III

2019

Journal Article

Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?

Dimopoulos, George, Koulenti, Despoina, Parker, Suzanne L, Roberts, Jason A, Arvaniti, Kostoula and Poulakou, Garyphalia (2019). Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?. Expert Review of Anti-infective Therapy, 17 (3) 14787210.2019.1573669, 201-210. doi: 10.1080/14787210.2019.1573669

Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?

2019

Journal Article

Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients

Cheng, Vesa, Abdul-Aziz, Mohd H., Roberts, Jason A. and Shekar, Kiran (2019). Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients. Expert Opinion on Drug Metabolism & Toxicology, 15 (2), 103-112. doi: 10.1080/17425255.2019.1563596

Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients

2019

Journal Article

A robust statistical approach to analyse population pharmacokinetic data in critically ill patients receiving renal replacement therapy

Paul, Sanjoy Ketan, Roberts, Jason A., Lipman, Jeffrey, Deans, Renae and Samanta, Mayukh (2019). A robust statistical approach to analyse population pharmacokinetic data in critically ill patients receiving renal replacement therapy. Clinical Pharmacokinetics, 58 (2), 263-270. doi: 10.1007/s40262-018-0690-1

A robust statistical approach to analyse population pharmacokinetic data in critically ill patients receiving renal replacement therapy

2019

Journal Article

Antimicrobial dosing in critical care: a pragmatic adult dosing nomogram

Williams, Paul, Beall, Gareth, Cotta, Menino Osbert and Roberts, Jason A. (2019). Antimicrobial dosing in critical care: a pragmatic adult dosing nomogram. International Journal of Antimicrobial Agents, 55 (2) 105837, 105837. doi: 10.1016/j.ijantimicag.2019.10.018

Antimicrobial dosing in critical care: a pragmatic adult dosing nomogram

2019

Journal Article

Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis

Abraham, Jacob, Sinnollareddy, Mahipal G., Roberts, Michael S., Williams, Patricia, Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2019). Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 53 (2), 137-142. doi: 10.1016/j.ijantimicag.2018.09.021

Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis

2019

Journal Article

Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models

Dhaese, Sofie A. M., Farkas, Andras, Colin, Pieter, Lipman, Jeffrey, Stove, Veronique, Verstraete, Alain G., Roberts, Jason A. and De Waele, Jan J. (2019). Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models. Journal of Antimicrobial Chemotherapy, 74 (2), 432-441. doi: 10.1093/jac/dky434

Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models

2019

Journal Article

Solid nanoparticles for oral antimicrobial drug delivery: a review

Raza, Aun, Sime, Fekade Bruck, Cabot, Peter J., Maqbool, Faheem, Roberts, Jason A. and Falconer, James Robert (2019). Solid nanoparticles for oral antimicrobial drug delivery: a review. Drug Discovery Today, 24 (3), 858-866. doi: 10.1016/j.drudis.2019.01.004

Solid nanoparticles for oral antimicrobial drug delivery: a review

2019

Conference Publication

Therapeutic drug monitoring -guided continuous infusion of Piperacillin/Tazobactam significantly improves pharmacokinetic target-attainment in critically ill patients: a retrospective analysis from four years of clinical experience

Richter, D. C., Frey, O., Rohr, A., Roberts, J. A., Koeberer, A., Fuchs, Th, Brenner, T., Lichtenstein, C., Weigand, M. A. and Brinkmann, A. (2019). Therapeutic drug monitoring -guided continuous infusion of Piperacillin/Tazobactam significantly improves pharmacokinetic target-attainment in critically ill patients: a retrospective analysis from four years of clinical experience. 9th International Congress ‘‘Sepsis and Multiorgan Dysfunction’’, Weimar, Germany, 11–13 September 2019. Heidelberg, Germany: Springer.

Therapeutic drug monitoring -guided continuous infusion of Piperacillin/Tazobactam significantly improves pharmacokinetic target-attainment in critically ill patients: a retrospective analysis from four years of clinical experience

2019

Conference Publication

Amikacin loading dose in critically ill patients: development of a non-parametric population pharmacokinetic model

Boidin, C., Bourguignon, L., Cohen, S., Roger, C., Lefrant, J. Y., Roberts, J. A., Allaouchiche, B., Lepape, A., Friggeri, A. and Goutelle, S. (2019). Amikacin loading dose in critically ill patients: development of a non-parametric population pharmacokinetic model. Annual Meeting of French Society of Pharmacology and Therapeutics, and INSERM Clinical Research Centers (CIC) Meeting, Lyon, France, 12–14 June 2019. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Amikacin loading dose in critically ill patients: development of a non-parametric population pharmacokinetic model

2019

Journal Article

Pharmacokinetics/Pharmacodynamics of β-Lactams and therapeutic drug monitoring: from theory to practical issues in the intensive care unit

Williams, Paul, Cotta, Menino Osbert and Roberts, Jason A. (2019). Pharmacokinetics/Pharmacodynamics of β-Lactams and therapeutic drug monitoring: from theory to practical issues in the intensive care unit. Seminars in Respiratory and Critical Care Medicine, 40 (4), 476-487. doi: 10.1055/s-0039-1693498

Pharmacokinetics/Pharmacodynamics of β-Lactams and therapeutic drug monitoring: from theory to practical issues in the intensive care unit

2019

Conference Publication

Amikacin loading dose in critically ill patients: designing optimal dosing regimens based on stochastic control

Boidin, C., Bourguignon, L., Cohen, S., Roger, C., Lefrant, J. Y., Roberts, J. A., Allaouchiche, B., Lepape, A., Friggeri, A. and Goutelle, S. (2019). Amikacin loading dose in critically ill patients: designing optimal dosing regimens based on stochastic control. Annual Meeting of French Society of Pharmacology and Therapeutics, and INSERM Clinical Research Centers (CIC) Meeting, Lyon, France, 12–14 June 2019. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Amikacin loading dose in critically ill patients: designing optimal dosing regimens based on stochastic control

2019

Journal Article

Une voie originale pour une voix originale

Lefrant, Jean-Yves, Lorne, Emmanuel, Asehnoune, Karim, Ausset, Silvain, Beaulieu, Pierre, Biais, Matthieu, Brichant, Jean-Francois, Charbit, Beny, Constantin, Jean-Michel, Cuvillon, Philippe, Dadure, Christophe, Dahmani, Souhayl, David, Jean-Stephane, Fuchs-Buder, Thomas, Geeraerts, Thomas, Godier, Anne, Hanouz, Jean-Luc, Joannes-Boyau, Olivier, Kipnis, Eric, Laudenbach, Vincent, Le Guen, Morgan, Legrand, Matthieu, Lescot, Thomas, Marret, Emmanuel, Mongardon, Nicolas, Ouattara, Alexandre, Pierre, Sebastien, Pirracchio, Romain, Roberts, Jason ... Capdevila, Xavier (2019). Une voie originale pour une voix originale. Anesthesie & Reanimation, 5 (1), 1-3. doi: 10.1016/j.anrea.2018.11.001

Une voie originale pour une voix originale

2019

Journal Article

Diagnostic and medical needs for therapeutic drug monitoring of antibiotics

Mabilat, Claude, Gros, Marie Francoise, Nicolau, David, Mouton, Johan W., Textoris, Julien, Roberts, Jason A., Cotta, Menino O., van Belkum, Alex and Caniaux, Isabelle (2019). Diagnostic and medical needs for therapeutic drug monitoring of antibiotics. European Journal of Clinical Microbiology and Infectious Diseases, 39 (5), 791-797. doi: 10.1007/s10096-019-03769-8

Diagnostic and medical needs for therapeutic drug monitoring of antibiotics

2019

Journal Article

Therapeutic drug monitoring-guided continuous infusion of piperacillin/tazobactam significantly improves pharmacokinetic target attainment in critically ill patients: a retrospective analysis of four years of clinical experience

Richter, Daniel C., Frey, Otto, Röhr, Anka, Roberts, Jason A., Köberer, Andreas, Fuchs, Thomas, Papadimas, Nikolaos, Heinzel-Gutenbrunner, Monika, Brenner, Thorsten, Lichtenstern, Christoph, Weigand, Markus A. and Brinkmann, Alexander (2019). Therapeutic drug monitoring-guided continuous infusion of piperacillin/tazobactam significantly improves pharmacokinetic target attainment in critically ill patients: a retrospective analysis of four years of clinical experience. Infection, 47 (6), 1001-1011. doi: 10.1007/s15010-019-01352-z

Therapeutic drug monitoring-guided continuous infusion of piperacillin/tazobactam significantly improves pharmacokinetic target attainment in critically ill patients: a retrospective analysis of four years of clinical experience

2019

Conference Publication

Optimize cefepime dosing in critically ill patients receiving continuous venovenous hemofiltration

Lin, Hsin, Boidin, Clement, Evans, Danielle, Lopez, Natasha, Healy, Daniel, Serpico, Elena, Goutelle, Sylvain and Roberts, Jason (2019). Optimize cefepime dosing in critically ill patients receiving continuous venovenous hemofiltration. 48th Critical Care Congress of the Society-of-Critical-Care-Medicine, San Diego, CA, United States, 17-20 February 2019. Philadelphia, PA, United States: Lippincott Williams & Wilkins.

Optimize cefepime dosing in critically ill patients receiving continuous venovenous hemofiltration

2019

Conference Publication

Pharmacokinetic dose-approximation significantly increases pharmacokinetic target attainment during the first 24 h of treatment with continuously infused Piperacillin/Tazobactam in critically ill patients

Richter, D. C., Frey, O., Roehr, A., Roberts, J. A., Koeberer, A., Fuchs, Th, Brenner, T., Lichtenstein, C., Weigand, M. A. and Brinkmann, A. (2019). Pharmacokinetic dose-approximation significantly increases pharmacokinetic target attainment during the first 24 h of treatment with continuously infused Piperacillin/Tazobactam in critically ill patients. 9th International Congress ‘‘Sepsis and Multiorgan Dysfunction’’, Weimar, Germany, 11–13 September 2019. Heidelberg, Germany: Springer.

Pharmacokinetic dose-approximation significantly increases pharmacokinetic target attainment during the first 24 h of treatment with continuously infused Piperacillin/Tazobactam in critically ill patients

2019

Book Chapter

Clinical Pharmacy Considerations in ICU

Jamal, Janattul-Ain, Abdul-Aziz, Mohd-Hafiz, Levkovich, Bianca and Roberts, Jason A. (2019). Clinical Pharmacy Considerations in ICU. Encyclopedia of Pharmacy Practice and Clinical Pharmacy. (pp. 849-865) Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-12-812735-3.00576-8

Clinical Pharmacy Considerations in ICU

2018

Journal Article

Cerebrospinal fluid penetration of very high-dose meropenem: a case report

Kerz, Thomas, Von Loewenich, Friederike D., Roberts, Jason, Neulen, Axel and Ringel, Florian (2018). Cerebrospinal fluid penetration of very high-dose meropenem: a case report. Annals of Clinical Microbiology and Antimicrobials, 17 (1) 47, 47. doi: 10.1186/s12941-018-0299-0

Cerebrospinal fluid penetration of very high-dose meropenem: a case report

2018

Journal Article

Understanding the impact of pathophysiological alterations during critical illness on drug pharmacokinetics

Jamal, Janattul-Ain, Roger, Claire and Roberts, Jason A. (2018). Understanding the impact of pathophysiological alterations during critical illness on drug pharmacokinetics. Anaesthesia Critical Care & Pain Medicine, 37 (6), 515-517. doi: 10.1016/j.accpm.2018.10.006

Understanding the impact of pathophysiological alterations during critical illness on drug pharmacokinetics