2019 Journal Article A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING IIILipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino O., Davis, Joshua S., Finfer, Simon, Glass, Parisa, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Billot, Laurent and Dulhunty, Joel M. (2019). A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III. Critical Care and Resuscitation, 21 (1), 63-68. doi: 10.1016/s1441-2772(23)00582-3 |
2019 Journal Article Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?Dimopoulos, George, Koulenti, Despoina, Parker, Suzanne L, Roberts, Jason A, Arvaniti, Kostoula and Poulakou, Garyphalia (2019). Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?. Expert Review of Anti-infective Therapy, 17 (3) 14787210.2019.1573669, 201-210. doi: 10.1080/14787210.2019.1573669 |
2019 Journal Article Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patientsCheng, Vesa, Abdul-Aziz, Mohd H., Roberts, Jason A. and Shekar, Kiran (2019). Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients. Expert Opinion on Drug Metabolism & Toxicology, 15 (2), 103-112. doi: 10.1080/17425255.2019.1563596 |
2019 Journal Article A robust statistical approach to analyse population pharmacokinetic data in critically ill patients receiving renal replacement therapyPaul, Sanjoy Ketan, Roberts, Jason A., Lipman, Jeffrey, Deans, Renae and Samanta, Mayukh (2019). A robust statistical approach to analyse population pharmacokinetic data in critically ill patients receiving renal replacement therapy. Clinical Pharmacokinetics, 58 (2), 263-270. doi: 10.1007/s40262-018-0690-1 |
2019 Journal Article Antimicrobial dosing in critical care: a pragmatic adult dosing nomogramWilliams, Paul, Beall, Gareth, Cotta, Menino Osbert and Roberts, Jason A. (2019). Antimicrobial dosing in critical care: a pragmatic adult dosing nomogram. International Journal of Antimicrobial Agents, 55 (2) 105837, 105837. doi: 10.1016/j.ijantimicag.2019.10.018 |
2019 Journal Article Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsisAbraham, Jacob, Sinnollareddy, Mahipal G., Roberts, Michael S., Williams, Patricia, Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2019). Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 53 (2), 137-142. doi: 10.1016/j.ijantimicag.2018.09.021 |
2019 Journal Article Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic modelsDhaese, Sofie A. M., Farkas, Andras, Colin, Pieter, Lipman, Jeffrey, Stove, Veronique, Verstraete, Alain G., Roberts, Jason A. and De Waele, Jan J. (2019). Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models. Journal of Antimicrobial Chemotherapy, 74 (2), 432-441. doi: 10.1093/jac/dky434 |
2019 Journal Article Solid nanoparticles for oral antimicrobial drug delivery: a reviewRaza, Aun, Sime, Fekade Bruck, Cabot, Peter J., Maqbool, Faheem, Roberts, Jason A. and Falconer, James Robert (2019). Solid nanoparticles for oral antimicrobial drug delivery: a review. Drug Discovery Today, 24 (3), 858-866. doi: 10.1016/j.drudis.2019.01.004 |
2019 Conference Publication Therapeutic drug monitoring -guided continuous infusion of Piperacillin/Tazobactam significantly improves pharmacokinetic target-attainment in critically ill patients: a retrospective analysis from four years of clinical experienceRichter, D. C., Frey, O., Rohr, A., Roberts, J. A., Koeberer, A., Fuchs, Th, Brenner, T., Lichtenstein, C., Weigand, M. A. and Brinkmann, A. (2019). Therapeutic drug monitoring -guided continuous infusion of Piperacillin/Tazobactam significantly improves pharmacokinetic target-attainment in critically ill patients: a retrospective analysis from four years of clinical experience. 9th International Congress ‘‘Sepsis and Multiorgan Dysfunction’’, Weimar, Germany, 11–13 September 2019. Heidelberg, Germany: Springer. |
2019 Conference Publication Amikacin loading dose in critically ill patients: development of a non-parametric population pharmacokinetic modelBoidin, C., Bourguignon, L., Cohen, S., Roger, C., Lefrant, J. Y., Roberts, J. A., Allaouchiche, B., Lepape, A., Friggeri, A. and Goutelle, S. (2019). Amikacin loading dose in critically ill patients: development of a non-parametric population pharmacokinetic model. Annual Meeting of French Society of Pharmacology and Therapeutics, and INSERM Clinical Research Centers (CIC) Meeting, Lyon, France, 12–14 June 2019. Chichester, West Sussex United Kingdom: Wiley-Blackwell. |
2019 Journal Article Pharmacokinetics/Pharmacodynamics of β-Lactams and therapeutic drug monitoring: from theory to practical issues in the intensive care unitWilliams, Paul, Cotta, Menino Osbert and Roberts, Jason A. (2019). Pharmacokinetics/Pharmacodynamics of β-Lactams and therapeutic drug monitoring: from theory to practical issues in the intensive care unit. Seminars in Respiratory and Critical Care Medicine, 40 (4), 476-487. doi: 10.1055/s-0039-1693498 |
2019 Conference Publication Amikacin loading dose in critically ill patients: designing optimal dosing regimens based on stochastic controlBoidin, C., Bourguignon, L., Cohen, S., Roger, C., Lefrant, J. Y., Roberts, J. A., Allaouchiche, B., Lepape, A., Friggeri, A. and Goutelle, S. (2019). Amikacin loading dose in critically ill patients: designing optimal dosing regimens based on stochastic control. Annual Meeting of French Society of Pharmacology and Therapeutics, and INSERM Clinical Research Centers (CIC) Meeting, Lyon, France, 12–14 June 2019. Chichester, West Sussex United Kingdom: Wiley-Blackwell. |
2019 Journal Article Une voie originale pour une voix originaleLefrant, Jean-Yves, Lorne, Emmanuel, Asehnoune, Karim, Ausset, Silvain, Beaulieu, Pierre, Biais, Matthieu, Brichant, Jean-Francois, Charbit, Beny, Constantin, Jean-Michel, Cuvillon, Philippe, Dadure, Christophe, Dahmani, Souhayl, David, Jean-Stephane, Fuchs-Buder, Thomas, Geeraerts, Thomas, Godier, Anne, Hanouz, Jean-Luc, Joannes-Boyau, Olivier, Kipnis, Eric, Laudenbach, Vincent, Le Guen, Morgan, Legrand, Matthieu, Lescot, Thomas, Marret, Emmanuel, Mongardon, Nicolas, Ouattara, Alexandre, Pierre, Sebastien, Pirracchio, Romain, Roberts, Jason ... Capdevila, Xavier (2019). Une voie originale pour une voix originale. Anesthesie & Reanimation, 5 (1), 1-3. doi: 10.1016/j.anrea.2018.11.001 |
2019 Journal Article Diagnostic and medical needs for therapeutic drug monitoring of antibioticsMabilat, Claude, Gros, Marie Francoise, Nicolau, David, Mouton, Johan W., Textoris, Julien, Roberts, Jason A., Cotta, Menino O., van Belkum, Alex and Caniaux, Isabelle (2019). Diagnostic and medical needs for therapeutic drug monitoring of antibiotics. European Journal of Clinical Microbiology and Infectious Diseases, 39 (5), 791-797. doi: 10.1007/s10096-019-03769-8 |
2019 Journal Article Therapeutic drug monitoring-guided continuous infusion of piperacillin/tazobactam significantly improves pharmacokinetic target attainment in critically ill patients: a retrospective analysis of four years of clinical experienceRichter, Daniel C., Frey, Otto, Röhr, Anka, Roberts, Jason A., Köberer, Andreas, Fuchs, Thomas, Papadimas, Nikolaos, Heinzel-Gutenbrunner, Monika, Brenner, Thorsten, Lichtenstern, Christoph, Weigand, Markus A. and Brinkmann, Alexander (2019). Therapeutic drug monitoring-guided continuous infusion of piperacillin/tazobactam significantly improves pharmacokinetic target attainment in critically ill patients: a retrospective analysis of four years of clinical experience. Infection, 47 (6), 1001-1011. doi: 10.1007/s15010-019-01352-z |
2019 Conference Publication Optimize cefepime dosing in critically ill patients receiving continuous venovenous hemofiltrationLin, Hsin, Boidin, Clement, Evans, Danielle, Lopez, Natasha, Healy, Daniel, Serpico, Elena, Goutelle, Sylvain and Roberts, Jason (2019). Optimize cefepime dosing in critically ill patients receiving continuous venovenous hemofiltration. 48th Critical Care Congress of the Society-of-Critical-Care-Medicine, San Diego, CA, United States, 17-20 February 2019. Philadelphia, PA, United States: Lippincott Williams & Wilkins. |
2019 Conference Publication Pharmacokinetic dose-approximation significantly increases pharmacokinetic target attainment during the first 24 h of treatment with continuously infused Piperacillin/Tazobactam in critically ill patientsRichter, D. C., Frey, O., Roehr, A., Roberts, J. A., Koeberer, A., Fuchs, Th, Brenner, T., Lichtenstein, C., Weigand, M. A. and Brinkmann, A. (2019). Pharmacokinetic dose-approximation significantly increases pharmacokinetic target attainment during the first 24 h of treatment with continuously infused Piperacillin/Tazobactam in critically ill patients. 9th International Congress ‘‘Sepsis and Multiorgan Dysfunction’’, Weimar, Germany, 11–13 September 2019. Heidelberg, Germany: Springer. |
2019 Book Chapter Clinical Pharmacy Considerations in ICUJamal, Janattul-Ain, Abdul-Aziz, Mohd-Hafiz, Levkovich, Bianca and Roberts, Jason A. (2019). Clinical Pharmacy Considerations in ICU. Encyclopedia of Pharmacy Practice and Clinical Pharmacy. (pp. 849-865) Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-12-812735-3.00576-8 |
2018 Journal Article Cerebrospinal fluid penetration of very high-dose meropenem: a case reportKerz, Thomas, Von Loewenich, Friederike D., Roberts, Jason, Neulen, Axel and Ringel, Florian (2018). Cerebrospinal fluid penetration of very high-dose meropenem: a case report. Annals of Clinical Microbiology and Antimicrobials, 17 (1) 47, 47. doi: 10.1186/s12941-018-0299-0 |
2018 Journal Article Understanding the impact of pathophysiological alterations during critical illness on drug pharmacokineticsJamal, Janattul-Ain, Roger, Claire and Roberts, Jason A. (2018). Understanding the impact of pathophysiological alterations during critical illness on drug pharmacokinetics. Anaesthesia Critical Care & Pain Medicine, 37 (6), 515-517. doi: 10.1016/j.accpm.2018.10.006 |