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2017

Journal Article

Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model

Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2017). Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model. Antimicrobial Agents and Chemotherapy, 61 (5) e02642, e02642-16. doi: 10.1128/AAC.02642-16

Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model

2017

Journal Article

Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy

Economou, Caleb J. P., Wong, Gloria, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2017). Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy. International Journal of Antimicrobial Agents, 49 (5), 589-594. doi: 10.1016/j.ijantimicag.2017.01.009

Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy

2017

Journal Article

Population pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysis

Konig, Christina, Braune, Stephan, Roberts, Jason A., Nierhaus, Axel, Steinmetz, Oliver M., Baehr, Michael, Frey, Otto R., Langebrake, Claudia and Kluge, Stefan (2017). Population pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysis. Journal of Antimicrobial Chemotherapy, 72 (5), 1433-1440. doi: 10.1093/jac/dkw592

Population pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysis

2017

Journal Article

Nebulization of antiinfective agents in invasively mechanically ventilated adults: a systematic review and meta-analysis

Sole-Lleonart, Candela, Rouby, Jean-Jacques, Blot, Stijn, Poulakou, Garyfallia, Chastre, Jean, Palmer, Lucy B., Bassetti, Matteo, Luyt, Charles-Edouard, Pereira, Jose M., Riera, Jordi, Felton, Tim, Dhanani, Jayesh, Welte, Tobias, Garcia-Alamino, Jose M., Roberts, Jason A. and Rello, Jordi (2017). Nebulization of antiinfective agents in invasively mechanically ventilated adults: a systematic review and meta-analysis. Anesthesiology, 126 (5), 890-908. doi: 10.1097/ALN.0000000000001570

Nebulization of antiinfective agents in invasively mechanically ventilated adults: a systematic review and meta-analysis

2017

Journal Article

The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections

Tangden, T., Ramos Martin, V., Felton, T. W., Nielsen, E. I., Marchand, S., Bruggemann, R. J., Bulitta, J. B., Bassetti, M., Theuretzbacher, U., Tsuji, B. T., Wareham, D. W., Friberg, L. E., de Waele, J. J., Tam, V. H. and Roberts, J. A. (2017). The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections. Intensive Care Medicine, 43 (7), 1021-1032. doi: 10.1007/s00134-017-4780-6

The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections

2017

Journal Article

What’s new in pharmacokinetics of antimicrobials in AKI and RRT?

Roberts, Jason A., Lefrant, Jean-Yves and Lipman, Jeffrey (2017). What’s new in pharmacokinetics of antimicrobials in AKI and RRT?. Intensive Care Medicine, 43 (6), 1-3. doi: 10.1007/s00134-017-4789-x

What’s new in pharmacokinetics of antimicrobials in AKI and RRT?

2017

Journal Article

The use of bloodstream infection mortality to measure the impact of antimicrobial stewardship interventions: assessing the evidence

Coulter, Sonali, Roberts, Jason A., Hajkowicz, Krispin and Halton, Kate (2017). The use of bloodstream infection mortality to measure the impact of antimicrobial stewardship interventions: assessing the evidence. Infectious Disease Reports, 9 (1), 8-12. doi: 10.4081/idr.2017.6849

The use of bloodstream infection mortality to measure the impact of antimicrobial stewardship interventions: assessing the evidence

2017

Journal Article

The effect of pharmacists on ward rounds measured by the STOPP/START tool in a specialized geriatric unit

Mulvogue, K., Roberts, J. A., Coombes, I., Cottrell, N., Kanagarajah, S. and Smith, A. (2017). The effect of pharmacists on ward rounds measured by the STOPP/START tool in a specialized geriatric unit. Journal of Clinical Pharmacy and Therapeutics, 42 (2), 178-184. doi: 10.1111/jcpt.12489

The effect of pharmacists on ward rounds measured by the STOPP/START tool in a specialized geriatric unit

2017

Journal Article

Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial

Udy, Andrew A., Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K. and Lipman, Jeffrey (2017). Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial. International Journal of Antimicrobial Agents, 49 (5), 624-630. doi: 10.1016/j.ijantimicag.2016.12.022

Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial

2017

Journal Article

Population pharmacokinetics of teicoplanin and attainment of pharmacokinetic/pharmacodynamic targets in adult patients with haematological malignancy

Byrne, C. J., Roberts, J. A., McWhinney, B., Ryder, S. A., Fennell, J. P., O'Byrne, P., Deasy, E., Egan, S., Desmond, R., Enright, H., D'Arcy, D. M. and McHugh, J. (2017). Population pharmacokinetics of teicoplanin and attainment of pharmacokinetic/pharmacodynamic targets in adult patients with haematological malignancy. Clinical Microbiology and Infection, 23 (9), 674.e7-674.e13. doi: 10.1016/j.cmi.2017.02.032

Population pharmacokinetics of teicoplanin and attainment of pharmacokinetic/pharmacodynamic targets in adult patients with haematological malignancy

2017

Journal Article

Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Roger, Claire, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2017). Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients. Antimicrobial Agents and Chemotherapy, 61 (3) e01276, e01276-16. doi: 10.1128/AAC.01276-16

Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients

2017

Journal Article

Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review

Paruk, Fathima, Sime, Fekade B., Lipman, Jeffrey and Roberts, Jason A. (2017). Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review. International Journal of Antimicrobial Agents, 49 (4), 395-402. doi: 10.1016/j.ijantimicag.2016.12.014

Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review

2017

Journal Article

Right dose, right now: customized drug dosing in the critically ill

Roberts, Jason A., Kumar, Anand and Lipman, Jeffrey (2017). Right dose, right now: customized drug dosing in the critically ill. Critical Care Medicine, 45 (2), 331-336. doi: 10.1097/CCM.0000000000002210

Right dose, right now: customized drug dosing in the critically ill

2017

Journal Article

Does furosemide increase oxidative stress in acute kidney injury?

Silbert, Benjamin I., Ho, Kwok M., Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2017). Does furosemide increase oxidative stress in acute kidney injury?. Antioxidants & Redox Signaling, 26 (5), 221-226. doi: 10.1089/ars.2016.6845

Does furosemide increase oxidative stress in acute kidney injury?

2017

Book Chapter

Phenoxypenicillins

Geddes, Alasdair M., Gould, Ian M. and Roberts, Jason A. (2017). Phenoxypenicillins. Kucers’ the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 92-99) edited by M. Lindsay Grayson, Sara E. Cosgrove, Suzanne Crowe, William Hope, James S. McCarthy, John Mills, Johan W. Mouton and David L. Paterson. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110

Phenoxypenicillins

2017

Book Chapter

Benzylpenicillin (penicillin G)

Geddes, Alasdair M., Gould, Ian M., Roberts, Jason A., Trubiano, Jason A. and Lindsay Grayson, M. (2017). Benzylpenicillin (penicillin G). Kucers’ the use of antibiotics: a clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 23-91) edited by M. Lindsay Grayson, Sara E. Cosgrove, Suzanne Crowe, William Hope, James S. McCarthy, John Mills, Johan W. Mouton and David L. Paterson. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110

Benzylpenicillin (penicillin G)

2017

Book Chapter

Cephalothin and cefazolin

Denny, Kerina J., Lipman, Jeffrey and Roberts, Jason A. (2017). Cephalothin and cefazolin. Kucers the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 347-360) Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110

Cephalothin and cefazolin

2017

Book

Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically ill

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey eds. (2017). Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically ill. Gateway East, Singapore: Springer Singapore. doi: 10.1007/978-981-10-5336-8

Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically ill

2017

Journal Article

Augmented renal clearance in traumatic brain injury: a single-center observational study of atrial natriuretic peptide, cardiac output, and creatinine clearance

Udy, Andrew A., Jarrett, Paul, Lassig-Smith, Melissa, Stuart, Janine, Starr, Therese, Dunlop, Rachel, Deans, Renae, Roberts, Jason A., Senthuran, Siva, Boots, Robert, Bisht, Kavita, Bulmer, Andrew C. and Lipman, Jeffrey (2017). Augmented renal clearance in traumatic brain injury: a single-center observational study of atrial natriuretic peptide, cardiac output, and creatinine clearance. Journal of Neurotrauma, 34 (1), 137-144. doi: 10.1089/neu.2015.4328

Augmented renal clearance in traumatic brain injury: a single-center observational study of atrial natriuretic peptide, cardiac output, and creatinine clearance

2017

Book Chapter

Pharmacokinetic and pharmacodynamic tools to increase efficacy

Sinnollareddy, Mahipal G., Cotta, Menino O. and Roberts, Jason A. (2017). Pharmacokinetic and pharmacodynamic tools to increase efficacy. Antimicrobial stewardship. (pp. 85-98) edited by Celine Pulcini, Önder Ergönül, Füsun Can and Bojana Beović. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-810477-4.00007-6

Pharmacokinetic and pharmacodynamic tools to increase efficacy