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2016

Journal Article

Impact of 30 mg/kg amikacin and 8 mg/kg gentamicin on serum concentrations in critically ill patients with severe sepsis

Roger, Claire, Nucci, Bastian, Louart, Benjamin, Friggeri, Arnaud, Knani, Haroun, Evrard, Alexandre, Lavigne, Jean-Philippe, Allaouchiche, Bernard, Lefrant, Jean-Yves, Roberts, Jason A. and Muller, Laurent (2016). Impact of 30 mg/kg amikacin and 8 mg/kg gentamicin on serum concentrations in critically ill patients with severe sepsis. Journal of Antimicrobial Chemotherapy, 71 (1), 208-212. doi: 10.1093/jac/dkv291

Impact of 30 mg/kg amikacin and 8 mg/kg gentamicin on serum concentrations in critically ill patients with severe sepsis

2016

Book Chapter

Pharmacokinetic and pharmacodynamic principles of antimicrobials

Osbert Cotta, Menino and Roberts, Jason (2016). Pharmacokinetic and pharmacodynamic principles of antimicrobials. Antimicrobial stewardship. (pp. 71-78) edited by Matthew Laundy, Mark Gilchrist and Laura Whitney. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/med/9780198758792.003.0009

Pharmacokinetic and pharmacodynamic principles of antimicrobials

2016

Book Chapter

Aminoglycoside dosing in obesity

Jamal, Janattul-Ain and Roberts, Jason A. (2016). Aminoglycoside dosing in obesity. Drug Dosing in Obesity: Volume I: Antimicrobials. (pp. 39-44) edited by Syed Tabish R. Zaidi and Jason A. Roberts. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-44034-7_4

Aminoglycoside dosing in obesity

2016

Book Chapter

Isolation and characterization of poliovirus in cell culture systems

Thorley, Bruce R. and Roberts, Jason A. (2016). Isolation and characterization of poliovirus in cell culture systems. Poliovirus: methods and protocols. (pp. 29-53) edited by Javier Martin. New York, United States: Humana Press. doi: 10.1007/978-1-4939-3292-4_4

Isolation and characterization of poliovirus in cell culture systems

2016

Book

Drug dosing in obesity: antimicrobials

Syed Tabish R. Zaidi and Jason A. Roberts eds. (2016). Drug dosing in obesity: antimicrobials. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-44034-7

Drug dosing in obesity: antimicrobials

2016

Journal Article

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Dulhunty, Joel, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Roberts, Jason A., Paul, Sanjoy, Ribas, Antonio Margarit, De Crop, Luc, Spapen, Herbert, Wauters, Joost, Dugernier, Thierry, Jorens, Philippe, Dapper, Ilse, De Backer, Daniel, Taccone, Fabio S., Ruano, Laura, Afonso, Elsa, Alvarez-Lerma, Francisco ... Ozveren, Arife (2016). Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort. Journal of Antimicrobial Chemotherapy, 71 (1), 196-207. doi: 10.1093/jac/dkv288

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort

2015

Journal Article

The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial

Saxena, Manoj K., Taylor, Colman, Billot, Laurent, Bompoint, Severine, Gowardman, John, Roberts, Jason A., Lipman, Jeffery and Myburgh, John (2015). The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial. PloS One, 10 (12) e0144740, e0144740. doi: 10.1371/journal.pone.0144740

The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial

2015

Journal Article

Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models

Shekar, Kiran, Roberts, Jason A., Barnett, Adrian G., Diab, Sara, Wallis, Steven C., Fung, Yoke L. and Fraser, John F. (2015). Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models. Critical Care, 19 (1) 437, 1-11. doi: 10.1186/s13054-015-1151-y

Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models

2015

Journal Article

A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis

Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A.R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K., Lipman, Jeffrey, Bellomo, Rinaldo, Peck, Leah, Young, Helen, Boschert , Catherine, Fletcher, Jason, Smith, Julie, Nand, Kiran, Sara, Treena, Harney, Amy, Rodgers, Helen, Van Haren, Frank, Clarke, Sally, Durham, David, Hannan, Catherine, Matheson, Elisha, Schwartz, Kate ... Paul, Sanjoy (2015). A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis. American Journal of Respiratory and Critical Care Medicine, 192 (11), 1298-1305. doi: 10.1164/rccm.201505-0857OC

A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis

2015

Journal Article

Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos

Cotta, M. O., Roberts, J. A. and Lipman, J. (2015). Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos. Medicina Intensiva (English Edition), 39 (9), 563-572. doi: 10.1016/j.medine.2015.07.001

Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos

2015

Journal Article

Therapeutic drug monitoring of the beta-lactam antibiotics: what is the evidence and which patients should we be using it for?

Huttner, Angela, Harbarth, Stephan, Hope, William W., Lipman, Jeffrey and Roberts, Jason A. (2015). Therapeutic drug monitoring of the beta-lactam antibiotics: what is the evidence and which patients should we be using it for?. Journal of Antimicrobial Chemotherapy, 70 (12), 3178-3183. doi: 10.1093/jac/dkv201

Therapeutic drug monitoring of the beta-lactam antibiotics: what is the evidence and which patients should we be using it for?

2015

Journal Article

The efficacy and safety of adrenergic blockade post burn injury: a systematic review and meta-analysis

Flores, Orlando, Stockton, Kellie, Roberts, Jason A., Muller, Michael J. and Paratz, Jennifer D. (2015). The efficacy and safety of adrenergic blockade post burn injury: a systematic review and meta-analysis. Journal of Trauma and Acute Care Surgery, 80 (1), 146-155. doi: 10.1097/TA.0000000000000887

The efficacy and safety of adrenergic blockade post burn injury: a systematic review and meta-analysis

2015

Journal Article

A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans

Parker, Suzanne L., Lipman, Jeffrey, Dimopoulos, George, Roberts, Jason A. and Wallis, Steven C. (2015). A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 115, 509-514. doi: 10.1016/j.jpba.2015.07.013

A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans

2015

Journal Article

Population pharmacokinetics of fosfomycin in critically ill patients

Parker, Suzanne L., Frantzeskaki, Frantzeska, Wallis, Steven C., Diakaki, Chryssa, Giamarellou, Helen, Koulenti, Despoina, Karaiskos, Ilias, Lipman, Jeffrey, Dimopoulos, George and Roberts, Jason A. (2015). Population pharmacokinetics of fosfomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (10), 6471-6476. doi: 10.1128/AAC.01321-15

Population pharmacokinetics of fosfomycin in critically ill patients

2015

Journal Article

Optimization of dosing regimens and dosing in special populations

Sime, F. B., Roberts, M. S. and Roberts, J. A. (2015). Optimization of dosing regimens and dosing in special populations. Clinical Microbiology and Infection, 21 (10), 886-893. doi: 10.1016/j.cmi.2015.05.002

Optimization of dosing regimens and dosing in special populations

2015

Journal Article

Early detection of preterm intraventricular hemorrhage from clinical electroencephalography

Iyer, Kartik K., Roberts, James A., Hellstrom-Westas, Lena, Wikstrom, Sverre, Hansen Pupp, Ingrid, Ley, David, Breakspear, Michael and Vanhatalo, Sampsa (2015). Early detection of preterm intraventricular hemorrhage from clinical electroencephalography. Critical Care Medicine, 43 (10), 2219-2227. doi: 10.1097/CCM.0000000000001190

Early detection of preterm intraventricular hemorrhage from clinical electroencephalography

2015

Journal Article

Plasma and peritoneal fluid population pharmacokinetics of micafungin in post-surgical patients with severe peritonitis

Grau, S., Luque, S., Campillo, N., Samso, E., Rodriguez, U., Garcia-Bernedo, C.A., Salas, E., Sharma, R., Hope, W.W. and Roberts, J.A. (2015). Plasma and peritoneal fluid population pharmacokinetics of micafungin in post-surgical patients with severe peritonitis. Journal of Antimicrobial Chemotherapy, 70 (10) dkv173, 2854-2861. doi: 10.1093/jac/dkv173

Plasma and peritoneal fluid population pharmacokinetics of micafungin in post-surgical patients with severe peritonitis

2015

Journal Article

Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill

Tsai, Danny, Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill. Current Opinion in Critical Care, 21 (5), 412-420. doi: 10.1097/MCC.0000000000000229

Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill

2015

Journal Article

Augmented renal clearance in critically ill patients: etiology, definition and implications for beta-lactam dose optimization

Sime, Fekade B., Udy, Andrew A. and Roberts, Jason A. (2015). Augmented renal clearance in critically ill patients: etiology, definition and implications for beta-lactam dose optimization. Current Opinion in Pharmacology, 24, 1-6. doi: 10.1016/j.coph.2015.06.002

Augmented renal clearance in critically ill patients: etiology, definition and implications for beta-lactam dose optimization

2015

Journal Article

Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling

Parker, Suzanne L., Roberts, Jason A., Lipman, Jeffrey and Wallis, Steven C. (2015). Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling. Bioanalysis, 7 (19), 2585-2595. doi: 10.4155/bio.15.173

Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling