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2015

Journal Article

Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients

Wong G., Farkas A., Sussman R., Daroczi G., Hope W.W., Lipman J. and Roberts J.A. (2015). Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (3), 1411-1417. doi: 10.1128/AAC.04001-14

Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients

2015

Journal Article

β-Lactam pharmacokinetics during extracorporeal membrane oxygenation therapy: A case-control study

Donadello, Katia, Antonucci, Elio, Cristallini, Stefano, Roberts, Jason A., Beumier, Marjorie, Scolletta, Sabino, Jacobs, Frederique, Rondelet, Benoit, de Backer, Daniel, Vincent, Jean-Louis and Taccone, Fabio Silvio (2015). β-Lactam pharmacokinetics during extracorporeal membrane oxygenation therapy: A case-control study. International Journal of Antimicrobial Agents, 45 (3), 278-282. doi: 10.1016/j.ijantimicag.2014.11.005

β-Lactam pharmacokinetics during extracorporeal membrane oxygenation therapy: A case-control study

2015

Journal Article

Streamlined research funding using short proposals and accelerated peer review: An observational study

Barnett, Adrian G., Herbert, Danielle L., Campbell, Megan, Daly, Naomi, Roberts, Jason A., Mudge, Alison and Graves, Nicholas (2015). Streamlined research funding using short proposals and accelerated peer review: An observational study. BMC Health Services Research, 15 (1) 55. doi: 10.1186/s12913-015-0721-7

Streamlined research funding using short proposals and accelerated peer review: An observational study

2015

Journal Article

A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans

Parker S.L., Lipman J., Roberts J.A. and Wallis S.C. (2015). A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 105, 39-45. doi: 10.1016/j.jpba.2014.11.042

A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans

2015

Journal Article

Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study

Sinnollareddy, Mahipal G., Roberts, Jason A., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Dimopoulos, George (2015). Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study. Critical Care, 19 (33) 33, 1-7. doi: 10.1186/s13054-015-0758-3

Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study

2015

Journal Article

Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Hope, William W. and Roberts, Jason A. (2015). Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development. Seminars in Respiratory and Critical Care Medicine, 36 (1), 136-153. doi: 10.1055/s-0034-1398490

Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development

2015

Journal Article

Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Robertson, Thomas A., Peake, Sandra L. and Roberts, Jason A. (2015). Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. International Journal of Antimicrobial Agents, 45 (2), 192-195. doi: 10.1016/j.ijantimicag.2014.08.013

Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration

2015

Journal Article

Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?

Varghese J.M., Jarrett P., Wallis S.C., Boots R.J., Kirkpatrick C.M.J., Lipman J. and Roberts J.A. (2015). Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?. Journal of Antimicrobial Chemotherapy, 70 (2), 528-533. doi: 10.1093/jac/dku413

Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?

2015

Journal Article

Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement

Kanji S., Hayes M., Ling A., Shamseer L., Chant C., Edwards D.J., Edwards S., Ensom M.H.H., Foster D.R., Hardy B., Kiser T.H., La Porte C., Roberts J.A., Shulman R., Walker S., Zelenitsky S. and Moher D. (2015). Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement. Clinical Pharmacokinetics, 54 (7), 783-795. doi: 10.1007/s40262-015-0236-8

Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement

2015

Journal Article

Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?

Udy, Andrew A., Lipman, Jeffrey, Jarrett, Paul, Klein, Kerenaftali, Wallis, Steven C., Patel, Kashyap, Kirkpatrick, Carl M. J., Kruger, Peter S., Paterson, David L., Roberts, Michael S. and Roberts, Jason A. (2015). Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?. Critical Care, 19 (28) 28, 1-9. doi: 10.1186/s13054-015-0750-y

Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?

2015

Journal Article

Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial

Harris, Patrick N. A., Peleg, Anton Y., Iredell, Jon, Ingram, Paul R., Miyakis, Spiros, Stewardson, Andrew J., Rogers, Benjamin A., McBryde, Emma S., Roberts, Jason A., Lipman, Jeff, Athan, Eugene, Paul, Sanjoy K., Baker, Peter, Harris-Brown, Tiffany and Paterson, David L. (2015). Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial. Trials, 16 (1) 24, 24.1-24.8. doi: 10.1186/s13063-014-0541-9

Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial

2015

Journal Article

Linezolid pharmacokinetics in critically ill patients with renal replacement therapy: Comparison of equi-dose of continuous veno-venous haemofiltration with continuous veno-venous haemodiafiltration

Roger, C., Louart, B., Muller, L., Roberts, J. A. and Lefrant, J. Y. (2015). Linezolid pharmacokinetics in critically ill patients with renal replacement therapy: Comparison of equi-dose of continuous veno-venous haemofiltration with continuous veno-venous haemodiafiltration. Intensive Care Medicine Experimental , 3 A631. doi: 10.1186/2197-425X-3-S1-A631

Linezolid pharmacokinetics in critically ill patients with renal replacement therapy: Comparison of equi-dose of continuous veno-venous haemofiltration with continuous veno-venous haemodiafiltration

2015

Journal Article

Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: A randomised controlled trial of continuous infusion versus intermittent bolus administration

Jamal, Janattul-Ain, Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Udy, Andrew A., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: A randomised controlled trial of continuous infusion versus intermittent bolus administration. International Journal of Antimicrobial Agents, 45 (1), 41-45. doi: 10.1016/j.ijantimicag.2014.09.009

Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: A randomised controlled trial of continuous infusion versus intermittent bolus administration

2015

Journal Article

Subtleties in practical application of prolonged infusion of β-lactam antibiotics

De Waele, J.J., Lipman, J., Carlier, M. and Roberts, J.A. (2015). Subtleties in practical application of prolonged infusion of β-lactam antibiotics. International Journal of Antimicrobial Agents, 45 (5) 4517, 461-463. doi: 10.1016/j.ijantimicag.2015.01.007

Subtleties in practical application of prolonged infusion of β-lactam antibiotics

2015

Journal Article

Anti-infective drugs during continuous hemodialysis - using the bench to learn what to do at the bedside

Roehr, Anka C., Frey, Otto R., Koeberer, Andreas, Fuchs, Thomas, Roberts, Jason A. and Brinkmann, Alexander (2015). Anti-infective drugs during continuous hemodialysis - using the bench to learn what to do at the bedside. International Journal of Artificial Organs, 38 (1), 17-22. doi: 10.5301/ijao.5000377

Anti-infective drugs during continuous hemodialysis - using the bench to learn what to do at the bedside

2015

Journal Article

Impact of an inducement to give high doses of amikacin and gentamicin on serum concentrations in critically ill patients with severe sepsis

Roger, C., Louart, B., Muller, L., Roberts, J. A. and Lefrant, J. Y. (2015). Impact of an inducement to give high doses of amikacin and gentamicin on serum concentrations in critically ill patients with severe sepsis. Intensive Care Medicine Experimental , 3 A402. doi: 10.1186/2197-425X-3-S1-A402

Impact of an inducement to give high doses of amikacin and gentamicin on serum concentrations in critically ill patients with severe sepsis

2015

Conference Publication

The BLISS Study: Beta-Lactam Infusion in Severe Sepsis- Randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting

Abdul-Aziz, M. H., Sulaiman, H., Mat-Nor, M., Rai, V., Wong, K., Hasan, M., Wallis, S., Lipman, J., Staatz, C. E. and Roberts, J. (2015). The BLISS Study: Beta-Lactam Infusion in Severe Sepsis- Randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting. Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), San Diego, CA United States, 17-21 September 2015.

The BLISS Study: Beta-Lactam Infusion in Severe Sepsis- Randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting

2015

Journal Article

Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring

Cotta, Menino Osbert, Gowen, Belinda, Truloff, Natasha, Bursle, Evan, Mcwhinney, Brett, Ungerer, Jacobus P. J., Roberts, Jason A. and Lipman, Jeffrey (2015). Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring. Infectious Diseases, 47 (10), 739-742. doi: 10.3109/23744235.2015.1021831

Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring

2015

Conference Publication

Can therapeutic drug monitoring optimise exposure of piperacillin in febrile neutropenic patients with haematological malignancies? A randomised controlled trial

Sime, F. B., Roberts, M., Tiong, I. S., Gardner, J., Lehman, S., Peake, S., Hahn, U., Warner, M. and Roberts, J. (2015). Can therapeutic drug monitoring optimise exposure of piperacillin in febrile neutropenic patients with haematological malignancies? A randomised controlled trial. 20th Congress of European Hematology Association, Vienna, Austria, 11-14 June 2015. Pavia, Italy: Fondazione Ferrata Storti.

Can therapeutic drug monitoring optimise exposure of piperacillin in febrile neutropenic patients with haematological malignancies? A randomised controlled trial

2015

Journal Article

Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy

Carlier, Mieke, Taccone, Fabio S, Beumier, Majorie, Seyler, Lucie, Cotton, Frederic, Jacobs, Grederique and Roberts, Jason A (2015). Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy. International Journal of Antimicrobial Agents, 46 (4), 413-419. doi: 10.1016/j.ijantimicag.2015.05.020

Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy