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2012

Journal Article

Characterization of poliovirus variants selected for resistance to the antiviral compound V-073

Liu, Hong-Mei, Roberts, Jason A., Moore, Deborah, Anderson, Barbara, Pallansch, Mark A., Pevear, Daniel C., Collett, Marc S. and Oberste, M. Steven (2012). Characterization of poliovirus variants selected for resistance to the antiviral compound V-073. Antimicrobial Agents and Chemotherapy, 56 (11), 5568-5574. doi: 10.1128/AAC.00539-12

Characterization of poliovirus variants selected for resistance to the antiviral compound V-073

2012

Journal Article

Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?

Shekar, Kiran, Roberts, Jason A., Ghassabian, Sussan, Mullany, Daniel V., Wallis, Steven C., Smith, Maree T. and Fraser, John F. (2012). Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?. Journal of Antimicrobial Chemotherapy, 68 (3), 726-727. doi: 10.1093/jac/dks435

Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?

2012

Journal Article

A method for determining the free (unbound) concentration of ten beta-lactam antibiotics in human plasma using high performance liquid chromatography with ultraviolet detection

Briscoe, Scott E., McWhinney, Brett C., Lipman, Jeffrey, Roberts, Jason A. and Ungerer, Jacobus P. J. (2012). A method for determining the free (unbound) concentration of ten beta-lactam antibiotics in human plasma using high performance liquid chromatography with ultraviolet detection. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 907, 178-184. doi: 10.1016/j.jchromb.2012.09.016

A method for determining the free (unbound) concentration of ten beta-lactam antibiotics in human plasma using high performance liquid chromatography with ultraviolet detection

2012

Journal Article

Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation

Shekar, Kiran, Roberts, Jason A., McDonald, Charles I., Fisquet, Stephanie, Barnett, Adrian G., Mullany, Daniel V., Ghassabian, Sussan, Wallis, Steven C., Fung, Yoke L., Smith, Maree T. and Fraser, John F. (2012). Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation. Critical Care, 16 (5) R194, R194.1-R194.7. doi: 10.1186/cc11679

Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation

2012

Journal Article

Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation

Jamal, Janattul-Ain, Economou, Caleb J. P., Lipman, Jeffrey and Roberts, Jason A. (2012). Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation. Current Opinion in Critical Care, 18 (5), 460-471. doi: 10.1097/MCC.0b013e32835685ad

Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation

2012

Journal Article

Investigation of a predicted N-terminal amphipathic α-helix using atomistic molecular dynamics simulation of a complete prototype poliovirus virion

Roberts, Jason A., Kuiper, Michael J., Thorley, Bruce R., Smooker, Peter M. and Hung, Andrew (2012). Investigation of a predicted N-terminal amphipathic α-helix using atomistic molecular dynamics simulation of a complete prototype poliovirus virion. Journal of Molecular Graphics and Modelling, 38, 165-173. doi: 10.1016/j.jmgm.2012.06.009

Investigation of a predicted N-terminal amphipathic α-helix using atomistic molecular dynamics simulation of a complete prototype poliovirus virion

2012

Journal Article

Continuous beta-lactam infusion in critically ill patients: the clinical evidence

Abdul-Aziz, Mohd H., Dulhunty, Joel M., Bellomo, Rinaldo, Lipman, Jeffrey and Roberts, Jason A. (2012). Continuous beta-lactam infusion in critically ill patients: the clinical evidence. Annals of Intensive Care, 2 (1) 37, 37. doi: 10.1186/2110-5820-2-37

Continuous beta-lactam infusion in critically ill patients: the clinical evidence

2012

Journal Article

Pharmacokinetics of intraperitoneal gentamicin in peritoneal dialysis patients with peritonitis (GIPD study)

Varghese, Julie M., Roberts, Jason A., Wallis, Steven C., Boots, Robert J., Healy, Helen, Fassett, Robert G., Lipman, Jeffrey and Ranganathan, Dwarakanathan (2012). Pharmacokinetics of intraperitoneal gentamicin in peritoneal dialysis patients with peritonitis (GIPD study). Clinical Journal of the American Society of Nephrology, 7 (8), 1249-1256. doi: 10.2215/CJN.12211211

Pharmacokinetics of intraperitoneal gentamicin in peritoneal dialysis patients with peritonitis (GIPD study)

2012

Journal Article

Characteristics of bloodstream infections in burn patients: an 11-year retrospective study

Patel, Bhavik M., Paratz, Jennifer D., Mallet, Anthony, Lipman, Jeffrey, Rudd, Michael, Muller, Michael J., Paterson, David L. and Roberts, Jason A. (2012). Characteristics of bloodstream infections in burn patients: an 11-year retrospective study. Burns, 38 (5), 685-690. doi: 10.1016/j.burns.2011.12.018

Characteristics of bloodstream infections in burn patients: an 11-year retrospective study

2012

Journal Article

Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review

Sime, Fekade Bruck, Roberts, Michael S., Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2012). Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review. Annals of Intensive Care, 2 (1) 35, 35.1-35.11. doi: 10.1186/2110-5820-2-35

Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review

2012

Journal Article

DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic

Roberts, Jason, De Waele, Jan J., Dimopoulos, George, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven and Lipman, Jeffrey (2012). DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic. BMC Infectious Diseases, 12 (1) 152, 152.1-152.7. doi: 10.1186/1471-2334-12-152

DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic

2012

Journal Article

A comparison of pulse contour wave analysis and ultrasonic cardiac output monitoring in the critically ill

Udy, A. A., Altukroni, M., Jarrett, P., Roberts, J. A. and Lipman, J. (2012). A comparison of pulse contour wave analysis and ultrasonic cardiac output monitoring in the critically ill. Anaesthesia and Intensive Care, 40 (4), 631-637. doi: 10.1177/0310057X1204000408

A comparison of pulse contour wave analysis and ultrasonic cardiac output monitoring in the critically ill

2012

Journal Article

Subtherapeutic Initial beta-Lactam Concentrations in Select Critically Ill Patients Association Between Augmented Renal Clearance and Low Trough Drug Concentrations

Udy, Andrew A., Varghese, Julie M., Altukroni, Mahdi, Briscoe, Scott, McWhinney, Brett C., Ungerer, Jacobus P., Lipman, Jeffrey and Roberts, Jason A. (2012). Subtherapeutic Initial beta-Lactam Concentrations in Select Critically Ill Patients Association Between Augmented Renal Clearance and Low Trough Drug Concentrations. Chest, 142 (1), 30-39. doi: 10.1378/chest.11-1671

Subtherapeutic Initial beta-Lactam Concentrations in Select Critically Ill Patients Association Between Augmented Renal Clearance and Low Trough Drug Concentrations

2012

Journal Article

Evaluation of medication-related problems in medication reviews: a comparative perspective

Kaur, Sukhpreet, Roberts, Jason A. and Roberts, Michael S. (2012). Evaluation of medication-related problems in medication reviews: a comparative perspective. Annals of Pharmacotherapy, 46 (7-8), 972-982. doi: 10.1345/aph.1Q694

Evaluation of medication-related problems in medication reviews: a comparative perspective

2012

Journal Article

Closing the loop-a colistin clinical study to confirm dosing recommendations from PK/PD modeling

Roberts, Jason A. and Lipman, Jeffrey (2012). Closing the loop-a colistin clinical study to confirm dosing recommendations from PK/PD modeling. Clinical Infectious Diseases, 54 (12), 1727-1729. doi: 10.1093/cid/cis311

Closing the loop-a colistin clinical study to confirm dosing recommendations from PK/PD modeling

2012

Journal Article

beta-Lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: A structured review

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012). beta-Lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: A structured review. Clinical and Experimental Pharmacology and Physiology, 39 (6), 489-496. doi: 10.1111/j.1440-1681.2012.05715.x

beta-Lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: A structured review

2012

Journal Article

Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions

Shekar, Kiran, Fung, Yoke L., Diab, Sara, Mullany, Daniel V., McDonald, Charles I, Dunster, Kimble R., Fisquet, Kimble R, Platts, David G., Stewart, David G, Wallis, Steven C., Smith, Maree T., Roberts, Jason A. and Fraser, John F. (2012). Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions. Critical Care and Resuscitation, 14 (2), 105-111.

Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions

2012

Journal Article

Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions

Shekar, Kiran, Fung, Yoke L., Diab, Sara, Mullany, Daniel V., McDonald, Charles I., Dunster, Kimble R., Fisquet, Stephanie, Platts, David G., Stewart, David, Wallis, Steven C., Smith, Maree T., Roberts, Jason A. and Fraser, John F. (2012). Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions. Critical Care and Resuscitation, 14 (2), 105-111.

Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions

2012

Journal Article

What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance

Udy, Andrew A., Roberts, Jason A., De Waele, Jan J., Paterson, David L. and Lipman, Jeffrey (2012). What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance. International Journal of Antimicrobial Agents, 39 (6), 455-457. doi: 10.1016/j.ijantimicag.2012.02.010

What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance

2012

Journal Article

Antibiotic therapy of pneumonia in critical care

Dhanani, Jayesg, Roberts, Jason A. and Lipman, Jeffrey (2012). Antibiotic therapy of pneumonia in critical care. Current Respiratory Medicine Reviews, 8 (3), 228-238. doi: 10.2174/157339812800493232

Antibiotic therapy of pneumonia in critical care