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2014 Journal Article Comparative α-Helicity of Cyclic Pentapeptides in Waterde Araujo, Aline D., Hoang, Huy N., Kok, W. Mei, Diness, Frederik, Gupta, Praveer, Hill, Timothy A., Driver, Russell W., Price, David A., Liras, Spiros and Fairlie, David P. (2014). Comparative α-Helicity of Cyclic Pentapeptides in Water. Angewandte Chemie International Edition, 53 (27), 6965-6969. doi: 10.1002/anie.201310245/abstract |
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2014 Journal Article Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal painDantas De Araujo, Aline, Mobli, Mehdi, Castro, Joel, Harrington, Andrea M., Vetter, Irina, Dekan, Zoltan, Muttenthale, Markus, Wan, JingJing, Lewis, Richard J., King, Glenn F., Brierley, Stuart M. and Alewood, Paul F. (2014). Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain. Nature Communications, 5 (1) 3165, 3165.1-3165.12. doi: 10.1038/ncomms4165 |
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2021 Journal Article Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-MycMadden, Sarah K., de Araujo, Aline Dantas, Gerhardt, Mara, Fairlie, David P. and Mason, Jody M. (2021). Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc. Molecular Cancer, 20 (1) 3, 3. doi: 10.1186/s12943-020-01291-6 |
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2019 Journal Article A novel long-range n to π* interaction secures the smallest known α-helix in waterHoang, Huy N., Wu, Chongyang, Hill, Timothy A., Dantas de Araujo, Aline, Bernhardt, Paul V., Liu, Ligong and Fairlie, David P. (2019). A novel long-range n to π* interaction secures the smallest known α-helix in water. Angewandte Chemie International Edition, 58 (52) ange.201911277, 18873-18877. doi: 10.1002/anie.201911277 |
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2018 Journal Article Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal PeptidesHerzig, Volker, de Araujo, Aline, Greenwood, Kathryn, Chin, Yanni, Windley, Monique, Chong, Youmie, Muttenthaler, Markus, Mobli, Mehdi, Audsley, Neil, Nicholson, Graham, Alewood, Paul and King, Glenn (2018). Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides. Biomedicines, 6 (3) 90, 90. doi: 10.3390/biomedicines6030090 |
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2018 Journal Article Bicyclic helical peptides as dual inhibitors selective for Bcl2A1 and Mcl-1 proteinsde Araujo, Aline D., Lim, Junxian, Wu, Kai-Chen, Xiang, Yibin, Good, Andrew C., Skerlj, Renato and Fairlie, David P. (2018). Bicyclic helical peptides as dual inhibitors selective for Bcl2A1 and Mcl-1 proteins. Journal of Medicinal Chemistry, 61 (7), 2962-2972. doi: 10.1021/acs.jmedchem.8b00010 |
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2018 Journal Article Chemically Diverse Helix-Constrained Peptides Using Selenocysteine CrosslinkingDantas de Araujo, Aline, Perry, Samuel R. and Fairlie, David P. (2018). Chemically Diverse Helix-Constrained Peptides Using Selenocysteine Crosslinking. Organic Letters, 20 (5), 1453-1456. doi: 10.1021/acs.orglett.8b00233 |
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2018 Journal Article Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeabilityPerry, Samuel R., Hill, Timothy A., de Araujo, Aline D., Hoang, Huy N. and Fairlie, David P. (2018). Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability. Organic & Biomolecular Chemistry, 16 (3), 367-371. doi: 10.1039/c7ob02952g |
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2017 Journal Article Europium-labeled synthetic C3a protein as a novel fluorescent probe for human complement C3a receptorDantas de Araujo, Aline, Wu, Chongyang, Wu, Kai-Chen, Reid, Robert C., Durek, Thomas, Lim, Junxian and Fairlie, David P. (2017). Europium-labeled synthetic C3a protein as a novel fluorescent probe for human complement C3a receptor. Bioconjugate Chemistry, 28 (6), 1669-1676. doi: 10.1021/acs.bioconjchem.7b00132 |
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2017 Journal Article Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signalingPlisson, Fabien, Hill, Timothy A., Mitchell, Justin M., Hoang, Huy N., de Araujo, Aline D., Xu, Weijun, Cotterell, Adam, Edmonds, David J., Stanton, Robert V., Derksen, David R., Loria, Paula M., Griffith, David A., Price, David A., Liras, Spiros and Fairlie, David P. (2017). Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling. European Journal of Medicinal Chemistry, 127, 703-714. doi: 10.1016/j.ejmech.2016.10.044 |
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2017 Journal Article Electrophilic helical peptides that bond covalently, irreversibly, and selectively in a protein-protein interaction siteDantas De Araujo, Aline, Lim, Junxian, Good, Andrew C., Skerlj, Renato T. and Fairlie, David P. (2017). Electrophilic helical peptides that bond covalently, irreversibly, and selectively in a protein-protein interaction site. ACS Medicinal Chemistry Letters, 8 (1), 22-26. doi: 10.1021/acsmedchemlett.6b00395 |
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2016 Journal Article Review stapling peptides using cysteine crosslinkingFairlie, David P. and Dantas de Araujo, Aline (2016). Review stapling peptides using cysteine crosslinking. Biopolymers, 106 (6), 843-852. doi: 10.1002/bip.22877 |
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2016 Journal Article Helix nucleation by the smallest known α-helix in waterHoang, Huy N., Driver, Russell W., Beyer, Renee L., Hill, Timothy A., de Araujo, Aline D., Plisson, Fabien, Harrison, Rosemary S., Goedecke, Lena, Shepherd, Nicholas E. and Fairlie, David P. (2016). Helix nucleation by the smallest known α-helix in water. Angewandte Chemie (International Edition), 55 (29), 8275-8279. doi: 10.1002/anie.201602079 |
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2016 Journal Article Development of cell-penetrating peptide-based drug leads to inhibit MDMX:p53 and MDM2:p53 interactionsPhilippe, Gregoire, Huang, Yen-Hua, Cheneval, Olivier, Lawrence, Nicole, Zhang, Zhen, Fairlie, David P., Craik, David J., Dantas De Araujo, Aline and Troeira Henriques, Sonia (2016). Development of cell-penetrating peptide-based drug leads to inhibit MDMX:p53 and MDM2:p53 interactions. Biopolymers - Peptide Science, 106 (6), 853-863. doi: 10.1002/bip.22893 |
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2013 Journal Article Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?Dantas De Araujo, Aline, Herzig, Volker, Windley, Monique J., Dziemborowicz, Slawomir, Mobli, Mehdi, Nicholson, Graham M., Alewood, Paul F. and King, Glenn F. (2013). Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?. Antioxidants and Redox Signaling, 19 (16), 1976-1980. doi: 10.1089/ars.2013.5365 |
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2012 Journal Article Cyclization of peptides by using selenolanthionine bridgesDantas de Araujo, Aline, Mobli, Mehdi, King, Glenn F. and Alewood, Paul F. (2012). Cyclization of peptides by using selenolanthionine bridges. Angewandte Chemie International Edition, 51 (41), 10298-10302. doi: 10.1002/anie.201204229 |
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2011 Journal Article Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffoldsDantas de Araujo, Aline, Christensen, Caspar, Buchardt, Jens, Kent, Stephen B. H. and Alewood, Paul F. (2011). Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffolds. Chemistry: A European Journal, 17 (50), 13983-13986. doi: 10.1002/chem.201102732 |
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2011 Journal Article Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted foldingDantas de Araujo, Aline, Callaghan, Brid, Nevin, Simon T., Daly, Norelle L., Craik, David J., Moretta, Melissa, Hopping, Gene, Christie, Macdonald J., Adams, David J. and Alewood, Paul F. (2011). Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Edition), 50 (29), 6527-6529. doi: 10.1002/anie.201101642 |
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2010 Journal Article Modulating oxytocin activity and plasma stability by disulfide bond engineeringMuttenthaler, Markus, Andersson, Asa, Dantas de Araujo, Aline, Dekan, Zoltan, Lewis, Richard J. and Alewood, Paul F. (2010). Modulating oxytocin activity and plasma stability by disulfide bond engineering. Journal of Medicinal Chemistry, 53 (24), 8585-8596. doi: 10.1021/jm100989w |
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2010 Conference Publication Understanding the role of the unusual constrained eight-membered disulfide ring of spider toxinsDantas de Araujo, A. D., Herzig, V., Mobli, M., Windley, M. J., Nicholson, G. M., Alewood, P. F. and King, G. F. (2010). Understanding the role of the unusual constrained eight-membered disulfide ring of spider toxins. 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.1303 |
