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2016

Journal Article

Development of cell-penetrating peptide-based drug leads to inhibit MDMX:p53 and MDM2:p53 interactions

Philippe, Gregoire, Huang, Yen-Hua, Cheneval, Olivier, Lawrence, Nicole, Zhang, Zhen, Fairlie, David P., Craik, David J., Dantas De Araujo, Aline and Troeira Henriques, Sonia (2016). Development of cell-penetrating peptide-based drug leads to inhibit MDMX:p53 and MDM2:p53 interactions. Biopolymers - Peptide Science, 106 (6), 853-863. doi: 10.1002/bip.22893

Development of cell-penetrating peptide-based drug leads to inhibit MDMX:p53 and MDM2:p53 interactions

2013

Journal Article

Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?

Dantas De Araujo, Aline, Herzig, Volker, Windley, Monique J., Dziemborowicz, Slawomir, Mobli, Mehdi, Nicholson, Graham M., Alewood, Paul F. and King, Glenn F. (2013). Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?. Antioxidants and Redox Signaling, 19 (16), 1976-1980. doi: 10.1089/ars.2013.5365

Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?

2012

Journal Article

Cyclization of peptides by using selenolanthionine bridges

Dantas de Araujo, Aline, Mobli, Mehdi, King, Glenn F. and Alewood, Paul F. (2012). Cyclization of peptides by using selenolanthionine bridges. Angewandte Chemie International Edition, 51 (41), 10298-10302. doi: 10.1002/anie.201204229

Cyclization of peptides by using selenolanthionine bridges

2011

Journal Article

Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffolds

Dantas de Araujo, Aline, Christensen, Caspar, Buchardt, Jens, Kent, Stephen B. H. and Alewood, Paul F. (2011). Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffolds. Chemistry: A European Journal, 17 (50), 13983-13986. doi: 10.1002/chem.201102732

Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffolds

2011

Journal Article

Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding

Dantas de Araujo, Aline, Callaghan, Brid, Nevin, Simon T., Daly, Norelle L., Craik, David J., Moretta, Melissa, Hopping, Gene, Christie, Macdonald J., Adams, David J. and Alewood, Paul F. (2011). Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Edition), 50 (29), 6527-6529. doi: 10.1002/anie.201101642

Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding

2010

Journal Article

Modulating oxytocin activity and plasma stability by disulfide bond engineering

Muttenthaler, Markus, Andersson, Asa, Dantas de Araujo, Aline, Dekan, Zoltan, Lewis, Richard J. and Alewood, Paul F. (2010). Modulating oxytocin activity and plasma stability by disulfide bond engineering. Journal of Medicinal Chemistry, 53 (24), 8585-8596. doi: 10.1021/jm100989w

Modulating oxytocin activity and plasma stability by disulfide bond engineering

2010

Conference Publication

Oxytocin agonist design - A selenocysteine mimetic reveals a functional selectivity switch for the human oxytocin receptor

Muttenthaler, M. M., de Araujo, A. D., Andersson, A., Vetter, I., Gruber, C., Ramos, Y. Garcia, Feytens, D., Bergmayr, C., Freissmuth, M., Lewis, R. and Alewood, P. (2010). Oxytocin agonist design - A selenocysteine mimetic reveals a functional selectivity switch for the human oxytocin receptor. 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. Chichester, West Sussex, U.K.: John Wiley & Sons. doi: 10.1002/psc.1303

Oxytocin agonist design - A selenocysteine mimetic reveals a functional selectivity switch for the human oxytocin receptor

2010

Conference Publication

Understanding the role of the unusual constrained eight-membered disulfide ring of spider toxins

Dantas de Araujo, A. D., Herzig, V., Mobli, M., Windley, M. J., Nicholson, G. M., Alewood, P. F. and King, G. F. (2010). Understanding the role of the unusual constrained eight-membered disulfide ring of spider toxins. 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.1303

Understanding the role of the unusual constrained eight-membered disulfide ring of spider toxins

2010

Journal Article

p-Nitrobenzyl protection for cysteine and selenocysteine: A more stable alternative to the acetamidomethyl group

Muttenthaler, Markus, Ramos, Yesica Garcia, Feytens, Debby, Dantas de Araujo, Aline and Alewood, Paul F. (2010). p-Nitrobenzyl protection for cysteine and selenocysteine: A more stable alternative to the acetamidomethyl group. Biopolymers, 94 (4), 423-432. doi: 10.1002/bip.21502

p-Nitrobenzyl protection for cysteine and selenocysteine: A more stable alternative to the acetamidomethyl group

2009

Journal Article

Direct Visualization of Disulfide Bonds through Diselenide Proxies Using Se-77 NMR Spectroscopy

Mobli, M., Dantas de Araujo, A., Lambert, L. K., Pierens, G. K., Windley, M. J., Nicholson, G. M., Alewood, P. F. and King, G. E. (2009). Direct Visualization of Disulfide Bonds through Diselenide Proxies Using Se-77 NMR Spectroscopy. Angewandte Chemie International Edition, 48 (49), 9312-9314. doi: 10.1002/anie.200905206

Direct Visualization of Disulfide Bonds through Diselenide Proxies Using Se-77 NMR Spectroscopy

2008

Conference Publication

Unequivocal direct determination of the disulfide bond connectivities in proteins using 77Se NMR

Mobli, M., Lambert, L. K., Pierens, G. K., Dantas de Araujo, A., Alewood, P. F. and King, G. F. (2008). Unequivocal direct determination of the disulfide bond connectivities in proteins using 77Se NMR. 7th Biennial Conference of the Australian and New Zealand Society for Magnetic Resonance (ANZMAG 2008), Couran Cove, Australia, 7-11 December 2008.

Unequivocal direct determination of the disulfide bond connectivities in proteins using 77Se NMR

2006

Journal Article

Diels-Alder ligation of peptides and proteins

Dantas de Araújo, Aline, Palomo, Jose M., Cramer, Janina, Seitz, Oliver, Alexandrov, Kirill and Waldmann, Herbert (2006). Diels-Alder ligation of peptides and proteins. Chemistry: A European Journal, 12 (23), 6095-6109. doi: 10.1002/chem.200600148

Diels-Alder ligation of peptides and proteins

2006

Conference Publication

Synthesis of lanthionine analogs of conotoxins

de Araujo, A. D. and Alewood, P. F. (2006). Synthesis of lanthionine analogs of conotoxins. CHICHESTER: JOHN WILEY & SONS LTD.

Synthesis of lanthionine analogs of conotoxins

2005

Journal Article

Diels-alder ligation and surface immobilization of proteins

Dantas de Araújo, Aline, Palomo, Jose M., Cramer, Janina, Köhn, Maja, Schröder, Hendrik, Wacker, Ron, Niemeyer, Christof, Alexandrov, Kirill and Waldmann, Herbert (2005). Diels-alder ligation and surface immobilization of proteins. Angewandte Chemie, 118 (2), 302-307. doi: 10.1002/ange.200502266

Diels-alder ligation and surface immobilization of proteins

2005

Journal Article

Diels-alder ligation and surface immobilization of proteins

Dantas de Araujo, Aline, Palomo, Jose M., Cramer, Janina, Kohn, Maja, Schroder, Hendrik, Wacker, Ron, Niemeyer, Christof, Alexandrov, Kirill and Waldmann, Herbert (2005). Diels-alder ligation and surface immobilization of proteins. Angewandte Chemie International Edition, 45 (2), 296-301. doi: 10.1002/anie.200502266

Diels-alder ligation and surface immobilization of proteins

1999

Journal Article

A mild method for the preparation of 8-substituted xanthines from 5,6-diaminouracils

de Araujo, AD, Bacher, E, Demnitz, FWJ and Santos, DA (1999). A mild method for the preparation of 8-substituted xanthines from 5,6-diaminouracils. Heterocycles, 51 (1), 29-36.

A mild method for the preparation of 8-substituted xanthines from 5,6-diaminouracils