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2019 Journal Article Development of high-throughput fluorescent-based screens to accelerate discovery of P2X inhibitors from animal venomsBibic, Lucka, Herzig, Volker, King, Glenn F. and Stokes, Leanne (2019). Development of high-throughput fluorescent-based screens to accelerate discovery of P2X inhibitors from animal venoms. Journal of Natural Products, 82 (9) acs.jnatprod.9b00410, 2559-2567. doi: 10.1021/acs.jnatprod.9b00410 |
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2019 Journal Article A cell-penetrating scorpion toxin enables mode-specific modulation of TRPA1 and painLin King, John V., Emrick, Joshua J., Kelly, Mark J. S., Herzig, Volker, King, Glenn F., Medzihradszky, Katalin F. and Julius, David (2019). A cell-penetrating scorpion toxin enables mode-specific modulation of TRPA1 and pain. Cell, 178 (6), 1362-1374.e16. doi: 10.1016/j.cell.2019.07.014 |
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2019 Journal Article Tying pest insects in knots: the deployment of spider‐venom‐derived knottins as bioinsecticidesKing, Glenn F. (2019). Tying pest insects in knots: the deployment of spider‐venom‐derived knottins as bioinsecticides. Pest Management Science, 75 (9) ps.5452, 2437-2445. doi: 10.1002/ps.5452 |
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2019 Journal Article Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureusMonk, Ian R., Shaikh, Nausad, Begg, Stephanie L., Gajdiss, Mike, Sharkey, Liam K. R., Lee, Jean Y. H., Pidot, Sacha J., Seemann, Torsten, Kuiper, Michael, Winnen, Brit, Hvorup, Rikki, Collins, Brett M., Bierbaum, Gabriele, Udagedara, Saumya R., Morey, Jacqueline R., Pulyani, Neha, Howden, Benjamin P., Maher, Megan J., McDevitt, Christopher A., King, Glenn F. and Stinear, Timothy P. (2019). Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus. Nature Communications, 10 (1) 3067, 3067. doi: 10.1038/s41467-019-10932-4 |
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2019 Journal Article Sea anemone toxins: a structural overviewMadio, Bruno, King, Glenn F. and Undheim, Eivind A. B. (2019). Sea anemone toxins: a structural overview. Marine Drugs, 17 (6) 325, 325. doi: 10.3390/md17060325 |
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2019 Journal Article The antitrypanosomal diarylamidines, diminazene and pentamidine, show anthelmintic activity against Haemonchus contortus in vitroNixon, Samantha A., Saez, Natalie J., Herzig, Volker, King, Glenn F. and Kotze, Andrew C. (2019). The antitrypanosomal diarylamidines, diminazene and pentamidine, show anthelmintic activity against Haemonchus contortus in vitro. Veterinary Parasitology, 270, 40-46. doi: 10.1016/j.vetpar.2019.05.008 |
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2019 Journal Article Periplasmic expression of 4/7 alpha-conotoxin TxIA analogs in E. coli favors ribbon isomer formation suggestion of a binding mode at the α7 nAChREl Hamdaoui, Yamina, Wu, Xiaosa, Clark, Richard J., Giribaldi, Julien, Anangi, Raveendra, Craik, David J., King, Glenn F., Dutertre, Sebastien, Kaas, Quentin, Herzig, Volker and Nicke, Annette (2019). Periplasmic expression of 4/7 alpha-conotoxin TxIA analogs in E. coli favors ribbon isomer formation suggestion of a binding mode at the α7 nAChR. Frontiers in Pharmacology, 10 (MAY) 577, 577. doi: 10.3389/fphar.2019.00577 |
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2019 Journal Article The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype- and species-dependent: importance of interactions at the channel subunit interface and potential for engineering selective analoguesCristofori-Armstrong, Ben, Saez, Natalie J., Chassagnon, Irène R., King, Glenn F. and Rash, Lachlan D. (2019). The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype- and species-dependent: importance of interactions at the channel subunit interface and potential for engineering selective analogues. Biochemical Pharmacology, 163, 381-390. doi: 10.1016/j.bcp.2019.03.004 |
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2019 Journal Article NMR structure and dynamics of inhibitory repeat domain variant 12, a plant protease inhibitor from Capsicum annuum, and its structural relationship to other plant protease inhibitorsGartia, Janeka, Anangi, Raveendra, Joshi, Rakesh S., Giri, Ashok P., King, Glenn F., Barnwal, Ravi P. and Chary, Kandala V. R. (2019). NMR structure and dynamics of inhibitory repeat domain variant 12, a plant protease inhibitor from Capsicum annuum, and its structural relationship to other plant protease inhibitors. Journal of Biomolecular Structure and Dynamics, 38 (5), 1-10. doi: 10.1080/07391102.2019.1607559 |
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2019 Journal Article A process of convergent amplification and tissue‐specific expression dominate the evolution of toxin and toxin‐like genes in sea anemonesSurm, Joachim M., Smith, Hayden L., Madio, Bruno, Undheim, Eivind A. B., King, Glenn F., Hamilton, Brett R., van der Burg, Chloé A., Pavasovic, Ana and Prentis, Peter J. (2019). A process of convergent amplification and tissue‐specific expression dominate the evolution of toxin and toxin‐like genes in sea anemones. Molecular Ecology, 28 (9) mec.15084, 2272-2289. doi: 10.1111/mec.15084 |
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2019 Journal Article Can we resolve the taxonomic bias in spider venom research?Herzig, Volker, King, Glenn F. and Undheim, Eivind A.B. (2019). Can we resolve the taxonomic bias in spider venom research?. Toxicon: X, 1 100005, 100005. doi: 10.1016/j.toxcx.2018.100005 |
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2018 Journal Article Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug targetMa, Linlin, Chin, Yanni K.Y., Dekan, Zoltan, Herzig, Volker, Chow, Chun Yuen, Heighway, Jacqueline, Lam, Sau Wing, Guillemin, Gilles J., Alewood, Paul F. and King, Glenn F. (2018). Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target. Biochemical Pharmacology, 158, 60-72. doi: 10.1016/j.bcp.2018.08.038 |
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2018 Journal Article Buzz kill: Function and proteomic composition of venom from the Giant Assassin Fly Dolopus genitalis (Diptera: Asilidae)Walker, Andrew, Dobson, James, Jin, Jiayi, Robinson, Samuel, Herzig, Volker, Vetter, Irina, King, Glenn and Fry, Bryan (2018). Buzz kill: Function and proteomic composition of venom from the Giant Assassin Fly Dolopus genitalis (Diptera: Asilidae). Toxins, 10 (11) 456, 456. doi: 10.3390/toxins10110456 |
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2018 Journal Article Efficient enzymatic ligation of inhibitor cystine knot spider venom peptides: using sortase a to form double-knottins that probe voltage-gated sodium channel NaV1.7Agwa, Akello J., Blomster, Linda V., Craik, David J., King, Glenn F. and Schroeder, Christina I. (2018). Efficient enzymatic ligation of inhibitor cystine knot spider venom peptides: using sortase a to form double-knottins that probe voltage-gated sodium channel NaV1.7. Bioconjugate Chemistry, 29 (10) acs.bioconjchem.8b00505, 3309-3319. doi: 10.1021/acs.bioconjchem.8b00505 |
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2018 Journal Article Entomo-venomics: the evolution, biology and biochemistry of insect venomsWalker, Andrew A., Robinson, Samuel D., Yeates, David K., Jin, Jiayi, Baumann, Kate, Dobson, James, Fry, Bryan G. and King, Glenn F. (2018). Entomo-venomics: the evolution, biology and biochemistry of insect venoms. Toxicon: official journal of the International Society on Toxinology, 154, 15-27. doi: 10.1016/j.toxicon.2018.09.004 |
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2018 Journal Article 1H, 13C and 15N NMR assignments of two plant protease inhibitors (IRD7 and IRD12) from the plant Capsicum annuumGartia, Janeka, Barnwal, Ravi Pratap, Anangi, Raveendra, Giri, Ashok R., King, Glenn and Chary, Kandala V. R. (2018). 1H, 13C and 15N NMR assignments of two plant protease inhibitors (IRD7 and IRD12) from the plant Capsicum annuum. Biomolecular NMR Assignments, 13 (1), 31-35. doi: 10.1007/s12104-018-9846-z |
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2018 Journal Article A comprehensive portrait of the venom of the giant red bull ant, Myrmecia gulosa, reveals a hyperdiverse hymenopteran toxin gene familyRobinson, Samuel D., Mueller, Alexander, Clayton, Daniel, Starobova, Hana, Hamilton, Brett R., Payne, Richard J., Vetter, Irina, King, Glenn F. and Undheim, Eivind A. B. (2018). A comprehensive portrait of the venom of the giant red bull ant, Myrmecia gulosa, reveals a hyperdiverse hymenopteran toxin gene family. Science Advances, 4 (9) eaau4640, eaau4640. doi: 10.1126/sciadv.aau4640 |
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2018 Journal Article Venoms to the rescueHolford, Mande, Daly, Marymegan, King, Glenn F. and Norton, Raymond S. (2018). Venoms to the rescue. Science, 361 (6405), 842-844. doi: 10.1126/science.aau7761 |
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2018 Journal Article Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal PeptidesHerzig, Volker, de Araujo, Aline, Greenwood, Kathryn, Chin, Yanni, Windley, Monique, Chong, Youmie, Muttenthaler, Markus, Mobli, Mehdi, Audsley, Neil, Nicholson, Graham, Alewood, Paul and King, Glenn (2018). Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides. Biomedicines, 6 (3) 90, 90. doi: 10.3390/biomedicines6030090 |
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2018 Journal Article PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide foldMadio, Bruno, Peigneur, Steve, Chin, Yanni K. Y., Hamilton, Brett R., Henriques, Sónia Troeira, Smith, Jennifer J., Cristofori-Armstrong, Ben, Dekan, Zoltan, Boughton, Berin A., Alewood, Paul F., Tytgat, Jan, King, Glenn F. and Undheim, Eivind A. B. (2018). PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold. Cellular and Molecular Life Sciences, 75 (24), 4511-4524. doi: 10.1007/s00018-018-2897-6 |
