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2018 Journal Article Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature deathRichards, Kay L., Milligan, Carol J., Richardson, Robert J., Jancovski, Nikola, Grunnet, Morten, Jacobson, Laura H., Undheim, Eivind A. B., Mobli, Mehdi, Chow, Chun Yuen, Herzig, Volker, Csoti, Agota, Panyi, Gyorgy, Reid, Christopher A., King, Glenn F. and Petrou, Steven (2018). Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death. Proceedings of the National Academy of Sciences, 115 (34), 201804764-E8085. doi: 10.1073/pnas.1804764115 |
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2018 Journal Article Dipteran toxicity assays for determining the oral insecticidal activity of venoms and toxinsGuo, Shaodong, Herzig, Volker and King, Glenn F. (2018). Dipteran toxicity assays for determining the oral insecticidal activity of venoms and toxins. Toxicon, 150, 297-303. doi: 10.1016/j.toxicon.2018.06.077 |
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2018 Journal Article Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferationIkonomopoulou, Maria P., Fernandez-Rojo, Manuel A., Pineda, Sandy S., Cabezas-Sainz, Pablo, Winnen, Brit, Morales, Rodrigo A. V., Brust, Andreas, Sanchez, Laura, Alewood, Paul F., Ramm, Grant A., Miles, John J. and King, Glenn F. (2018). Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation. Scientific Reports, 8 (1) 11519, 11519. doi: 10.1038/s41598-018-29826-4 |
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2018 Journal Article Structural basis for the modulation of voltage-gated sodium channels by animal toxinsShen, Huaizong, Li, Zhangqiang, Jiang, Yan, Pan, Xiaojing, Wu, Jianping, Cristofori-Armstrong, Ben, Smith, Jennifer J., Chin, Yanni K. Y., Lei, Jianlin, Zhou, Qiang, King, Glenn F. and Yan, Nieng (2018). Structural basis for the modulation of voltage-gated sodium channels by animal toxins. Science, 362 (6412) eaau2596, eaau2596-+. doi: 10.1126/science.aau2596 |
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2018 Journal Article NaV1.1 inhibition can reduce visceral hypersensitivitySalvatierra, Juan, Castro, Joel, Erickson, Andelain, Li, Qian, Braz, Joao, Gilchrist, John, Grundy, Luke, Rychkov, Grigori Y., Deiteren, Annemie, Rais, Rana, King, Glenn F., Slusher, Barbara S., Basbaum, Allan, Pasricha, Pankaj J., Brierley, Stuart M. and Bosmans, Frank (2018). NaV1.1 inhibition can reduce visceral hypersensitivity. JCI Insight, 3 (11) e121000. doi: 10.1172/jci.insight.121000 |
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2018 Journal Article Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcaneShivalingamurthy, Suresha G., Anangi, Raveendra, Kalaipandian, Sundaravelpandian, Glassop, Donna, King, Glenn F. and Rae, Anne L. (2018). Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcane. Frontiers in Plant Science, 9 598, 598. doi: 10.3389/fpls.2018.00598 |
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2018 Journal Article Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranesAgwa, Akello J., Peigneur, Steve, Chow, Chun Yuen, Lawrence, Nicole, Craik, David J., Tytgat, Jan, King, Glenn F., Henriques, Sonia Troeira and Schroeder, Christina I. (2018). Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes. Journal of Biological Chemistry, 293 (23), 9041-9052. doi: 10.1074/jbc.RA118.002553 |
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2018 Journal Article Harvesting venom toxins from assassin bugs and other heteropteran insectsWalker, Andrew Allan, Rosenthal, Max, Undheim, Eivind E. A. and King, Glenn F (2018). Harvesting venom toxins from assassin bugs and other heteropteran insects. Journal of Visualized Experiments, 2018 (134) e57729. doi: 10.3791/57729 |
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2018 Journal Article The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumensWalker, Andrew A., Mayhew, Mark L., Jin, Jiayi, Herzig, Volker, Undheim, Eivind A. B., Sombke, Andy, Fry, Bryan G., Meritt, David J. and King, Glenn F. (2018). The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens. Nature Communications, 9 (1) 755, 755. doi: 10.1038/s41467-018-03091-5 |
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2018 Journal Article Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cellsFernandez-Rojo, Manuel A., Deplazes, Evelyne, Pineda, Sandy S., Brust, Andreas, Marth, Tano, Wilhelm, Patrick, Martel, Nick, Ramm, Grant A., Mancera, Ricardo L., Alewood, Paul F., Woods, Gregory M., Belov, Katherine, Miles, John J., King, Glenn F. and Ikonomopoulou, Maria P. (2018). Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells. Cell Death Discovery, 4 (1) 19, 19. doi: 10.1038/s41420-018-0030-0 |
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2018 Journal Article Giant fish-killing water bug reveals ancient and dynamic venom evolution in HeteropteraWalker, Andrew A., Hernández-Vargas, Maria José, Corzo, Gerardo, Fry, Bryan G. and King, Glenn F. (2018). Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera. Cellular and Molecular Life Sciences, 75 (17), 1-15. doi: 10.1007/s00018-018-2768-1 |
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2018 Journal Article Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory painLee, Jia Yu Peppermint, Saez, Natalie J., Cristofori-Armstrong, Ben, Anangi, Raveendra, King, Glenn F., Smith, Maree T. and Rash, Lachlan D. (2018). Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain. British Journal of Pharmacology, 175 (12), 2204-2218. doi: 10.1111/bph.14089 |
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2017 Journal Article The North American Society of Toxinology establishes formal affiliation with ToxiconKeyler, Daniel E. and King, Glenn F. (2017). The North American Society of Toxinology establishes formal affiliation with Toxicon. Toxicon, 142, A1-A1. doi: 10.1016/j.toxicon.2017.11.009 |
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2017 Journal Article ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxinsPineda, Sandy S., Chaumeil, Pierre-Alain, Kunert, Anne, Kaas, Quentin, Thang, Mike W. C., Le, Lien, Nuhn, Michael, Herzig, Volker, Saez, Natalie J., Cristofori-Armstrong, Ben, Anangi, Raveendra, Senff, Sebastian, Gorse, Dominique and King, Glenn F. (2017). ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins. Bioinformatics, 34 (6), 1074-1076. doi: 10.1093/bioinformatics/btx661 |
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2017 Journal Article Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingiSousa, Silmara R., Wingerd, Joshua S., Brust, Andreas, Bladen, Christopher, Ragnarsson, Lotten, Herzig, Volker, Deuis, Jennifer R., Dutertre, Sebastien, Vetter, Irina, Zamponi, Gerald W., King, Glenn F., Alewood, Paul F. and Lewis, Richard J. (2017). Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi. PLoS One, 12 (9) e0182848, e0182848. doi: 10.1371/journal.pone.0182848 |
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2017 Journal Article Revisiting venom of the sea anemone Stichodactyla haddoni: omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genusMadio, Bruno, Undheim, Eivind A. B. and King, Glenn F. (2017). Revisiting venom of the sea anemone Stichodactyla haddoni: omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus. Journal of Proteomics, 166, 83-92. doi: 10.1016/j.jprot.2017.07.007 |
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2017 Journal Article Improved efficacy of an arthropod toxin expressing fungus against insecticide-resistant malaria-vector mosquitoesBilgo, Etienne, Lovett, Brian, Fang, Weiguo, Bende, Niraj, King, Glenn F., Diabate, Abdoulaye and St Leger, Raymond J. (2017). Improved efficacy of an arthropod toxin expressing fungus against insecticide-resistant malaria-vector mosquitoes. Scientific Reports, 7 (1) 3433, 3433. doi: 10.1038/s41598-017-03399-0 |
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2017 Journal Article Corrigendum: Pharmacological characterisation of the highly Na v 1.7 selective spider venom peptide Pn3a (Scientific Reports (2017) 7 (40883)Deuis, Jennifer R., Dekan, Zoltan, Wingerd, Joshua S., Smith, Jennifer J., Munasinghe, Nehan R., Bhola, Rebecca F., Imlach, Wendy L., Herzig, Volker, Armstrong, David A., Rosengren, K. Johan, Bosmans, Frank, Waxman, Stephen G., Dib-Hajj, Sulayman D., Escoubas, Pierre, Minett, Michael S., Christie, Macdonald J., King, Glenn F., Alewood, Paul F., Lewis, Richard J., Wood, John N. and Vetter, Irina (2017). Corrigendum: Pharmacological characterisation of the highly Na v 1.7 selective spider venom peptide Pn3a (Scientific Reports (2017) 7 (40883). Scientific Reports, 7 (1) 46816, 46816. doi: 10.1038/srep46816 |
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2017 Journal Article Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatusCardoso, Fernanda Caldas, Dekan, Zoltan, Smith, Jennifer J., Deuis, Jennifer R., Vetter, Irina, Herzig, Volker, Alewood, Paul F., King, Glenn F and Lewis, Richard J. (2017). Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus. British Journal of Pharmacology, 174 (15), 2528-2544. doi: 10.1111/bph.13865 |
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2017 Journal Article Insect-active toxins with promiscuous pharmacology from the African theraphosid spider Monocentropus balfouriSmith, Jennifer J., Herzig, Volker, Ikonomopoulou, Maria P., Dziemborowicz, Slawomir, Bosmans, Frank, Nicholson, Graham M. and King, Glenn F. (2017). Insect-active toxins with promiscuous pharmacology from the African theraphosid spider Monocentropus balfouri. Toxins, 9 (5) 155, 155. doi: 10.3390/toxins9050155 |