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2018

Journal Article

NaV1.1 inhibition can reduce visceral hypersensitivity

Salvatierra, Juan, Castro, Joel, Erickson, Andelain, Li, Qian, Braz, Joao, Gilchrist, John, Grundy, Luke, Rychkov, Grigori Y., Deiteren, Annemie, Rais, Rana, King, Glenn F., Slusher, Barbara S., Basbaum, Allan, Pasricha, Pankaj J., Brierley, Stuart M. and Bosmans, Frank (2018). NaV1.1 inhibition can reduce visceral hypersensitivity. JCI Insight, 3 (11) e121000. doi: 10.1172/jci.insight.121000

NaV1.1 inhibition can reduce visceral hypersensitivity

2018

Journal Article

Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcane

Shivalingamurthy, Suresha G., Anangi, Raveendra, Kalaipandian, Sundaravelpandian, Glassop, Donna, King, Glenn F. and Rae, Anne L. (2018). Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcane. Frontiers in Plant Science, 9 598, 598. doi: 10.3389/fpls.2018.00598

Identification and functional characterization of sugarcane invertase inhibitor (ShINH1): a potential candidate for reducing pre- and post-harvest loss of sucrose in sugarcane

2018

Journal Article

Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes

Agwa, Akello J., Peigneur, Steve, Chow, Chun Yuen, Lawrence, Nicole, Craik, David J., Tytgat, Jan, King, Glenn F., Henriques, Sonia Troeira and Schroeder, Christina I. (2018). Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes. Journal of Biological Chemistry, 293 (23), 9041-9052. doi: 10.1074/jbc.RA118.002553

Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes

2018

Journal Article

Harvesting venom toxins from assassin bugs and other heteropteran insects

Walker, Andrew Allan, Rosenthal, Max, Undheim, Eivind E. A. and King, Glenn F (2018). Harvesting venom toxins from assassin bugs and other heteropteran insects. Journal of Visualized Experiments, 2018 (134) e57729. doi: 10.3791/57729

Harvesting venom toxins from assassin bugs and other heteropteran insects

2018

Journal Article

The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens

Walker, Andrew A., Mayhew, Mark L., Jin, Jiayi, Herzig, Volker, Undheim, Eivind A. B., Sombke, Andy, Fry, Bryan G., Meritt, David J. and King, Glenn F. (2018). The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens. Nature Communications, 9 (1) 755, 755. doi: 10.1038/s41467-018-03091-5

The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens

2018

Journal Article

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells

Fernandez-Rojo, Manuel A., Deplazes, Evelyne, Pineda, Sandy S., Brust, Andreas, Marth, Tano, Wilhelm, Patrick, Martel, Nick, Ramm, Grant A., Mancera, Ricardo L., Alewood, Paul F., Woods, Gregory M., Belov, Katherine, Miles, John J., King, Glenn F. and Ikonomopoulou, Maria P. (2018). Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells. Cell Death Discovery, 4 (1) 19, 19. doi: 10.1038/s41420-018-0030-0

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells

2018

Journal Article

Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera

Walker, Andrew A., Hernández-Vargas, Maria José, Corzo, Gerardo, Fry, Bryan G. and King, Glenn F. (2018). Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera. Cellular and Molecular Life Sciences, 75 (17), 1-15. doi: 10.1007/s00018-018-2768-1

Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera

2018

Journal Article

Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain

Lee, Jia Yu Peppermint, Saez, Natalie J., Cristofori-Armstrong, Ben, Anangi, Raveendra, King, Glenn F., Smith, Maree T. and Rash, Lachlan D. (2018). Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain. British Journal of Pharmacology, 175 (12), 2204-2218. doi: 10.1111/bph.14089

Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain

2017

Journal Article

The North American Society of Toxinology establishes formal affiliation with Toxicon

Keyler, Daniel E. and King, Glenn F. (2017). The North American Society of Toxinology establishes formal affiliation with Toxicon. Toxicon, 142, A1-A1. doi: 10.1016/j.toxicon.2017.11.009

The North American Society of Toxinology establishes formal affiliation with Toxicon

2017

Journal Article

ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins

Pineda, Sandy S., Chaumeil, Pierre-Alain, Kunert, Anne, Kaas, Quentin, Thang, Mike W. C., Le, Lien, Nuhn, Michael, Herzig, Volker, Saez, Natalie J., Cristofori-Armstrong, Ben, Anangi, Raveendra, Senff, Sebastian, Gorse, Dominique and King, Glenn F. (2017). ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins. Bioinformatics, 34 (6), 1074-1076. doi: 10.1093/bioinformatics/btx661

ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins

2017

Journal Article

Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi

Sousa, Silmara R., Wingerd, Joshua S., Brust, Andreas, Bladen, Christopher, Ragnarsson, Lotten, Herzig, Volker, Deuis, Jennifer R., Dutertre, Sebastien, Vetter, Irina, Zamponi, Gerald W., King, Glenn F., Alewood, Paul F. and Lewis, Richard J. (2017). Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi. PLoS One, 12 (9) e0182848, e0182848. doi: 10.1371/journal.pone.0182848

Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi

2017

Journal Article

Revisiting venom of the sea anemone Stichodactyla haddoni: omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus

Madio, Bruno, Undheim, Eivind A. B. and King, Glenn F. (2017). Revisiting venom of the sea anemone Stichodactyla haddoni: omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus. Journal of Proteomics, 166, 83-92. doi: 10.1016/j.jprot.2017.07.007

Revisiting venom of the sea anemone Stichodactyla haddoni: omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus

2017

Journal Article

Improved efficacy of an arthropod toxin expressing fungus against insecticide-resistant malaria-vector mosquitoes

Bilgo, Etienne, Lovett, Brian, Fang, Weiguo, Bende, Niraj, King, Glenn F., Diabate, Abdoulaye and St Leger, Raymond J. (2017). Improved efficacy of an arthropod toxin expressing fungus against insecticide-resistant malaria-vector mosquitoes. Scientific Reports, 7 (1) 3433, 3433. doi: 10.1038/s41598-017-03399-0

Improved efficacy of an arthropod toxin expressing fungus against insecticide-resistant malaria-vector mosquitoes

2017

Journal Article

Corrigendum: Pharmacological characterisation of the highly Na v 1.7 selective spider venom peptide Pn3a (Scientific Reports (2017) 7 (40883)

Deuis, Jennifer R., Dekan, Zoltan, Wingerd, Joshua S., Smith, Jennifer J., Munasinghe, Nehan R., Bhola, Rebecca F., Imlach, Wendy L., Herzig, Volker, Armstrong, David A., Rosengren, K. Johan, Bosmans, Frank, Waxman, Stephen G., Dib-Hajj, Sulayman D., Escoubas, Pierre, Minett, Michael S., Christie, Macdonald J., King, Glenn F., Alewood, Paul F., Lewis, Richard J., Wood, John N. and Vetter, Irina (2017). Corrigendum: Pharmacological characterisation of the highly Na v 1.7 selective spider venom peptide Pn3a (Scientific Reports (2017) 7 (40883). Scientific Reports, 7 (1) 46816, 46816. doi: 10.1038/srep46816

Corrigendum: Pharmacological characterisation of the highly Na v 1.7 selective spider venom peptide Pn3a (Scientific Reports (2017) 7 (40883)

2017

Journal Article

Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus

Cardoso, Fernanda Caldas, Dekan, Zoltan, Smith, Jennifer J., Deuis, Jennifer R., Vetter, Irina, Herzig, Volker, Alewood, Paul F., King, Glenn F and Lewis, Richard J. (2017). Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus. British Journal of Pharmacology, 174 (15), 2528-2544. doi: 10.1111/bph.13865

Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus

2017

Journal Article

Insect-active toxins with promiscuous pharmacology from the African theraphosid spider Monocentropus balfouri

Smith, Jennifer J., Herzig, Volker, Ikonomopoulou, Maria P., Dziemborowicz, Slawomir, Bosmans, Frank, Nicholson, Graham M. and King, Glenn F. (2017). Insect-active toxins with promiscuous pharmacology from the African theraphosid spider Monocentropus balfouri. Toxins, 9 (5) 155, 155. doi: 10.3390/toxins9050155

Insect-active toxins with promiscuous pharmacology from the African theraphosid spider Monocentropus balfouri

2017

Journal Article

Melt with this kiss: paralyzing and liquefying venom of the assassin bug Pristhesancus plagipennis (Hemiptera: Reduviidae)

Walker, Andrew A. , Madio, Bruno, Jin, Jiayi, Undheim, Eivind A. B. , Fry, Bryan G. and King, Glenn F. (2017). Melt with this kiss: paralyzing and liquefying venom of the assassin bug Pristhesancus plagipennis (Hemiptera: Reduviidae). Molecular and Cellular Proteomics, 16 (4), 552-566. doi: 10.1074/mcp.M116.063321

Melt with this kiss: paralyzing and liquefying venom of the assassin bug Pristhesancus plagipennis (Hemiptera: Reduviidae)

2017

Journal Article

Venom profiling of a population of the theraphosid spider Phlogius crassipes reveals continuous ontogenetic changes from juveniles through adulthood

Santana, Renan C., Perez, David, Dobson, James, Panagides, Nadya, Raven, Robert J., Nouwens, Amanda, Jones, Alun, King, Glenn F. and Fry, Bryan G. (2017). Venom profiling of a population of the theraphosid spider Phlogius crassipes reveals continuous ontogenetic changes from juveniles through adulthood. Toxins, 9 (4) 116, 116. doi: 10.3390/toxins9040116

Venom profiling of a population of the theraphosid spider Phlogius crassipes reveals continuous ontogenetic changes from juveniles through adulthood

2017

Journal Article

The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variant

Rahnama, Sassan, Deuis, Jennifer R., Cardoso, Fernanda C., Ramanujam, Venkatraman, Lewis, Richard J., Rash, Lachlan D., King, Glenn F., Vetter, Irina and Mobli, Mehdi (2017). The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variant. PLoS One, 12 (3) e0173551, e0173551. doi: 10.1371/journal.pone.0173551

The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variant

2017

Journal Article

Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a

Chassagnon, Irene R., McCarthy, Claudia A., Chin, Yanni K.-Y., Pineda, Sandy S., Keramidas, Angelo, Mobli, Mehdi, Pham, Vi, De Silva, T. Michael, Lynch, Joseph W., Widdop, Robert E., Rash, Lachlan D. and King, Glenn F. (2017). Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a. Proceedings from the National Academy of Sciences of the United States of America, 114 (14), 3750-3755. doi: 10.1073/pnas.1614728114

Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a