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2020 Journal Article Antimicrobial resistance in ESKAPE pathogensDe Oliveira, David M. P., Forde, Brian M., Kidd, Timothy J., Harris, Patrick N. A., Schembri, Mark A., Beatson, Scott A., Paterson, David L. and Walker, Mark J. (2020). Antimicrobial resistance in ESKAPE pathogens. Clinical Microbiology Reviews, 33 (3) e00181-19, e00181-19. doi: 10.1128/cmr.00181-19 |
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2020 Journal Article Update on group A streptococcal vaccine developmentDale, James B. and Walker, Mark J. (2020). Update on group A streptococcal vaccine development. Current Opinion in Infectious Diseases, 33 (3), 244-250. doi: 10.1097/QCO.0000000000000644 |
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2020 Journal Article All major cholesterol-dependent cytolysins use glycans as cellular receptorsShewell, Lucy K., Day, Christopher J., Jen, Freda E.-C., Haselhorst, Thomas, Atack, John M., Reijneveld, Josephine F., Everest-Dass, Arun, James, David B. A., Boguslawski, Kristina M., Brouwer, Stephan, Gillen, Christine M., Luo, Zhenyao, Kobe, Bostjan, Nizet, Victor, von Itzstein, Mark, Walker, Mark J., Paton, Adrienne W., Paton, James C., Torres, Victor J. and Jennings, Michael P. (2020). All major cholesterol-dependent cytolysins use glycans as cellular receptors. Science Advances, 6 (21) EAAZ4926, eaaz4926. doi: 10.1126/sciadv.aaz4926 |
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2020 Journal Article Multiple bactericidal mechanisms of the zinc ionophore PBT2Harbison-Price, Nichaela, Ferguson, Scott A., Heikal, Adam, Taiaroa, George, Hards, Kiel, Nakatani, Yoshio, Rennison, David, Brimble, Margaret A., El-Deeb, Ibrahim M., Bohlmann, Lisa, McDevitt, Christopher A., von Itzstein, Mark, Walker, Mark J. and Cook, Gregory M. (2020). Multiple bactericidal mechanisms of the zinc ionophore PBT2. mSphere, 5 (2) e00157-20. doi: 10.1128/msphere.00157-20 |
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2020 Journal Article Vaccine-induced Th1-type response protects against invasive group A Streptococcus infection in the absence of opsonizing antibodiesRivera-Hernandez, Tania, Rhyme, Mira Syahira, Cork, Amanda J., Jones, Scott, Segui-Perez, Celia, Brunner, Livia, Richter, Johanna, Petrovsky, Nikolai, Lawrenz, Maria, Goldblatt, David, Collin, Nicolas and Walker, Mark J. (2020). Vaccine-induced Th1-type response protects against invasive group A Streptococcus infection in the absence of opsonizing antibodies. mBio, 11 (2) e00122-20. doi: 10.1128/mbio.00122-20 |
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2020 Journal Article Updated emm-typing protocol for Streptococcus pyogenesFrost, H. R., Davies, M. R., Velusamy, S., Delforge, V., Erhart, A., Darboe, S., Steer, A., Walker, M. J., Beall, B., Botteaux, A. and Smeesters, P. R. (2020). Updated emm-typing protocol for Streptococcus pyogenes. Clinical Microbiology and Infection, 26 (7) 946.e5, 946.e5-946.e8. doi: 10.1016/j.cmi.2020.02.026 |
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2020 Journal Article Semisynthetic, self-adjuvanting vaccine development: efficient, site-specific sortase A-mediated conjugation of Toll-like receptor 2 ligand FSL-1 to recombinant protein antigens under native conditions and application to a model group A streptococcal vaccineXu, Zhenghui, Rivera-Hernandez, Tania, Chatterjee, Oishee, Walker, Mark J. and Moyle, Peter M. (2020). Semisynthetic, self-adjuvanting vaccine development: efficient, site-specific sortase A-mediated conjugation of Toll-like receptor 2 ligand FSL-1 to recombinant protein antigens under native conditions and application to a model group A streptococcal vaccine. Journal of Controlled Release, 317, 96-108. doi: 10.1016/j.jconrel.2019.11.018 |
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2020 Journal Article Analysis of global collection of group A Streptococcus genomes reveals that the majority encode a trio of M and M-like proteinsFrost, Hannah R., Davies, Mark R., Delforge, Valérie, Lakhloufi, Dalila, Sanderson-Smith, Martina, Srinivasan, Velusamy, Steer, Andrew C., Walker, Mark J., Beall, Bernard, Botteaux, Anne and Smeesters, Pierre R. (2020). Analysis of global collection of group A Streptococcus genomes reveals that the majority encode a trio of M and M-like proteins. mSphere, 5 (1) e00806. doi: 10.1128/mSphere.00806-19 |
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2020 Journal Article Neisseria gonorrhoeae becomes susceptible to polymyxin B and colistin in the presence of PBT2Jen, Freda E.-C., Everest-Dass, Arun V., El-Deeb, Ibrahim M., Singh, Sanjesh, Haselhorst, Thomas, Walker, Mark J., Von Itzstein, Mark and Jennings, Michael P. (2020). Neisseria gonorrhoeae becomes susceptible to polymyxin B and colistin in the presence of PBT2. ACS Infectious Diseases, 6 (1), 50-55. doi: 10.1021/acsinfecdis.9b00307 |
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2019 Journal Article Increased incidence of scarlet fever — China, 1999−2018You, Yuanhai, Qin, Ying, Walker, Mark J., Feng, Luzhao and Zhang, Jianzhong (2019). Increased incidence of scarlet fever — China, 1999−2018. China CDC Weekly, 1 (5), 63-66. doi: 10.46234/ccdcw2019.019 |
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2019 Journal Article Characterizing the role of tissue-type plasminogen activator in a mouse model of Group A streptococcal infectionLy, Diane, Donahue, Deborah, Walker, Mark J., Ploplis, Victoria A., McArthur, Jason D., Ranson, Marie, Castellino, Francis J. and Sanderson-Smith, Martina L. (2019). Characterizing the role of tissue-type plasminogen activator in a mouse model of Group A streptococcal infection. Microbes and Infection, 21 (8-9), 412-417. doi: 10.1016/j.micinf.2019.04.004 |
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2019 Journal Article Scarlet fever changes its spotsBrouwer, Stephan, Lacey, Jake A., You, Yuanhai, Davies, Mark R. and Walker, Mark J. (2019). Scarlet fever changes its spots. Lancet Infectious Diseases, 19 (11), 1154-1155. doi: 10.1016/S1473-3099(19)30494-3 |
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2019 Journal Article Human glycan expression patterns influence Group A streptococcal colonization of epithelial cellsDe Oliveira, David M. P., Everest-Dass, Arun, Hartley-Tassell, Lauren, Day, Christopher J., Indraratna, Anuk, Brouwer, Stephan, Cleary, Ailish, Kautto, Liisa, Gorman, Jody, Packer, Nicolle H., Jennings, Michael P., Walker, Mark J. and Sanderson-Smith, Martina L. (2019). Human glycan expression patterns influence Group A streptococcal colonization of epithelial cells. FASEB Journal, 33 (10), 10808-10818. doi: 10.1096/fj.201900559R |
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2019 Journal Article The serotype-specific role of regulator of cov polymorphisms in the pathogenesis of invasive group a streptococcal infectionsBrouwer, Stephan and Walker, Mark J. (2019). The serotype-specific role of regulator of cov polymorphisms in the pathogenesis of invasive group a streptococcal infections. American Journal of Pathology, 189 (10), 1913-1915. doi: 10.1016/j.ajpath.2019.07.005 |
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2019 Journal Article Author correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomicsDavies, Mark R., McIntyre, Liam, Mutreja, Ankur, Lacey, Jake A., Lees, John A., Towers, Rebecca J., Duchêne, Sebastián, Smeesters, Pierre R., Frost, Hannah R., Price, David J., Holden, Matthew T. G., David, Sophia, Giffard, Philip M., Worthing, Kate A., Seale, Anna C., Berkley, James A., Harris, Simon R., Rivera-Hernandez, Tania, Berking, Olga, Cork, Amanda J., Torres, Rosângela S. L. A., Lithgow, Trevor, Strugnell, Richard A., Bergmann, Rene, Nitsche-Schmitz, Patric, Chhatwal, Gusharan S., Bentley, Stephen D., Fraser, John D., Moreland, Nicole J. ... Walker, Mark J. (2019). Author correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics. Nature Genetics, 51 (8), 1295-1295. doi: 10.1038/s41588-019-0482-z |
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2019 Journal Article Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomicsDavies, Mark R., McIntyre, Liam, Mutreja, Ankur, Lacey, Jake A., Lees, John A., Towers, Rebecca J., Duchêne, Sebastián, Smeesters, Pierre R., Frost, Hannah R., Price, David J., Holden, Matthew T. G., David, Sophia, Giffard, Philip M., Worthing, Kate A., Seale, Anna C., Berkley, James A., Harris, Simon R., Rivera-Hernandez, Tania, Berking, Olga, Cork, Amanda J., Torres, Rosângela S. L. A., Lithgow, Trevor, Strugnell, Richard A., Bergmann, Rene, Nitsche-Schmitz, Patric, Chhatwal, Gusharan S., Bentley, Stephen D., Fraser, John D., Moreland, Nicole J. ... Walker, Mark J. (2019). Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics. Nature Genetics, 51 (6), 1035-1043. doi: 10.1038/s41588-019-0417-8 |
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2019 Journal Article Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection studyOsowicki, Joshua, Azzopardi, Kristy I., Baker, Ciara, Waddington, Claire S., Pandey, Manisha, Schuster, Tibor, Grobler, Anneke, Cheng, Allen C., Pollard, Andrew J., McCarthy, James S., Good, Michael F., Walker, Mark J., Dale, James B., Batzloff, Michael R., Carapetis, Jonathan R., Smeesters, Pierre R. and Steer, Andrew C. (2019). Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study. Vaccine, 37 (26), 3485-3494. doi: 10.1016/j.vaccine.2019.03.059 |
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2019 Journal Article An experimental Group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate modelRivera-Hernandez, Tania, Carnathan, Diane G., Jones, Scott, Cork, Amanda J., Davies, Mark R., Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., McCarthy, James, Nizet, Victor, Goldblatt, David, Silvestri, Guido and Walker, Mark J. (2019). An experimental Group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model. mBio, 10 (2) e00693-19. doi: 10.1128/mBio.00693-19 |
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2019 Journal Article Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharidesEdgar, Rebecca J., van Hensbergen, Vincent P., Ruda, Alessandro, Turner, Andrew G., Deng, Pan, Le Breton, Yoann, El-Sayed, Najib M., Belew, Ashton T., McIver, Kevin S., McEwan, Alastair G., Morris, Andrew J., Lambeau, Gérard, Walker, Mark J., Rush, Jeffrey S., Korotkov, Konstantin V., Widmalm, Göran, van Sorge, Nina M. and Korotkova, Natalia (2019). Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides. Nature Chemical Biology, 15 (5), 463-471. doi: 10.1038/s41589-019-0251-4 |
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2019 Journal Article Group A Streptococcus co-ordinates manganese import and iron efflux in response to hydrogen peroxide stressTurner, Andrew G., Djoko, Karrera Y., Ong, Cheryl-Lynn Y., Barnett, Timothy C., Walker, Mark J. and McEwan, Alastair G. (2019). Group A Streptococcus co-ordinates manganese import and iron efflux in response to hydrogen peroxide stress. Biochemical Journal, 476 (3), 595-611. doi: 10.1042/BCJ20180902 |
