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2014

Journal Article

Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing

Ly, Diane, Taylor, Jude M., Tsatsaronis, James A., Monteleone, Mercedes M., Skora, Amanda S., Donald, Cortny A., Maddocks, Tracy, Nizet, Victor, West, Nicholas P., Ranson, Marie, Walker, Mark J., McArthur, Jason D. and Sanderson-Smith, Martina L. (2014). Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing. Journal of Innate Immunity, 6 (2), 240-250. doi: 10.1159/000353754

Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing

2014

Conference Publication

Genetics and virulence role of the classical group A Streptococcus Lancefield antigen

Cole, Jason, van Sorge, Nina, Kuipers, Kirsten, Henningham, Anna, Aziz, Ramy, Kasirer-Friede, Ana, Lin, Leo, Berends, Evelien, Davies, Mark, Dougan, Gordan, Zhang, Fan, Dahesh, Samira, Shaw, Laura, Gin, Jennifer, Cunningham, Madeleine, Merriman, Joseph, Rooijakkers, Suzan, Malley, Richard, Walker, Mark, Shattil, Sanford, Schlievert, Patrick, Choudhury, Biswa and Nizet, Victor (2014). Genetics and virulence role of the classical group A Streptococcus Lancefield antigen. Experimental Biology Meeting, San Diego Ca, 26-30 April 2014. Federation of American Societies for Experimental Biology.

Genetics and virulence role of the classical group A Streptococcus Lancefield antigen

2014

Journal Article

Disease manifestations and pathogenic mechanisms of group A Streptococcus

Walker, Mark J., Barnett, Timothy C., McArthur, Jason D., Cole, Jason N., Gillen, Christine M., Henningham, Anna, Sriprakash, K. S., Sanderson-Smith, Martina L. and Nizet, Victor (2014). Disease manifestations and pathogenic mechanisms of group A Streptococcus. Clinical Microbiology Reviews, 27 (2), 264-301. doi: 10.1128/CMR.00101-13

Disease manifestations and pathogenic mechanisms of group A Streptococcus

2013

Journal Article

The globally disseminated M1T1 clone of Group A Streptococcus evades autophagy for intracellular replication

Barnett, Timothy C., Liebl, David, Seymour, Lisa M., Gillen, Christine M., Lim, Jin Yan, LaRock, Christopher N., Davies, Mark R., Schulz, Benjamin L., Nizet, Victor, Teasdale, Rohan D. and Walker, Mark J. (2013). The globally disseminated M1T1 clone of Group A Streptococcus evades autophagy for intracellular replication. Cell Host and Microbe, 14 (6), 675-682. doi: 10.1016/j.chom.2013.11.003

The globally disseminated M1T1 clone of Group A Streptococcus evades autophagy for intracellular replication

2013

Journal Article

Sequences of two related multiple antibiotic resistance virulence plasmids sharing a unique IS26-related molecular signature isolated from different Escherichia coli pathotypes from different hosts

Venturini, Carola, Hassan, Karl A., Chowdhury, Piklu Roy, Paulsen, Ian T., Walker, Mark J. and Djordjevic, Steven P. (2013). Sequences of two related multiple antibiotic resistance virulence plasmids sharing a unique IS26-related molecular signature isolated from different Escherichia coli pathotypes from different hosts. PLoS ONE, 8 (11) e78862, e78862.1-e78862.14. doi: 10.1371/journal.pone.0078862

Sequences of two related multiple antibiotic resistance virulence plasmids sharing a unique IS26-related molecular signature isolated from different Escherichia coli pathotypes from different hosts

2013

Journal Article

Extensive diversity of Streptococcus pyogenes in a remote human population reflects global-scale transmission rather than localised diversification

Towers, Rebecca J., Carapetis, Jonathan R., Currie, Bart J., Davies, Mark R., Walker, Mark J., Dougan, Gordon and Giffard, Philip M. (2013). Extensive diversity of Streptococcus pyogenes in a remote human population reflects global-scale transmission rather than localised diversification. PLoS One, 8 (9) e73851, e73851.1-e73851.6. doi: 10.1371/journal.pone.0073851

Extensive diversity of Streptococcus pyogenes in a remote human population reflects global-scale transmission rather than localised diversification

2013

Journal Article

Structure-informed design of an enzymatically inactive vaccine component for group A Streptococcus

Henningham, Anna, Ericsson, Daniel J., Langer, Karla, Casey, Lachlan W., Jovcevski, Blagojce, Singh Chhatwal, G., Aquilina, J. Andrew, Batzloff, Michael R., Kobe, Bostjan and Walker, Mark J. (2013). Structure-informed design of an enzymatically inactive vaccine component for group A Streptococcus. mBio, 4 (4) e00509-13. doi: 10.1128/mBio.00509-13

Structure-informed design of an enzymatically inactive vaccine component for group A Streptococcus

2013

Journal Article

A key role for the urokinase Plasminogen Activator (uPA) in invasive Group A streptococcal infection

Sanderson-Smith, Martina L., Zhang, Yueling, Ly, Diane, Donahue, Deborah, Hollands, Andrew, Nizet, Victor, Ranson, Marie, Ploplis, Victoria A., Walker, Mark J. and Castellino, Francis J. (2013). A key role for the urokinase Plasminogen Activator (uPA) in invasive Group A streptococcal infection. PLoS Pathogens, 9 (7) e1003469, e1003469.1-e1003469.9. doi: 10.1371/journal.ppat.1003469

A key role for the urokinase Plasminogen Activator (uPA) in invasive Group A streptococcal infection

2013

Journal Article

Molecular characterization of endocarditis-associated Staphylococcus aureus

Nethercott, Cara, Mabbett, Amanda N., Totsika, Makrina, Peters, Paul, Ortiz, Juan C., Nimmo, Graeme R., Coombs, Geoffrey W., Walker, Mark J. and Schembri, Mark A. (2013). Molecular characterization of endocarditis-associated Staphylococcus aureus. Journal of Clinical Microbiology, 51 (7), 2131-2138. doi: 10.1128/JCM.00651-13

Molecular characterization of endocarditis-associated Staphylococcus aureus

2013

Journal Article

Acquisition of the Sda1-encoding bacteriophage does not enhance virulence of the serotype M1 Streptococcus pyogenes strain SF370

Venturini, Carola, Ong, Cheryl-Iynn Y., Gillen, Christine M., Ben-Zakour, Nouri L., Maamary, Peter G., Nizet, Victor, Beatson, Scott A. and Walker, Mark J. (2013). Acquisition of the Sda1-encoding bacteriophage does not enhance virulence of the serotype M1 Streptococcus pyogenes strain SF370. Infection and Immunity, 81 (6), 2062-2069. doi: 10.1128/IAI.00192-13

Acquisition of the Sda1-encoding bacteriophage does not enhance virulence of the serotype M1 Streptococcus pyogenes strain SF370

2013

Journal Article

Interplay between manganese and iron in pneumococcal pathogenesis: role of the orphan response regulator RitR

Ong, Cheryl-lynn Y., Potter, Adam J., Trappetti, Claudia, Walker, Mark J., Jennings, Michael P., Paton, James C. and McEwan, Alastair G. (2013). Interplay between manganese and iron in pneumococcal pathogenesis: role of the orphan response regulator RitR. Infection and Immunity, 81 (2), 421-429. doi: 10.1128/IAI.00805-12

Interplay between manganese and iron in pneumococcal pathogenesis: role of the orphan response regulator RitR

2013

Book Chapter

Group A streptococcal vaccine candidates: potential for the development of a human vaccine

Henningham, Anna, Gillen, Christine M. and Walker, Mark J. (2013). Group A streptococcal vaccine candidates: potential for the development of a human vaccine. Host-pathogen interactions in streptococcal diseases. (pp. 207-242) edited by G. Singh Chhatwal. New York, NY, United States: Springer. doi: 10.1007/82_2012_284

Group A streptococcal vaccine candidates: potential for the development of a human vaccine

2013

Journal Article

Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus

Tsatsaronis, James A., Hollands, Andrew, Cole, Jason N., Maamary, Peter G., Gillen, Christine M., Ben Zakour, Nouri L., Kotb, Malak, Nizet, Victor, Beatson, Scott A., Mark J. Walker and Sanderson-Smith, Martina L. (2013). Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus. FASEB Journal, 27 (7), 2633-2643. doi: 10.1096/fj.12-226662

Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus

2012

Journal Article

Evaluation of clinical, histological and immunological changes and qPCR detection of Mycoplasma hyopneumoniae in tissues during the early stages of mycoplasmal pneumonia in pigs after experimental challenge with two field isolates

Woolley, Lauren K., Fell, Shayne, Gonsalves, Jocelyn R., Walker, Mark J., Djordjevic, Steven P., Jenkins, Cheryl and Eamens, Graeme J. (2012). Evaluation of clinical, histological and immunological changes and qPCR detection of Mycoplasma hyopneumoniae in tissues during the early stages of mycoplasmal pneumonia in pigs after experimental challenge with two field isolates. Veterinary Microbiology, 161 (1-2), 186-195. doi: 10.1016/j.vetmic.2012.07.025

Evaluation of clinical, histological and immunological changes and qPCR detection of Mycoplasma hyopneumoniae in tissues during the early stages of mycoplasmal pneumonia in pigs after experimental challenge with two field isolates

2012

Journal Article

Streptokinase variants from Streptococcus pyogenes isolates display altered plasminogen activation characteristics - implications for pathogenesis

Cook, Simon M., Skora, Amanda, Gillen, Christine M., Walker, Mark J. and McArthur, Jason D. (2012). Streptokinase variants from Streptococcus pyogenes isolates display altered plasminogen activation characteristics - implications for pathogenesis. Molecular Microbiology, 86 (5), 1052-1062. doi: 10.1111/mmi.12037

Streptokinase variants from Streptococcus pyogenes isolates display altered plasminogen activation characteristics - implications for pathogenesis

2012

Journal Article

Outsmarting outbreaks

Walker, Mark J. and Beatson, Scott A. (2012). Outsmarting outbreaks. Science, 338 (6111), 1161-1162. doi: 10.1126/science.1232327

Outsmarting outbreaks

2012

Journal Article

Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone

Maamary, Peter G., Ben Zakour, Nouri L., Cole, Jason N., Hollands, Andrew, Aziz, Ramy K., Barnett, Timothy C., Cork, Amanda J., Henningham, Anna, Sanderson-Smith, Martina, McArthur, Jason D., Venturini, Carola, Gillen, Christine M., Kirk, Joshua K., Johnson, Dwight R., Taylor, William L., Kaplan, Edward L., Kotb, Malak, Nizet, Victor, Beatson, Scott A. and Walker, Mark J. (2012). Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone. FASEB Journal, 26 (11), 4675-4684. doi: 10.1096/fj.12-212142

Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone

2012

Journal Article

Molecular characterization of the 2011 Hong Kong scarlet fever outbreak

Tse, Herman, Bao, Jessie Y. J., Davies, Mark R., Maamary, Peter, Tsoi, Hoi-Wah, Tong, Amy H. Y., Ho, Tom C. C., Lin, Chi-Ho, Gillen, Christine M., Barnett, Timothy C., Chen, Jonathan H. K., Lee, Mianne, Yam, Wing-Cheong, Wong, Chi-Kin, Ong, Cheryl-lynn Y., Chan, Yee-Wai, Wu, Cheng-Wei, Ng, Tony, Lim, Wilina W. L., Tsang, Thomas H. F., Tse, Cindy W. S., Dougan, Gordon, Walker, Mark J., Lok, Si and Yuen, Kwok-Yung (2012). Molecular characterization of the 2011 Hong Kong scarlet fever outbreak. The Journal of Infectious Diseases, 206 (3), 341-351. doi: 10.1093/infdis/jis362

Molecular characterization of the 2011 Hong Kong scarlet fever outbreak

2012

Journal Article

Pathogenesis of group A streptococcal infections

Henningham, Anna, Barnett, Timothy C., Maamary, Peter G. and Walker, Mark J. (2012). Pathogenesis of group A streptococcal infections. Discovery Medicine, 13 (72), 329-342.

Pathogenesis of group A streptococcal infections

2012

Journal Article

Characterization of cleavage events in the multifunctional cilium adhesin Mhp684 (P146) reveals a mechanism by which Mycoplasma hyopneumoniae regulates surface topography

Bogema, Daniel R., Deutscher, Ania T., Woolley, Lauren K., Seymour, Lisa M., Raymond, Benjamin B. A., Tacchi, Jessica L., Padula, Matthew P., Dixon, Nicholas E., Minion, F. Chris, Jenkins, Cheryl, Walker, Mark J. and Djordjevic, Steven P. (2012). Characterization of cleavage events in the multifunctional cilium adhesin Mhp684 (P146) reveals a mechanism by which Mycoplasma hyopneumoniae regulates surface topography. mBio, 3 (2) e00282-11, e00282.1-e00282.11. doi: 10.1128/mBio.00282-11

Characterization of cleavage events in the multifunctional cilium adhesin Mhp684 (P146) reveals a mechanism by which Mycoplasma hyopneumoniae regulates surface topography