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2014

Journal Article

The contribution of non-human primate models to the development of human vaccines

Rivera-Hernandez, Tania, Carnathan, Diane G., Moyle, Peter M., Toth, Istvan, West, Nicholas P., Young, Paul L., Silvestri, Guido and Walker, Mark J. (2014). The contribution of non-human primate models to the development of human vaccines. Discovery Medicine, 18 (101), 313-322.

The contribution of non-human primate models to the development of human vaccines

2014

Journal Article

Mutual exclusivity of hyaluronan and hyaluronidase in invasive group a Streptococcus

Henningham, Anna, Yamaguchi, Masaya, Aziz, Ramy K., Kuipers, Kirsten, Buffalo,Cosmo Z., Dahesh, Samira, Choudhury, Biswa, Van Vleet, Jeremy, Yamaguchi, Yuka, Seymour, Lisa M., Ben Zakour, Nouri L., He, Lingjun, Smith, Helen V., Grimwood, Keith, Beatson, Scott A., Ghosh, Partho, Walker, Mark J., Nizet, Victor and Cole, Jason N. (2014). Mutual exclusivity of hyaluronan and hyaluronidase in invasive group a Streptococcus. Journal of Biological Chemistry, 289 (46), 32303-32315. doi: 10.1074/jbc.M114.602847

Mutual exclusivity of hyaluronan and hyaluronidase in invasive group a Streptococcus

2014

Journal Article

The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity.

Shewell, Lucy K., Harvey,Richard M., Higgins, Melanie A., Day, Christopher J., Hartley-Tassell, Lauren E., Chen, Austen Y., Gillen, Christine M., James, David B. A., Alonzo, Francis, Torres, Victor J., Walker, Mark J., Paton, Adrienne W., Paton, James C. and Jennings, Michael P. (2014). The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity.. Proceedings of the National Academy of Sciences of the United State of America, 111 (49), E5312-E5320. doi: 10.1073/pnas.1412703111

The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity.

2014

Journal Article

A systematic and functional classification of Streptococcus pyogenes that serves as a new tool for molecular typing and vaccine development

Sanderson-Smith, Martina, De Oliveira, David M. P., Guglielmini, Julien, McMillan, David J., Vu, Therese, Holien, Jessica K., Henningham, Anna, Steer, Andrew C., Bessen, Debra E., Dale, James B., Curtis, Nigel, Beall, Bernard W., Walker, Mark J., Parker, Michael W., Carapetis, Jonathan R., Van Melderen, Laurence, Sriprakash, Kadaba S. and Smeesters, Pierre R. (2014). A systematic and functional classification of Streptococcus pyogenes that serves as a new tool for molecular typing and vaccine development. The Journal of Infectious Diseases, 210 (8), 1325-1338. doi: 10.1093/infdis/jiu260

A systematic and functional classification of Streptococcus pyogenes that serves as a new tool for molecular typing and vaccine development

2014

Journal Article

Tracking antibiotic resistance

Beatson, Scott A. and Walker, Mark J. (2014). Tracking antibiotic resistance. Science, 345 (6203), 1454-1455. doi: 10.1126/science.1260471

Tracking antibiotic resistance

2014

Journal Article

Host responses to group A Streptococcus: cell death and inflammation

Tsatsaronis, James A., Walker, Mark J. and Sanderson-Smith, Martina L. (2014). Host responses to group A Streptococcus: cell death and inflammation. PLoS Pathogens, 10 (8) e1004266, e1004266.1-e1004266.7. doi: 10.1371/journal.ppat.1004266

Host responses to group A Streptococcus: cell death and inflammation

2014

Journal Article

Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline

Da Cunha, Violette, Davies, Mark R., Douarre, Pierre-Emmanuel, Rosinski-Chupin, Isabelle, Margarit, Immaculada, Spinali, Sebastien, Perkins, Tim, Lechat, Pierre, Dmytruk, Nicolas, Sauvage, Elisabeth, Ma, Laurence, Romi, Benedetta, Tichit, Magali, Lopez-Sanchez, Maria-Jose, Descorps-Declere, Stephane, Souche, Erika, Buchrieser, Carmen, Trieu-Cuot, Patrick, Moszer, Ivan, Clermont, Dominique, Maione, Domenico, Bouchier, Christiane, McMillan, David J., Parkhill, Julian, Telford, John L., Dougan, Gordan, Walker, Mark J., The DEVANI Consortium, Holden, Matthew T. G. ... Glaser, Philippe (2014). Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline. Nature Communications, 5 (1) 4544, 4544.1-4544.11. doi: 10.1038/ncomms5544

Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline

2014

Journal Article

Evaluation of recombinant Mycoplasma hyopneumoniae P97/P102 paralogs formulated with selected adjuvants as vaccines against mycoplasmal pneumonia in pigs

Woolley, Lauren K., Fell, Shayne A., Gonsalves, Jocelyn R., Raymond, Benjamin B. A., Collins, Damian, Kuit, Tracey A., Walker, Mark J., Djordjevic, Steven P., Eamens, Graeme J. and Jenkins, Cheryl (2014). Evaluation of recombinant Mycoplasma hyopneumoniae P97/P102 paralogs formulated with selected adjuvants as vaccines against mycoplasmal pneumonia in pigs. Vaccine, 32 (34), 4333-4341. doi: 10.1016/j.vaccine.2014.06.008

Evaluation of recombinant Mycoplasma hyopneumoniae P97/P102 paralogs formulated with selected adjuvants as vaccines against mycoplasmal pneumonia in pigs

2014

Journal Article

Working towards a Group A Streptococcal vaccine: report of a collaborative Trans-Tasman workshop

Moreland, Nicole J., Waddington, Claire S., Williamson, Deborah A., Sriskandan, Shiranee, Smeesters, Pierre R., Proft, Thomas, Steer, Andrew C., Walker, Mark J., Baker, Edward N., Baker, Michael G., Lennon, Diana, Dunbar, Rod and Fraser, John D. (2014). Working towards a Group A Streptococcal vaccine: report of a collaborative Trans-Tasman workshop. Vaccine, 32 (30), 3713-3720. doi: 10.1016/j.vaccine.2014.05.017

Working towards a Group A Streptococcal vaccine: report of a collaborative Trans-Tasman workshop

2014

Journal Article

The classical Lancefield antigen of Group A Streptococcus is a virulence determinant with implications for vaccine design

van Sorge, Nina M., Cole, Jason N., Kuipers, Kristen, Henningham, Anna, Aziz, Ramy K., Kasirer-Friede, Ana, Lin, Leo, Berends, Evelien T. M., Davies, Mark R., Dougan, Gordon, Zhang, Fan, Dahesh, Samira, Shaw, Laura, Gin, Jennifer, Cunningham, Madeleine, Merriman, Joseph A., Hutter, Julia, Lepenies, Bernd, Rooijakkers, Suzan H. M., Malley, Richard, Walker, Mark J., Shattil, Sanford J., Schlievert, Patrick M., Choudhury, Biswa and Nizet, Victor (2014). The classical Lancefield antigen of Group A Streptococcus is a virulence determinant with implications for vaccine design. Cell Host and Microbe, 15 (6), 729-740. doi: 10.1016/j.chom.2014.05.009

The classical Lancefield antigen of Group A Streptococcus is a virulence determinant with implications for vaccine design

2014

Journal Article

An antimicrobial role for zinc in innate immune defence against group A streptococcus

Ong, Cheryl-lynn Y., Gillen, Christine M., Barnett, Timothy C., Walker, Mark J. and McEwan, Alastair G. (2014). An antimicrobial role for zinc in innate immune defence against group A streptococcus. Journal of Infectious Diseases, 209 (10), 1500-1508. doi: 10.1093/infdis/jiu053

An antimicrobial role for zinc in innate immune defence against group A streptococcus

2014

Conference Publication

Nonencapsulated group A <i>Streptococcus</i> associated with human invasive disease

Henningham, Anna, Yamaguchi, Masaya, Aziz, Ramy, Kuipers, Kirsten, Dahesh, Samira, Yamaguchi, Yuka, Seymour, Lisa, Ben Zakour, Nouri, He, Lingjun, Smith, Helen, Grimwood, Keith, Beatson, Scott, Walker, Mark, Nizet, Victor and Cole, Jason (2014). Nonencapsulated group A Streptococcus associated with human invasive disease. Experimental Biology Meeting, San Diego Ca, Apr 26-30, 2014. BETHESDA: FEDERATION AMER SOC EXP BIOL.

Nonencapsulated group A <i>Streptococcus</i> associated with human invasive disease

2014

Journal Article

Site-restricted plasminogen activation mediated by group A streptococcal streptokinase variants

Cook, Simon M., Skora, Amanda, Walker, Mark J., Sanderson-Smith, Martina L. and McArthur, Jason D. (2014). Site-restricted plasminogen activation mediated by group A streptococcal streptokinase variants. Biochemical Journal, 458 (1), 23-31. doi: 10.1042/BJ20131305

Site-restricted plasminogen activation mediated by group A streptococcal streptokinase variants

2014

Journal Article

Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing

Ly, Diane, Taylor, Jude M., Tsatsaronis, James A., Monteleone, Mercedes M., Skora, Amanda S., Donald, Cortny A., Maddocks, Tracy, Nizet, Victor, West, Nicholas P., Ranson, Marie, Walker, Mark J., McArthur, Jason D. and Sanderson-Smith, Martina L. (2014). Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing. Journal of Innate Immunity, 6 (2), 240-250. doi: 10.1159/000353754

Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing

2014

Conference Publication

Genetics and virulence role of the classical group A Streptococcus Lancefield antigen

Cole, Jason, van Sorge, Nina, Kuipers, Kirsten, Henningham, Anna, Aziz, Ramy, Kasirer-Friede, Ana, Lin, Leo, Berends, Evelien, Davies, Mark, Dougan, Gordan, Zhang, Fan, Dahesh, Samira, Shaw, Laura, Gin, Jennifer, Cunningham, Madeleine, Merriman, Joseph, Rooijakkers, Suzan, Malley, Richard, Walker, Mark, Shattil, Sanford, Schlievert, Patrick, Choudhury, Biswa and Nizet, Victor (2014). Genetics and virulence role of the classical group A Streptococcus Lancefield antigen. Experimental Biology Meeting, San Diego Ca, 26-30 April 2014. Federation of American Societies for Experimental Biology.

Genetics and virulence role of the classical group A Streptococcus Lancefield antigen

2014

Journal Article

Disease manifestations and pathogenic mechanisms of group A Streptococcus

Walker, Mark J., Barnett, Timothy C., McArthur, Jason D., Cole, Jason N., Gillen, Christine M., Henningham, Anna, Sriprakash, K. S., Sanderson-Smith, Martina L. and Nizet, Victor (2014). Disease manifestations and pathogenic mechanisms of group A Streptococcus. Clinical Microbiology Reviews, 27 (2), 264-301. doi: 10.1128/CMR.00101-13

Disease manifestations and pathogenic mechanisms of group A Streptococcus

2013

Journal Article

Sequences of two related multiple antibiotic resistance virulence plasmids sharing a unique IS26-related molecular signature isolated from different Escherichia coli pathotypes from different hosts

Venturini, Carola, Hassan, Karl A., Chowdhury, Piklu Roy, Paulsen, Ian T., Walker, Mark J. and Djordjevic, Steven P. (2013). Sequences of two related multiple antibiotic resistance virulence plasmids sharing a unique IS26-related molecular signature isolated from different Escherichia coli pathotypes from different hosts. PLoS ONE, 8 (11) e78862, e78862.1-e78862.14. doi: 10.1371/journal.pone.0078862

Sequences of two related multiple antibiotic resistance virulence plasmids sharing a unique IS26-related molecular signature isolated from different Escherichia coli pathotypes from different hosts

2013

Journal Article

Extensive diversity of Streptococcus pyogenes in a remote human population reflects global-scale transmission rather than localised diversification

Towers, Rebecca J., Carapetis, Jonathan R., Currie, Bart J., Davies, Mark R., Walker, Mark J., Dougan, Gordon and Giffard, Philip M. (2013). Extensive diversity of Streptococcus pyogenes in a remote human population reflects global-scale transmission rather than localised diversification. PLoS One, 8 (9) e73851, e73851.1-e73851.6. doi: 10.1371/journal.pone.0073851

Extensive diversity of Streptococcus pyogenes in a remote human population reflects global-scale transmission rather than localised diversification

2013

Journal Article

Structure-informed design of an enzymatically inactive vaccine component for group A Streptococcus

Henningham, Anna, Ericsson, Daniel J., Langer, Karla, Casey, Lachlan W., Jovcevski, Blagojce, Singh Chhatwal, G., Aquilina, J. Andrew, Batzloff, Michael R., Kobe, Bostjan and Walker, Mark J. (2013). Structure-informed design of an enzymatically inactive vaccine component for group A Streptococcus. mBio, 4 (4) e00509-13. doi: 10.1128/mBio.00509-13

Structure-informed design of an enzymatically inactive vaccine component for group A Streptococcus

2013

Journal Article

Molecular characterization of endocarditis-associated Staphylococcus aureus

Nethercott, Cara, Mabbett, Amanda N., Totsika, Makrina, Peters, Paul, Ortiz, Juan C., Nimmo, Graeme R., Coombs, Geoffrey W., Walker, Mark J. and Schembri, Mark A. (2013). Molecular characterization of endocarditis-associated Staphylococcus aureus. Journal of Clinical Microbiology, 51 (7), 2131-2138. doi: 10.1128/JCM.00651-13

Molecular characterization of endocarditis-associated Staphylococcus aureus